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Clocks & Sleep, Volume 7, Issue 1

2025 March - 16 articles

Cover Story: Fixed sleep schedules with 8 hours in bed (TIB) are commonly used to ensure that participants are well-rested before laboratory studies. However, such schedules may lead to cumulative sleep debt in young individuals, and the effects on older individuals are unclear. In the following study, we combine experimental data and modelling to quantify the impact of sleep debt on sleep propensity in young (20–31 years) and older (61–82 years) participants. Using a 40-hour multiple nap protocol, we show that despite fixed 8-hour TIB schedules, both age groups accumulate sleep debt, which dissipates within the first day of the protocol, highlighting important implications for protocol design in sleep research. View this paper
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Articles (16)

  • Brief Report
  • Open Access
1,598 Views
8 Pages

Sleep Timing Across the Lifespan of Australian Adults

  • Gabrielle Rigney,
  • Matthew Browne,
  • Charli Sargent and
  • Michele Lastella

The aim of this study was to examine sleep timing across the lifespan of Australian adults. A cross-sectional design was used to collect information on subjective sleep timing from 1225 participants (52.3% female) during a telephone interview. The pa...

  • Article
  • Open Access
1 Citations
4,016 Views
16 Pages

Mapping the Neural Basis of Wake Onset Regularity and Its Effects on Sleep Quality and Positive Affect

  • David Negelspach,
  • Kathryn E. R. Kennedy,
  • Alisa Huskey,
  • Jungwon Cha,
  • Anna Alkozei and
  • William D. S. Killgore

The regularity of sleep–wake cycles is a defining characteristic of normative sleep patterns that are typically associated with proper circadian rhythmicity. The previous literature indicates that consistent patterns of sleep and wake are assoc...

  • Article
  • Open Access
2 Citations
5,610 Views
19 Pages

Identifying Risk and Protective Factors for Shift Work Sleep Disorder: Insights from UK Biobank Night Shift Workers

  • Jürgen Degenfellner,
  • Susanne Strohmaier,
  • Magdalena Zebrowska,
  • Ingvild Saksvik-Lehouillier and
  • Eva Schernhammer

Shift Work Sleep Disorder (SWSD) is a significant and highly prevalent condition affecting up to 48% of individuals with irregular work schedules. The diagnostic criteria for SWSD include persistent insomnia or sleepiness in relation to shift work, n...

  • Article
  • Open Access
1 Citations
3,659 Views
20 Pages

Not All Workers Experience Equal Sleep Changes: Insights from the “WorkInCovid” Project

  • Sergio Garbarino,
  • Antonella Bodini,
  • Saverio Sabina,
  • Carlo Giacomo Leo,
  • Pierpaolo Mincarone,
  • Antonella Rissotto,
  • Stanislao Fusco,
  • Roberto Guarino,
  • Maria Rosaria Tumolo and
  • Nicola Magnavita
  • + 2 authors

The COVID-19 outbreak has changed work organization in favor of a working from home (WH) modality. We examined the association of WH during the pandemic with sleep health in workers of a public research organization. An online cross-sectional survey...

  • Article
  • Open Access
2 Citations
3,773 Views
15 Pages

This study examined the nature, severity, and predictors of cognitive complaints in patients referred for suspected obstructive sleep apnea (OSA). The sample included 127 patients classified as no OSA (AHI, apnea/hypopnea index < 5, N = 32), mild...

  • Review
  • Open Access
1 Citations
2,967 Views
15 Pages

Critical Review of the Methodological Shortcoming of Ambulatory Blood Pressure Monitoring and Cognitive Function Studies

  • Shahab Haghayegh,
  • Ramon C. Hermida,
  • Michael H. Smolensky,
  • Mili Jimenez Gallardo,
  • Claudia Duran-Aniotz,
  • Andrea Slachevsky,
  • Maria Isabel Behrens,
  • David Aguillon,
  • Hernando Santamaria-Garcia and
  • Kun Hu
  • + 3 authors

Growing evidence suggests that abnormal diurnal blood pressure rhythms may be associated with many adverse health outcomes, including increased risk of cognitive impairment and dementia. This study evaluates methodological aspects of research on bidi...

  • Article
  • Open Access
2,150 Views
13 Pages

Night Work and Social Jet Lag: Pathways to Arterial Stiffness?

  • Waléria D. P. Gusmão,
  • Aline Silva-Costa,
  • Victor M. Silva and
  • Claudia R. C. Moreno

Cardiovascular diseases are the leading cause of morbidity and mortality worldwide. These conditions, characterized by multifactorial etiology, are associated with arterial stiffness, and adequate sleep serves as a preventive factor. Professionals en...

  • Article
  • Open Access
3,158 Views
14 Pages

Isolated Rem Sleep Behavior Disorder: A Model to Assess the Overnight Habituation of Emotional Reactivity

  • Caterina Leitner,
  • Viviana Greco,
  • Francesca Casoni,
  • Penelope A. Lewis,
  • Luigi Ferini-Strambi and
  • Andrea Galbiati

(1) Background: Phasic events in rapid eye movement (REM) sleep are a core feature of isolated REM behavior disorder (iRBD), which is often associated with emotion dysregulation. This study explores the relationship between sleep and the overnight ha...

