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Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Bone Cell Biology

edited by Yohei Abe and

Giulia Lanzolla

submission deadline 31 Aug 2026 | 7 articles | Viewed by 21478 | Submission Open

Keywords: osteoclast; osteoblast; osteocyte; bone density; macrophage; RANK; transcription factor; cell signaling

(This special issue belongs to the Section Cell Biology)

Biology, Ecology and Management of Harmful Algae

edited by Paul V. Zimba and

Jabulani R. Gumbo

submission deadline 31 Aug 2026 | 8 articles | Viewed by 11733 | Submission Open

Keywords: harmful algae; toxic algae; harmful algal bloom (HAB); excessive algae growth; microalgae and macroalgae; cyanobacteria; dinoflagellates; toxins; water quality; phytoplankton; water resources

Editorial Board Members’ Collection Series: Pathology of Cancer and Cardiovascular Disease

edited by

Mridula Chopra

Helen L. Fillmore

and

Maurizio Forte

submission deadline 31 Aug 2026 | 3 articles | Viewed by 10420 | Submission Open

Keywords: cancer; cardiovascular disease; biomarkers; gut microbiome; inflammation; health policy; diet and lifestyle

Insecticide Resistance: Molecular Mechanisms and Ecological Implications

edited by Kaikai Mao

submission deadline 31 Aug 2026 | 1 articles | Viewed by 5524 | Submission Open

Keywords: insecticide resistance; molecular mechanism; regulatory network; ecological impact; non-target impact; resistance genes; pest resistance management

(This special issue belongs to the Section Ecology)

Lipid Metabolism in Plant Growth and Development

edited by Xiaohong Yu and Yingqi Cai

submission deadline 31 Aug 2026 | 3 articles | Viewed by 4961 | Submission Open

Keywords: lipid metabolism; lipid engineering; plant growth; plant development; lipid biosynthesis; lipid signaling; lipid transport; membrane structure; energy storage; plant– microbe interactions; stress response; nutrition value; cellular process

(This special issue belongs to the Section Plant Science)

Cellular and Molecular Biology of Liver Diseases

edited by Matthew McMillin

submission deadline 31 Aug 2026 | 1 articles | Viewed by 1958 | Submission Open

Keywords: drug-induced liver injury; cholestasis; hepatitis; metabolic dysfunction-associated steatotic liver disease; alcohol-associated liver disease

(This special issue belongs to the Section Cell Biology)

Advances in Leishmaniasis and Chagas Disease: Biology, Epidemiology, Treatment and Control (2nd Edition)

edited by

Fernando Almeida-Souza

Flávia de Oliveira Cardoso

and

Kátia Da Silva Calabrese

submission deadline 31 Aug 2026 | 1 articles | Viewed by 1871 | Submission Open

Keywords: leishmaniasis; Chagas disease; immunopathogeny; diagnosis; epidemiology; control; vaccine

Host–Microbiome–Environment Interactions in Domestic and Wild Animals

edited by

Cesar A. Rosales-Nieto

and Cesar A. Meza-Herrera

submission deadline 31 Aug 2026 | 1 articles | Viewed by 1699 | Submission Open

Keywords: animal microbiome; environmental microbiota; host– microbiota interactions; wildlife microbiology; livestock health and productivity; microbiome and conservation; One Health approach; gut microbiota dynamics; microbial ecology; microbiome and reproduction; habitat– host microbiome linkages; multi-omics integration

(This special issue belongs to the Section Microbiology)

Regenerative Biology: Regeneration After Spinal Cord and Peripheral Nerve Injury

edited by

Alexandre Leite Rodrigues de Oliveira

submission deadline 31 Aug 2026 | 1 articles | Viewed by 1514 | Submission Open

Keywords: neuronal regeneration; peripheral nerve repair; spinal cord injury; axonal growth; neuroplasticity; glial cells; molecular signaling pathways; stem cells in nerve regeneration; neuroinflammation; animal models of nerve injury

(This special issue belongs to the Section Neuroscience)

