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Antioxidants, Volume 8, Issue 2

2019 February - 23 articles

Cover Story: The antioxidant activity of ascorbic acid (vitamin C) is counteracted by its reactivity with oxygen, which turns into superoxide, becoming prooxidant. Vitamin C is also unproductively depleted, particularly in water at physiologic pH, where it is dissociated to the less-stable ascorbate. Loading ascorbic acid into the alkaline inner lumen of natural halloysite nanotubes protects it from oxygen and allows slower release in time to quench peroxyl radicals. Through this method, antioxidant activity is boosted 4-fold! View Paper here.
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Articles (23)

  • Article
  • Open Access
136 Citations
13,613 Views
12 Pages

Antioxidant and Anti-Inflammatory Properties of Nigella sativa Oil in Human Pre-Adipocytes

  • Laura Bordoni,
  • Donatella Fedeli,
  • Cinzia Nasuti,
  • Filippo Maggi,
  • Fabrizio Papa,
  • Martin Wabitsch,
  • Raffaele De Caterina and
  • Rosita Gabbianelli

25 February 2019

The oil obtained from the seeds of Nigella sativa L. (N. sativa), also known as black cumin, is frequently used in the Mediterranean area for its anti-inflammatory, anti-oxidant, and anti-cancer activities. The aim of the present study was to evaluat...

  • Article
  • Open Access
15 Citations
6,238 Views
17 Pages

24 February 2019

When healthy adults consume carbohydrates at night, postprandial blood glucose responses are elevated and prolonged compared to daytime.Extended postprandial hyperglycaemia is a risk factor for type 2 diabetes. Polyphenols are bioactive secondary met...

  • Review
  • Open Access
90 Citations
12,039 Views
23 Pages

Hydrogen Sulfide and Persulfides Oxidation by Biologically Relevant Oxidizing Species

  • Dayana Benchoam,
  • Ernesto Cuevasanta,
  • Matías N. Möller and
  • Beatriz Alvarez

22 February 2019

Hydrogen sulfide (H2S/HS) can be formed in mammalian tissues and exert physiological effects. It can react with metal centers and oxidized thiol products such as disulfides (RSSR) and sulfenic acids (RSOH). Reactions with oxidized thiol produc...

  • Article
  • Open Access
25 Citations
6,837 Views
12 Pages

Comparison of the Phenolic Profiles of Soaked and Germinated Peanut Cultivars via UPLC-QTOF-MS

  • Qiong-Qiong Yang,
  • Lin Cheng,
  • Zhi-Yuan Long,
  • Hua-Bin Li,
  • Anil Gunaratne,
  • Ren-You Gan and
  • Harold Corke

20 February 2019

Diverse peanut varieties are widely cultivated in China. However, few studies have investigated the effects of germination on the phenolic profiles and antioxidant activities of specific Chinese peanut cultivars. Therefore, this study was conducted t...

  • Review
  • Open Access
58 Citations
11,284 Views
10 Pages

Antioxidant Defense Mechanisms in Erythrocytes and in the Central Nervous System

  • Rafael Franco,
  • Gemma Navarro and
  • Eva Martínez-Pinilla

18 February 2019

Differential antioxidant action is found upon comparison of organ/tissue systems in the human body. In erythrocytes (red blood cells), which transport oxygen and carbon dioxide through the circulatory system, the most important issue is to keep hemog...

  • Review
  • Open Access
57 Citations
52,333 Views
10 Pages

16 February 2019

Longevity is determined by a number of factors, including genetic, environmental and lifestyle factors. A major factor affecting longevity is the development of degenerative disorders such as cardiovascular disease, diabetes, kidney disease and liver...

  • Review
  • Open Access
71 Citations
10,103 Views
10 Pages

16 February 2019

The winemaking industry produces large amount of byproducts, including grape pomace, stalks, and lees. Wine lees are a natural source of phenolic compounds, which have important antioxidant and biological properties. Due to the high quantities produc...

  • Article
  • Open Access
67 Citations
8,478 Views
19 Pages

Bioactive Phenolic Compounds from the Agroindustrial Waste of Colombian Mango Cultivars ‘Sugar Mango’ and ‘Tommy Atkins’—An Alternative for Their Use and Valorization

  • Henry I. Castro-Vargas,
  • Diego Ballesteros Vivas,
  • Jenny Ortega Barbosa,
  • Sandra Johanna Morantes Medina,
  • Fabio Aristizabal Gutiérrez and
  • Fabián Parada-Alfonso

15 February 2019

The aim of this study was to explore the potential of the agroindustrial waste from two Colombian mango cultivars as sources of bioactive phenolic compounds. Phenolic extracts from mango waste (peels, seed coats, and seed kernels) of ‘sugar man...

  • Article
  • Open Access
11 Citations
9,882 Views
15 Pages

Hystrix Brachyura Bezoar Characterization, Antioxidant Activity Screening, and Anticancer Activity on Melanoma Cells (A375): A Preliminary Study

  • Al’aina Yuhainis Firus Khan,
  • Faizah Abdullah Asuhaimi,
  • Tara K. Jalal,
  • Fatimah Opeyemi Roheem,
  • Hatim Abdullah Natto,
  • Muhammad Farid Johan,
  • Qamar Uddin Ahmed and
  • Ridhwan Abdul Wahab

12 February 2019

Porcupine bezoars (PBs) are masses of undigested calcareous concretions formed within the gastrointestinal tract. There are undocumented claims that PBs have antioxidant activity and can treat cancers. However, limited scientific study has been carri...

