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Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Plant Perception, Behavior, and Environmental Response Mechanisms

edited by

Silvia Guerra

and Bianca Bonato

submission deadline 15 Jul 2026 | Viewed by 62 | Submission Open

Keywords: plant perception; plant movement; social cognition; communication; plant behavior; climbing plants; interactions; plant– plant interactions; environment; plant– environment interactions

(This special issue belongs to the Section Plant Science)

Methods in Bioinformatics and Computational Biology

edited by

Xingjian Chen

submission deadline 25 Jul 2026 | 1 articles | Viewed by 695 | Submission Open

Keywords: bioinformatics; computational biology; machine learning in biomedicine; artificial intelligence; single-cell and spatial transcriptomics analysis; biological network analysis; high-throughput data analysis

Tissue and Organ Regeneration in Fish: Evolutionary Mechanisms

edited by Yujun Liang

submission deadline 30 Jul 2026 | 1 articles | Viewed by 5072 | Submission Open

Keywords: organ and tissue regeneration; regeneration mechanisms; progenitor cells; dedifferentiation; fishes; evolutionary adaptation; genetic regulation; signaling pathways; comparative genomics

(This special issue belongs to the Section Evolutionary Biology)

Plant Natural Products: Mechanisms of Action for Promoting Health

edited by

Francisco Les

and

Guillermo Cásedas

submission deadline 31 Jul 2026 | 12 articles | Viewed by 32956 | Submission Open

Keywords: phytochemicals; bioactivity; therapeutics; mechanisms; health promotion; metabolism; enzyme activity; bioactive compounds; pharmacognosy; plant extracts; polyphenols; ethnopharmacology; essential oils; aromatic plants; antioxidants; natural products

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Dendrochronology in Arid and Semiarid Regions

edited by

Zongshan Li

submission deadline 31 Jul 2026 | 6 articles | Viewed by 13920 | Submission Open

Keywords: tree rings; growth– climate response; dendrochronology; dendroecology; dryland regions

(This special issue belongs to the Section Ecology)

Animal Models of Metabolic Diseases

edited by

Júlio Cezar De Oliveira

and

Melvin Khee Shing Leow

submission deadline 31 Jul 2026 | 7 articles | Viewed by 13036 | Submission Open

Keywords: experimental models; metabolic syndrome; insulin resistance; type 2 diabetes mellitus; obesity; dyslipidemia; hypertension; metabolic programming; DOHaD

(This special issue belongs to the Section Physiology)

Reproductive Physiology and Pathology in Livestock

edited by Claudio Gustavo Ustavo Barbeito and

Fabiano José Ferreira De Sant’Ana

submission deadline 31 Jul 2026 | 5 articles | Viewed by 8566 | Submission Open

Keywords: livestock; animal reproduction; reproductive biology; physiology and pathology of reproduction; experimental models; non-conventional species; biotechnology; immunology

(This special issue belongs to the Section Developmental and Reproductive Biology)

Phytoplasmas: Molecular Characterization and Host–Pathogen Interactions (2nd Edition)

edited by

Wei Wei

submission deadline 31 Jul 2026 | 5 articles | Viewed by 7835 | Submission Open

Keywords: molecular diagnosis and epidemiology; host-phytoplasma interactions; genetic diversity; taxonomy and classification; ecology and evolution; insect vectors; disease management; phytoplasma genomics and other omics studies

(This special issue belongs to the Section Microbiology)

Human Leukocyte Antigen (HLA)—Antigen Interactions in Vaccine Development

edited by

Apostolos P. Georgopoulos

submission deadline 31 Jul 2026 | 5 articles | Viewed by 7815 | Submission Open

Keywords: HLA; vaccine; antigen; antibody; cancer; binding affinity; biophysical modeling; lymphocytes

Ecological Regulation of Forest and Grassland Pests

edited by

Dun Wang

and Liangjian Qu

submission deadline 31 Jul 2026 | 6 articles | Viewed by 7308 | Submission Open

Keywords: forest and grassland pests; ecological regulation; sustainable IPM; biological control; forest management

(This special issue belongs to the Section Ecology)

