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Children, Volume 10, Issue 5

2023 May - 149 articles

Cover Story: Ultra-rapid genomic sequencing is increasingly being used in neonatal and pediatric intensive care settings, demonstrating high diagnostic and clinical utility. Arkell and colleagues conducted focus groups with 19 healthcare professionals (including clinical geneticists, genetic counselors, and intensivists) to explore their experiences with ultra-rapid genomic sequencing, particularly when making treatment decisions. They identified that healthcare professionals find it challenging to set realistic expectations with families regarding the outcomes of ultra-rapid genomic sequencing. These healthcare professionals reported modifying pre-test counseling to include life-limiting diagnoses as a possible test outcome. Healthcare professionals explained that moral distress arose when families and healthcare professionals’ treatment goals were misaligned after a diagnosis was received. View this paper
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Articles (149)

  • Article
  • Open Access
3 Citations
3,520 Views
11 Pages

Association between being Overweight in Young Childhood and during School Age and Puberty

  • Genki Shinoda,
  • Yudai Nagaoka,
  • Fumihiko Ueno,
  • Naoyuki Kurokawa,
  • Ippei Takahashi,
  • Tomomi Onuma,
  • Aoi Noda,
  • Keiko Murakami,
  • Mami Ishikuro and
  • Shinichi Kuriyama
  • + 3 authors

To examine whether body type at birth, body weight, and obesity in early childhood are associated with overweight/obesity during school age and puberty. Data from maternal and child health handbooks, baby health checkup information, and school physic...

  • Review
  • Open Access
8 Citations
7,514 Views
18 Pages

Functioning, as described in the International Classification of Functioning, Disability and Health (ICF), increasingly raises interest in the world of child rehabilitation, especially because its application empowers patients and parents by not putt...

  • Review
  • Open Access
63 Citations
16,750 Views
17 Pages

Maternal Infection and Preterm Birth: From Molecular Basis to Clinical Implications

  • George Daskalakis,
  • Alexandros Psarris,
  • Antonios Koutras,
  • Zacharias Fasoulakis,
  • Ioannis Prokopakis,
  • Antonia Varthaliti,
  • Christina Karasmani,
  • Thomas Ntounis,
  • Ekaterini Domali and
  • Angeliki Papapanagiotou
  • + 3 authors

As the leading cause of neonatal morbidity and mortality, preterm birth is recognized as a major public health concern around the world. The purpose of this review is to analyze the connection between infections and premature birth. Spontaneous prete...

  • Review
  • Open Access
2 Citations
3,695 Views
14 Pages

The Healthcare Experience of Autistic Patients in Orthopaedic Surgery and Closely Related Fields: A Scoping Review

  • Steven D. Criss,
  • Shravya Kakulamarri,
  • Raylin F. Xu,
  • Maya Fajardo,
  • Tamra Keeney,
  • Dorothy W. Tolchin and
  • Collin J. May

Orthopaedic and related care has the potential to present unique obstacles for patients with a range of autism manifestations. In this review, we aim to describe and analyze the literature on autistic patients’ experience within orthopaedics an...

  • Article
  • Open Access
6 Citations
3,134 Views
11 Pages

Somatic complaints during preadolescence are connected to individual and contextual factors, and extant research highlights the relevance of alexithymia and bullying involvement. In this cross-sectional study, we explored the joint and unique influen...

  • Article
  • Open Access
3,308 Views
15 Pages

Background: The current social construction of young mothers is generally negative, pointing to a lack of engagement with universal services and poor outcomes for their infants and children. However, qualitative studies offer an alternative, more pos...

  • Article
  • Open Access
7 Citations
2,396 Views
10 Pages

Molar incisor hypomineralization (MIH) and deciduous molar hypomineralization (DMH) affect the first permanent molars and second primary molars, respectively, causing a greater dental treatment burden and worse oral health quality of life among affec...

