Skip Content
You are currently on the new version of our website. Access the old version .

Micromachines, Volume 10, Issue 12

2019 December - 93 articles

Cover Story: Flexible microfluidics is an emerging research area that will potentially bring a step change into chemistry, electronics, biology, and medicine. Large deformation of microchannels and strong fluid–structure interactions are examples of the distinct features of flexibility that may change the way microfluidic functions are implemented. A novel use of flexibility will allow unique solutions for valving, pumping, mixing, and separation. This paper discusses the fundamentals, materials, applications, and future perspectives of this exciting research area. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (93)

  • Article
  • Open Access
6 Citations
4,235 Views
11 Pages

17 December 2019

Seed germination and seedling root development are important indicators of plant development. This work designed and fabricated a foldable microfluidic chip array for conducting nondestructive and continuous evaluation of seed germination and subsequ...

  • Article
  • Open Access
12 Citations
4,579 Views
13 Pages

17 December 2019

Along with the great performance in diagnosing cardiovascular diseases, current stethoscopes perform unsatisfactorily in controlling undesired noise caused by the surrounding environment and detector operation. In this case, a low-noise-level heart s...

  • Feature Paper
  • Concept Paper
  • Open Access
27 Citations
5,029 Views
12 Pages

17 December 2019

The majority of commercially oriented microfluidic technologies provide novel point-of-use solutions for laboratory automation with important areas in the context of the life sciences such as health care, biopharma, veterinary medicine and agrifood a...

  • Article
  • Open Access
7 Citations
4,497 Views
10 Pages

Experimental Study on Three-Dimensional Microstructure Copper Electroforming Based on 3D Printing Technology

  • Yuanyuan Wu,
  • Shuangqing Qian,
  • Hua Zhang,
  • Yong Zhang,
  • Hongbei Cao and
  • Mingyu Huang

17 December 2019

In order to fabricate three-dimensional metal microstructures, a combined machining process based on 3D printing technology and electroforming technology is proposed. Firstly, a substrate with microstructures is fabricated by 3D printing technology,...

  • Article
  • Open Access
8 Citations
3,857 Views
12 Pages

Local Acoustic Fields Powered Assembly of Microparticles and Applications

  • Hui Shen,
  • Kangdong Zhao,
  • Zhiwen Wang,
  • Xiaoyu Xu,
  • Jiayu Lu,
  • Wenjuan Liu and
  • Xiaolong Lu

16 December 2019

Controllable assembly in nano-/microscale holds considerable promise for bioengineering, intracellular manipulation, diagnostic sensing, and biomedical applications. However, up to now, micro-/nanoscopic assembly methods are severely limited by the f...

  • Feature Paper
  • Article
  • Open Access
15 Citations
5,334 Views
12 Pages

Microfluidic Array Chip for Parallel Detection of Waterborne Bacteria

  • Lena Gorgannezhad,
  • Kamalalayam Rajan Sreejith,
  • Jun Zhang,
  • Gregor Kijanka,
  • Melody Christie,
  • Helen Stratton and
  • Nam-Trung Nguyen

16 December 2019

The polymerase chain reaction (PCR) is a robust technique used to make multiple copies of a segment of DNA. However, the available PCR platforms require elaborate and time-consuming operations or costly instruments, hindering their application. Herei...

  • Article
  • Open Access
13 Citations
5,009 Views
14 Pages

Electroosmotic Flow Behavior of Viscoelastic LPTT Fluid in a Microchannel

  • Dilin Chen,
  • Jie Li,
  • Haiwen Chen,
  • Lai Zhang,
  • Hongna Zhang and
  • Yu Ma

15 December 2019

In many research works, the fluid medium in electroosmosis is considered to be a Newtonian fluid, while the polymer solutions and biological fluids used in biomedical fields mostly belong to the non-Newtonian category. Based on the finite volume meth...

