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Nutrients, Volume 9, Issue 3

2017 March - 134 articles

Cover Story: Diet is one of the largest modifiable risk factors for chronic kidney disease (CKD)-related death and disability. CKD is largely a progressive disease; however, it is increasingly appreciated that hallmarks of chronic kidney disease such as albuminuria can regress over time. Since albuminuria is a strong risk factor for GFR loss, modifiable lifestyle factors that lead to an improvement in albuminuria would likely reduce the burden of CKD in high-risk individuals, such as patients with diabetes. This review focuses on the role of diet in the pathogenesis and progression of CKD and discusses the latest findings related to the mechanisms of diet-induced kidney disease. It is possible that optimizing diet quality or restricting dietary intake could be harnessed as an adjunct therapy for CKD prevention or progression in susceptible individuals, thereby reducing the burden of CKD. View the paper
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Articles (134)

  • Article
  • Open Access
61 Citations
11,042 Views
17 Pages

Reported Energy Intake Accuracy Compared to Doubly Labeled Water and Usability of the Mobile Food Record among Community Dwelling Adults

  • Carol J. Boushey,
  • Melissa Spoden,
  • Edward J. Delp,
  • Fengqing Zhu,
  • Marc Bosch,
  • Ziad Ahmad,
  • Yurii B. Shvetsov,
  • James P. DeLany and
  • Deborah A. Kerr

22 March 2017

The mobile Food Record (mFR) is an image-based dietary assessment method for mobile devices. The study primary aim was to test the accuracy of the mFR by comparing reported energy intake (rEI) to total energy expenditure (TEE) using the doubly labele...

  • Article
  • Open Access
87 Citations
38,656 Views
10 Pages

Beetroot Juice Supplementation Improves High-Intensity Intermittent Type Exercise Performance in Trained Soccer Players

  • Jean Nyakayiru,
  • Kristin L. Jonvik,
  • Jorn Trommelen,
  • Philippe J. M. Pinckaers,
  • Joan M. Senden,
  • Luc J. C. Van Loon and
  • Lex B. Verdijk

22 March 2017

It has been shown that nitrate supplementation can enhance endurance exercise performance. Recent work suggests that nitrate ingestion can also increase intermittent type exercise performance in recreational athletes. We hypothesized that six days of...

  • Article
  • Open Access
41 Citations
7,676 Views
12 Pages

Prevalence and Determinants of Suboptimal Vitamin D Levels in a Multiethnic Asian Population

  • Ryan Eyn Kidd Man,
  • Ling-Jun Li,
  • Ching-Yu Cheng,
  • Tien Yin Wong,
  • Ecosse Lamoureux and
  • Charumathi Sabanayagam

22 March 2017

This population-based cross-sectional study examined the prevalence and risk factors of suboptimal vitamin D levels (assessed using circulating 25-hydroxycholecalciferol (25(OH)D)) in a multi-ethnic sample of Asian adults. Plasma 25(OH)D concentratio...

  • Review
  • Open Access
53 Citations
12,511 Views
11 Pages

22 March 2017

Previous systematic reviews and meta-analyses have evaluated the association of dairy consumption and the risk of cardiovascular disease (CVD). However, the findings were inconsistent. No quantitative analysis has specifically assessed the effect of...

  • Article
  • Open Access
77 Citations
8,591 Views
10 Pages

Reference Values of 14 Serum Trace Elements for Pregnant Chinese Women: A Cross-Sectional Study in the China Nutrition and Health Survey 2010–2012

  • Xiaobing Liu,
  • Yu Zhang,
  • Jianhua Piao,
  • Deqian Mao,
  • Yajie Li,
  • Weidong Li,
  • Lichen Yang and
  • Xiaoguang Yang

21 March 2017

The development of reference values of trace elements is recognized as a fundamental prerequisite for the assessment of trace element nutritional status and health risks. In this study, a total of 1400 pregnant women aged 27.0 ± 4.5 years were random...

  • Review
  • Open Access
76 Citations
14,152 Views
16 Pages

Dietary Protein and Amino Acid Supplementation in Inflammatory Bowel Disease Course: What Impact on the Colonic Mucosa?

