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Nutrients, Volume 11, Issue 4

2019 April - 233 articles

Cover Story: An increasing amount of evidence points towards migraine being a response to cerebral energy deficiency or oxidative stress levels that exceed antioxidant capacity. The ketogenic diet (KD), a diet mimicking fasting that leads to the elevation of ketone bodies (KBs), is a therapeutic intervention targeting cerebral metabolism that has recently shown great promise in the prevention of migraine. KBs are an alternative fuel source for the brain and are hence likely able to circumvent some of the abnormalities in glucose metabolism and transport found in migraine. As signalling molecules, they have the potential to positively influence other pathways commonly believed to be part of migraine pathophysiology. This review will describe the mechanisms by which the presence of KBs, D-BHB in particular, could influence those migraine pathophysiological mechanisms. View this paper.
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Articles (233)

  • Article
  • Open Access
33 Citations
7,051 Views
16 Pages

25 April 2019

Maternal dietary quality during pregnancy is associated with offspring outcomes. These associations have not been examined in three-generation families. We investigated associations between parental and grandparental dietary quality, determined by he...

  • Article
  • Open Access
8 Citations
5,880 Views
17 Pages

Local In Vivo Measures of Muscle Lipid and Oxygen Consumption Change in Response to Combined Vitamin D Repletion and Aerobic Training in Older Adults

  • D. Travis Thomas,
  • David M. Schnell,
  • Maja Redzic,
  • Mingjun Zhao,
  • Hideat Abraha,
  • Danielle Jones,
  • Howard Brim and
  • Guoqiang Yu

25 April 2019

Intramyocellular (IMCL), extramyocellular lipid (EMCL), and vitamin D deficiency are associated with muscle metabolic dysfunction. This study compared the change in [IMCL]:[EMCL] following the combined treatment of vitamin D and aerobic training (DAT...

  • Review
  • Open Access
58 Citations
17,137 Views
20 Pages

Dietary Factors in Sulfur Metabolism and Pathogenesis of Ulcerative Colitis

  • Levi M. Teigen,
  • Zhuo Geng,
  • Michael J. Sadowsky,
  • Byron P. Vaughn,
  • Matthew J. Hamilton and
  • Alexander Khoruts

25 April 2019

The biogeography of inflammation in ulcerative colitis (UC) suggests a proximal to distal concentration gradient of a toxin. Hydrogen sulfide (H2S) has long been considered one such toxin candidate, and dietary sulfur along with the abundance of sulf...

  • Article
  • Open Access
26 Citations
6,709 Views
12 Pages

Decreased Appetite is Associated with Sarcopenia-Related Outcomes in Acute Hospitalized Older Adults

  • Carliene van Dronkelaar,
  • Michael Tieland,
  • Jesse J. Aarden,
  • Lucienne A. Reichardt,
  • Rosanne van Seben,
  • Marike van der Schaaf,
  • Martin van der Esch,
  • Raoul H. H. Engelbert,
  • Jos W. R. Twisk and
  • on behalf of the Hospital-ADL Study Group
  • + 2 authors

25 April 2019

Decreased appetite is one of the main risk factors of malnutrition. Little is known on how appetite changes during hospitalization and after discharge and how it relates with sarcopenia-related outcomes. We analyzed data of the Hospital-ADL study, a...

  • Article
  • Open Access
31 Citations
7,159 Views
15 Pages

Reproducibility and Validity of a Short Food Frequency Questionnaire for Dietary Assessment in Children Aged 7–9 Years in Spain

  • Jesus Vioque,
  • Manuela Garcia-de-la-Hera,
  • Sandra Gonzalez-Palacios,
  • Laura Torres-Collado,
  • Leyre Notario-Barandiaran,
  • Alejandro Oncina-Canovas,
  • Raquel Soler-Blasco,
  • Manuel Lozano,
  • Andrea Beneito and
  • Eva-Maria Navarrete-Muñoz

25 April 2019

The purpose of this study was to examine if the short semi-quantitative food frequency questionnaire (FFQ) is a reliable and valid tool to assess the diet of Spanish children aged 7–9 years. We collected data from 156 children of the birth coho...