  • Article
  • Open Access
4 Citations
3,960 Views
17 Pages

Whole Exome-Trio Analysis Reveals Rare Variants Associated with Congenital Pouch Colon

  • Sonal Gupta,
  • Praveen Mathur,
  • Ashwani Kumar Mishra,
  • Krishna Mohan Medicherla,
  • Obul Reddy Bandapalli and
  • Prashanth Suravajhala

Anorectal malformations (ARM) are individually common, but Congenital Pouch Colon (CPC) is a rare anorectal anomaly that causes a dilated pouch and communication with the genitourinary tract. In this work, we attempted to identify de novo heterozygou...

  • Case Report
  • Open Access
3 Citations
2,729 Views
9 Pages

Introduction: Charcot–Marie–Tooth (CMT) is a group of inherited peripheral neuropathies characterized by wide genotypic and phenotypic variability. The onset is typically in childhood, and the most frequent clinical manifestations are pre...

  • Case Report
  • Open Access
2 Citations
2,414 Views
7 Pages

Pediatric Pancreatic Endocrine Tumor Presenting as Acute Pancreatitis: A Case Report

  • Shigetaka Fukuda,
  • Mitsuyoshi Suzuki,
  • Kei Minowa,
  • Hiroyuki Koga,
  • Atsuyuki Yamataka and
  • Toshiaki Shimizu

Pancreatic neuroendocrine tumors (PNETs) are relatively rare, especially in the pediatric age group. This report describes a pediatric case of acute pancreatitis secondary to stenosis of the main pancreatic duct due to a PNET. The patient was a boy,...

  • Article
  • Open Access
5 Citations
3,655 Views
13 Pages

Comparison between Nasopharyngeal and Saliva Samples for the Detection of Respiratory Viruses in Children with Acute Lower Respiratory Tract Infections: A Pilot Study

  • Danilo Buonsenso,
  • Piero Valentini,
  • Francesco Mariani,
  • Silvia Di Noi,
  • Sofia Mazza,
  • Ivana Palucci,
  • Maurizio Sanguinetti and
  • Michela Sali

Purpose: During the COVID-19 pandemic, the use of salivary swabs (SS) to detect the SARS-CoV-2 virus has been implemented and widely studied in adults and children. However, the role of SS in detecting other common respiratory viruses in children is...

  • Article
  • Open Access
8 Citations
3,120 Views
10 Pages

Comparative Evaluation of Extrusion of Apical Debris in Primary Maxillary Anterior Teeth Using Two Different Rotary Systems and Hand Files: An In Vitro Study

  • Balaji Suresh,
  • Ganesh Jeevanandan,
  • Vignesh Ravindran,
  • Mohammed Mashyakhy,
  • Noura Alessa,
  • Ather Ahmed Syed,
  • Suman Panda,
  • Ali Ahmed Assiry,
  • Prabhadevi C. Maganur and
  • Satish Vishwanathaiah

Successful outcome of pulp therapy depends on good chemomechanical preparation of the canals. This is completed with the help of various upcoming rotary and hand files. However, during this preparation, there might be an apical extrusion of the debri...

  • Review
  • Open Access
3 Citations
3,302 Views
21 Pages

Translating Precision Health for Pediatrics: A Scoping Review

  • Mathushan Subasri,
  • Celine Cressman,
  • Danielle Arje,
  • Leighton Schreyer,
  • Erin Cooper,
  • Komal Patel,
  • Wendy J. Ungar,
  • Melanie Barwick,
  • Avram Denburg and
  • Robin Z. Hayeems

Precision health aims to personalize treatment and prevention strategies based on individual genetic differences. While it has significantly improved healthcare for specific patient groups, broader translation faces challenges with evidence developme...

  • Article
  • Open Access
3 Citations
4,515 Views
14 Pages

Understanding the Family Context: A Qualitative Descriptive Study of Parent and NICU Clinician Experiences and Perspectives

  • Maya Dahan,
  • Leahora Rotteau,
  • Shelley Higazi,
  • Ophelia Kwayke,
  • Giselle Lai,
  • Wendy Moulsdale,
  • Lisa Sampson,
  • Jennifer Stannard,
  • Paige Terrien Church and
  • Karel O’Brien

Enabling individualized decision-making for patients requires an understanding of the family context (FC) by healthcare providers. The FC is everything that makes the family unique, from their names, preferred pronouns, family structure, cultural or...