Bone Mechanics: From Cells to Organs, to Function

edited by

Viviana Toro-Ibacache

submission deadline 31 Aug 2026 | 2 articles | Viewed by 1511 | Submission Open

Keywords: bone mechanics; bone remodeling; mechanotransduction; structural analysis; functional morphology; bioengineering

(This special issue belongs to the Section Physiology)

Energy Metabolism, Genetics and Development in Drosophila

edited by

Do-Hwan Lim

submission deadline 31 Aug 2026 | 1 articles | Viewed by 591 | Submission Open

Keywords: Drosophila; energy metabolism; development; epigenetics; non-coding RNAs; metabolic disease; growth; signaling pathway

(This special issue belongs to the Section Bioinformatics)

Fruits and Seeds of Tropical Plants: Conservation of Species, Ecological Importance and Quality Valorization

edited by Edna Ursulino Alves and Silvanda De Melo Silva

submission deadline 31 Aug 2026 | 1 articles | Viewed by 505 | Submission Open

Keywords: climate change; nature conservation; biodiversity; plant propagation; postharvest quality; metabolic profile; orchard management and quality

(This special issue belongs to the Section Conservation Biology and Biodiversity)

Sickle Cell Disease: Molecular Mechanisms, Pathogenesis and Therapies

edited by Chithra Palani

submission deadline 31 Aug 2026 | Viewed by 434 | Submission Open

Keywords: SCD; anemia; erythrocyte development; erythroid progenitors; CD34 cells; vaso-occlusion; pain crisis; hemolysis; oxidative stress; sickling; inflammation; ER stress; fetal hemoglobin; hematopoiesis; ischemia and tissue damage; organ damage; drug development; SCD diagnosis; gene therapy; cell therapy

(This special issue belongs to the Section Medical Biology)

Microbiology and Metabolomics in Reproductive Biology

edited by

Giuseppina Campisciano

submission deadline 31 Aug 2026 | Viewed by 418 | Submission Open

Keywords: maternal microbiome; metabolome; pregnancy outcomes; fetal development; biomarkers; immune function; metabolic health; disease prediction; therapeutic interventions; maternal and child health

(This special issue belongs to the Section Developmental and Reproductive Biology)

Advances in Cardiac and Vascular Biology: From Mechanisms to Pathophysiology

edited by

Hanqiang Deng

and

Haodi Wu

submission deadline 31 Aug 2026 | Viewed by 353 | Submission Open

Keywords: cardiovascular biology; molecular mechanisms; cellular signaling; epigenomic regulation; vascular remodeling; metabolic reprogramming; cardiac pathophysiology

(This special issue belongs to the Section Physiology)

Mitochondrial Genomics of Arthropods

edited by Renfu Shao

submission deadline 31 Aug 2026 | 1 articles | Viewed by 311 | Submission Open

Keywords: mitochondrial genome architecture; transcriptional dynamics; translational mechanisms; comparative genomics; molecular evolution; arthropod phylogenetics; systematics; evolutionary biology

(This special issue belongs to the Section Genetics and Genomics)

Biophysics of Exposome: Molecular Mechanisms of Action

edited by

Judith Klein-Seetharaman

and Madhavi K. Ganapathiraju

submission deadline 31 Aug 2026 | Viewed by 226 | Submission Open

Keywords: computational biology; systems biology; mass spectrometry; protein– ligand networks; protein– protein interaction networks; metabolomics; proteomics; surface plasmon resonance; protein structure prediction; molecular docking; target fishing; machine learning; artificial intelligence

Current Status and Future Perspectives on Lipid Biology and Beyond

edited by

Jasmina Debeljak Martacic

and

Slavica Ranković

submission deadline 31 Aug 2026 | Viewed by 214 | Submission Open

Keywords: lipids; fatty acids (FAs); omega-3 (FA); omega-6 (FA); cancer; cell biology; oxylipins; oxidative stress; lipidomics; lipid nanoparticles; personalized lipid-based therapies

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Research Progress on Metabolic Pathways in Neurodegenerative Diseases

edited by Ali H. Rafati

submission deadline 31 Aug 2026 | Viewed by 156 | Submission Open

Keywords: neurodegeneration; metabolic dysfunction; mitochondrial impairment; oxidative stress; glucose metabolism; lipid metabolism; autophagy; neuroinflammation; biomarkers; therapeutic targets