  • Sandra Vidal-Lletjós,
  • Martin Beaumont,
  • Daniel Tomé,
  • Robert Benamouzig,
  • François Blachier and
  • Annaïg Lan

21 March 2017

Inflammatory bowel diseases (IBD), after disease onset, typically progress in two cyclically repeated phases, namely inflammatory flare and remission, with possible nutritional status impairment. Some evidence, either from epidemiological, clinical,...

  • Article
  • Open Access
16 Citations
7,369 Views
9 Pages

Serum Amyloid A Production Is Triggered by Sleep Deprivation in Mice and Humans: Is That the Link between Sleep Loss and Associated Comorbidities?

  • Edson M. De Oliveira,
  • Bruna Visniauskas,
  • Sergio Tufik,
  • Monica L. Andersen,
  • Jair R. Chagas and
  • Ana Campa

21 March 2017

Serum amyloid A (SAA) was recently associated with metabolic endotoxemia, obesity and insulin resistance. Concurrently, insufficient sleep adversely affects metabolic health and is an independent predisposing factor for obesity and insulin resistance...

  • Review
  • Open Access
122 Citations
22,828 Views
18 Pages

Hydroxytyrosol in the Prevention of the Metabolic Syndrome and Related Disorders

  • Julien Peyrol,
  • Catherine Riva and
  • Marie Josèphe Amiot

20 March 2017

Virgin olive oil (VOO) constitutes the main source of fat in the Mediterranean diet. VOO is rich in oleic acid, displaying health-promoting properties, but also contains minor bioactive components, especially phenolic compounds. Hydroxytyrosol (HT),...

  • Article
  • Open Access
110 Citations
12,861 Views
12 Pages

20 March 2017

Emerging evidence from in vivo and in vitro studies have shown that vitamin D may play an important role in the development of diabetic retinopathy (DR), but individually published studies showed inconclusive results. The aim of this study was to qua...

  • Article
  • Open Access
17 Citations
13,961 Views
11 Pages

Oral Cyanocobalamin is Effective in the Treatment of Vitamin B12 Deficiency in Crohn’s Disease

  • Fernando Gomollón,
  • Carla J. Gargallo,
  • Jose Fernando Muñoz,
  • Raquel Vicente,
  • Alberto Lue,
  • Alberto Mir,
  • Marta García-Alvarado,
  • Marta Gracia and
  • Santiago García-López

20 March 2017

Cobalamin deficiency is common in patients with Crohn’s disease (CD). Intramuscular cobalamin continues to be the standard therapy for the deficiency and maintenance treatment in these patients, although oral route has been demonstrated to be effecti...

  • Article
  • Open Access
76 Citations
9,179 Views
10 Pages

Intra Amniotic Administration of Raffinose and Stachyose Affects the Intestinal Brush Border Functionality and Alters Gut Microflora Populations

  • Sarina Pacifici,
  • Jaehong Song,
  • Cathy Zhang,
  • Qiaoye Wang,
  • Raymond P. Glahn,
  • Nikolai Kolba and
  • Elad Tako

19 March 2017

This study investigates the effectiveness of two types of prebiotics—stachyose and raffinose—which are present in staple food crops that are widely consumed in regions where dietary Fe deficiency is a health concern. The hypothesis is that these preb...

  • Article
  • Open Access
7 Citations
7,940 Views
9 Pages

Effects of the Mediterranean Diet before and after Weight Loss on Eating Behavioral Traits in Men with Metabolic Syndrome

  • Élise Carbonneau,
  • Marie-Michelle Royer,
  • Caroline Richard,
  • Patrick Couture,
  • Sophie Desroches,
  • Simone Lemieux and
  • Benoît Lamarche

19 March 2017

The objective of this study was to investigate the impact of the Mediterranean diet (MedDiet) consumed before and after weight loss on eating behavioral traits as measured by the Three-Factor Eating Questionnaire (TFEQ) in men with metabolic syndrome...