  • Article
  • Open Access
2 Citations
2,744 Views
13 Pages

Healthcare Burden and Productivity Loss Due to Narcolepsy in Sweden

  • Anna Giertz,
  • Johan Mesterton,
  • Tanja Jakobsson,
  • Stephen Crawford,
  • Somraj Ghosh and
  • Anne-Marie Landtblom

Background: Narcolepsy impacts both patients and society, yet there is limited data on its socioeconomic consequences. Methods: This retrospective longitudinal cohort study used pseudonymized patient-level data from Swedish registers and included nar...

  • Article
  • Open Access
3 Citations
11,488 Views
14 Pages

Circadian Rhythms, Regular Exercise, and Cognitive Performance in Morning-Trained Dancers

  • Mariana Marchesano,
  • Alejandra Carboni,
  • Bettina Tassino and
  • Ana Silva

Time-of-day and individual circadian variability influence cognitive performance, with later chronotypes being most compromised earlier in the day. On the other hand, moderate-intensity exercise has been shown to enhance cognitive function. We sought...

  • Article
  • Open Access
1,645 Views
15 Pages

Sleep Alterations in the Population of the Metropolitan Area of Mexico and Their Association with Lifestyle Changes During COVID-19 Confinement

  • María del Rosario Ayala-Moreno,
  • Paola Andrea Martínez-Serrano,
  • Montserrat Alheli Melgarejo-Gutiérrez,
  • Alma Rosa Hernández-Mondragón,
  • Azucena Martínez-Basila,
  • Araceli Martínez-Coronado,
  • María José Losana-Valencia,
  • Esther Vargas-Medina,
  • Eloisa Colín-Ramírez and
  • Adriana Benítez-Rico

Home confinement due to Coronavirus Disease 2019 (COVID-19) led to lifestyle changes that increased sleep disturbances, particularly in areas with higher infection and mortality rates. This study is a retrospective study based on data collected throu...

  • Article
  • Open Access
1 Citations
4,399 Views
14 Pages

Association Between Alcohol Use Patterns and Insomnia Symptoms or Poor Sleep Quality Among Adult Women: An Internet Cross-Sectional Survey in Japan

  • Suguru Nakajima,
  • Yuichiro Otsuka,
  • Yoshitaka Kaneita,
  • Osamu Itani,
  • Yuki Kuwabara,
  • Aya Kinjo,
  • Ruriko Minobe,
  • Hitoshi Maesato,
  • Susumu Higuchi and
  • Yoneatsu Osaki
  • + 5 authors

It is unclear whether patterns of alcohol consumption are associated with sleep disturbance. We aimed to investigate the relationship between comprehensive alcohol-related factors and insomnia symptoms, as well as sleep quality, among adult women in...

  • Article
  • Open Access
2,631 Views
20 Pages

Feasibility of an At-Home Experimental Circadian Misalignment Induction for Adolescents

  • Dean W. Beebe,
  • Andrea L. Fidler,
  • Laura McLaughlin,
  • Sabrina Grove and
  • Stephanie J. Crowley

Despite extensive research on the effects of sleep restriction on adolescent health, the field lacks experimental methods to study the health effects of mistimed sleep, which is also common among adolescents. This paper describes a novel 3-week exper...

  • Protocol
  • Open Access
1 Citations
4,827 Views
11 Pages

Sleep disruption and deprivation are epidemic problems in the United States, even among those without a clinically diagnosed sleep disorder. Military service members demonstrate an increased risk of insomnia, which doubles after deployment. This stud...

  • Article
  • Open Access
6,498 Views
16 Pages

Impact of Varying Sleep Pressure on Daytime Sleep Propensity in Healthy Young and Older Adults

  • Stella de Haan,
  • Marine Dourte,
  • Michele Deantoni,
  • Mathilde Reyt,
  • Marion Baillet,
  • Christian Berthomier,
  • Vincenzo Muto,
  • Gregory Hammad,
  • Christian Cajochen and
  • Svetlana Postnova
  • + 3 authors

Fixed sleep schedules with an 8 h time in bed (TIB) are used to ensure participants are well-rested before laboratory studies. However, such schedules may lead to cumulative excess wakefulness in young individuals. Effects on older individuals are un...

  • Article
  • Open Access
4 Citations
2,191 Views
18 Pages

Changes in the Spatial Structure of Synchronization Connections in EEG During Nocturnal Sleep Apnea

  • Maxim Zhuravlev,
  • Anton Kiselev,
  • Anna Orlova,
  • Evgeniy Egorov,
  • Oxana Drapkina,
  • Margarita Simonyan,
  • Evgenia Drozhdeva,
  • Thomas Penzel and
  • Anastasiya Runnova

This study involved 72 volunteers divided into two groups according to the apnea–hypopnea index (AHI): AHI>15 episodes per hour (ep/h) (main group, n=39, including 28 men, median AHI 44.15, median age 47), 0AHI15ep/h (control group,...

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Clocks & Sleep - ISSN 2624-5175