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Biology, Volume 2, Issue 3

2013 September - 13 articles

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Articles (13)

  • Article
  • Open Access
4 Citations
8,533 Views
24 Pages

13 September 2013

Deep water samples (ca. 4,200 m) were taken from two hydrologically-similar sites around the Crozet islands with highly contrasting surface water productivities. Site M5 was characteristic of high productivity waters (high chlorophyll) whilst site M6...

  • Article
  • Open Access
65 Citations
12,757 Views
15 Pages

12 September 2013

The development of multicellular eukaryotes, according to their body plan, is often directed by members of multigene families that encode transcription factors. MADS (for MINICHROMOSOME MAINTENANCE1, AGAMOUS, DEFICIENS and SERUM RESPONSE FACTOR)-box...

  • Article
  • Open Access
13 Citations
10,177 Views
15 Pages

3 September 2013

Adhesion of bacteria to the glycosylated surface of their target cells is typically mediated by fimbrial lectins, exposed on the bacterial surface. Among the best-investigated and most important fimbriae are type 1 fimbriae, for which α-d-mannopyrano...

  • Review
  • Open Access
159 Citations
22,640 Views
25 Pages

27 August 2013

Helicobacter pylori is one of the most successful human pathogens, which colonizes the mucus layer of the gastric epithelium of more than 50% of the world’s population. This curved, microaerophilic, Gram-negative bacterium induces a chronic active ga...

  • Review
  • Open Access
39 Citations
23,551 Views
56 Pages

The Biology of Neisseria Adhesins

  • Miao-Chiu Hung and
  • Myron Christodoulides

29 July 2013

Members of the genus Neisseria include pathogens causing important human diseases such as meningitis, septicaemia, gonorrhoea and pelvic inflammatory disease syndrome. Neisseriae are found on the exposed epithelia of the upper respiratory tract and t...

  • Article
  • Open Access
18 Citations
9,729 Views
20 Pages

26 July 2013

Measurement of gases entrapped in clean ice from basal portions of the Taylor Glacier, Antarctica, revealed that CO2 ranged from 229 to 328 ppmv and O2 was near 20% of the gas volume. In contrast, vertically adjacent sections of the sediment laden ba...

  • Review
  • Open Access
75 Citations
26,185 Views
58 Pages

The Role of Nuclear Bodies in Gene Expression and Disease

  • Marie Morimoto and
  • Cornelius F. Boerkoel

9 July 2013

This review summarizes the current understanding of the role of nuclear bodies in regulating gene expression. The compartmentalization of cellular processes, such as ribosome biogenesis, RNA processing, cellular response to stress, transcription, mod...

  • Review
  • Open Access
45 Citations
15,029 Views
40 Pages

2 July 2013

Oncolytic viruses (OVs) replicate selectively in tumor cells and exert anti-tumor cytotoxic activity. Among them, Newcastle Disease Virus (NDV), a bird RNA virus of the paramyxovirus family, appears outstanding. Its anti-tumor effect is based on: (i)...

  • Article
  • Open Access
20 Citations
9,908 Views
22 Pages

1 July 2013

Global targets to halt the loss of biodiversity have not been met, and there is now an additional Aichi target for preventing the extinction of known threatened species and improving their conservation status. Climate change increasingly needs to be...

  • Article
  • Open Access
25 Citations
11,277 Views
24 Pages

Structural Sampling of Glycan Interaction Profiles Reveals Mucosal Receptors for Fimbrial Adhesins of Enterotoxigenic Escherichia coli

  • Emanuela Lonardi,
  • Kristof Moonens,
  • Lieven Buts,
  • Arjen R. De Boer,
  • Johan D. M. Olsson,
  • Manfred S. Weiss,
  • Emeline Fabre,
  • Yann Guérardel,
  • André M. Deelder and
  • Julie Bouckaert
  • + 2 authors

1 July 2013

Fimbriae are long, proteinaceous adhesion organelles expressed on the bacterial envelope, evolutionarily adapted by Escherichia coli strains for the colonization of epithelial linings. Using glycan arrays of the Consortium for Functional Glycomics (C...

  • Review
  • Open Access
20 Citations
10,328 Views
18 Pages

Bacterial Adhesion of Streptococcus suis to Host Cells and Its Inhibition by Carbohydrate Ligands

  • Annika Kouki,
  • Roland J. Pieters,
  • Ulf J. Nilsson,
  • Vuokko Loimaranta,
  • Jukka Finne and
  • Sauli Haataja

1 July 2013

Streptococcus suis is a Gram-positive bacterium, which causes sepsis and meningitis in pigs and humans. This review examines the role of known S. suis virulence factors in adhesion and S. suis carbohydrate-based adhesion mechanisms, as well as the in...

  • Article
  • Open Access
4 Citations
9,141 Views
11 Pages

A Versatile Tool for Stable Inhibition of microRNA Activity

  • Paride Pelucchi,
  • Valeria Tria,
  • Valentina Martino,
  • Davood Sabour,
  • Giovanni Bertalot,
  • Stefano Molgora,
  • Mira Palizban,
  • Martin Götte,
  • Ileana Zucchi and
  • Rolland A. Reinbold

28 June 2013

MicroRNAs (miRNAs) are a class of small RNAs (18–22 nt) that post transcriptionally regulate gene expression by binding to complementary sequences on target mRNAs, resulting in translational repression or target degradation and gene silencing. As abe...

  • Review
  • Open Access
10 Citations
10,312 Views
20 Pages

26 June 2013

Type I and P pili are chaperone-usher pili of uropathogenic Escherichia coli, which allow bacteria to adhere to host cell receptors. Pilus formation and secretion are orchestrated by two accessory proteins, a chaperone, which catalyses pilus subunit...

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Biology - ISSN 2079-7737