  • Article
  • Open Access
11 Citations
3,498 Views
20 Pages

Evolution of Youth’s Mental Health and Quality of Life during the COVID-19 Pandemic in South Tyrol, Italy: Comparison of Two Representative Surveys

  • Verena Barbieri,
  • Christian J. Wiedermann,
  • Giuliano Piccoliori,
  • Angelika Mahlknecht,
  • Barbara Plagg,
  • Dietmar Ausserhofer,
  • Ulrike Ravens-Sieberer and
  • Adolf Engl

Background: The coronavirus disease 2019 pandemic has led to an increase in youth mental health problems worldwide. Studies have revealed substantial variation in the incidence of these problems across different regions. Longitudinal studies of child...

  • Case Report
  • Open Access
1,917 Views
7 Pages

Heart Failure Post-SARS-CoV-2 Infection in Children with Duchenne Muscular Dystrophy: The Additive Value of Cardiovascular Magnetic Resonance

  • George Markousis-Mavrogenis,
  • Antonios Belegrinos,
  • Aikaterini Giannakopoulou,
  • Evangelos Karanasios,
  • Vasiliki Vartela,
  • Elephtheria Patsilinakou,
  • Paul Samantis,
  • Roser-Marie Pons,
  • Antigoni Papavasiliou and
  • Sophie I. Mavrogeni

In this case series, we describe the diagnosis of post-COVID-19 myocarditis in asymptomatic patients with Duchenne Muscular Dystrophy (DMD) and a mild COVID-19 disease course. These patients were referred for CMR due to electrocardiographic and echoc...

  • Article
  • Open Access
5 Citations
2,492 Views
12 Pages

Factors Associated with Atopic Dermatitis among Children Aged 6 to 14 Years in Alimosho Local Government, Lagos, Nigeria

  • Olubunmi A. Kayode,
  • Charlotte M. Mokoatle,
  • Phoka C. Rathebe and
  • Thokozani P. Mbonane

There has been a rise in the prevalence of atopic dermatitis (AD) globally, especially in low-and middle-income countries such as Nigeria. The condition has been linked to genetic predisposes, living conditions, and environmental factors. Environment...

  • Article
  • Open Access
9 Citations
4,215 Views
13 Pages

Clinical and Functional Characteristics of a New Phenotype of SMA Type I among a National Sample of Spanish Children: A Cross-Sectional Study

  • Beatriz de-Andrés-Beltrán,
  • Javier Güeita-Rodríguez,
  • Domingo Palacios-Ceña and
  • Ángel Luis Rodríguez-Fernández

Spinal Muscular Atrophy (SMA) type I has classically presented extremely severe clinical features. New pharmacological treatments have led to a new phenotype of SMA. The aim of this study was to describe the current health and functional status of ch...

  • Article
  • Open Access
3 Citations
5,116 Views
13 Pages

Prevalence and Predictors of Alcohol Use among School-Going Adolescents in Panama: A Population-Based Cross-Sectional Study

  • Paul Obeng,
  • Francis Sambah,
  • Jacob Owusu Sarfo,
  • Medina Srem-Sai,
  • Newton Isaac Gbordzoe,
  • Richmond Stephen Sorkpor and
  • John Elvis Hagan

This study investigated the prevalence and predictors of alcohol use among school-going-age adolescents in Panama. Using a national school-based cross-sectional survey, data from a proportionate sample of school-going adolescents aged 13–17 yea...

  • Article
  • Open Access
4 Citations
2,500 Views
10 Pages

Quality of Life Outcomes for Patients Who Underwent Conventional Resection and Liver Transplantation for Locally Advanced Hepatoblastoma

  • Zishaan Farooqui,
  • Michael Johnston,
  • Emily Schepers,
  • Nathalie Brewer,
  • Stephen Hartman,
  • Todd Jenkins,
  • Alexander Bondoc,
  • Ahna Pai,
  • James Geller and
  • Gregory M. Tiao

Hepatoblastoma is the most common malignant liver tumor of childhood, with liver transplant and extended resection used as surgical treatments for locally advanced tumors. Although each approach has well-described post-operative complications, qualit...

