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Infectious Disease Reports, Volume 16, Issue 2

2024 April - 19 articles

Cover Story: Infectious diseases (IDs) are a leading cause of death. The diversity and adaptability of microbes represent a continuing risk to health.
In this article, we put in context how transdisciplinary research and team diversity were instrumental in changing the practice of medicine to fulfill the unmet needs of patients and health professionals.
Driven by curiosity, audacity, openness and simplicity (CAOS), our group’s integrated approach yielded better management of IDs through regulatory-cleared rapid molecular detection of pathogens and their resistance genes directly from clinical samples. We also discuss innovative infection prevention that has been long neglected.
Winning strategy: Addressing microbial diversity challenges with human diversity to better control IDs. View this paper
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Articles (19)

  • Review
  • Open Access
4 Citations
3,944 Views
27 Pages

18 April 2024

The coronavirus disease 2019 (COVID-19) has left a devasting effect on various regions globally. Africa has exceptionally high rates of other infectious diseases, such as tuberculosis (TB), human immunodeficiency virus (HIV), and malaria, and was not...

  • Article
  • Open Access
11 Citations
6,582 Views
13 Pages

Global Measles Surveillance: Trends, Challenges, and Implications for Public Health Interventions

  • Francesco Branda,
  • Marta Giovanetti,
  • Chiara Romano,
  • Domenico Benvenuto,
  • Alessandra Ciccozzi,
  • Daria Sanna,
  • Massimo Ciccozzi and
  • Fabio Scarpa

16 April 2024

Measles, a highly contagious disease primarily affecting children, carries serious health risks, including complications and mortality. Vaccination remains the most effective preventive measure against measles transmission. The COVID-19 pandemic has...

  • Article
  • Open Access
2 Citations
1,946 Views
11 Pages

Multicenter Study of the Effectiveness of Antifungal Stewardship Team Intervention for Candidemia in Japan in 2008–2021

  • Mieko Tokano,
  • Norihito Tarumoto,
  • Jun Sakai,
  • Kazuo Imai,
  • Sakaru Koizumi,
  • Haruka Karaushi,
  • Tamotsu Hatanaka,
  • Etsuko Kishi,
  • Masafumi Seki and
  • Shigefumi Maesaki
  • + 1 author

15 April 2024

Candidemia, linked to high mortality rates, requires prompt antifungal therapy for better outcomes. Treatment is structured as an action bundle, which is beneficial when followed closely. However, the Japanese action bundle lacks detailed guidance on...

  • Review
  • Open Access
11 Citations
3,798 Views
39 Pages

Respiratory Syncytial Virus Infections in Recipients of Bone Marrow Transplants: A Systematic Review and Meta-Analysis

  • Matteo Riccò,
  • Salvatore Parisi,
  • Silvia Corrado,
  • Federico Marchesi,
  • Marco Bottazzoli and
  • Davide Gori

29 March 2024

Human Respiratory Syncytial Virus (RSV) is a common cause of respiratory tract infections. Usually associated with infants and children, an increasing amount of evidence suggests that RSV can cause substantial morbidity and mortality in immunocomprom...

  • Review
  • Open Access
9 Citations
4,575 Views
19 Pages

Current Progress and Future Perspectives in Contact and Releasing-Type Antimicrobial Coatings of Orthopaedic Implants: A Systematic Review Analysis Emanated from In Vitro and In Vivo Models

  • Angelos Kaspiris,
  • Elias Vasiliadis,
  • Evangelia Pantazaka,
  • Ioanna Lianou,
  • Dimitra Melissaridou,
  • Matthaios Savvidis,
  • Fotios Panagopoulos,
  • Georgios Tsalimas,
  • Michail Vavourakis and
  • Spiros G. Pneumaticos
  • + 2 authors

26 March 2024

Background: Despite the expanding use of orthopedic devices and the application of strict pre- and postoperative protocols, the elimination of postoperative implant-related infections remains a challenge. Objectives: To identify and assess the in vit...

