Disentangling the Association between Chronic Diseases and Oxidative Stress through Metabolomics
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 6617
Special Issue Editor
Interests: tumor metabolism for precision medicine in cancer; healthy aging; frailty and metabolic age; host- microbiota co-metabolism influence on health; cardiometabolic and cardiovascular disease; biophysical characterization of lipoproteins particles in plasma using NMR spectroscopy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Oxidative stress is the result of metabolic disbalance and can impact all components of the cell, including DNA, proteins, and metabolites. Many studies suggest an essential role of oxidative stress in the pathogenesis of chronic diseases, including cardiovascular diseases, diabetes, and neurodegenerative diseases. Studies analyzing the metabolic impact of oxidative stress on experimental models or human cohorts are scarce. Metabolomics provides information on a wide range of molecular processes through the measurement of individual metabolites. Metabolomics stands at the end of the -omic cascade (from genomics, transcriptomics, and proteomics to metabolomics), and changes in the metabolome represent the last response to genetic, chemical, and environmental alterations. As a consequence, the metabolome is closely linked to the phenotype and constitutes an important tool for detecting and understanding physiological and pathophysiological states. The goal of this Special Issue is to collect evidence and provide mechanistic insight to better understand the association between oxidative stress and chronic diseases through the analysis of metabolites.
Dr. Daniel Monleon
Guest Editor
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Keywords
- oxidative stress
- metabolomics
- chronic diseases
- cardiovascular disease
- diabetes
- neurodegenerative diseases
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