  • Article
  • Open Access
2 Citations
2,383 Views
14 Pages

Home-Based Exercise Training in the Recovery of Multisystem Inflammatory Syndrome in Children: A Case Series Study

  • Camilla Astley,
  • Gabriela Nunes Leal,
  • Saulo Gil,
  • Priscila Suguita,
  • Thais Fink,
  • Vera Bain,
  • Maria Fernanda Badue Pereira,
  • Heloisa Helena Marques,
  • Sofia Sieczkowska and
  • Bruno Gualano
  • + 5 authors

Objective: To assess the potential therapeutic role of exercise on health-related quality of life, assessed by the Pediatric Outcomes Data Collection Instrument (PODCI), coronary flow reserve (CFR), cardiac function, cardiorespiratory fitness, and in...

  • Article
  • Open Access
7 Citations
2,835 Views
12 Pages

Oral Health in migrants children in Melilla, Spain

  • Gunel Kizi,
  • Ana Raquel Barata,
  • Irene Ventura,
  • Javier Flores-Fraile,
  • David Ribas-Perez and
  • Antonio Castaño-Seiquer

Numerous developing countries’ socioeconomic and political issues resulted in a significant migratory phenomenon, which poses a health burden for the nations that receive migrant populations. Often, the greatest age group of migrants is childre...

  • Article
  • Open Access
13 Citations
4,544 Views
12 Pages

Background: Appendectomy is still the standard treatment for acute appendicitis in the majority of centers. Despite all available diagnostic tools, the rates of negative appendectomies are still relatively high. This study aimed to determine negative...

  • Systematic Review
  • Open Access
7 Citations
4,917 Views
15 Pages

Impact of Dental Trauma on Orthodontic Parameters—A Systematic Review and Meta-Analysis

  • Mohammad Khursheed Alam,
  • Mohammed Awawdeh,
  • Ali S. Aljhani,
  • Ghada Serhan Alotaib,
  • Huda Abutayyem,
  • Haytham Jamil Alswairki and
  • Mohammad Younis Hajeer

Background and objectives: Investigation into the impact of dental trauma on the results of orthodontic treatment is crucial because it can have a major influence on patient care. However, there has not yet been a thorough review or meta-analysis of...

  • Editorial
  • Open Access
4 Citations
2,781 Views
3 Pages

The term fluoroscopically guided interventional procedure describes a clinical practice in medicine, where fluoroscopic systems are used to conduct diagnostic procedures or provide image guidance for therapeutic interventional procedures performed vi...

  • Review
  • Open Access
5 Citations
4,622 Views
11 Pages

Juvenile Osteochondral Lesions of the Talus: Current Concepts Review and an Update on the Literature

  • Albert T. Anastasio,
  • Kian Bagheri,
  • Emily M. Peairs,
  • Caitlin Grant and
  • Samuel B. Adams

Osteochondral lesions of the talus (OLTs) are lesions that occur before the physis closes and are frequently associated with acute ankle trauma. These lesions are often difficult to diagnose due to swelling and inflammation that are present after the...

  • Article
  • Open Access
5 Citations
2,743 Views
13 Pages

Genetic Disruption of Cilia-Associated Signaling Pathways in Patients with VACTERL Association

  • Jessica Ritter,
  • Kristina Lisec,
  • Marina Klinner,
  • Martina Heinrich,
  • Dietrich von Schweinitz,
  • Roland Kappler and
  • Jochen Hubertus

VACTERL association is a rare malformation complex consisting of vertebral defects, anorectal malformation, cardiovascular defects, tracheoesophageal fistulae with esophageal atresia, renal malformation, and limb anomalies. According to current knowl...

  • Article
  • Open Access
3,056 Views
20 Pages

Flashbulb Memories in the Communication of the Diagnosis of Visual Impairment: The Effect of Context and Content

  • Mª Emma Mayo Pais,
  • José Eulogio Real Deus,
  • Patricia Mª Iglesias-Souto and
  • Eva Mª Taboada-Ares

The diagnosis of a child’s visual impairment is remembered vividly and intensely by their parents. However, the way in which the diagnosis is communicated may affect the development and persistence of this memory. The aim of this study is to an...