Unraveling the Molecular Mechanisms of Development and Stress Tolerance in Vegetables

edited by

Zhansheng Li

Jin Xu

and

Ying Li

submission deadline 31 Jul 2026 | 3 articles | Viewed by 7299 | Submission Open

Keywords: vegetable development; molecular mechanisms; stress tolerance; genetic regulation; epigenetic regulation; biochemical regulation; sustainable agriculture; environmental stress; growth adaptation; crop yield; gene editing; cellular engineering

(This special issue belongs to the Section Plant Science)

Milk Oligosaccharides: Biological Functions and Application Prospects

edited by

Chunsheng Jin

submission deadline 31 Jul 2026 | 3 articles | Viewed by 7050 | Submission Open

Keywords: milk oligosaccharides; colostrum; HMO; gut microbiota; immune modulator; prebiotics

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Unraveling the Tumor-Immune Microenvironment Using Transcriptomics

edited by

Leonardo Oliveira Reis

submission deadline 31 Jul 2026 | 3 articles | Viewed by 6576 | Submission Open

Keywords: tumor-immune microenvironment; immune cells; tumor cells; stromal cells; signaling molecules; extracellular matrix (ECM); vascular network

(This special issue belongs to the Section Cancer Biology)

The Biodiversity and Ecosystem Dynamics of Deep-Sea Hydrothermal Vents

edited by

Xiang Zeng

and Yadong Zhou

submission deadline 31 Jul 2026 | 4 articles | Viewed by 6255 | Submission Open

Keywords: deep-sea hydrothermal vents; biodiversity; microbiome; biological resources; marine biology

(This special issue belongs to the Section Marine and Freshwater Biology)

The Relationship Between Water Quality and Aquatic Organisms (2nd Edition)

edited by Dong Zhang,

Ming Duan

Miao Wang

Xiangsheng Hong

and Mengmeng Yi

submission deadline 31 Jul 2026 | 4 articles | Viewed by 6196 | Submission Open

Keywords: aquatic animals; water quality; phytoplankton; zooplankton; microorganisms; physiology

Cellular and Molecular Mechanisms in Sensory–Metabolic Integration: From Signaling Pathways to Systemic Regulation

edited by

Antonino Maniaci

, Giovanni Giurdanella, Mohamed Amin Zaoual and

Caterina Gagliano

submission deadline 31 Jul 2026 | 3 articles | Viewed by 5288 | Submission Open

Keywords: multisensory disorders; metabolic dysfunction; systemic health; sensory impairments; metabolic syndrome; neurometabolic pathways; vision impairment; hearing loss; vestibular disorders; olfactory dysfunction; gustatory dysfunction; somatosensory impairment; energy homeostasis; integrative medicine

(This special issue belongs to the Section Biochemistry and Molecular Biology)

The Future of Marine Megafauna

edited by

Vincent L. Bels

and

John R. Turner

submission deadline 31 Jul 2026 | 3 articles | Viewed by 4410 | Submission Open

Keywords: marine biodiversity; marine megafauna; anthropogenic impacts; conservation biology; marine ecosystems; behavioural ecology; marine protected areas (MPAs); ecological resilience; evolutionary biology; species recovery strategies

(This special issue belongs to the Section Zoology)

Osteoblast Differentiation in Health and Disease

edited by

Nadia Calabriso

and Maria Annunziata Carluccio

submission deadline 31 Jul 2026 | 3 articles | Viewed by 3603 | Submission Open

Keywords: osteogenesis; mesenchymal stem cells; osteoblast; osteoblast differentiation; bone diseases; transcription factors; epigenetics; extracellular vesicles; inflammatory mediators; bioactive natural compounds

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Tickborne Diseases and Their Vectors

edited by Moses Sibusiso Mtshali

submission deadline 31 Jul 2026 | 2 articles | Viewed by 2458 | Submission Open

Keywords: ticks; tickborne pathogens; epidemiology of tickborne diseases; zoonotic diseases; molecular diagnosis; genetic diversity; immunology; vector control and mapping

(This special issue belongs to the Section Infection Biology)

