The Role of Amyloid in Neurological Disorders

Dear Colleagues,

Interest in extracellular deposits of amorphous protein in the central and peripheral neurological system is growing due to new therapeutic strategies that could improve patients’ survival and quality of life. Amyloid-beta continues to be a most important diagnostic and prognostic issue for Alzheimer's disease (AD) and other neurological disorders. Neuropathy is a common manifestation of both hereditary and acquired forms of systemic amyloidosis and may present with progressive sensorimotor polyneuropathy, focal neuropathy, autonomic neuropathy, and other unusual clinical presentations.

Many aspects have been defined in several papers published; that said, there are many others aspects still to be understood. In particular, we do not yet know how the process of this degenerative disease starts, nor do we understand its mechanisms of progression.

This Special Issue aims to collate expertise on neurological disorders due to amyloid protein; in doing so, it will clarify the role of amyloid in the central and peripheral nervous system and its relationship with the immune system. Novel developments in terms of therapeutic options involving proteins, peptides, and antibodies will also be described.

Dr. Marny Fedrigo
Dr. Tamara Berno
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.