  • Article
  • Open Access
14 Citations
7,281 Views
11 Pages

A Specific Mixture of Nutrients Suppresses Ovarian Cancer A-2780 Tumor Incidence, Growth, and Metastasis to Lungs

  • Mohd Waheed Roomi,
  • Tatiana Kalinovsky,
  • Matthias Rath and
  • Aleksandra Niedzwiecki

18 March 2017

Ovarian cancer is the deadliest gynecological malignancy in women, and fifth leading cause of death. Despite advances made in chemotherapy and surgery, the average time of clinical remission is approximately 2 years and the 5-year survival rate is 45...

  • Article
  • Open Access
6 Citations
7,037 Views
12 Pages

Inhibition of Neoplastic Transformation and Chemically-Induced Skin Hyperplasia in Mice by Traditional Chinese Medicinal Formula Si-Wu-Tang

  • Mandy M. Liu,
  • Kevin M. Huang,
  • Steven Yeung,
  • Andy Chang,
  • Suhui Zhang,
  • Nan Mei,
  • Cyrus Parsa,
  • Robert Orlando and
  • Ying Huang

18 March 2017

Exploring traditional medicines may lead to the development of low-cost and non-toxic cancer preventive agents. Si-Wu-Tang (SWT), comprising the combination of four herbs, Rehmanniae, Angelica, Chuanxiong, and Paeoniae, is one of the most popular tra...

  • Review
  • Open Access
45 Citations
8,346 Views
14 Pages

Association between Circulating Vitamin D Level and Urolithiasis: A Systematic Review and Meta-Analysis

  • Henglong Hu,
  • Jiaqiao Zhang,
  • Yuchao Lu,
  • Zongbiao Zhang,
  • Baolong Qin,
  • Hongbin Gao,
  • Yufeng Wang,
  • Jianning Zhu,
  • Qing Wang and
  • Shaogang Wang
  • + 2 authors

18 March 2017

Many studies compared the serum/plasma 1,25 dihydroxyvitamin D3 (1,25(OH)2D) and 25 hydroxyvitamin D3 (25(OH)D) between people with and without nephrolithiasis, and their results were conflicting. After systematically searching PubMed, Web of Science...

  • Article
  • Open Access
29 Citations
6,965 Views
11 Pages

Lactational Stage of Pasteurized Human Donor Milk Contributes to Nutrient Limitations for Infants

  • Christina J. Valentine,
  • Georgia Morrow,
  • Amanda Reisinger,
  • Kelly A. Dingess,
  • Ardythe L. Morrow and
  • Lynette K. Rogers

18 March 2017

Background. Mother’s own milk is the first choice for feeding preterm infants, but when not available, pasteurized human donor milk (PDM) is often used. Infants fed PDM have difficulties maintaining appropriate growth velocities. To assess the most b...

  • Article
  • Open Access
27 Citations
8,224 Views
10 Pages

Inverse Association of Plasma Chromium Levels with Newly Diagnosed Type 2 Diabetes: A Case-Control Study

  • Sijing Chen,
  • Xiaoling Jin,
  • Zhilei Shan,
  • Shuzhen Li,
  • Jiawei Yin,
  • Taoping Sun,
  • Cheng Luo,
  • Wei Yang,
  • Ping Yao and
  • Liegang Liu
  • + 5 authors

17 March 2017

Chromium has long been known as an enhancer of insulin action. However, the role of chromium in the development of type 2 diabetes mellitus (T2DM) in humans remains controversial. The current study aimed to examine the associations of plasma chromium...

  • Review
  • Open Access
78 Citations
17,468 Views
19 Pages

17 March 2017

Depression is a complex disorder influenced by a variety of biological and environmental factors. Due to significant heterogeneity, there are remarkable differences in how patients respond to treatment. A primary objective of psychiatric research is...

  • Article
  • Open Access
55 Citations
10,256 Views
13 Pages

17 March 2017

Total serum magnesium (Mg) concentration (SMC) is commonly used to assess Mg status. This study reports current SMCs of Canadians and their associations with demographic factors, diabetes, and measures of glycemic control and insulin resistance using...