2nd Edition: Conservation and Evolution of Wildlife in the Context of Climate Change and Human Population Growth

edited by

Wen Bo Liao

submission deadline 31 Jul 2026 | 3 articles | Viewed by 2449 | Submission Open

Keywords: changes; local temperature; adaptation; evolution; animals; plants

(This special issue belongs to the Section Behavioural Biology)

Advances in Redox Metabolism and Cellular Homeostasis

edited by

Alexios Vlamis-Gardikas

and

Jianqiang Xu

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1913 | Submission Open

Keywords: oxidative stress; peroxiredoxins; hydrogen peroxide; redox regulation; thiol modification; reactive oxygen species; iron sulfur clusters; redox signaling

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Advances in Microbial Enzyme Engineering

edited by

Thanongsak Chaiyaso

and Kamon Yakul

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1561 | Submission Open

Keywords: microbial enzyme engineering; lignocellulolytic enzymes; biorefinery applications; protein engineering; enzyme-based biomass conversion; synthetic biology

(This special issue belongs to the Section Microbiology)

Advances in Foodborne Pathogens

edited by Qiming Chen

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1120 | Submission Open

Keywords: foodborne pathogens; contamination mechanisms; infection mechanisms; detection assays; risk assessment; antibacterial agents or materials

(This special issue belongs to the Section Microbiology)

Heavy Metal Pollution and Bioremediation: Application and Mechanism

edited by

Guangxu Zhu

, Ruiyu Lin and Rongfei Wei

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1035 | Submission Open

Keywords: heavy metal pollutants; microbial remediation; phytoremediation; animal remediation; plant– soil– microbe interactions; enhanced remediation; combined remediation; hyperaccumulator plants; microbial-induced calcium carbonate precipitation

(This special issue belongs to the Section Toxicology)

Reprogramming Life: Synthetic Biology Approaches for Next-Gen Strain Engineering

edited by Thanaporn Laothanachareon,

Chitwadee Phithakrotchanakoon

and

Nunthaphan Vikromvarasiri

submission deadline 31 Jul 2026 | Viewed by 412 | Submission Open

Keywords: synthetic biology; strain engineering; metabolic pathway redesign; CRISPR/Cas genome editing; microbial cell factories; multi-omics integration; AI-driven metabolic design; sustainable bioproduction

(This special issue belongs to the Section Biotechnology)

Advances in Plant Genomics and Genome Editing

edited by Xuean Cui

submission deadline 31 Jul 2026 | 1 articles | Viewed by 392 | Submission Open

Keywords: plant genomes; plant genomics; genome sequencing; plant genome engineering; CRISPR/Cas; gene knock-out; gene knock-in; base editor; prime editor; genome editing tools; multiplex genome editing; gene expression regulation; plant trait improvement

(This special issue belongs to the Section Genetics and Genomics)

Mode of Action of Allelopathic Compounds

edited by

Agnieszka Gniazdowska

and Paweł Staszek

submission deadline 31 Jul 2026 | Viewed by 279 | Submission Open

Keywords: metabolomics; phytotoxic potential; mode of action; sustainable bioherbicides; root exudates; plant– plant interaction; plant– microbe interaction; metabolic malformations; biosynthesis of allelochemicals

(This special issue belongs to the Section Plant Science)

Exploring the Role of Serotonin in Psychiatric Disorders

edited by

Georgianna Gould

submission deadline 31 Jul 2026 | Viewed by 255 | Submission Open

Keywords: diet; drug treatments; enzymes; epigenetic; post translational modification; serotonin metabolism; serotonin receptors; serotonin transporters

(This special issue belongs to the Section Neuroscience)

Environmental and Nutritional Stress: Metabolic Consequences and Regulatory Strategies in Animals

edited by

Wenqiang Ma

submission deadline 31 Jul 2026 | Viewed by 146 | Submission Open

Keywords: stress physiology; metabolic dysfunction; environmental stress; nutritional stress; gut microbiota; bioactive compounds

(This special issue belongs to the Section Physiology)

Epilepsy: The Mechanisms of Seizure, Termination, and Biomarker Development

edited by

Keisuke Maeda

submission deadline 31 Jul 2026 | Viewed by 134 | Submission Open

Keywords: epilepsy; epileptogenesis; seizure mechanisms; seizure dynamics; termination; biomarkers; neural excitability; neuroscience