  • Article
  • Open Access
37 Citations
11,222 Views
11 Pages

Wireless, Skin-Mountable EMG Sensor for Human–Machine Interface Application

  • Min-Su Song,
  • Sung-Gu Kang,
  • Kyu-Tae Lee and
  • Jeonghyun Kim

14 December 2019

The development of advanced technologies for wireless data collection and the analysis of quantitative data, with application to a human–machine interface (HMI), is of growing interest. In particular, various wearable devices related to HMIs ar...

  • Article
  • Open Access
12 Citations
4,093 Views
11 Pages

14 December 2019

To perform zebrafish larvae-related experiments within a microfluidic environment, the larvae need to be anesthetized and subsequently transported into respective test sections through mechanical or manual means. However, anesthetization tends to aff...

  • Article
  • Open Access
11 Citations
4,198 Views
10 Pages

13 December 2019

Herein, the optical field distribution and electrical property improvements of the InGaN laser diode with an emission wavelength around 416 nm are theoretically investigated by adjusting the relative thickness of the first or last barrier layer in th...

  • Article
  • Open Access
10 Citations
4,094 Views
8 Pages

13 December 2019

Quantifiable sensing of common microbes in chronic wounds has the potential to enable an objective assessment of wound healing for diagnostic applications. Sensing platforms should be robust, simple, and flexible to provide clinicians with a point-of...

  • Article
  • Open Access
25 Citations
6,997 Views
10 Pages

Study on a High Performance MEMS Infrared Thermopile Detector

  • Aida Bao,
  • Cheng Lei,
  • Haiyang Mao,
  • Ruirui Li and
  • Yihao Guan

13 December 2019

This paper presents a high-performance micro-electromechanical systems (MEMS) thermopile infrared detector. It consists of a double-end beam and a dual-layer thermocouple structure, which improves the responsivity of the detector. The etch-stop struc...

  • Article
  • Open Access
6 Citations
3,046 Views
11 Pages

13 December 2019

Measuring temperature and moisture are important in many scenarios. It has been verified that temperature greatly affects the accuracy of moisture sensing. Moisture sensing performance would suffer without temperature calibrations. This paper introdu...

  • Article
  • Open Access
5 Citations
3,386 Views
15 Pages

Investigation of the Pd Nanoparticles-Assisted Chemical Etching of Silicon for Ethanol Solution Electrooxidation

  • Olga Volovlikova,
  • Gennady Silakov,
  • Sergey Gavrilov,
  • Tomasz Maniecki and
  • Alexander Dudin

12 December 2019

The formation of porous silicon by Pd nanoparticles-assisted chemical etching of single-crystal Si with resistivity ρ = 0.01 Ω·cm at 25 °C, 50 °C and 75 °C in HF/H2O2/H2O solution was studied. Porous layers of silicon wer...

  • Article
  • Open Access
2 Citations
3,034 Views
27 Pages

12 December 2019

In this paper, an approach is proposed for the simultaneous manipulation of multiple hexagonal and square plastic–glass type microparts that are positioned randomly on a smart platform (SP) using electrostatic forces applied by the suitable act...

  • Feature Paper
  • Article
  • Open Access
13 Citations
5,188 Views
13 Pages

12 December 2019

Microfluidics is facing critical challenges in the quest of miniaturizing, integrating, and automating in vitro diagnostics, including the increasing complexity of assays, the gap between the macroscale world and the microscale devices, and the diver...

  • Article
  • Open Access
19 Citations
4,801 Views
11 Pages

Microfluidic Reactors for Plasmonic Photocatalysis Using Gold Nanoparticles

  • Huaping Jia,
  • Yat Lam Wong,
  • Aoqun Jian,
  • Chi Chung Tsoi,
  • Meiling Wang,
  • Wanghao Li,
  • Wendong Zhang,
  • Shengbo Sang and
  • Xuming Zhang

11 December 2019

This work reports a microfluidic reactor that utilizes gold nanoparticles (AuNPs) for the highly efficient photocatalytic degradation of organic pollutants under visible light. The bottom of microchamber has a TiO2 film covering a layer of AuNPs (nam...