  • Article
  • Open Access
16 Citations
5,959 Views
10 Pages

25 April 2019

Over the past decades, periodontitis has become a rising health problem and caused various diseases. In the many studies shows that some extracts and compound to the prevention and treatment of periodontitis. This study focuses on the effects of inhi...

  • Feature Paper
  • Article
  • Open Access
28 Citations
9,645 Views
19 Pages

Association of Selenoprotein and Selenium Pathway Genotypes with Risk of Colorectal Cancer and Interaction with Selenium Status

  • Veronika Fedirko,
  • Mazda Jenab,
  • Catherine Méplan,
  • Jeb S. Jones,
  • Wanzhe Zhu,
  • Lutz Schomburg,
  • Afshan Siddiq,
  • Sandra Hybsier,
  • Kim Overvad and
  • David J. Hughes
  • + 37 authors

25 April 2019

Selenoprotein genetic variations and suboptimal selenium (Se) levels may contribute to the risk of colorectal cancer (CRC) development. We examined the association between CRC risk and genotype for single nucleotide polymorphisms (SNPs) in selenoprot...

  • Article
  • Open Access
50 Citations
7,136 Views
14 Pages

Hesperidin Alleviates Methotrexate-Induced Memory Deficits via Hippocampal Neurogenesis in Adult Rats

  • Salinee Naewla,
  • Apiwat Sirichoat,
  • Wanassanan Pannangrong,
  • Pornthip Chaisawang,
  • Peter Wigmore and
  • Jariya Umka Welbat

25 April 2019

Methotrexate (MTX), a folic acid antagonist, is widely used in cancer treatment. However, treatment with MTX reduces hippocampal neurogenesis, leading to memory deficits. Hesperidin (Hsd) is a flavonoid glycoside that promotes anti-inflammation, acts...

  • Article
  • Open Access
34 Citations
9,462 Views
13 Pages

25 April 2019

We aimed to explore the effects of caffeinated gel ingestion on neuromuscular performance in resistance-trained men. The participants (n = 17; mean ± standard deviation (SD): age 23 ± 2 years, height 183 ± 5 cm, body mass 83 &plu...

  • Feature Paper
  • Article
  • Open Access
27 Citations
13,257 Views
12 Pages

Association of Full Breastfeeding Duration with Postpartum Weight Retention in a Cohort of Predominantly Breastfeeding Women

  • Muna J. Tahir,
  • Jacob L. Haapala,
  • Laurie P. Foster,
  • Katy M. Duncan,
  • April M. Teague,
  • Elyse O. Kharbanda,
  • Patricia M. McGovern,
  • Kara M. Whitaker,
  • Kathleen M. Rasmussen and
  • Ellen W. Demerath
  • + 3 authors

25 April 2019

Full breastfeeding (FBF) is promoted as effective for losing pregnancy weight during the postpartum period. This study evaluated whether longer FBF is associated with lower maternal postpartum weight retention (PPWR) as compared to a shorter FBF dura...

  • Article
  • Open Access
13 Citations
8,464 Views
11 Pages

Effect of High Fiber Cereal Intake on Satiety and Gastrointestinal Symptoms during Ramadan

  • Amjad H. Jarrar,
  • Jeannette M. Beasley,
  • Eric O. Ohuma,
  • Leila Cheikh Ismail,
  • Dina A. Qeshta,
  • Maysm N. Mohamad and
  • Ayesha S. Al Dhaheri

25 April 2019

(1) Background: Fasting during Ramadan involves large changes in daily eating patterns which strongly impacts the daily biorhythm and challenges the regular function of the digestive tract. The aim of this study was to assess satiety, bowel habits, b...

  • Article
  • Open Access
10 Citations
5,127 Views
14 Pages

Soluble CD163-Associated Dietary Patterns and the Risk of Metabolic Syndrome

  • Tzu-Yu Hu,
  • Shin-Yng Lee,
  • Chun-Kuang Shih,
  • Meng-Jung Chou,
  • Meng-Chieh Wu,
  • I-Chun Teng,
  • Chyi-Huey Bai,
  • Nindy Sabrina,
  • Alexey A. Tinkov and
  • Jung-Su Chang
  • + 1 author

25 April 2019

Elevated soluble cluster of differentiation 163 (sCD163) concentrations, a marker of macrophage activation, are associated with obesity. Weight reduction decreases circulating CD163 levels, and changes in sCD163 levels are associated with improved me...