(This special issue belongs to the Section Neuroscience)

Animal Cognition and Decision Strategies: From Behaviour to Computation

edited by

HaDi MaBouDi

and

Alice Bridges

submission deadline 31 Jul 2026 | Viewed by 97 | Submission Open

Keywords: animal models; bio-inspired computation; brain– behaviour mapping; cognitive mechanisms; cognitive neuroscience; cognitive strategies; comparative cognition; computational modelling; decision-making; learning and adaptation; naturalistic behaviour; neural computation; neuroethology

(This special issue belongs to the Section Neuroscience)

CRISPR-Engineered Mouse Models for Unraveling Rare Diseases

edited by

Manuel A. Sanchez-Martin

submission deadline 31 Jul 2026 | Viewed by 68 | Submission Open

Keywords: mouse models; CRISPR/Cas9; rare disease modeling; phenotyping; translational research; svatar mice

(This special issue belongs to the Section Medical Biology)

Regulation of Gene Expression in Immune Cell Development and Function

edited by Bon Quy Trinh

submission deadline 31 Jul 2026 | Viewed by 67 | Submission Open

Keywords: noncoding RNA; enhancer; silencer; transposable element; epigenetics; chromatin structure and architecture; innate immunology; adaptive immunology; development; functions

(This special issue belongs to the Section Immunology)

Aquatic Alien Invasions and Their Impact on Biodiversity and Ecosystem Services—3rd Edition

edited by

Giorgio Mancinelli

Paraskevi K. Karachle

Elena Tricarico

and

Baran Yoğurtçuoğlu

submission deadline 31 Jul 2026 | Viewed by 50 | Submission Open

Keywords: species; aquatic invasions; biodiversity; ecosystem services; conservation

(This special issue belongs to the Section Marine and Freshwater Biology)

Applications of Gene Expression Profiling in Human Disease

edited by

Lipei Shao

submission deadline 31 Jul 2026 | Viewed by 46 | Submission Open

Keywords: gene expression profile; biomarkers; cancer; complex disease

(This special issue belongs to the Section Genetics and Genomics)

Ferroptosis: Mechanisms and Human Disease

edited by Chan-Yen Kuo

submission deadline 15 Aug 2026 | 4 articles | Viewed by 8984 | Submission Open

Keywords: ferroptosis; systemic diseases; inflammatory response; mitochondrial-dependent redox homeostasis; microenvironment

(This special issue belongs to the Section Cell Biology)

Changing Coral Reef Biodiversity and Function in the Anthropocene

edited by

Morgan Pratchett

submission deadline 15 Aug 2026 | Viewed by 386 | Submission Open

Keywords: anthropogenic stressors; coral reefs; climate change; biodiversity loss; marine conservation; ecological adaptation; ecosystem function; resilience

(This special issue belongs to the Section Marine and Freshwater Biology)

Role of CARD9 in Health and Diseases

edited by Zuberwasim Sayyad and Nikhil Sharma

submission deadline 15 Aug 2026 | Viewed by 134 | Submission Open

Keywords: CARD9; innate immunity; pattern recognition receptors; autophagy; apoptosis; inflammasome; reactive oxygen species; post-translational modifications; gut microbiota; inflammation and cancer

Recent Advances in Angiogenesis and Vascular Development

edited by

Concetta Scimone

and

Rosalia D’Angelo

submission deadline 15 Aug 2026 | Viewed by 36 | Submission Open

Keywords: vasculogenesis; angiogenesis; vascular differentiation markers; endothelial-to-mesenchymal transition (EndMT); mechanotransduction; endothelial function; endothelial damage

(This special issue belongs to the Section Cell Biology)

The Role of Autophagy and Macrophages in Modulating Immune Responses in Atherosclerosis

edited by

Kumar Prabhash Jha

and Aatira Vijay

submission deadline 25 Aug 2026 | Viewed by 137 | Submission Open

Keywords: atherosclerosis; macrophages; autophagy; immune regulation; chronic inflammation; plaque stability; lipid metabolism; efferocytosis; immunometabolism