  • Article
  • Open Access
15 Citations
3,549 Views
13 Pages

Redefining Neurodevelopmental Impairment: Perspectives of Very Preterm Birth Stakeholders

  • Anne Synnes,
  • Amarpreet Chera,
  • Lindsay L. Richter,
  • Jeffrey N. Bone,
  • Claude Julie Bourque,
  • Sofia Zhang-Jiang,
  • Rebecca Pearce,
  • Annie Janvier and
  • Thuy Mai Luu

Children born very preterm are at risk of severe neurodevelopmental impairment, a composite endpoint that includes cerebral palsy, developmental delay, and hearing and visual impairment defined by medical professionals. We aimed to describe preterm b...

  • Case Report
  • Open Access
4 Citations
9,900 Views
12 Pages

The article presents a case of bimaxillary dentoalveolar protrusion treated by distalizing the upper and lower teeth, using anchorage from mini implants. A 16-year-old male patient presented with severe upper and lower incisor proclination with protr...

  • Article
  • Open Access
2 Citations
3,557 Views
12 Pages

Emotion Regulation in Toddlerhood: Regulatory Strategies in Anger and Fear Eliciting Contexts at 24 and 30 Months

  • Silvia Ponzetti,
  • Maria Spinelli,
  • Gabrielle Coppola,
  • Francesca Lionetti,
  • Giulio D’Urso,
  • Prachi Shah,
  • Mirco Fasolo and
  • Tiziana Aureli

The study investigated the emergence of toddlers’ regulatory strategies in aversive contexts. Forty-two toddlers were observed at 24 and 30 months of age using two paradigms designed to elicit fear and anger. We examined toddlers’ use of...

  • Article
  • Open Access
9 Citations
3,235 Views
18 Pages

Could the Hybridization of the SE/TGfU Pedagogical Models Be an Alternative for Learning Sports and Promoting Health? School Context Study

  • Ismael López-Lemus,
  • Fernando Del Villar,
  • Amparo Rodríguez-Gutiérrez,
  • Jara González-Silva and
  • Alberto Moreno

The present study aims to analyze the influence of the Sport Education (SE)/Teaching for understanding (TGfU) hybrid unit on enjoyment, perceived competence, intention to be physically active, skill execution, decision making, performance and game in...

  • Article
  • Open Access
7 Citations
2,788 Views
10 Pages

Examination of Upper Extremity Length Discrepancy in Patients with Obstetric Brachial Plexus Paralysis

  • Murat Danisman,
  • Abdulsamet Emet,
  • Ismail Aykut Kocyigit,
  • Ercan Hassa and
  • Akin Uzumcugil

Since the natural course of obstetric brachial plexus palsy is variable, several problems are encountered. One important question, in considering patients with OBPP under observation in outpatient clinical settings, is whether children will have leng...

  • Article
  • Open Access
3 Citations
2,779 Views
11 Pages

Capillary Refill Time and Serum Lactate as Predictors of Mortality and Postoperative Extracorporeal Membrane Oxygenation Requirement in Congenital Heart Surgery

  • Gustavo Cruz,
  • Santiago Pedroza Gómez,
  • Akemi Arango,
  • Paula A. Guevara,
  • Carlos González,
  • Jesus Aguirre,
  • Andrea Valencia-Orozco and
  • Antonio J. Suguimoto

Multiple tissue perfusion markers are described to guide therapy in critically ill pediatric patients undergoing congenital heart surgery. Given the advantages of capillary refill time, our goal is to determine its predictive capacity for mortality a...

  • Case Report
  • Open Access
1,990 Views
8 Pages

Incidental Hyperferritinemia in Very Young Infants with Mild Symptoms of COVID-19 Disease

  • Yuka Shishido,
  • Haruhiko Nakamura,
  • Tomohiro Nakagawa,
  • Shinsuke Kanou,
  • Takeshi Ito,
  • Shota Kuwana and
  • Chiharu Ota

Background: The number of children infected with novel coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has increased during the outbreak of the Omicron strain. Hyperferritinemia has been re...