(This special issue belongs to the Section Neuroscience)

Novel Mechanisms and Biological Processes in Redox and Inflammatory Signaling

edited by Shengchen Wang and

Demin Cai

submission deadline 31 Aug 2026 | Viewed by 137 | Submission Open

Keywords: redox; inflammatory; oxidative stress; antioxidant; anti-inflammatory; signaling pathways

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Biological Invasions in Freshwater Ecosystems

edited by Filipe Banha

submission deadline 31 Aug 2026 | Viewed by 117 | Submission Open

Keywords: invasive species; rivers; lakes; ecology; biology; impacts

(This special issue belongs to the Section Conservation Biology and Biodiversity)

Biogenesis and Function of Centrioles, Centrosomes, and Primary Cilia in Health and Disease

edited by

Ramona Lattao

and

Hélène Rangone

submission deadline 31 Aug 2026 | Viewed by 108 | Submission Open

Keywords: centriole; centrosome; cilia

(This special issue belongs to the Section Cell Biology)

Perception in Noise: From Human Perceptive Abilities to Neural Correlates and Computational Models

edited by

Jean Marc Edeline

submission deadline 31 Aug 2026 | Viewed by 84 | Submission Open

Keywords: auditory perception; neural networks; communication sounds; auditory system; masking noise; coding in noise; robust representation

(This special issue belongs to the Section Neuroscience)

Uncovering the Role of T Cells in Immune Homeostasis and Immune Tolerance

edited by

Yohei Sato

submission deadline 31 Aug 2026 | Viewed by 65 | Submission Open

Keywords: regulatory T cells; immune tolerance; FOXP3; cytokine; suppression

(This special issue belongs to the Section Cell Biology)

Environmental Factors and Freshwater Organism Responses

edited by

Christina Tadiri

and Joana L. Santos

submission deadline 31 Aug 2026 | Viewed by 47 | Submission Open

Keywords: freshwater ecosystems; environmental stressors; climate change; pollution; ecotoxicology; adaptation; phenotypic plasticity; biodiversity; conservation; genomics

(This special issue belongs to the Section Ecology)

Biosynthesis of Metabolites from Microorganisms, or Microorganism-Host Interaction? (Volume II)

edited by

Fengli Zhang

Zhiqiang Liu

and

Michel Denis

submission deadline 1 Sep 2026 | 7 articles | Viewed by 20303 | Submission Open

Keywords: biosynthesis; biological activity; biosynthesis regulation; microbial metabolites; microbe– host reaction

(This special issue belongs to the Section Microbiology)

Viral Infections in Animals: Pathogenesis and Immunity

edited by

Yang Li

submission deadline 1 Sep 2026 | 1 articles | Viewed by 2144 | Submission Open

Keywords: virus– host interactions; antiviral immunity; mechanisms of viral pathogenesis

(This special issue belongs to the Section Immunology)

Latest Discoveries in Non-Model Organisms and Non-Translational Biology

edited by

Malgorzata Kloc

and

Jacek Z. Kubiak

submission deadline 8 Sep 2026 | Viewed by 213 | Submission Open

Keywords: basic biological research; non-translational biology; non-clinical biology; fundamental science; non-model organisms; model organisms; scientific curiosity– driven research; biological diversity; experimental biology; theoretical biology

Feature Papers on Developmental and Reproductive Biology

edited by

Jacek Z. Kubiak

submission deadline 15 Sep 2026 | 13 articles | Viewed by 32839 | Submission Open

Keywords: embryo/fetus development; reproductive biology; gametogenesis; differentiation; growth; homeostasis; regeneration; aging; cell cycle regulation; stem cells; organoids

(This special issue belongs to the Section Developmental and Reproductive Biology)

Molecular and Cellular Mechanisms of Neuroinflammation and Chronic Pain

edited by Mario Garcia-Dominguez

submission deadline 15 Sep 2026 | Viewed by 82 | Submission Open

Keywords: neuroinflammation; chronic pain; neuroimmune interactions; glial activation; cytokine signaling; synaptic plasticity; oxidative stress; epigenetic regulation; microglia and astrocytes; therapeutic targets