  • Review
  • Open Access
72 Citations
14,768 Views
18 Pages

17 March 2017

Recurrent binge eating episodes, the core feature of Bulimia Nervosa (BN) and Binge Eating Disorder (BED), are frequently comorbid with obesity. Psychological interventions, notably Cognitive Behavioural Therapy (CBT), are effective for binge eating...

  • Article
  • Open Access
25 Citations
8,771 Views
13 Pages

Consumption of Fruit or Fiber-Fruit Decreases the Risk of Cardiovascular Disease in a Mediterranean Young Cohort

  • Pilar Buil-Cosiales,
  • Miguel Angel Martinez-Gonzalez,
  • Miguel Ruiz-Canela,
  • Javier Díez-Espino,
  • Ana García-Arellano and
  • Estefania Toledo

17 March 2017

Fiber and fiber-rich foods have been inversely associated with cardiovascular disease (CVD), but the evidence is scarce in young and Mediterranean cohorts. We used Cox regression models to assess the association between quintiles of total fiber and f...

  • Article
  • Open Access
60 Citations
11,354 Views
11 Pages

17 March 2017

Design: Functional foods may be useful for people with diabetes. The soluble fibers beta glucans can modify starch digestion and improve postprandial glucose response. We analyzed the metabolic effects of a specifically designed ‘functional’ bread, l...

  • Article
  • Open Access
25 Citations
8,361 Views
8 Pages

Analysis of Outcomes of the NRS 2002 in Patients Hospitalized in Nephrology Wards

  • Paulina Borek,
  • Michał Chmielewski,
  • Sylwia Małgorzewicz and
  • Alicja Dębska Ślizień

16 March 2017

Introduction: Malnutrition is a common problem among hospitalized patients. In chronic kidney disease, it affects up to 50% of the population. Undernourishment has an adverse effect on prognosis and prolongs convalescence. The aim of the study was to...

  • Review
  • Open Access
141 Citations
107,709 Views
21 Pages

Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement

  • Matthew Butawan,
  • Rodney L. Benjamin and
  • Richard J. Bloomer

16 March 2017

Methylsulfonylmethane (MSM) has become a popular dietary supplement used for a variety of purposes, including its most common use as an anti-inflammatory agent. It has been well-investigated in animal models, as well as in human clinical trials and e...

  • Discussion
  • Open Access
65 Citations
13,190 Views
15 Pages

16 March 2017

An increasing number of low-income countries (LICs) exhibit high rates of malnutrition coincident with rising rates of overweight and obesity. Individual-level dietary data are needed to inform effective responses, yet dietary data from large-scale s...

  • Article
  • Open Access
13 Citations
6,505 Views
19 Pages

Transglycosylated Starch Improves Insulin Response and Alters Lipid and Amino Acid Metabolome in a Growing Pig Model

  • Monica A. Newman,
  • Qendrim Zebeli,
  • Eva Eberspächer,
  • Dietmar Grüll,
  • Timea Molnar and
  • Barbara U. Metzler-Zebeli

16 March 2017

Due to the functional properties and physiological effects often associated with chemically modified starches, significant interest lies in their development for incorporation in processed foods. This study investigated the effect of transglycosylate...

  • Review
  • Open Access
88 Citations
22,646 Views
9 Pages

The Low FODMAP Diet: Many Question Marks for a Catchy Acronym

  • Giulia Catassi,
  • Elena Lionetti,
  • Simona Gatti and
  • Carlo Catassi

16 March 2017

FODMAP, “Fermentable Oligo-, Di- and Mono-saccharides And Polyols”, is a heterogeneous group of highly fermentable but poorly absorbed short-chain carbohydrates and polyols. Dietary FODMAPs might exacerbate intestinal symptoms by increasing small int...