  • Article
  • Open Access
1 Citations
3,348 Views
11 Pages

11 December 2019

Micromechanically exfoliating graphene on S i / S i O 2 substrates is commonplace for graphene researchers, but locating actual graphene flakes on these substrates is a high-effort and tiresome task. The main purpose of this work was...

  • Article
  • Open Access
10 Citations
4,358 Views
9 Pages

A Microfluidic Detection System for Bladder Cancer Tumor Cells

  • Shuxing Lv,
  • Jinwei Yu,
  • Yan Zhao,
  • Hongxiang Li,
  • Fang Zheng,
  • Ning Liu,
  • Dahua Li and
  • Xuguo Sun

11 December 2019

The clinical characteristics of excreted tumor cells can be found in the urine of bladder cancer patients, meaning the identification of tumor cells in urine can assist in bladder cancer diagnosis. The presence of white blood cells and epithelial cel...

  • Article
  • Open Access
15 Citations
5,152 Views
11 Pages

µ-PIV Measurements of Flows Generated by Photolithography-Fabricated Achiral Microswimmers

  • Liyuan Tan,
  • Jamel Ali,
  • U Kei Cheang,
  • Xiangcheng Shi,
  • Dalhyung Kim and
  • Min Jun Kim

10 December 2019

Robotic micro/nanoswimmers can potentially be used as tools for medical applications, such as drug delivery and noninvasive surgery. Recently, achiral microswimmers have gained significant attention because of their simple structures, which enables h...

  • Article
  • Open Access
25 Citations
4,679 Views
13 Pages

Multifunctional Textile Platform for Fiber Optic Wearable Temperature-Monitoring Application

  • Ziyang Xiang,
  • Liuwei Wan,
  • Zidan Gong,
  • Zhuxin Zhou,
  • Zhengyi Ma,
  • Xia OuYang,
  • Zijian He and
  • Chi Chiu Chan

10 December 2019

Wearable sensing technologies have been developed rapidly in the last decades for physiological and biomechanical signal monitoring. Much attention has been paid to functions of wearable applications, but comfort parameters have been overlooked. This...

  • Article
  • Open Access
27 Citations
4,836 Views
12 Pages

10 December 2019

Although enzymatic microbioreactors have recently gained lots of attention, reports on the use of whole cells as biocatalysts in microreactors have been rather modest. In this work, an efficient microreactor with permeabilized Saccharomyces cerevisia...

  • Feature Paper
  • Article
  • Open Access
22 Citations
4,630 Views
9 Pages

Passive Wireless Pressure Sensing for Gastric Manometry

  • Alexander Benken and
  • Yogesh Gianchandani

10 December 2019

We describe a wireless microsystem for gastrointestinal manometry that couples a microfabricated capacitive transducer to a dual-axis inductor, forming a resonant inductor-capacitor (LC) sensor within an ingestible 3D printed biocompatible capsule me...

  • Feature Paper
  • Article
  • Open Access
8 Citations
7,201 Views
9 Pages

Design and Fabrication of Flexible Naked-Eye 3D Display Film Element Based on Microstructure

  • Axiu Cao,
  • Li Xue,
  • Yingfei Pang,
  • Liwei Liu,
  • Hui Pang,
  • Lifang Shi and
  • Qiling Deng

9 December 2019

The naked-eye three-dimensional (3D) display technology without wearing equipment is an inevitable future development trend. In this paper, the design and fabrication of a flexible naked-eye 3D display film element based on a microstructure have been...

  • Article
  • Open Access
31 Citations
6,037 Views
18 Pages

8 December 2019

A piezoelectric actuator using a lever mechanism is designed, fabricated, and tested with the aim of accomplishing long-travel precision linear driving based on the stick-slip principle. The proposed actuator mainly consists of a stator, an adjustmen...