Population Genetics and Conservation of Amphibians and Reptiles

edited by

Fang Yan

submission deadline 25 Aug 2026 | Viewed by 94 | Submission Open

Keywords: conservation genetics; local adaptation; genetic diversity; amphibian; reptile; environmental change

(This special issue belongs to the Section Conservation Biology and Biodiversity)

Animal Models of Arthritis

edited by Nevena Arsenović-Ranin and Biljana Bufan

submission deadline 30 Aug 2026 | 4 articles | Viewed by 11006 | Submission Open

Keywords: animal models; rheumatoid arthritis; osteoarthritis; inflammation; immunopathology; pathological features; joints; treatment; drug screening; traditional medicine

(This special issue belongs to the Section Medical Biology)

Young Researchers in Neuroscience

edited by Yansheng Du

submission deadline 31 Aug 2026 | 4 articles | Viewed by 36058 | Submission Open

Keywords: neurobiology; cell biology; molecular mechanisms; neural development; synaptic function; ion channels; neurotransmitter systems; gene expression; neuronal signaling; cellular physiology

(This special issue belongs to the Section Neuroscience)

Bone Cell Biology

edited by Yohei Abe and

Giulia Lanzolla

submission deadline 31 Aug 2026 | 7 articles | Viewed by 18522 | Submission Open

Keywords: osteoclast; osteoblast; osteocyte; bone density; macrophage; RANK; transcription factor; cell signaling

(This special issue belongs to the Section Cell Biology)

Biology, Ecology and Management of Harmful Algae

edited by Paul V. Zimba and

Jabulani R. Gumbo

submission deadline 31 Aug 2026 | 7 articles | Viewed by 9578 | Submission Open

Keywords: harmful algae; toxic algae; harmful algal bloom (HAB); excessive algae growth; microalgae and macroalgae; cyanobacteria; dinoflagellates; toxins; water quality; phytoplankton; water resources

Editorial Board Members’ Collection Series: Pathology of Cancer and Cardiovascular Disease

edited by

Mridula Chopra

Helen L. Fillmore

and

Maurizio Forte

submission deadline 31 Aug 2026 | 2 articles | Viewed by 8846 | Submission Open

Keywords: cancer; cardiovascular disease; biomarkers; gut microbiome; inflammation; health policy; diet and lifestyle

Lipid Metabolism in Plant Growth and Development

edited by Xiaohong Yu and Yingqi Cai

submission deadline 31 Aug 2026 | 2 articles | Viewed by 4366 | Submission Open

Keywords: lipid metabolism; lipid engineering; plant growth; plant development; lipid biosynthesis; lipid signaling; lipid transport; membrane structure; energy storage; plant– microbe interactions; stress response; nutrition value; cellular process

(This special issue belongs to the Section Plant Science)

Cellular and Molecular Biology of Liver Diseases

edited by Matthew McMillin

submission deadline 31 Aug 2026 | 1 articles | Viewed by 1646 | Submission Open

Keywords: drug-induced liver injury; cholestasis; hepatitis; metabolic dysfunction-associated steatotic liver disease; alcohol-associated liver disease

(This special issue belongs to the Section Cell Biology)

Host–Microbiome–Environment Interactions in Domestic and Wild Animals

edited by

Cesar A. Rosales-Nieto

and Cesar A. Meza-Herrera

submission deadline 31 Aug 2026 | 1 articles | Viewed by 1410 | Submission Open

Keywords: animal microbiome; environmental microbiota; host– microbiota interactions; wildlife microbiology; livestock health and productivity; microbiome and conservation; One Health approach; gut microbiota dynamics; microbial ecology; microbiome and reproduction; habitat– host microbiome linkages; multi-omics integration

(This special issue belongs to the Section Microbiology)

Regenerative Biology: Regeneration After Spinal Cord and Peripheral Nerve Injury

edited by

Alexandre Leite Rodrigues de Oliveira

submission deadline 31 Aug 2026 | 1 articles | Viewed by 1332 | Submission Open

Keywords: neuronal regeneration; peripheral nerve repair; spinal cord injury; axonal growth; neuroplasticity; glial cells; molecular signaling pathways; stem cells in nerve regeneration; neuroinflammation; animal models of nerve injury

(This special issue belongs to the Section Neuroscience)

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