  • Article
  • Open Access
93 Citations
10,148 Views
10 Pages

Hypocholesterolemic Effects of Probiotic Mixture on Diet-Induced Hypercholesterolemic Rats

  • Shang-Jin Kim,
  • Sang Hoon Park,
  • Hong-Sig Sin,
  • Seung-Hwan Jang,
  • Sang-Wang Lee,
  • Seon-Young Kim,
  • Bora Kwon,
  • Kang-Yeol Yu,
  • Su Young Kim and
  • Dong Kwon Yang

16 March 2017

Growing evidence has indicated that supplementation with probiotics improves lipid metabolism. We aimed to investigate the beneficial effects of a probiotics mixture (PM) of three strains belonging to the species Bifidobacterium (B. longum, B. lactis...

  • Article
  • Open Access
63 Citations
8,612 Views

Protective Effect of Protocatechuic Acid on TNBS-Induced Colitis in Mice Is Associated with Modulation of the SphK/S1P Signaling Pathway

  • Irene Crespo,
  • Beatriz San-Miguel,
  • José Luis Mauriz,
  • Juan José Ortiz de Urbina,
  • Mar Almar,
  • María Jesús Tuñón and
  • Javier González-Gallego

16 March 2017

(1) Background: The present study aimed to investigate whether beneficial effects of protocatechuic acid (PCA) are associated with inhibition of the SphK/S1P axis and related signaling pathways in a 2,4,6-trinitrobenzenesulfonic acid (TNBS) model of...

  • Article
  • Open Access
8 Citations
6,242 Views
15 Pages

The Addition of Liquid Fructose to a Western-Type Diet in LDL-R−/− Mice Induces Liver Inflammation and Fibrogenesis Markers without Disrupting Insulin Receptor Signalling after an Insulin Challenge

  • Gemma Sangüesa,
  • Miguel Baena,
  • Natalia Hutter,
  • José Carlos Montañés,
  • Rosa María Sánchez,
  • Núria Roglans,
  • Juan Carlos Laguna and
  • Marta Alegret

15 March 2017

A high consumption of fat and simple sugars, especially fructose, has been related to the development of insulin resistance, but the mechanisms involved in the effects of these nutrients are not fully understood. This study investigates the effects o...

  • Article
  • Open Access
77 Citations
11,040 Views
13 Pages

Differences in Dietary Preferences, Personality and Mental Health in Australian Adults with and without Food Addiction

  • Tracy Burrows,
  • Leanne Hides,
  • Robyn Brown,
  • Christopher V Dayas and
  • Frances Kay-Lambkin

15 March 2017

Increased obesity rates, an evolving food supply and the overconsumption of energy dense foods has led to an increase in research exploring addictive eating behaviours. This study aimed to investigate food addiction in a sample of Australian adults u...

  • Article
  • Open Access
31 Citations
8,595 Views
15 Pages

15 March 2017

Hypercholesterolemia is a known risk factor for cardiovascular diseases and affects a high proportion of the population. This study aimed to assess and compare the determinants of hypercholesterolemia among Chinese adults aged 18 years and above, fro...

  • Review
  • Open Access
27 Citations
7,576 Views
13 Pages

15 March 2017

Pancreatic cancer is the fourth most common cause of cancer-related deaths with a dismal average five-year survival rate of six percent. Substitutional progress has been made in understanding how pancreatic cancer develops and progresses. Evidence is...

  • Review
  • Open Access
26 Citations
11,165 Views
15 Pages

Potential Impact of Diet on Treatment Effect from Anti-TNF Drugs in Inflammatory Bowel Disease

  • Vibeke Andersen,
  • Axel Kornerup Hansen and
  • Berit Lilienthal Heitmann

15 March 2017

We wanted to investigate the current knowledge on the impact of diet on anti-TNF response in inflammatory bowel diseases (IBD), to identify dietary factors that warrant further investigations in relation to anti-TNF treatment response, and, finally,...

  • Review
  • Open Access
91 Citations
11,525 Views
8 Pages

Vitamins and Microelement Bioavailability in Different Stages of Chronic Kidney Disease

  • Magdalena Jankowska,
  • Bolesław Rutkowski and
  • Alicja Dębska-Ślizień

15 March 2017

Chronic kidney disease (CKD) predisposes one to either deficiency or toxic excess of different micronutrients. The knowledge on micronutrients—specifically water-soluble vitamins and trace elements—in CKD is very limited. Consequently, current guidel...