  • Article
  • Open Access
20 Citations
6,444 Views
14 Pages

Capsaicin Analogues Derived from n-3 Polyunsaturated Fatty Acids (PUFAs) Reduce Inflammatory Activity of Macrophages and Stimulate Insulin Secretion by β-Cells In Vitro

  • Erika Cione,
  • Pierluigi Plastina,
  • Attilio Pingitore,
  • Mariarita Perri,
  • Maria Cristina Caroleo,
  • Alessia Fazio,
  • Renger Witkamp and
  • Jocelijn Meijerink

24 April 2019

In this study, two capsaicin analogues, N-eicosapentaenoyl vanillylamine (EPVA) and N-docosahexaenoyl vanillylamine (DHVA), were enzymatically synthesized from their corresponding n-3 long chain polyunsaturated fatty acids eicosapentaenoic acid (EPA)...

  • Article
  • Open Access
3 Citations
4,786 Views
12 Pages

Mean Dietary Salt Intake in Vanuatu: A Population Survey of 755 Participants on Efate Island

  • Katherine Paterson,
  • Nerida Hinge,
  • Emalie Sparks,
  • Kathy Trieu,
  • Joseph Alvin Santos,
  • Len Tarivonda,
  • Wendy Snowdon,
  • Jacqui Webster and
  • Claire Johnson

24 April 2019

Non-communicable diseases are responsible for 63% of global deaths, with a higher burden in low- and middle-income countries. Hypertension is the leading cause of cardiovascular-disease-related deaths worldwide, and approximately 1.7 million deaths a...

  • Article
  • Open Access
37 Citations
6,241 Views
19 Pages

24 April 2019

Hepatic steatosis, an early stage of non-alcoholic fatty liver disease, is commonly present in obesity and type 2 diabetes, and is associated with reduced hepatic omega-3 polyunsaturated fatty acid (n3-PUFA) status that impacts on the anti-inflammato...

  • Article
  • Open Access
15 Citations
5,381 Views
10 Pages

24 April 2019

Iron absorption was impaired in the presence of sub-clinical inflammation (SCI) and might hamper the effect of iron supplementation. The purpose of the study was to identify the influence of SCI on iron supplementation. A randomized, double-blinded,...

  • Article
  • Open Access
12 Citations
9,535 Views
9 Pages

Biotin Is Required for the Zinc Homeostasis in the Skin

  • Youichi Ogawa,
  • Manao Kinoshita,
  • Takuya Sato,
  • Shinji Shimada and
  • Tatsuyoshi Kawamura

24 April 2019

Patients with biotin deficiency present symptoms that are similar to those in patients with acrodermatitis enteropathica (inherent zinc deficiency). However, the association between biotin and zinc deficiency remains unknown. We have previously shown...

  • Article
  • Open Access
44 Citations
8,209 Views
14 Pages

Differences in Maternal Immunoglobulins within Mother’s Own Breast Milk and Donor Breast Milk and across Digestion in Preterm Infants

  • Veronique Demers-Mathieu,
  • Robert K. Huston,
  • Andi M. Markell,
  • Elizabeth A. McCulley,
  • Rachel L. Martin,
  • Melinda Spooner and
  • David C. Dallas

24 April 2019

Maternal antibody transfer to the newborn provides essential support for the infant’s naïve immune system. Preterm infants normally receive maternal antibodies through mother’s own breast milk (MBM) or, when mothers are unable to pro...

  • Article
  • Open Access
15 Citations
4,964 Views
18 Pages

24 April 2019

Qualified health claims (QHC) describe diet–disease relationships and summarize the quality and strength of evidence for a claim. Companies assert that QHCs increase sales and take legal action to ensure claims reflect their interests. Yet, there is...

  • Article
  • Open Access
13 Citations
5,674 Views
13 Pages

Weight Change and Cardiometabolic Outcomes in Postpartum Women with History of Gestational Diabetes

  • Siew Lim,
  • Vincent L. Versace,
  • Sharleen O’Reilly,
  • Edward Janus and
  • James Dunbar

24 April 2019

Weight gain after childbirth is a significant risk factor for type 2 diabetes (T2DM) development after gestational diabetes mellitus (GDM). The level of weight loss achieved in diabetes prevention programs for women after GDM is often low but its eff...