  • Article
  • Open Access
24 Citations
8,635 Views
13 Pages

7 December 2019

Micro-scale light emitting diodes (micro-LEDs) commonly employ a thin-film flip-chip (TFFC) structure whose substrate is lifted off by an excimer laser. However, flip-chip (FC) micro-LEDs with a substrate can provide a sharp rise on sidewall emission...

  • Article
  • Open Access
22 Citations
4,381 Views
14 Pages

A Compound Control Based on the Piezo-Actuated Stage with Bouc–Wen Model

  • Jiwen Fang,
  • Jia Wang,
  • Chong Li,
  • Wei Zhong and
  • Zhili Long

7 December 2019

The piezoelectric actuator (PA) is one of the most commonly used actuators in a micro-positioning stage. But its hysteresis non-linearity can cause error in the piezo-actuated stage. A modified Bouc–Wen model is presented in this paper to descr...

  • Article
  • Open Access
31 Citations
4,111 Views
12 Pages

Aperture Ratio Improvement by Optimizing the Voltage Slope and Reverse Pulse in the Driving Waveform for Electrowetting Displays

  • Zichuan Yi,
  • Wenyong Feng,
  • Li Wang,
  • Liming Liu,
  • Yue Lin,
  • Wenyao He,
  • Lingling Shui,
  • Chongfu Zhang,
  • Zhi Zhang and
  • Guofu Zhou

7 December 2019

Electrowetting display (EWD) performance is severely affected by ink distribution and charge trapping in pixel cells. Therefore, a multi structural driving waveform is proposed for improving the aperture ratio of EWDs. In this paper, the hysteresis c...

  • Review
  • Open Access
53 Citations
9,597 Views
20 Pages

Phage-based Electrochemical Sensors: A Review

  • Jingting Xu,
  • Ying Chau and
  • Yi-kuen Lee

6 December 2019

Phages based electrochemical sensors have received much attention due to their high specificity, sensitivity and simplicity. Phages or bacteriophages provide natural affinity to their host bacteria cells and can serve as the recognition element for e...

  • Article
  • Open Access
20 Citations
4,497 Views
10 Pages

6 December 2019

Ischemia, lack of blood supply, is associated with a variety of life-threatening cardiovascular diseases, including acute ischemic stroke and myocardial infraction. While blood flow restoration is critical to prevent further damage, paradoxically, ra...

  • Article
  • Open Access
22 Citations
4,738 Views
12 Pages

Vertical Field Emission Air-Channel Diodes and Transistors

  • Wen-Teng Chang,
  • Hsu-Jung Hsu and
  • Po-Heng Pao

6 December 2019

Vacuum channel transistors are potential candidates for low-loss and high-speed electronic devices beyond complementary metal-oxide-semiconductors (CMOS). When the nanoscale transport distance is smaller than the mean free path (MFP) in atmospheric p...

  • Article
  • Open Access
3 Citations
3,139 Views
11 Pages

6 December 2019

Reports on measurements of the rotational velocity by using giant magnetoimpedance (GMI) sensors are rarely seen. In this study, a rotational-velocity sensing system based on GMI effect was established to measure rotational velocities of brushless di...

  • Article
  • Open Access
9 Citations
5,938 Views
10 Pages

A Novel GaN Metal-Insulator-Semiconductor High Electron Mobility Transistor Featuring Vertical Gate Structure

  • Zhonghao Sun,
  • Huolin Huang,
  • Nan Sun,
  • Pengcheng Tao,
  • Cezhou Zhao and
  • Yung C. Liang

5 December 2019

A novel structure scheme by transposing the gate channel orientation from a long horizontal one to a short vertical one is proposed and verified by technology computer-aided design (TCAD) simulations to achieve GaN-based normally-off high electron mo...

