Oxidative Stress in Preterm Infants
A special issue of Antioxidants (ISSN 2076-3921).
Deadline for manuscript submissions: closed (29 February 2020) | Viewed by 4400
Special Issue Editor
Interests: pediatrics; intensive care; oxidative stress; antioxidants
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Oxidative stress is implicated in the pathogenesis of several pathologic conditions of the preterm newborn, commonly referred to as “oxygen radical diseases of neonatology” to underline the crucial role of oxidative stress in this wide range of neonatal morbidities. Advances in neonatal care, including resuscitation and ventilation support technology, have seen increased survival rates among premature neonates and a concomitant detection in the incidence of these free radicals-related diseases.
In order to counteract free radicals damage, many strategies to augment antioxidant status in preterm infants have been proposed, and several medications have been tested with mixed results. Melatonin is both a potent free radical scavenger and a broad-spectrum antioxidant. It also possesses the capability to modulate inflammation and increases mitochondrial biogenesis. Melatonin has an excellent biosafety profile and easily crosses the placenta and blood–brain barrier; therefore, due to its wide spectrum of properties, melatonin would appear to be a potentially beneficial molecule for therapeutic uses in the management of neonates with oxidative stress-related disorders. Several studies have tested the efficacy of melatonin in diseases of newborns such as chronic lung disease, perinatal brain injury, necrotizing enterocolitis, and retinopathy of prematurity, giving promising results.
We invite you to submit your latest research findings, both in vitro and in vivo studies, or a review article to this Special Issue, which will bring together current research concerning oxidative stress in preterm infants and the action that antioxidant therapies, such as melatonin, can play to counteract this oxidative damage.
We look forward to your contribution.
Prof. Dr. Eloisa Gitto
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Oxidative stress
- Prematurity
- Melatonin
- Neonatal intensive care
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.