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Medicina
Special Issues
New Insights into Hypertension and the Cardiovascular System
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New Insights into Hypertension and the Cardiovascular System

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Cardiology".

Deadline for manuscript submissions: 31 January 2025 | Viewed by 581

Special Issue Editor

Prof. Dr. Gwo-Ping Jong

E-Mail Website
Guest Editor
Department of Internal Medicine, Chung Shan Medical University Hospital and Chung Shan Medical University, Taichung, Taiwan
Interests: clinical epidemiology; risk assessment; clinical pharmacology; cardiovascular disease
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Cardiovascular diseases are one of the leading causes of death worldwide. The primary prevention of cardiovascular diseases has become a main goal to promote public health. Hypertension is a risk factor for cardiovascular diseases and is possibly the most powerful, modifiable risk factor for the development of cardiovascular diseases. Early detection and appropriate management are necessary to prevent both heart failure and cardiovascular diseases. Oxidative stress and chronic inflammation have been identified as being potentially responsible for the development of endothelial damage and vascular stiffness, which are two of the primum movens of hypertension and cardiovascular diseases. However, mechanisms, pathogenesis, sympathetic neural activity, risk factors, and differences in race/ethnicity have not been verified in hypertension-related cardiovascular disease. In this Special Issue, we emphasize the importance of the management and treatment of hypertension in the prevention of cardiovascular diseases and welcome all types of manuscripts (original articles and review articles).

Prof. Dr. Gwo-Ping Jong
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicina is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • hypertension
  • risk factors
  • oxidative stress
  • chronic inflammation
  • cardiovascular diseases

Published Papers (1 paper)

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Research

11 pages, 474 KiB  
Article
Cardiometabolic Risk Factors Related to Atrial Fibrillation and Metabolic Syndrome in the Pakistani Population
by Saira Rafaqat, Saima Sharif, Shagufta Naz, Sanja Gluscevic, Filiz Mercantepe, Ana Ninic and Aleksandra Klisic
Medicina 2024, 60(8), 1190; https://doi.org/10.3390/medicina60081190 - 23 Jul 2024
Viewed by 372
Abstract
Background and Objectives: This study aimed to examine the relationship between cardiometabolic risk factors and atrial fibrillation (AF) and the simultaneous presence of AF and metabolic syndrome (MetS) in the Pakistani population. Materials and Methods: A total of 690 subjects were [...] Read more.
Background and Objectives: This study aimed to examine the relationship between cardiometabolic risk factors and atrial fibrillation (AF) and the simultaneous presence of AF and metabolic syndrome (MetS) in the Pakistani population. Materials and Methods: A total of 690 subjects were enrolled (n = 230 patients with AF, n = 230 patients with AF and MetS, and n = 230 controls). The associations between cardiometabolic parameters and AF with and without MetS were analyzed by univariable and multivariable binary regression analyses. Results: Body mass index (BMI), fasting blood glucose (FBG), and triglycerides (TG) were independently positively correlated, but the glomerular filtration rate (GFR) and sodium were independently negatively correlated with AF. An increase in BMI, FBG, and TG levels by one unit measure increased the probability by 55.1%, 20.6%, and 1.3%, respectively, for the AF occurrence. A decrease in GFR and sodium levels increased the probability by 4.3% and 33.6%, respectively, for the AF occurrence. On the other hand, uric acid was independently negatively correlated, whereas sodium was independently positively correlated, with MetS and AF. A decrease in uric acid levels and an increase in sodium levels by 1 unit measure increased the probability for MetS and AF by 23.2% and 7.5%, respectively. Conclusions: Cost-effective and routinely measured parameters, i.e., BMI, FBG TG, GFR, and sodium levels, can be reliable indicators of AF, whereas serum uric acid and sodium levels are independently associated with AF and MetS in the Pakistani population. Timely recognition and the control of modifiable cardiometabolic risk factors are of great significance in the prevention of AF development. Full article
(This article belongs to the Special Issue New Insights into Hypertension and the Cardiovascular System)
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