  • Review
  • Open Access
269 Citations
37,459 Views
45 Pages

Precision Nutrition and the Microbiome, Part I: Current State of the Science

  • Susan Mills,
  • Catherine Stanton,
  • Jonathan A. Lane,
  • Graeme J. Smith and
  • R. Paul Ross

24 April 2019

The gut microbiota is a highly complex community which evolves and adapts to its host over a lifetime. It has been described as a virtual organ owing to the myriad of functions it performs, including the production of bioactive metabolites, regulatio...

  • Article
  • Open Access
10 Citations
5,355 Views
13 Pages

Exposure to Vitamin D Fortification Policy in Prenatal Life and the Risk of Childhood Asthma: Results from the D-Tect Study

  • Fanney Thorsteinsdottir,
  • Ekaterina Maslova,
  • Ramune Jacobsen,
  • Peder Frederiksen,
  • Amélie Keller,
  • Vibeke Backer and
  • Berit Lilienthal Heitmann

24 April 2019

Prenatal vitamin D insufficiency may be associated with an increased risk of developing childhood asthma. Results from epidemiological studies are conflicting and limited by short follow-up and small sample sizes. The objective of this study was to e...

  • Article
  • Open Access
25 Citations
7,071 Views
20 Pages

24 April 2019

Obesity has reached epidemic proportions, motivating research into the underlying mechanisms. Olfaction is a powerful mediator of food consumption, and obesity has been associated with altered olfactory sensitivity. The current study used an event-re...

  • Feature Paper
  • Article
  • Open Access
12 Citations
5,431 Views
13 Pages

Cognitive Training Therapy Improves the Effect of Hypocaloric Treatment on Subjects with Overweight/Obesity: A Randomised Clinical Trial

  • Joaquín S. Galindo Muñoz,
  • Juana María Morillas-Ruiz,
  • María Gómez Gallego,
  • Inmaculada Díaz Soler,
  • María del Carmen Barberá Ortega,
  • Carlos M. Martínez and
  • Juan José Hernández Morante

24 April 2019

Obesity has been associated with impaired cognitive performance. This study aimed to determine whether improvements in cognitive function may contribute to higher weight loss in patients with obesity. In this randomised, 12-week trial, participants w...

  • Article
  • Open Access
30 Citations
6,206 Views
13 Pages

24 April 2019

The study aimed to investigate the immunomodulatory activity of oligopeptides derived from oat (Avena nuda L.) (OOPs). Healthy female BALB/c mice were randomly assigned to five groups, given deionized water (control) and 0.25, 0.5, 1.0, and 2.0 g/kg...

  • Article
  • Open Access
36 Citations
11,910 Views
18 Pages

Food Insecure College Students and Objective Measurements of Their Unused Meal Plans

  • Irene van Woerden,
  • Daniel Hruschka,
  • Sonia Vega-Lόpez,
  • David R. Schaefer,
  • Marc Adams and
  • Meg Bruening

23 April 2019

Some researchers have proposed the prevalence of food insecurity among college students is high due to students’ meal plans providing insufficient meals. The association between college students’ food security status and their meal plans...

  • Article
  • Open Access
25 Citations
7,520 Views
16 Pages

23 April 2019

Young adult university students are a priority population for nutrition intervention. This study assessed the feasibility and preliminary efficacy of the EATS (Eating Advice to Students) brief (i.e., single use) web-based nutrition intervention for y...

  • Article
  • Open Access
33 Citations
11,410 Views
14 Pages

Cordycepin, an Active Constituent of Nutrient Powerhouse and Potential Medicinal Mushroom Cordyceps militaris Linn., Ameliorates Age-Related Testicular Dysfunction in Rats

  • Spandana Rajendra Kopalli,
  • Kyu-Min Cha,
  • Sang-Ho Lee,
  • Seock-Yeon Hwang,
  • Young-Joo Lee,
  • Sushruta Koppula and
  • Si-Kwan Kim

23 April 2019

Age-related male sexual dysfunction covers a wide variety of issues, together with spermatogenic and testicular impairment. In the present work, the effects of cordycepin (COR), an active constituent of a nutrient powerhouse Cordyceps militaris Linn,...