  • Article
  • Open Access
123 Citations
20,384 Views
17 Pages

Effects of a Diet-Based Weight-Reducing Program with Probiotic Supplementation on Satiety Efficiency, Eating Behaviour Traits, and Psychosocial Behaviours in Obese Individuals

  • Marina Sanchez,
  • Christian Darimont,
  • Shirin Panahi,
  • Vicky Drapeau,
  • André Marette,
  • Valerie H. Taylor,
  • Jean Doré and
  • Angelo Tremblay

15 March 2017

This study evaluated the impact of probiotic supplementation (Lactobacillus rhamnosus CGMCC1.3724 (LPR)) on appetite sensations and eating behaviors in the context of a weight-reducing program. Obese men (n = 45) and women (n = 60) participated in a...

  • Editorial
  • Open Access
2 Citations
5,342 Views
4 Pages

15 March 2017

It is usually acknowledged that high-dose vitamin A supplementation (VAS) provides no sustained improvement in vitamin A status, and that the effect of VAS on mortality is more likely linked to its immunomodulating effects. Nonetheless, it is widely...

  • Case Report
  • Open Access
18 Citations
9,813 Views
5 Pages

15 March 2017

Vitamin B12 (B12) deficiency is known to be associated with various neurological manifestations. Although central manifestations such as dementia or subacute combined degeneration are the most classic, neurological manifestations also include sensory...

  • Article
  • Open Access
75 Citations
14,454 Views
12 Pages

14 March 2017

Background: To address nutrition-related population mental health data gaps, we examined relationships among food insecurity, diet quality, and perceived mental health. Methods: Stratified and logistic regression analyses of respondents aged 19–70 ye...

  • Article
  • Open Access
57 Citations
12,585 Views
15 Pages

Association between Coffee Consumption and Its Polyphenols with Cardiovascular Risk Factors: A Population-Based Study

  • Andreia Machado Miranda,
  • Josiane Steluti,
  • Regina Mara Fisberg and
  • Dirce Maria Marchioni

14 March 2017

Epidemiological studies have examined the effect of coffee intake on cardiovascular disease, but the benefits and risks for the cardiovascular system remain controversial. Our objective was to evaluate the association between coffee consumption and i...

  • Article
  • Open Access
28 Citations
7,025 Views
9 Pages

14 March 2017

Iron is essential for providing oxygen to working muscles during exercise, and iron deficiency leads to decreased exercise capacity during endurance events. However, the mechanism of iron deficiency among endurance athletes remains unclear. In this s...

  • Article
  • Open Access
60 Citations
14,307 Views
22 Pages

Dietary Intake of Individual (Free and Intrinsic) Sugars and Food Sources in the Spanish Population: Findings from the ANIBES Study

  • Emma Ruiz,
  • Paula Rodriguez,
  • Teresa Valero,
  • José M. Ávila,
  • Javier Aranceta-Bartrina,
  • Ángel Gil,
  • Marcela González-Gross,
  • Rosa M. Ortega,
  • Lluis Serra-Majem and
  • Gregorio Varela-Moreiras

14 March 2017

The consumption of total and individual sugars is controversial and little is known about consumption and dietary sources in Spain. The purpose was to examine free and intrinsic sugar intake and food and beverage sources. The ANIBES Study (Anthropome...

  • Article
  • Open Access
52 Citations
8,960 Views
18 Pages

13 March 2017

Data on beverage consumption patterns in early life are limited. The aim of this study was to describe beverage consumption by sociodemographic characteristics, along with water intake and sources of water among U.S. children aged 0–24 months. Data f...

  • Article
  • Open Access
17 Citations
5,972 Views
15 Pages

Bioavailability of Microencapsulated Iron from Fortified Bread Assessed Using Piglet Model

  • Malgorzata A. Bryszewska,
  • Luca Laghi,
  • Augusta Zannoni,
  • Andrea Gianotti,
  • Francesca Barone,
  • Danielle L. Taneyo Saa,
  • Maria L. Bacci,
  • Domenico Ventrella and
  • Monica Forni

13 March 2017

The aim of this study was to investigate the influence of oral iron supplementation, in the form of fortified breads, on the growth performance, health, iron status parameters, and fecal metabolome of anemic piglets. A study was conducted on 24 hybri...