  • Article
  • Open Access
4 Citations
2,296 Views
11 Pages

The purpose of the present study was to evaluate the factorial structure of the bullying scale on the Trends in International Mathematics and Science (TIMSS 2019) for eighth graders and evaluate the instrument’s invariance across gender so that...

  • Article
  • Open Access
3 Citations
3,944 Views
16 Pages

Despite the many benefits of club-organized sports participation for children, sports participation is lower among children from low-income families than among those from middle- or high-income families. Social safety experienced by parents from low-...

  • Case Report
  • Open Access
1,858 Views
8 Pages

Pirarubicin Combination Low-Dose Chemotherapy for Early Infantile Stage MS Neuroblastoma: Case Report

  • Yutaka Kato,
  • Hiroshi Kawaguchi,
  • Naoki Sakata,
  • Satoshi Ueda,
  • Munehiro Okano,
  • Yuuki Nishino,
  • Masako Ryujin,
  • Yutaka Takemura,
  • Tsukasa Takemura and
  • Satoshi Okada
  • + 1 author

Neuroblastoma (NB) is a neural crest-derived malignant tumor which is diagnosed during infancy in approximately 40% of cases; spontaneous regressions are observed, but there are varying degrees of severity. Treatment is indicated if an infant’s...

  • Article
  • Open Access
6 Citations
2,707 Views
11 Pages

Elevated Urinary Hepcidin Level and Hypoferremia in Infants with Febrile Urinary Tract Infection: A Prospective Cohort Study

  • Yu-Chen Hsu,
  • Hsin-Chun Huang,
  • Kuo-Su Tang,
  • Li-Ting Su,
  • Ying-Hsien Huang,
  • Hui-Chen Huang and
  • I-Lun Chen

To evaluate the kinetics of serum and urinary hepcidin levels along with anemia-related parameters during the infection course of infants with febrile urinary tract infection (UTI), we enrolled febrile infants aged one to four months in this prospect...

  • Article
  • Open Access
5 Citations
2,888 Views
11 Pages

Psychological Well-Being, Self-Esteem, Quality of Life and Gender Differences as Determinants of Post-Traumatic Growth in Long-Term Knee Rotationplasty Survivors: A Cohort Study

  • Maria Grazia Benedetti,
  • Ilaria Tarricone,
  • Manuela Monti,
  • Laura Campanacci,
  • Maria Giulia Regazzi,
  • Tiziano De Matteis,
  • Daniela Platano and
  • Marco Manfrini

Rotationplasty (RP) is a special surgical technique for bone tumors of the lower limb and is the chosen procedure for children under 6 with bone sarcoma in the distal femur. Leg reconstruction results in an unusual aspect of the limb potentially givi...

  • Case Report
  • Open Access
6 Citations
3,862 Views
8 Pages

Pediatric Gaucher Disease Presenting with Massive Splenomegaly and Hepatic Gaucheroma

  • Gianluca Bossù,
  • Laura Pedretti,
  • Lorenzo Bertolini and
  • Susanna Esposito

Gaucher Disease (GD) is a condition resulting from an autosomal recessive inheritance pattern, characterized by a deficiency of the lysosomal enzyme beta-glucocerebrosidase. This leads to the accumulation of glucocerebroside and other glycolipids in...

  • Article
  • Open Access
2 Citations
2,579 Views
16 Pages

Obesity Risk Assessment for Spanish-Speaking Immigrant Families with Young Children in the United States: Reliability and Validity with Nutrient Values

  • Marilyn S. Townsend,
  • Mical K. Shilts,
  • Louise Lanoue,
  • Christiana Drake,
  • L. Karina Díaz Rios,
  • Nancy L. Keim,
  • Dennis M. Styne and
  • Lenna L. Ontai

The purpose is to examine validity and reliability for an obesity risk assessment tool developed in Spanish for immigrant families with children, 3–5 years old using an 8-week cross-sectional design with data collected over 1 year at Head Start...