  • Article
  • Open Access
10 Citations
4,759 Views
12 Pages

5 December 2019

The modular-based multi-organ-on-a-chip enables more stable and flexible configuration to better mimic the complex biological phenomena for versatile biomedical applications. However, the existing magnetic-based interconnection modes are mainly reali...

  • Article
  • Open Access
12 Citations
5,296 Views
14 Pages

Effect of Enhanced Squeezing Needle Structure on the Jetting Performance of a Piezostack-Driven Dispenser

  • Xiang Huang,
  • Xiaolong Lin,
  • Hang Jin,
  • Siying Lin,
  • Zhenxiang Bu,
  • Gonghan He,
  • Daoheng Sun and
  • Lingyun Wang

5 December 2019

Advanced dispensing technology is urgently needed to improve the jetting performance of fluid to meet the requirements of electronic product integration and miniaturization. In this work, an on–off valve piezostack-driven dispenser was used as...

  • Feature Paper
  • Brief Report
  • Open Access
9 Citations
3,929 Views
11 Pages

A New Microfluidic Platform for Studying Natural Killer Cell and Dendritic Cell Interactions

  • Jolly Hipolito,
  • Hagit Peretz-Soroka,
  • Manli Zhang,
  • Ke Yang,
  • Soheila Karimi-Abdolrezaee,
  • Francis Lin and
  • Sam K.P. Kung

5 December 2019

The importance of the bi-directional natural killer–dendritic cell crosstalk in coordinating anti-tumour and anti-microbial responses in vivo has been well established. However, physical parameters associated with natural killer–dendritic cell intera...

  • Communication
  • Open Access
24 Citations
15,995 Views
15 Pages

Development of a Lab-on-a-Disk Platform with Digital Imaging for Identification and Counting of Parasite Eggs in Human and Animal Stool

  • Sertan Sukas,
  • Bieke Van Dorst,
  • Agata Kryj,
  • Ole Lagatie,
  • Wim De Malsche and
  • Lieven J. Stuyver

5 December 2019

We present a lab-on-a-disk technology for fast identification and quantification of parasite eggs in stool. We introduce a separation and packing method of eggs contained in 1 g of stool, allowing for removal of commonly present solid particles, fat...

  • Article
  • Open Access
19 Citations
6,344 Views
11 Pages

Influence of Pulsed He–Ne Laser Irradiation on the Red Blood Cell Interaction Studied by Optical Tweezers

  • Ruixue Zhu,
  • Tatiana Avsievich,
  • Alexander Bykov,
  • Alexey Popov and
  • Igor Meglinski

5 December 2019

Optical Tweezers (OT), as a revolutionary innovation in laser physics, has been extremely useful in studying cell interaction dynamics at a single-cell level. The reversible aggregation process of red blood cells (RBCs) has an important influence on...

  • Article
  • Open Access
10 Citations
4,264 Views
12 Pages

5 December 2019

Microfluidic mixers have been extensively studied due to their wide application in various fields, including clinical diagnosis and chemical research. In this paper, we demonstrate a mixing platform that can be used for low- and high-viscosity liquid...

  • Article
  • Open Access
8 Citations
3,126 Views
16 Pages

4 December 2019

More efficient heat sinks are required due to the rapid increase of power density in microelectronic devices. In this study, a micro-array heat sink with stagger trapezoidal bumps was designed. Numerical simulations for the flow and heat transfer und...

  • Article
  • Open Access
5 Citations
3,568 Views
12 Pages

4 December 2019

Microstructures on metal surfaces with diameters of tens to hundreds of micrometers and depths of several micrometers to tens of micrometers can improve the performance of engineering parts. Air-shielding electrochemical micromachining (AS-EMM) is a...

