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Future Pharmacology, Volume 3, Issue 3

2023 September - 8 articles

Cover Story: The emerging opportunistic pathogen Mycobacterium abscessus is a bacterium primarily infecting the respiratory tract of individuals with pre-existing clinical conditions like chronic pulmonary diseases or cystic fibrosis. These infections exacerbate health issues and may even be lethal for those patients. The actual therapeutic regimen relies on a combination of repurposed drugs, and it is extended for long periods due to its low efficacy. This scenario underlines the urgency to improve the therapies through the development of new pathogen-specific drugs along with the exploration of alternative strategies. View this paper
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Articles (8)

  • Review
  • Open Access
4 Citations
3,875 Views
27 Pages

Moles of Molecules against Mycobacterium abscessus: A Review of Current Research

  • Mario Cocorullo,
  • Christian Bettoni,
  • Sara Foiadelli and
  • Giovanni Stelitano

Mycobacterium abscessus is an emerging opportunistic pathogen that infects mainly the respiratory tract of individuals with pre-existing clinical pictures. In recent years, the incidence of infections of this microorganism has risen, in particular in...

  • Article
  • Open Access
8 Citations
2,783 Views
12 Pages

Aurones as Antidiabetic Agents and Their Prebiotic Activities

  • Reham M. Samra,
  • Mohamed S. Darwish,
  • Noha A. Abou-Zeid,
  • Ebtihal Khojah,
  • Vincent O. Imieje and
  • Ahmed A. Zaki

Cyperus conglomeratus has been utilized in traditional medicine as an emollient, diuretic, analgesic, anthelmintic, and for other diseases. Furthermore, several biological activities have been reported for the plant extract and the isolated metabolit...

  • Article
  • Open Access
4 Citations
2,430 Views
13 Pages

Systemic Inflammasome Biomarkers as Predictors of Diabetic Retinopathy Progression: Evidence from a Pilot Study

  • Charisse Y.-J. Kuo,
  • Ilva D. Rupenthal,
  • Michael Booth,
  • Rinki Murphy and
  • Odunayo O. Mugisho

The nucleotide-binding oligomerization domain (NOD)-like receptor (NLR) protein 3 (NLRP3) inflammasome pathway is believed to mediate chronic inflammation in diabetic retinopathy (DR); however, its impact on the progression of DR remains to be elucid...

  • Review
  • Open Access
7 Citations
4,630 Views
15 Pages

Cyclodextrins, a family of cyclic oligosaccharides, have received considerable interest in the field of pharmaceuticals due to their unique molecular structure and versatile properties. In the context of vaccines, cyclodextrins can effectively encaps...

  • Review
  • Open Access
2 Citations
5,514 Views
11 Pages

Hereditary angioedema (HAE) is a rare, inherited disease caused by a deficiency (HAE-1) or lack of functional (HAE-2) C1 inhibitor protein. The symptoms present with mucocutaneous swelling of various organ systems, such as the respiratory and gastroi...

  • Article
  • Open Access
2 Citations
3,567 Views
17 Pages

Design of a Cyclodextrin Bioproduction Process Using Bacillus pseudofirmus and Paenibacillus macerans

  • Alexandre Miguel Guedes,
  • Tiago Filipe Santos Alves,
  • Paulo J. Salústio,
  • Helena M. Cabral-Marques and
  • Maria H. L. Ribeiro

Cyclodextrin (CD) drug delivery systems offer the potential to enhance the desired physicochemical properties and pharmacokinetic parameters of drugs while maintaining their safety. Cyclodextrin-glucosyl-transferase (CGTase) is amongst the most impor...

  • Review
  • Open Access
30 Citations
8,259 Views
33 Pages

The ‘post-antibiotic’ era is near according to the World Health Organization (WHO). It is well known, due to the work of the scientific community, that drugs (antibiotics, antifungals, and other antimicrobial agents) are continuously beco...

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Future Pharmacol. - ISSN 2673-9879