  • Article
  • Open Access
29 Citations
5,908 Views
18 Pages

Delayed-Type Hypersensitivity Underlying Casein Allergy Is Suppressed by Extracellular Vesicles Carrying miRNA-150

  • Magdalena Wąsik,
  • Katarzyna Nazimek,
  • Bernadeta Nowak,
  • Philip W. Askenase and
  • Krzysztof Bryniarski

23 April 2019

In patients with non-IgE-mediated milk allergy, a cellular mechanism of delayed-type hypersensitivity (DTH) is considered. Recent findings prove that cell-mediated reactions can be antigen-specifically inhibited by extracellular vesicles (EVs) carryi...

  • Communication
  • Open Access
9 Citations
3,941 Views
10 Pages

23 April 2019

Brassica vegetables such as cabbage or pak choi contain alkenyl glucosinolates which can release epithionitriles and to a lesser degree isothiocyanates upon enzymatic hydrolysis. Here, for the first time, the metabolism of an epithionitrile was inves...

  • Article
  • Open Access
13 Citations
18,664 Views
12 Pages

Beer or Ethanol Effects on the Body Composition Response to High-Intensity Interval Training. The BEER-HIIT Study

  • Cristina Molina-Hidalgo,
  • Alejandro De-la-O,
  • Lucas Jurado-Fasoli,
  • Francisco J. Amaro-Gahete and
  • Manuel J. Castillo

23 April 2019

High-intensity interval training (HIIT) is promoted as a time-efficient strategy to improve body composition but concomitant beer intake, which is common among physically active individuals, may interfere with these effects. The primary aim of this s...

  • Feature Paper
  • Article
  • Open Access
3 Citations
4,630 Views
12 Pages

23 April 2019

The consequences of maternal experience of Domestic Violence (DV) on their children’s cardio-metabolic risk factors are unclear. We aimed to assess if maternal exposure to any or a specific form of DV (i.e., physical, sexual, emotional and cont...

  • Article
  • Open Access
23 Citations
6,042 Views
13 Pages

Changes in Pancreatic Fat Content Following Diet-Induced Weight Loss

  • Yixin Jiang,
  • Manuela Spurny,
  • Ruth Schübel,
  • Tobias Nonnenmacher,
  • Christopher L. Schlett,
  • Oyunbileg von Stackelberg,
  • Cornelia M. Ulrich,
  • Rudolf Kaaks,
  • Hans-Ulrich Kauczor and
  • Johanna Nattenmüller
  • + 1 author

23 April 2019

Background: Obesity can lead to ectopic pancreatic fat accumulation and increase the risk for type 2 diabetes. Smaller intervention trials have shown a decrease in pancreatic fat content (PFC) with weight loss, and we intended to investigate the effe...

  • Article
  • Open Access
23 Citations
20,418 Views
11 Pages

Dietary Calcium Intake and Hypertension: Importance of Serum Concentrations of 25-Hydroxyvitamin D

  • Haruki Nakamura,
  • Hiromasa Tsujiguchi,
  • Akinori Hara,
  • Yasuhiro Kambayashi,
  • Sakae Miyagi,
  • Thao Thi Thu Nguyen,
  • Keita Suzuki,
  • Yuichi Tao,
  • Yuriko Sakamoto and
  • Hiroyuki Nakamura
  • + 2 authors

23 April 2019

The relationship among dietary calcium, hypertension and vitamin D status currently remains unclear. This population-based cross-sectional study examined the association between dietary calcium intake and hypertension and the influence of serum conce...

  • Article
  • Open Access
17 Citations
6,851 Views
13 Pages

23 April 2019

The AUSNUT 2011–13 food composition database was expanded to include Australian choline values. The development began with a systematic literature review of published studies. Analytical data from the food studies were extracted and aligned wit...

  • Article
  • Open Access
8 Citations
5,574 Views
12 Pages

Effect of Topically Applied Wikstroemia dolichantha Diels on the Development of Atopic Dermatitis-Like Skin Symptoms in Mice

  • Jonghwan Jegal,
  • No-June Park,
  • Tae-Young Kim,
  • Sangho Choi,
  • Sang Woo Lee,
  • Jin Hang,
  • Su-Nam Kim and
  • Min Hye Yang

23 April 2019

Plants of the genus Wikstroemia are traditionally used to treat inflammatory diseases like bronchitis and rheumatoid arthritis. In the present study, the anti-atopic effects of an EtOH extract of Wikstroemia dolichantha (WDE) on oxazolone- and DNCB (...

