10th Anniversary of Biology—Innate Immune System: Insights from Zebrafish Models
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Immunology".
Deadline for manuscript submissions: closed (30 January 2023) | Viewed by 12992
Special Issue Editors
Interests: inflammation; cell death; host–pathogen interactions; inflammasomes; macrophages; live-imaging; zebrafish
Special Issue Information
Dear Colleagues,
The year 2021 marks the 10th anniversary of Biology, a peer-reviewed open access journal on biological sciences. Biology has published more than 1200 papers from more than 8300 authors. We are grateful to every author, reviewer, and academic editor whose support has made us where we are today.
To mark this significant milestone, a Special Issue entitled “10th Anniversary of Biology—Innate Immune System: Insights from Zebrafish Models” is being launched. The innate immune system plays a pivotal role in restoring homeostasis after stress, prominently in the defence against invading pathogens and healing of injured tissues. Cells of the innate immune system recognize and respond to danger signals in order to control infections and prompt tissue repair. Due to its fundamental role, defects in components of the innate immune system leading to insufficient or excessive activation usually result in disease.
In recent decades, the zebrafish has been consolidated as a powerful tool to model human diseases, to explore the mechanisms behind immune-caused diseases, and to dissect the dynamics of pathogenic infections. In fact, zebrafish models have greatly contributed to our knowledge of human infections that are difficult to replicate in mammalian hosts in vivo, as is the case of tuberculosis, which is well modelled in this animal.
This Special Issue aims to bring new research focused on the studies of the innate immune system using zebrafish models, as well as to consolidate and disseminate the state-of-the-art of the field via review articles. We encourage submissions of articles on topics that directly or indirectly affect the zebrafish as a preclinical model for immune diseases, such as tissue damage, inflammation and its resolution, and new tools and advances in genetic and imaging techniques that may translate into new insights on our knowledge of the vertebrate immune system.
Dr. Monica Varela
Dr. Gabriel Forn-Cuní
Guest Editors
Manuscript Submission Information
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Keywords
- zebrafish
- innate immunity
- macrophages
- neutrophils
- live imaging
- development
- infection
- tissue repair
- inflammation
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