  • Commentary
  • Open Access
2 Citations
2,063 Views
9 Pages

On the SARS-CoV-2 Variants

  • Fabio Scarpa,
  • Francesco Branda,
  • Nicola Petrosillo and
  • Massimo Ciccozzi

26 March 2024

The evolutionary dynamics of viruses, particularly exemplified by SARS-CoV-2 during the ongoing COVID-19 pandemic, underscore the intricate interplay between genetics, host adaptation, and viral spread. This paper delves into the genetic evolution of...

  • Commentary
  • Open Access
6 Citations
2,568 Views
8 Pages

A One Health Platform for Future Epidemic Preparedness

  • Francesco Branda,
  • Fabio Scarpa,
  • Nicola Petrosillo and
  • Massimo Ciccozzi

20 March 2024

Here, we introduce the EpiConnect Intelligence Platform (ECIP), a platform facilitating rapid, transparent data sharing and analysis to support researchers and public health officials in Europe, with a focus on Italy. ECIP provides reliable, concise,...

  • Case Report
  • Open Access
1 Citations
2,631 Views
12 Pages

Whipple Disease Presenting as Isolated Transverse Myelitis with Permanent Neurological Damage in a Patient with Systemic Lupus Erythematosus: A Case Report of a Difficult Diagnosis with a Literature Review

  • Carolina Saffioti,
  • Marta Nebiolo,
  • Roberta Caorsi,
  • Alessio Mesini,
  • Mariasavina Severino,
  • Giacomo Brisca,
  • Elio Castagnola and
  • Marco Gattorno

19 March 2024

We describe an atypical case of Whipple disease exclusively involving the spinal cord in an adolescent receiving immunosuppressive therapy for systemic lupus erythematosus. The diagnosis was particularly difficult since lupus and Whipple disease can...

  • Brief Report
  • Open Access
1,562 Views
9 Pages

A Vulnerability Index to Assess the Risk of SARS-CoV-2-Related Hospitalization/Death: Urgent Need for an Update after Diffusion of Anti-COVID Vaccines

  • Francesco Lapi,
  • Ettore Marconi,
  • Alexander Domnich,
  • Iacopo Cricelli,
  • Alessandro Rossi,
  • Ignazio Grattagliano,
  • Giancarlo Icardi and
  • Claudio Cricelli

15 March 2024

Background: There are algorithms to predict the risk of SARS-CoV-2-related complications. Given the spread of anti-COVID vaccination, which sensibly modified the burden of risk of the infection, these tools need to be re-calibrated. Therefore, we upd...

  • Case Report
  • Open Access
3 Citations
3,772 Views
11 Pages

An Aminoglycoside-Sparing Regimen with Double Beta-Lactam to Successfully Treat Granulicatella adiacens Prosthetic Aortic Valve Endocarditis—Time to Change Paradigm?

  • Alberto Pagotto,
  • Floriana Campanile,
  • Paola Conti,
  • Francesca Prataviera,
  • Paola Della Siega,
  • Sarah Flammini,
  • Simone Giuliano,
  • Luca Martini,
  • Davide Pecori and
  • Carlo Tascini
  • + 3 authors

14 March 2024

(1) Background: Granulicatella adiacens is a former nutritionally variant streptococci (NVS). NVS infective endocarditis (IE) is generally characterized by a higher rate of morbidity and mortality, partially due to difficulties in choosing the most a...

  • Article
  • Open Access
3 Citations
2,183 Views
10 Pages

Risk Factors for Late HIV Presentation in Patients Treated at a Single Belgian Reference Centre from 2018 to 2022

  • Damien Scaia,
  • Karine Fombellida,
  • Nathalie Maes,
  • Majdouline El Moussaoui and
  • Gilles Darcis

14 March 2024

A late HIV diagnosis is associated with increased mortality and morbidity, increased healthcare costs and increased onward viral transmission. In this regard, we retrospectively analysed the characteristics of patients who presented for care at our c...

  • Article
  • Open Access
3 Citations
2,723 Views
11 Pages

13 March 2024

Non-ventilator associated hospital-acquired pneumonia (nvHAP) is a common nosocomial infection, but little is known about the outcomes of patients with nvHAP and the risk factors for adverse outcomes. In this retrospective study conducted in a Swiss...

