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Infectious Disease Reports, Volume 15, Issue 6

2023 December - 12 articles

Cover Story: Drug-induced liver injury secondary to ATT treatment (TB-DILI) is reported in 2–28% of patients, varying with the definition, study sample, and treatment regimen. Here, we describe a retrospective descriptive case-series study, including a total of 10 patients who underwent liver biopsy in the course of TB-DILI. The histopathological diagnosis revealed liver injury due to DILI in 5/10 (50%) cases. In one case, a liver biopsy showed necrotizing granulomatous hepatitis. Severe and persistent elevations of liver transaminases and or hepatic cholestasis despite discontinuation of therapy and other suspected liver-related conditions were the indications of liver biopsy, which remains a valuable tool in the evaluation of selected patients with TB-DILI. The decision to perform a liver biopsy should be based on clinical judgment, considering the benefits and risks of the procedure. View this paper
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Articles (12)

  • Review
  • Open Access
13 Citations
3,699 Views
26 Pages

15 December 2023

The coronavirus disease 2019 (COVID-19), instigated by the zoonotic Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), rapidly transformed from an outbreak in Wuhan, China, into a widespread global pandemic. A significant post-infection co...

  • Case Report
  • Open Access
2 Citations
2,528 Views
11 Pages

Bacterial Pneumonia and Cryptogenic Pleuritis after Probable Monkeypox Virus Infection: A Case Report

  • Hubert Dawid Ciepłucha,
  • Mateusz Bożejko,
  • Paweł Piesiak,
  • Sylwia Serafińska and
  • Bartosz Szetela

13 December 2023

A large number of monkeypox (MPOX) cases have been reported in Europe and North America in 2022, and a new outbreak of this disease was declared. We describe a case of a patient with probable monkeypox during the height of this epidemic in Poland. Th...

  • Article
  • Open Access
1 Citations
2,233 Views
17 Pages

11 December 2023

In response to the COVID-19 pandemic, German public health authorities launched various infection control procedures. In line with this, anti-pandemic infection control was also implemented for German military and police deployments. The presented st...

  • Article
  • Open Access
5 Citations
2,596 Views
12 Pages

Bictegravir/Tenofovir Alafenamide/Emtricitabine: A Real-Life Experience in People Living with HIV (PLWH)

  • Anna Gidari,
  • Sara Benedetti,
  • Sara Tordi,
  • Anastasia Zoffoli,
  • Debora Altobelli,
  • Elisabetta Schiaroli,
  • Giuseppe Vittorio De Socio and
  • Daniela Francisci

11 December 2023

Background: Bictegravir (BIC), a recently introduced integrase inhibitor, is available in a single tablet regimen with tenofovir alafenamide (TAF) and emtricitabine (FTC) (BIC-STR). This study aimed to describe a real-life experience with BIC-STR. Me...

  • Brief Report
  • Open Access
5 Citations
2,145 Views
8 Pages

Latent Tuberculosis Infection and COVID-19: Analysis of a Cohort of Patients from Careggi University Hospital (Florence, Italy)

  • Francesca Mariotti,
  • Francesco Sponchiado,
  • Filippo Lagi,
  • Chiara Moroni,
  • Riccardo Paggi,
  • Seble Tekle Kiros,
  • Vittorio Miele,
  • Alessandro Bartoloni,
  • Jessica Mencarini and
  • The COCORA Working Group

10 December 2023

Data regarding the relationship between coronavirus disease (COVID-19) and active or latent tuberculosis (TB) are discordant. We conducted a retrospective study examining the impact of latent tuberculosis infection (LTBI) on the clinical progression...

  • Article
  • Open Access
5 Citations
2,028 Views
11 Pages

The Effects of Diabetes and Being Overweight on Patients with Post-COVID-19 Syndrome

  • Simona Kirbiš,
  • Nina Sobotkiewicz,
  • Barbara Antolinc Schaubach,
  • Jernej Završnik,
  • Peter Kokol,
  • Matej Završnik and
  • Helena Blažun Vošner

6 December 2023

In the aftermath of the COVID-19 pandemic, post-COVID-19 syndrome (PCS) remains a challenge and may continue to pose a major health problem in the future. Moreover, the influences of type 2 diabetes and being overweight on PCS remain unclear. This st...

  • Article
  • Open Access
2 Citations
2,798 Views
12 Pages

Utility of Liver Biopsy in the Diagnosis and Management of Possible Drug-Induced Liver Injury in Patients Receiving Antituberculosis Therapy: A Retrospective Study

  • Gina Gualano,
  • Drieda Zace,
  • Silvia Mosti,
  • Paola Mencarini,
  • Maria Musso,
  • Raffaella Libertone,
  • Carlotta Cerva,
  • Delia Goletti,
  • Alessia Rianda and
  • Fabrizio Palmieri
  • + 2 authors

28 November 2023

Background: Drug-induced liver injury (DILI) secondary to ATT treatment (TB-DILI) is reported in 2–28% of patients. We present here a series of clinical cases of suspected DILI arising during antituberculosis treatment, studied with the aid of...

  • Case Report
  • Open Access
8 Citations
2,734 Views
9 Pages

A Case Series of Potential Pediatric Cyanotoxin Exposures Associated with Harmful Algal Blooms in Northwest Ohio

  • Benjamin W. French,
  • Rajat Kaul,
  • Jerrin George,
  • Steven T. Haller,
  • David J. Kennedy and
  • Deepa Mukundan

20 November 2023

Cyanobacterial harmful algal blooms (CyanoHABs) are increasing in prevalence and severity in the Great Lakes region, as well as both globally and locally. CyanoHABs have the potential to cause adverse effects on human health due to the production of...

  • Article
  • Open Access
6 Citations
2,752 Views
9 Pages

Perioperative Urinary Catheter Use and Association to (Gram-Negative) Surgical Site Infection after Spine Surgery

  • Alexandre Ansorge,
  • Michael Betz,
  • Oliver Wetzel,
  • Marco Dimitri Burkhard,
  • Igor Dichovski,
  • Mazda Farshad and
  • Ilker Uçkay

10 November 2023

This study evaluates potential associations between the perioperative urinary catheter (UC) carriage and (Gram-negative) surgical site infections (SSIs) after spine surgery. It is a retrospective, single-center, case-control study stratifying group c...

  • Review
  • Open Access
19 Citations
8,728 Views
17 Pages

26 October 2023

Murine typhus is an acute febrile illness caused by Rickettsia typhi, an obligately intracellular Gram-negative coccobacillus. Rats (Rattus species) and their fleas (Xenopsylla cheopis) serve as the reservoir and vector of R. typhi, respectively. Hum...

  • Review
  • Open Access
3 Citations
10,571 Views
21 Pages

25 October 2023

In a rapidly evolving global landscape characterized by increased international travel, migration, and ecological shifts, this study sheds light on the emergence of protozoal and helminthic infections targeting the central nervous system (CNS) within...

  • Review
  • Open Access
10 Citations
6,798 Views
17 Pages

Oral Molnupiravir and Nirmatrelvir/Ritonavir for the Treatment of COVID-19: A Literature Review with a Focus on Real-World Evidence

  • Ioannis Karniadakis,
  • Nikolaos Mazonakis,
  • Constantinos Tsioutis,
  • Michail Papadakis,
  • Ioulia Markaki and
  • Nikolaos Spernovasilis

25 October 2023

Vaccines remain the cornerstone of medical prevention and are highly effective in reducing the risk of severe disease and death due to coronavirus disease 2019 (COVID-19). In the context of expanding the therapeutic armamentarium against COVID-19, mo...

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Infect. Dis. Rep. - ISSN 2036-7449