  • Feature Paper
  • Article
  • Open Access
4 Citations
2,765 Views
13 Pages

The Benefit of a Retrospective Pregnancy Anamnesis in Child and Adolescent Psychiatry: The Reliability of Maternal Self-Report during Childhood Development

  • Stefan Mestermann,
  • Peter A. Fasching,
  • Matthias W. Beckmann,
  • Jennifer Gerlach,
  • Oliver Kratz,
  • Gunther H. Moll,
  • Johannes Kornhuber,
  • Anna Eichler and
  • the IMAC-Mind-Consortium

Pregnancy anamnesis is a crucial part of child and adolescent psychiatry diagnostics. In previous works, the reliability of retrospective maternal self-report on perinatal characteristics was heterogeneous. This prospective longitudinal study aimed t...

  • Article
  • Open Access
8 Citations
3,775 Views
15 Pages

The purpose of this study was to apply the Personal and Social Responsibility Model (TPSR) and verify its effects on responsibility and motivation according to educational stage. For this, teachers from Physical Education and other subjects were trai...

  • Article
  • Open Access
2,847 Views
14 Pages

Segregated by Wealth, Health, and Development: An Analysis of Pre-School Child Health in a Medium-Sized German City

  • Karoline Wagner,
  • Andreas Wienke,
  • Christine Gröger,
  • Jan-Henning Klusmann and
  • Amand Führer

The School Entry Examination (SEE) can be used to identify children with current health issues, developmental delays, and risk factors for later diseases. This study analyzes the health status of preschool children in a German city with considerable...

  • Case Report
  • Open Access
2,024 Views
9 Pages

Pediatric COVID-TB: A Clinical Perspective Based on the Analysis of Three Cases

  • Fabrizio Leone,
  • Martina Di Giuseppe,
  • Maia De Luca,
  • Laura Cursi,
  • Francesca Ippolita Calo Carducci,
  • Andrzej Krzysztofiak,
  • Sara Chiurchiù,
  • Lorenza Romani,
  • Cristina Russo and
  • Stefania Bernardi
  • + 1 author

Coronavirus disease 2019 (COVID-19) and tuberculosis (TB) are currently two major causes of death among infectious diseases. Active tuberculosis and a history of tuberculosis appear to be associated with an increased risk of COVID-19. This coinfectio...

  • Article
  • Open Access
7 Citations
6,768 Views
22 Pages

Secondary Prevention of Diabetes Type 1 with Oral Calcitriol and Analogs, the PRECAL Study

  • Dimitrios T. Papadimitriou,
  • Eleni Dermitzaki,
  • Panagiotis Christopoulos,
  • Maria Papagianni,
  • Kleanthis Kleanthous,
  • Chrysanthi Marakaki,
  • Anastasios Papadimitriou and
  • George Mastorakos

Screening for Type 1 Diabetes (T1D, incidence 1:300) with T1D autoantibodies (T1Ab) at ages 2 and 6, while sensitive, lacks a preventive strategy. Cholecalciferol 2000 IU daily since birth reduced T1D by 80% at 1 year. T1D-associated T1Ab negativized...

  • Review
  • Open Access
28 Citations
15,140 Views
32 Pages

Mindfulness-based interventions (MBIs) are growing in popularity, with research concerning their efficacy with youth populations. Following a preliminary analysis of the existing literature, and given the positive effects of such programs, we felt it...

  • Article
  • Open Access
1 Citations
1,942 Views
14 Pages

Perinatal Characteristics and the Sensitization to Cow Milk, Egg Whites and Wheat in Children up to 3 Years of Age

  • Hsin-Yu Chang,
  • Zon-Min Lee,
  • Ling-Sai Chang,
  • Wei-Ling Feng,
  • Yao-Hsu Yang and
  • Mei-Chen Ou-Yang

Food sensitization in early life identifies children at risk of developing allergic diseases. We investigated the sensitization to cow milk (CM), egg whites, and wheat. Newborns and infants under 3 years of age with available specific immunoglobulin...

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Children - ISSN 2227-9067