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Dental Biomaterials: Evaluation and Clinical Applications
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Dental Biomaterials: Evaluation and Clinical Applications

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Dentistry and Oral Sciences".

Deadline for manuscript submissions: closed (31 March 2023) | Viewed by 4099

Special Issue Editor

Dr. Gustavo Fernandes

E-Mail Website
Guest Editor
Missouri School of Dentistry & Oral Health, A. T. Still University, St. Louis, MO 63104, USA
Interests: biomaterials; biocompatibility; soft tissue; connective tissue graft; PRF; autologous platelet concentration; osteoblasts; bone tissue engineering; bone grafts and related treatments; bone mineralization; tissue engineering; tissue regeneration; implant dentistry; scaffolds; calcium phosphates, hydroxyapatites; osteogenic differentiation; bioceramics; periodontics; oral surgery; biocompatible materials; biomimetic materials
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We would like to invite you to submit your research work to our Special Issue, “Dental Biomaterials: Evaluation and Clinical Applications”.

Continuous progress in the biomaterials field allows the development of new studies and methods to treat and rehabilitate patients. This applies to biomaterials used in restorative dentistry in children and adults, as well as materials used during prosthetic, orthodontic, surgical, and periodontal treatment. Research in the field of innovation and progress in the field of dental materials includes biomaterials for filling cavities and lost teeth and in the constantly developing field of micro- and nano-dentistry.

This Special Edition will focus on the achievements and evaluation that have been made since in vitro and in vivo applications (i.e., mechanical, antimicrobial, biological, chemical, and cytotoxic properties) until the clinical application of these materials, involving (i) experimental/innovative and commercially available biomaterials; (ii) dental tools, dental implants; (iii) the use of these materials and tools in the field of restorative and regenerative dentistry; (iv) and their application in therapeutic management in the field of preventive–restorative dentistry, periodontics, prosthetics, orthodontics, and oral surgery.

Authors conducting studies on these themes are welcome to submit original research articles, reviews, short communications, case series, and case reports.

Prof. Dr. Gustavo Fernandes
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • periodontics
  • dental implants
  • biomaterials
  • surgery
  • regenerative medicine
  • soft graft
  • tissue graft
  • bone graft
  • rehabilitation
  • dental implants
  • restorative dentistry
  • prosthetics
  • orthodontics

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Published Papers (2 papers)

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Research

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12 pages, 1569 KiB  
Article
Influence of Thermal and Mechanical Load Cycling on Fracture Resistance of Premolars Filled with Calcium Silicate Sealer
by Ahlam Smran, Mariam Abdullah, Norasmatul Akma Ahmad, Nassr AL-Maflehi and Abdulaziz Samran
Appl. Sci. 2023, 13(7), 4388; https://doi.org/10.3390/app13074388 - 30 Mar 2023
Cited by 2 | Viewed by 1693
Abstract
The aim of this study was to evaluate the aging effect of thermomechanical cyclic load on fracture resistance of lower premolars obturated with AH Plus and BioRoot RCS root canal sealers. Forty-eight single-rooted premolars teeth were instrumented with REVO-S files up to SU/0.06 [...] Read more.
The aim of this study was to evaluate the aging effect of thermomechanical cyclic load on fracture resistance of lower premolars obturated with AH Plus and BioRoot RCS root canal sealers. Forty-eight single-rooted premolars teeth were instrumented with REVO-S files up to SU/0.06 taper. The teeth were randomly assigned into 2 main groups (n = 24) according to the selected two root canal sealers (AH Plus or BioRoot RCS). All teeth were obturated using matching gutta-percha. Each main group were further divided into 3 subgroups (A, B and C) (n = 8). Group A acted as the negative control group (non-Thermomechanical aging). Whereas Group B and C were subjected first to thermal variations in a thermal cycling machine (7500 and 15,000 thermal cycles), then two different dynamic loading periods namely 3 × 105 and 6 × 105 in a masticatory simulator with a nominal load of 5 kg at 1.2 Hz which simulate approximately 1 ½ and 3 years of clinical function respectively. The roots were decoronated and fracture resistance were measured using a universal testing machine. After thermal-mechanical aging, BioRoot RCS showed significantly higher fracture resistance (p < 0.05) than AH Plus. As the thermal-mechanical cycles increased both AH Plus and BioRoot RCS exhibited a significant decrease in fracture resistance (p < 0.05). It could be concluded that thermomechanical aging had a significant impact on the outcome of the fracture resistance of AH Plus and BioRoot RCS. Full article
(This article belongs to the Special Issue Dental Biomaterials: Evaluation and Clinical Applications)
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Review

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20 pages, 1275 KiB  
Review
Effects of Melatonin in the Non-Surgical Treatment of Periodontitis: A Systematic Review
by Simone Purpura, Gustavo Vicentis Oliveira Fernandes, Filipa Pinto Oliveira and Filipe Correia de Castro
Appl. Sci. 2022, 12(22), 11698; https://doi.org/10.3390/app122211698 - 17 Nov 2022
Cited by 6 | Viewed by 1736
Abstract
Background: Melatonin is a hormone produced by the pineal gland, an endocrine gland located at the base of the brain. It acts as a powerful antioxidant; it can bring numerous advantages to periodontal diseases, pursuing homeostasis, such as restoration of the concentration of [...] Read more.
Background: Melatonin is a hormone produced by the pineal gland, an endocrine gland located at the base of the brain. It acts as a powerful antioxidant; it can bring numerous advantages to periodontal diseases, pursuing homeostasis, such as restoration of the concentration of antioxidants, reduction of periodontal inflammation with the regulation of inflammatory cytokines, reduction of oxidative stress, and significant reduction of bone resorption through the modulation of osteoclastic and osteoblastic activities. Then, the goal of this integrative review was to evaluate the literature to better understand whether the use of melatonin is feasible to improve the non-surgical treatment of periodontitis. Methods: The integrative review was based on PICO strategy and PRISMA methodology. The focus question was: “Are there significant benefits in applying melatonin for the non-surgical treatment of periodontitis?” The PubMed, B-On, and Cochrane Library databases were enrolled, using the keywords melatonin, periodontal therapy, non-surgical treatment, and periodontitis, as associated with the Boolean connectors. The inclusion criteria were (i) CCT or RCT, (ii) adult population, (iii) full-text articles available, and (iv) in the last 10 years (2012–2022). The exclusion criteria were (i) animal studies, (ii) systematic review, and (iii) no other languages than English, Spanish, Portuguese, and Italian. A risk of bias was performed to assess the articles. Results: Initially, 2705 articles were identified. However, only six articles were included. From a total of 228 patients (109F and 119M) diagnosed with periodontitis, 22 patients dropped out (9.65%). The follow-up period varied between 8 weeks, 3 months, and 6 months. For clinical and molecular parameters, the melatonin group had significant and greater improvement (intragroup) and better data than the control group, which also had favorable results. There was low risk of bias for all studies. Conclusions: Within the limitation of this study, melatonin is a reliable and feasible option as an adjunctive to the classical NSPT, obtaining a significative improvement of the periodontal parameters (PD, CAL, BOP, PI, and GI), a significative reduction of the pro-inflammatory proteins (IL-1b, IL-6, and TNF-α), and a better response for other biomarkers. Full article
(This article belongs to the Special Issue Dental Biomaterials: Evaluation and Clinical Applications)
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