  • Review
  • Open Access
6 Citations
7,955 Views
12 Pages

Tackling Infectious Diseases with Rapid Molecular Diagnosis and Innovative Prevention

  • Rabeea F. Omar,
  • Maurice Boissinot,
  • Ann Huletsky and
  • Michel G. Bergeron

5 March 2024

Infectious diseases (IDs) are a leading cause of death. The diversity and adaptability of microbes represent a continuing risk to health. Combining vision with passion, our transdisciplinary medical research team has been focussing its work on the be...

  • Review
  • Open Access
9 Citations
3,546 Views
16 Pages

Pulmonary Involvement in Recurrent Respiratory Papillomatosis: A Systematic Review

  • Illari Sechi,
  • Narcisa Muresu,
  • Biagio Di Lorenzo,
  • Laura Saderi,
  • Mariangela Puci,
  • Stefano Aliberti,
  • Ivana Maida,
  • Michele Mondoni,
  • Andrea Piana and
  • Giovanni Sotgiu

28 February 2024

Recurrent respiratory papillomatosis (RRP) is a non-malignant disease, characterized by the production of wart-like growths in the respiratory tract, affecting both young people and adults (juvenile-onset recurrent respiratory papillomatosis, JORRP,...

  • Article
  • Open Access
1 Citations
1,837 Views
11 Pages

Radiological Explorations of Patients with Upper or Febrile Urinary Tract Infection

  • Katia Vanolli,
  • Mike Libasse Jost,
  • Olivier Clerc,
  • Daniel Genné and
  • Gregor John

23 February 2024

Recent European Association of Urology (EAU) guidelines and a clinical prediction rule developed by Van Nieuwkoop et al. suggest simple criteria for performing radiological imaging for patients with a febrile urinary tract infection (UTI). We analyse...

  • Brief Report
  • Open Access
4 Citations
4,784 Views
8 Pages

The Prevalence, Risk Factors, and Antimicrobial Resistance Determinants of Helicobacter pylori Detected in Dyspeptic Patients in North–Central Bangladesh

  • Syeda Jannatul Ferdaus,
  • Shyamal Kumar Paul,
  • Syeda Anjuman Nasreen,
  • Nazia Haque,
  • Mohammad Sadekuzzaman,
  • Mohammad Reazul Karim,
  • Syed Mahmudul Islam,
  • Abdullah Al Mamun,
  • Fardousi Akter Sathi and
  • Nobumichi Kobayashi
  • + 3 authors

22 February 2024

Chronic infection of Helicobacter pylori represents a key factor in the etiology of gastrointestinal diseases, with high endemicity in South Asia. The present study aimed to determine the prevalence of H. pylori among dyspeptic patients in north&ndas...

  • Article
  • Open Access
8 Citations
3,145 Views
11 Pages

22 February 2024

Monkeypox (MPOX) is a viral zoonotic disease affecting endemically the Central and Western regions of Africa. The ongoing outbreak in non-endemic countries has made this disease a global concern. While no cases have been reported in Algeria, it is im...

  • Systematic Review
  • Open Access
18 Citations
5,288 Views
16 Pages

Hemophagocytic Lymphohistiocytosis (HLH) in Patients with Tick-Borne Illness: A Scoping Review of 98 Cases

  • Dorde Jevtic,
  • Marilia Dagnon da Silva,
  • Alberto Busmail Haylock,
  • Charles W. Nordstrom,
  • Stevan Oluic,
  • Nikola Pantic,
  • Milan Nikolajevic,
  • Nikola Nikolajevic,
  • Magdalena Kotseva and
  • Igor Dumic

21 February 2024

Hemophagocytic lymphohistiocytosis (HLH) secondary to tick-borne infections is a rare but potentially life-threatening syndrome. We performed a scoping review according to PRISMA guidelines to systematically analyze the existing literature on the top...

  • Article
  • Open Access
1 Citations
2,285 Views
12 Pages

20 February 2024

Excess mortality is often used to estimate the effect of a certain crisis on the population. It is defined as the number of deaths during a crisis exceeding the expected number based on historical trends. Here, we calculated excess mortality due to t...

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Infect. Dis. Rep. - ISSN 2036-7449