  • Article
  • Open Access
12 Citations
5,047 Views
14 Pages

Factors Associated with Increased Alpha-Tocopherol Content in Milk in Response to Maternal Supplementation with 800 IU of Vitamin E

  • Amanda de Sousa Rebouças,
  • Ana Gabriella Costa Lemos da Silva,
  • Amanda Freitas de Oliveira,
  • Lorena Thalia Pereira da Silva,
  • Vanessa de Freitas Felgueiras,
  • Marina Sampaio Cruz,
  • Vivian Nogueira Silbiger,
  • Karla Danielly da Silva Ribeiro and
  • Roberto Dimenstein

22 April 2019

Background: Vitamin E supplementation might represent an efficient strategy to increase the vitamin E content in milk. The present study aimed to evaluate the impact of supplementation with 800 IU RRR-alpha-tocopherol on the alpha-tocopherol content...

  • Article
  • Open Access
60 Citations
7,212 Views
17 Pages

In Vitro Probiotic and Antioxidant Potential of Lactococcus lactis subsp. cremoris LL95 and Its Effect in Mice Behaviour

  • Juliana B. Ramalho,
  • Melina B. Soares,
  • Cristiano C. Spiazzi,
  • Diogo F. Bicca,
  • Vanessa M. Soares,
  • Juliano G. Pereira,
  • Wladimir P. da Silva,
  • Carla P. Sehn and
  • Francielli W. S. Cibin

22 April 2019

The composition of intestinal microbiota is widely believed to not only affect gut health but also influence behaviour. This study aimed to evaluate the probiotic characteristics, antioxidant activity, and antidepressant- and anxiolytic-like activiti...

  • Article
  • Open Access
17 Citations
4,121 Views
11 Pages

Associations of Lipophilic Micronutrients with Physical and Cognitive Fitness in Persons with Mild Cognitive Impairment

  • Perihan Gerger,
  • Roopa Kalsank Pai,
  • Tim Stuckenschneider,
  • Julia Falkenreck,
  • Hannah Weigert,
  • Wilhelm Stahl,
  • Bernd Weber,
  • Gereon Nelles,
  • Liana Spazzafumo and
  • M. Cristina Polidori
  • + 1 author

22 April 2019

Age-associated cognitive impairment in general and dementia in particular are a global concern. Preventive lifestyle strategies are highly used but there is a lack of information on the reciprocal relationships between nutrition biomarkers and measur...

  • Article
  • Open Access
40 Citations
4,423 Views
11 Pages

Exposure to Famine During Early Life and Abdominal Obesity in Adulthood: Findings from the Great Chinese Famine During 1959–1961

  • Dan Liu,
  • Dong-mei Yu,
  • Li-yun Zhao,
  • Hong-yun Fang,
  • Jian Zhang,
  • Jing-zhong Wang,
  • Zhen-yu Yang and
  • Wen-hua Zhao

22 April 2019

Undernutrition during early life may lead to obesity in adulthood. This study was conducted to examine the relationship between famine exposure during early life and the risk of abdominal obesity in adulthood. A total of 18,984 and 16,594 adults were...

  • Article
  • Open Access
25 Citations
7,667 Views
13 Pages

21 April 2019

Because age-related hearing loss (ARHL) is irreversible, prevention is very important. Thus, investigating modifying factors that help prevent ARHL is critical for the elderly. Nutritional status or nutritional factors for the elderly are known to be...

  • Review
  • Open Access
36 Citations
7,707 Views
18 Pages

21 April 2019

Skeletal muscle (SM) mass, the chief component of the structural compartment belonging to lean body mass (LBM), undergoes sarcopenia with increasing age. Decreased SM in elderly persons is a naturally occurring process that may be accelerated by acut...

  • Brief Report
  • Open Access
5 Citations
3,122 Views
8 Pages

21 April 2019

An understanding of the source of children’s foods and drinks is needed to identify the best intervention points for programs and policies aimed at improving children’s diets. The mean number and type of eating occasions and the relative...