  • Feature Paper
  • Article
  • Open Access
12 Citations
4,218 Views
11 Pages

Alpha Particle Effect on Multi-Nanosheet Tunneling Field-Effect Transistor at 3-nm Technology Node

  • Jungmin Hong,
  • Jaewoong Park,
  • Jeawon Lee,
  • Jeonghun Ham,
  • Kiron Park and
  • Jongwook Jeon

4 December 2019

The radiation effects on a multi-nanosheet tunneling-based field effect transistor (NS-TFET) were investigated for a 3-nm technology node using a three-dimensional (3D) technology computer-aided design (TCAD) simulator. An alpha particle was injected...

  • Article
  • Open Access
41 Citations
4,426 Views
15 Pages

3 December 2019

The present work proposes a planar micromixer design comprising hybrid mixing modules of split-and-recombine units and curved channels with radial baffles. The mixing performance was evaluated numerically by solving the continuity and momentum equati...

  • Review
  • Open Access
36 Citations
4,927 Views
20 Pages

2 December 2019

Micromanipulation is an interdisciplinary technology that integrates advanced knowledge of microscale/nanoscale science, mechanical engineering, electronic engineering, and control engineering. Over the past two decades, it has been widely applied in...

  • Feature Paper
  • Article
  • Open Access
15 Citations
4,987 Views
13 Pages

On-Chip Construction of Multilayered Hydrogel Microtubes for Engineered Vascular-Like Microstructures

  • Tao Yue,
  • Na Liu,
  • Yuanyuan Liu,
  • Yan Peng,
  • Shaorong Xie,
  • Jun Luo,
  • Qiang Huang,
  • Masaru Takeuchi and
  • Toshio Fukuda

1 December 2019

Multilayered and multicellular structures are indispensable for constructing functional artificial tissues. Engineered vascular-like microstructures with multiple layers are promising structures to be functionalized as artificial blood vessels. In th...

  • Article
  • Open Access
5 Citations
3,684 Views
15 Pages

A Potential Application of Triangular Microwells to Entrap Single Cancer Cells: A Canine Cutaneous Mast Cell Tumor Model

  • Dettachai Ketpun,
  • Alongkorn Pimpin,
  • Tewan Tongmanee,
  • Sudchaya Bhanpattanakul,
  • Prapruddee Piyaviriyakul,
  • Weerayut Srituravanich,
  • Witsaroot Sripumkhai,
  • Wutthinan Jeamsaksiri and
  • Achariya Sailasuta

1 December 2019

Cellular heterogeneity is a major hindrance, leading to the misunderstanding of dynamic cell biology. However, single cell analysis (SCA) has been used as a practical means to overcome this drawback. Many contemporary methodologies are available for...

  • Article
  • Open Access
7 Citations
3,485 Views
16 Pages

1 December 2019

In order to solve the problem of continuous and stable power supply for vehicle sensors, a resonant cavity piezoelectric energy harvester driven by driving wind pressure was designed. The harvester has an effective working range of wind speed. Accord...

  • Feature Paper
  • Article
  • Open Access
21 Citations
5,928 Views
13 Pages

Automated Pre-Analytic Processing of Whole Saliva Using Magnet-Beating for Point-of-Care Protein Biomarker Analysis

  • Benita Johannsen,
  • Lara Müller,
  • Desirée Baumgartner,
  • Lena Karkossa,
  • Susanna M. Früh,
  • Nagihan Bostanci,
  • Michal Karpíšek,
  • Roland Zengerle,
  • Nils Paust and
  • Konstantinos Mitsakakis

30 November 2019

Saliva offers many advantages for point-of-care (PoC) diagnostic applications due to non-invasive, easy, and cost-effective methods of collection. However, the complex matrix with its non-Newtonian behavior and high viscosity poses handling challenge...

  • Review
  • Open Access
5 Citations
6,004 Views
19 Pages

30 November 2019

Focused soft X-ray beam induced deposition (FXBID) is a novel technique for direct-write nanofabrication of metallic nanostructures from metal organic precursor gases. It combines the established concepts of focused electron beam induced processing (...

of 2

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Micromachines - ISSN 2072-666X