  • Article
  • Open Access
17 Citations
4,737 Views
10 Pages

9 February 2019

Thirty-six pregnant Holstein–Friesian cows were used to study the effect of Yerba Mate (YM) supplementation during the dry period on redox balance. The treatments groups were Control (no YM), YM 250 (250 g/cow/day), and YM 500 (500 g/cow/day)....

  • Article
  • Open Access
52 Citations
8,701 Views
16 Pages

Evaluation of the In Vitro Wound-Healing Activity of Calabrian Honeys

  • Paolo Governa,
  • Gabriele Carullo,
  • Marco Biagi,
  • Vittoria Rago and
  • Francesca Aiello

6 February 2019

The healing of skin wounds and particularly chronic wounds, such as diabetic foot ulcers, is still a clinical emergency. Despite the many therapeutic tools that are available so far, none seems to be really effective and safe. In this context, we hig...

  • Article
  • Open Access
40 Citations
7,579 Views
11 Pages

Optimization of the Microwave-Assisted Extraction Process of Bioactive Compounds from Annatto Seeds (Bixa orellana L.)

  • Julian Quintero Quiroz,
  • Angélica Celis Torres,
  • Luisa Muñoz Ramirez,
  • Mariluz Silva Garcia,
  • Gelmy Ciro Gomez and
  • John Rojas Camargo

6 February 2019

This study deals with the extraction, optimization, and evaluation of the antioxidant and antimicrobial activities of bioactive compounds obtained from the seeds of annatto using microwave-assisted extraction as compared to leaching. Annatto seeds we...

  • Review
  • Open Access
504 Citations
31,517 Views
28 Pages

5 February 2019

Inflammation has been reported to be intimately linked to the development or worsening of several non-infectious diseases. A number of chronic conditions such as cancer, diabetes, cardiovascular disorders, autoimmune diseases, and neurodegenerative d...

  • Article
  • Open Access
23 Citations
5,829 Views
11 Pages

Correction of Experimental Retinal Ischemia by l-Isomer of Ethylmethylhydroxypyridine Malate

  • Anna Peresypkina,
  • Anton Pazhinsky,
  • Mikhail Pokrovskii,
  • Evgenya Beskhmelnitsyna,
  • Anna Pobeda and
  • Mikhail Korokin

3 February 2019

An important task of pharmacology and ophtalmology is to find specific and highly effective agents for correcting retinal ischemia. The objective of this study is to increase the effectiveness of pharmacological correction of retinal ischemia by usin...

  • Perspective
  • Open Access
33 Citations
8,236 Views
9 Pages

2 February 2019

Mitochondrial dihydrolipoamide dehydrogenase (DLDH) is a redox enzyme involved in decarboxylation of pyruvate to form acetyl-CoA during the cascade of glucose metabolism and mitochondrial adenine triphosphate (ATP) production. Depending on physiologi...

  • Article
  • Open Access
20 Citations
6,218 Views
14 Pages

Hyperoxidation of Peroxiredoxin 6 Induces Alteration from Dimeric to Oligomeric State

  • Sharifun Shahnaj,
  • Rimpy Kaur Chowhan,
  • Potshangbam Angamba Meetei,
  • Pushpa Kakchingtabam,
  • Khundrakpam Herojit Singh,
  • Laishram Rajendrakumar Singh,
  • Potshangbam Nongdam,
  • Aron B. Fisher and
  • Hamidur Rahaman

2 February 2019

Peroxiredoxins(Prdx), the family of non-selenium glutathione peroxidases, are important antioxidant enzymes that defend our system from the toxic reactive oxygen species (ROS). They are thiol-based peroxidases that utilize self-oxidation of their per...

  • Article
  • Open Access
6 Citations
3,791 Views
9 Pages

31 January 2019

Antioxidants in the liver are particularly abundant in capital breeders that rely on stored resources for egg production. Capital breeders like eider (hereafter common eider) Somateria mollissima have disproportionately large livers with low levels o...

  • Article
  • Open Access
33 Citations
6,769 Views
17 Pages

Enhanced Antioxidant Activity under Biomimetic Settings of Ascorbic Acid Included in Halloysite Nanotubes

  • Andrea Baschieri,
  • Riccardo Amorati,
  • Tiziana Benelli,
  • Laura Mazzocchetti,
  • Emanuele D’Angelo and
  • Luca Valgimigli

27 January 2019

Antioxidant activity of native vitamin C (ascorbic acid, AH2) is hampered by instability in solution. Selective loading of AH2 into the inner lumen of natural halloysite nanotubes (HNT) yields a composite nanoantioxidant (HNT/AH2), which was characte...

  • Review
  • Open Access
25 Citations
7,649 Views
22 Pages

23 January 2019

Reactive oxygen and nitrogen species have cell signaling properties and are involved in a multitude of processes beyond redox homeostasis. The peroxiredoxin (Prdx) proteins are highly sensitive intracellular peroxidases that can coordinate cell signa...

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Antioxidants - ISSN 2076-3921