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Brain Functional Connectivity: Prediction, Dynamics, and Modeling

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Neuroscience and Neural Engineering".

Deadline for manuscript submissions: 28 February 2025 | Viewed by 717

Special Issue Editor


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Guest Editor
Center for Biomedical Technology, Technical University of Madrid, Campus Montegancedo, Pozuelo de Alarcón, 28223 Madrid, Spain
Interests: complex systems; bioinformatics; mathematical and computational biology; optics and photonics; biological physics; cognitive neuroscience
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The brain is one of the most complex and mysterious systems in the world. Functional connectivity can be studied in both the frequency and time domains using methods such as coherence, correlation, and artificial neural networks. Revealing the functional connectivity between different brain regions can help us understand the mechanisms underlying information processing and decision making during cognitive tasks. This knowledge can also address practical and challenging problems in various fields, including healthcare, medicine, biomedical engineering, brain–machine interfaces, and cognitive sciences. The aim of this Special Issue is to collect the best papers on recent advances and perspectives in brain connectivity research, encompassing theoretical modeling, experimental studies, and the analysis of neurophysiological data obtained using various brain imaging modalities.

Prof. Dr. Alexander N. Pisarchik
Guest Editor

Manuscript Submission Information

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Keywords

  • neuroimaging data analysis
  • neurophysiological signal processing
  • brain dynamics
  • brain networks
  • brain modeling
  • brain deseases
  • connectomics
  • neuronal synchronization
  • brain–machine interface
  • cognitive neuroscience
  • deep learning in neuroscience

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Published Papers (1 paper)

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Research

27 pages, 3762 KiB  
Article
Multi-Graph Assessment of Temporal and Extratemporal Lobe Epilepsy in Resting-State fMRI
by Dimitra Amoiridou, Kostakis Gkiatis, Ioannis Kakkos, Kyriakos Garganis and George K. Matsopoulos
Appl. Sci. 2024, 14(18), 8336; https://doi.org/10.3390/app14188336 - 16 Sep 2024
Viewed by 410
Abstract
Epilepsy is a common neurological disorder that affects millions of people worldwide, disrupting brain networks and causing recurrent seizures. In this regard, investigating the distinctive characteristics of brain connectivity is crucial to understanding the underlying neural processes of epilepsy. However, the various graph-theory [...] Read more.
Epilepsy is a common neurological disorder that affects millions of people worldwide, disrupting brain networks and causing recurrent seizures. In this regard, investigating the distinctive characteristics of brain connectivity is crucial to understanding the underlying neural processes of epilepsy. However, the various graph-theory frameworks and different estimation measures may yield significant variability among the results of different studies. On this premise, this study investigates the brain network topological variations between patients with temporal lobe epilepsy (TLE) and extratemporal lobe epilepsy (ETLE) using both directed and undirected network connectivity methods as well as different graph-theory metrics. Our results reveal distinct topological differences in connectivity graphs between the two epilepsy groups, with TLE patients displaying more disassortative graphs at lower density levels compared to ETLE patients. Moreover, we highlight the variations in the hub regions across different network metrics, underscoring the importance of considering various centrality measures for a comprehensive understanding of brain network dynamics in epilepsy. Our findings suggest that the differences in brain network organization between TLE and ETLE patients could be attributed to the unique characteristics of each epilepsy type, offering insights into potential biomarkers for type-specific epilepsy diagnosis and treatment. Full article
(This article belongs to the Special Issue Brain Functional Connectivity: Prediction, Dynamics, and Modeling)
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