  • Article
  • Open Access
17 Citations
7,356 Views
11 Pages

Feasibility of Assessing Diet with a Mobile Food  Record for Adolescents and Young Adults with  Down Syndrome

  • Katherine E. Bathgate,
  • Jill L. Sherriff,
  • Helen Leonard,
  • Satvinder S. Dhaliwal,
  • Edward J. Delp,
  • Carol J. Boushey and
  • Deborah A. Kerr

13 March 2017

Technology‐based methods for assessing diet in those with disability remains largely unexplored. The aim was to assess the feasibility of assessing diet with an image‐based mobile food record application (mFR) in 51 adolescents and young adults with...

  • Article
  • Open Access
64 Citations
7,917 Views
13 Pages

A Combination of Flaxseed Oil and Astaxanthin Improves Hepatic Lipid Accumulation and Reduces Oxidative Stress in High Fat-Diet Fed Rats

  • Jiqu Xu,
  • Shuang Rong,
  • Hui Gao,
  • Chang Chen,
  • Wei Yang,
  • Qianchun Deng,
  • Qingde Huang,
  • Lingyun Xiao and
  • Fenghong Huang

13 March 2017

Hepatic lipid accumulation and oxidative stress are crucial pathophysiological mechanisms for non-alcoholic fatty liver disease (NAFLD). Thus, we examined the effect of a combination of flaxseed oil (FO) and astaxanthin (ASX) on hepatic lipid accumul...

  • Article
  • Open Access
29 Citations
8,292 Views
10 Pages

Correlations between Maternal, Breast Milk, and Infant Vitamin B12 Concentrations among Mother–Infant Dyads in Vancouver, Canada and Prey Veng, Cambodia: An Exploratory Analysis

  • Philip Chebaya,
  • Crystal D. Karakochuk,
  • Kaitlin M. March,
  • Nancy N. Chen,
  • Rosemary A. Stamm,
  • Hou Kroeun,
  • Prak Sophonneary,
  • Mam Borath,
  • Setareh Shahab-Ferdows and
  • Kyly C. Whitfield
  • + 6 authors

12 March 2017

Vitamin B12 plays an essential role in fetal and infant development. In regions where animal source food consumption is low and perinatal supplementation is uncommon, infants are at risk of vitamin B12 deficiency. In this secondary analysis, we measu...

  • Article
  • Open Access
33 Citations
8,079 Views
17 Pages

11 March 2017

There is increasing evidence linking early life adiposity to disease risk later in life. This study aims at determining the prevalence and correlates of overweight and obesity among preschoolers in Lebanon. A national cross-sectional survey was condu...

  • Review
  • Open Access
47 Citations
25,559 Views
29 Pages

Stirring the Pot: Can Dietary Modification Alleviate the Burden of CKD?

  • Matthew Snelson,
  • Rachel E. Clarke and
  • Melinda T. Coughlan

11 March 2017

Diet is one of the largest modifiable risk factors for chronic kidney disease (CKD)-related death and disability. CKD is largely a progressive disease; however, it is increasingly appreciated that hallmarks of chronic kidney disease such as albuminur...

  • Article
  • Open Access
104 Citations
10,453 Views
11 Pages

Absorption, Metabolism and Excretion of Cranberry (Poly)phenols in Humans: A Dose Response Study and Assessment of Inter-Individual Variability

  • Rodrigo P. Feliciano,
  • Charlotte E. Mills,
  • Geoffrey Istas,
  • Christian Heiss and
  • Ana Rodriguez-Mateos

11 March 2017

The beneficial health effects of cranberries have been attributed to their (poly)phenol content. Recent studies have investigated the absorption, metabolism and excretion of cranberry (poly)phenols; however, little is known about whether they follow...

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Nutrients - ISSN 2072-6643