(This special issue belongs to the Section Neuroscience)

Plant Breeding: From Biology to Biotechnology

edited by Juwu Gong

submission deadline 30 Sep 2026 | 5 articles | Viewed by 9413 | Submission Open

Keywords: plant breeding; biotechnology; molecular marker-assisted selection; genetic engineering; genome editing; tissue culture; phenotype; genetics; omics

(This special issue belongs to the Section Biotechnology)

Signalling Pathways in Cancer and Disease

edited by

Ahmed Elbediwy

and

Nadine Wehida

submission deadline 30 Sep 2026 | 5 articles | Viewed by 7791 | Submission Open

Keywords: cancer; signalling; metastasis; tumorigenesis; cancer targeting

(This special issue belongs to the Section Cancer Biology)

Large Animal Experimental and Epidemiological Models for Diseases

edited by

Witaya Suriyasathaporn

and

Sho Nakamura

submission deadline 30 Sep 2026 | 4 articles | Viewed by 6347 | Submission Open

Keywords: large animal model; dog; pig; ruminants; experimental study; epidemiological study; infectious diseases; non-infectious diseases; treatment; disease control; disease prediction

(This special issue belongs to the Section Medical Biology)

Molecular Basis of Bone Homeostasis and Skeletal Diseases

edited by

Weirong Xing

submission deadline 30 Sep 2026 | 3 articles | Viewed by 6064 | Submission Open

Keywords: osteoclast; osteoblast; bone; skeletal disease; bone formation; bone resorption; osteoporosis; osteopetrosis; human genetics; mouse genetics

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Research Advancements in Oral Biology

edited by

Jelena R. Roganović

and Nina Petrović

submission deadline 30 Sep 2026 | 3 articles | Viewed by 5749 | Submission Open

Keywords: oral biology; oral tissue regeneration; artificial intelligence (AI) in dentistry; genomics and proteomics in dentistry; dental research; salivary diagnostics

(This special issue belongs to the Section Medical Biology)

Experimental Biology, Life Science and One Health: From Basic to Translational Research

edited by

Francesco Cappello

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2901 | Submission Open

Keywords: anatomy; histology; embryology; aquatic environment and ecosystem; biotechnology and bioengineering; cell stress; environment and health; extracellular vesicles; fight against cancer; movement and nutrition science; neuroscience; plant ecology and ecosystem; regenerative biomedicine

Advances in Animal Functional Genomics

edited by Chugang Mei

submission deadline 30 Sep 2026 | 3 articles | Viewed by 2527 | Submission Open

Keywords: functional genomics; gene editing; phenomics; epigenetics; livestock; conservation; CRISPR; host– microbiome interactions

(This special issue belongs to the Section Zoology)

The Role of Innate Immunity in Organ Transplantation

edited by Todd V. Brennan

submission deadline 30 Sep 2026 | 1 articles | Viewed by 2213 | Submission Open

Keywords: innate immunity; allograft rejection; transplantation; immune tolerance

(This special issue belongs to the Section Medical Biology)

Detection of Parasites and Parasitic Diseases in Animals

edited by

Bogumila Pilarczyk

and Agnieszka Tylkowska

submission deadline 30 Sep 2026 | Viewed by 679 | Submission Open

Keywords: parasitic infections; parasitic diseases; veterinary diagnostics; molecular techniques; epidemiology; zoonoses; host-parasite interactions; antiparasitic therapies; wildlife health; preventive programs

(This special issue belongs to the Section Zoology)

Molecular Mechanisms of Cell Signal Transduction

edited by

Wenjing Zhang

submission deadline 30 Sep 2026 | Viewed by 567 | Submission Open

Keywords: molecular interactions in signaling; phosphorylation and signal propagation; post-translational modifications; cross-talk between signaling pathways; cellular response to extracellular stimuli; metabolic regulation and signaling; signaling in cancer progression; inflammatory signaling pathways; role of signaling in stem cell differentiation; innovative imaging techniques for signaling

