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Review

Epithelioid Cutaneous Mesenchymal Neoplasms: A Practical Diagnostic Approach

1
Department of Pathology, Yeungnam University College of Medicine, Daegu 42415, Korea
2
Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Weill Medical College of Cornell University, Houston, TX 77030, USA
*
Author to whom correspondence should be addressed.
Diagnostics 2020, 10(4), 233; https://doi.org/10.3390/diagnostics10040233
Submission received: 27 March 2020 / Revised: 15 April 2020 / Accepted: 16 April 2020 / Published: 17 April 2020
(This article belongs to the Special Issue Melanoma and Skin Cancer)

Abstract

Epithelioid cells are rounded or polygonal cells with abundant eosinophilic or clear cytoplasm and ovoid to round nuclei, superficially resembling epithelial cells. Cutaneous mesenchymal neoplasms composed predominantly or exclusively of epithelioid cells are relatively uncommon and can cause considerable diagnostic difficulties due to overlapping histologic features among heterogeneous groups of tumors. Familiarity with practical diagnostic approaches and recognition of key histopathologic features are important for correct diagnosis and management. This review summarizes the histologic features of epithelioid cutaneous mesenchymal neoplasms and discusses their differential diagnoses from malignant melanomas and carcinomas.
Keywords: skin neoplasms; diagnosis; epithelioid cells; sarcoma; melanoma; carcinoma skin neoplasms; diagnosis; epithelioid cells; sarcoma; melanoma; carcinoma

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MDPI and ACS Style

Choi, J.H.; Ro, J.Y. Epithelioid Cutaneous Mesenchymal Neoplasms: A Practical Diagnostic Approach. Diagnostics 2020, 10, 233. https://doi.org/10.3390/diagnostics10040233

AMA Style

Choi JH, Ro JY. Epithelioid Cutaneous Mesenchymal Neoplasms: A Practical Diagnostic Approach. Diagnostics. 2020; 10(4):233. https://doi.org/10.3390/diagnostics10040233

Chicago/Turabian Style

Choi, Joon Hyuk, and Jae Y. Ro. 2020. "Epithelioid Cutaneous Mesenchymal Neoplasms: A Practical Diagnostic Approach" Diagnostics 10, no. 4: 233. https://doi.org/10.3390/diagnostics10040233

APA Style

Choi, J. H., & Ro, J. Y. (2020). Epithelioid Cutaneous Mesenchymal Neoplasms: A Practical Diagnostic Approach. Diagnostics, 10(4), 233. https://doi.org/10.3390/diagnostics10040233

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