  • Article
  • Open Access
34 Citations
5,072 Views
10 Pages

Clinical Significance of Serum Glutamine Level in Patients with Colorectal Cancer

  • Hang Huong Ling,
  • Yi-Ping Pan,
  • Chung-Wei Fan,
  • Wen-Ko Tseng,
  • Jen-Seng Huang,
  • Tsung-Han Wu,
  • Wen-Chi Chou,
  • Cheng-Hsu Wang,
  • Kun-Yun Yeh and
  • Pei-Hung Chang

21 April 2019

Limited studies have assessed the associations of pretreatment serum glutamine level with clinicopathological characteristics and prognosis of colorectal cancer (CRC) patients. This study focuses on clarifying the clinical significance of baseline se...

  • Article
  • Open Access
12 Citations
6,745 Views
16 Pages

Uncontrolled Eating during Pregnancy Predicts Fetal Growth: The Healthy Mom Zone Trial

  • Jennifer S. Savage,
  • Emily E. Hohman,
  • Katherine M. McNitt,
  • Abigail M. Pauley,
  • Krista S. Leonard,
  • Tricia Turner,
  • Jaimey M. Pauli,
  • Alison D. Gernand,
  • Daniel E. Rivera and
  • Danielle Symons Downs

21 April 2019

Excess maternal weight gain during pregnancy elevates infants’ risk for macrosomia and early-onset obesity. Eating behavior is also related to weight gain, but the relationship to fetal growth is unclear. We examined whether Healthy Mom Zone, a...

  • Brief Report
  • Open Access
12 Citations
5,043 Views
6 Pages

Feralgine™ a New Approach for Iron Deficiency Anemia in Celiac Patients

  • Laura Giancotti,
  • Valentina Talarico,
  • Giuseppe Antonio Mazza,
  • Santina Marrazzo,
  • Pietro Gangemi,
  • Roberto Miniero and
  • Marco Bertini

20 April 2019

Background: Celiac disease (CD) is an immunologically-mediated disorder characterized by duodenal mucosa villi atrophy. Iron absorption is usually reduced in celiac patients making every kind of oral iron treatment unhelpful because of malasorption....

  • Article
  • Open Access
7 Citations
4,692 Views
9 Pages

Comparison of Clinical Outcomes in Surgical Patients Subjected to CIPA Nutrition Screening and Treatment versus Standard Care

  • José Pablo Suárez-Llanos,
  • Adriá Rosat-Rodrigo,
  • Jennifer García-Niebla,
  • Laura Vallejo-Torres,
  • Irina Delgado-Brito,
  • Miguel A. García-Bello,
  • Francisca Pereyra-García-Castro and
  • Manuel A. Barrera-Gómez

20 April 2019

Malnutrition is prevalent in surgical patients and leads to comorbidities and a poorer postoperative course. There are no studies that compare the clinical outcomes of implementing a nutrition screening tool in surgical patients with standard clinica...

  • Review
  • Open Access
145 Citations
22,041 Views
22 Pages

From Probiotics to Psychobiotics: Live Beneficial Bacteria Which Act on the Brain-Gut Axis

  • Luis G. Bermúdez-Humarán,
  • Eva Salinas,
  • Genaro G. Ortiz,
  • Luis J. Ramirez-Jirano,
  • J. Alejandro Morales and
  • Oscar K. Bitzer-Quintero

20 April 2019

There is an important relationship between probiotics, psychobiotics and cognitive and behavioral processes, which include neurological, metabolic, hormonal and immunological signaling pathways; the alteration in these systems may cause alterations i...

  • Article
  • Open Access
44 Citations
10,051 Views
17 Pages

Theobromine Improves Working Memory by Activating the CaMKII/CREB/BDNF Pathway in Rats

  • Rafiad Islam,
  • Kentaro Matsuzaki,
  • Eri Sumiyoshi,
  • Md Emon Hossain,
  • Michio Hashimoto,
  • Masanori Katakura,
  • Naotoshi Sugimoto and
  • Osamu Shido

20 April 2019

Theobromine (TB) is a primary methylxanthine found in cacao beans. cAMP-response element-binding protein (CREB) is a transcription factor, which is involved in different brain processes that bring about cellular changes in response to discrete sets o...

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Nutrients - ISSN 2072-6643