(This special issue belongs to the Section Cell Biology)

Physiology and Ecology of Animal Parasites and Related Diseases

edited by Marcela K. Castelo

submission deadline 30 Sep 2026 | Viewed by 455 | Submission Open

Keywords: parasites; parasitoids; physiology; ecology; ecophysiology; diseases; global change

(This special issue belongs to the Section Zoology)

More than a Shield: The Secret Functions of Epithelial Cells in Homeostasis and Infections

edited by

Mohamed Ibrahem Elhawy

and Na Zhao

submission deadline 30 Sep 2026 | Viewed by 317 | Submission Open

Keywords: epithelial diversity; signaling; homeostasis; immunity; infection; microbiome; inflammation; cytokines; antimicrobial peptides

(This special issue belongs to the Section Medical Biology)

Gut Microbiome in Health and Disease (3rd Edition)

edited by

Hao Zhong

and

Fengqin Feng

submission deadline 30 Sep 2026 | Viewed by 180 | Submission Open

Keywords: gut microbiota; ‘ gut– X’ axis; dysbiosis; food nutrition; metabolites; type 2 diabetes mellitus; gut health; immunity

(This special issue belongs to the Section Microbiology)

Environmental and Hormonal Modulators of Cell Fate: Epigenetic and Phenotypic Plasticity in Somatic Tissues

edited by Alireza R. Fazeli and

Małgorzata Duda

submission deadline 30 Sep 2026 | Viewed by 164 | Submission Open

Keywords: cell fate; epigenetic regulation; phenotypic plasticity; hormonal signaling; environmental stressors; endocrine disruptors; somatic tissues; senescence; reprogramming; non-coding

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Molecular Mechanisms of Retina Development and Degeneration

edited by

Hélène Léger

submission deadline 30 Sep 2026 | Viewed by 158 | Submission Open

Keywords: retina; retinal development; retinal degeneration; molecular mechanisms; signaling pathways; genetic regulation; epigenetics; neuronal and glial interactions; neuroinflammation

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Bone Physiology and Development

edited by

Silviya Nikolova

Diana Toneva

and Yohei Abe

submission deadline 30 Sep 2026 | Viewed by 155 | Submission Open

Keywords: osteology; osteogenesis; bone growth; bone physiology; bone morphology; bone pathology; bone imaging

(This special issue belongs to the Section Physiology)

The Molecular and Cellular Mechanisms of Lung Injury and Recovery

edited by Weiguo Chen, HongLong Ji and Ibra S. Fancher

submission deadline 30 Sep 2026 | Viewed by 127 | Submission Open

Keywords: acute lung injury; chronic lung injury; ARDS; fibrosis; allergy; mechanisms; therapy; infection; inflammation; endothelial barrier

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Antibiotic Resistance Mechanisms: Ecological Implications

edited by

Fernando Baquero

submission deadline 30 Sep 2026 | Viewed by 108 | Submission Open

Keywords: antibiotic resistance in environmental bacteria; antibiotics in the environment; ecological consequences of antibiotic resistance; antibiotic synergies and antagonisms with environmental pollutants; biomarkers of antibiotic resistance in the environment

(This special issue belongs to the Section Microbiology)

Cytogenetics and Cytogenomics in Insects

edited by

Denilce Meneses Lopes

Pedro Lorite Martínez

and

Pablo Mora

submission deadline 30 Sep 2026 | Viewed by 84 | Submission Open

Keywords: insects; chromosomes; cytogenomics; next generation; cytogenetics

(This special issue belongs to the Section Genetics and Genomics)

Pathogenic Mechanisms Involved in Development and Progression of ROS-Associated Diseases

edited by

Hye-Jin Park

submission deadline 30 Sep 2026 | Viewed by 82 | Submission Open

Keywords: Reactive Oxygen Species (ROS); oxidative stress; pathogenic mechanisms; disease progression; mitochondrial dysfunction; inflammation and immune regulation; redox biology; molecular signaling pathways; antioxidants and therapeutics; comparative medicine; One Health; translational research

(This special issue belongs to the Section Biochemistry and Molecular Biology)

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