Purinergic Signalling in Bone
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Biological Factors".
Deadline for manuscript submissions: closed (31 May 2021) | Viewed by 2752
Special Issue Editors
Interests: osteoclast cell biology; cellular and molecular mechanisms underlying multinucleation; cellular and nuclear polyploidy; polyploidization; macrophage cell biology; bone homeostasis; bone pathology
Special Issues, Collections and Topics in MDPI journals
Interests: bone biology; bone disease; osteoclasts/osteoblasts and therapeutic drug design
Special Issue Information
Dear Colleagues,
Bone is a highly dynamic and specialized connective tissue. It is composed of inorganic mineral salts deposited within an organic collagen matrix, and three main types of bone cells: osteoclasts, osteoblasts and osteocytes. Bone homeostasis is maintained by the balanced functions of bone cells, while functional imbalance results in abnormal bone homeostasis and disease development. Bone homeostasis is largely influenced by substances present in the microenvironment. Extracellular purines and purinergic signalling are one of the most primitive forms of intercellular signalling. Purinergic signalling defines a group of receptors and intermembrane channels activated by extracellular purines such as ATP, ADP and AMP. Bone cells express multiple purinergic receptors. Metabolisms or tissue injuries can change the concentration of extracellular purines, influencing bone cell functions through purinergic receptors. It is now recognized that purinergic signalling is a modulator of many physiological and pathological conditions in bone, such as osteoporosis, rheumatoid arthritis and cancers.
This Special Issue aims to cover a selection of recent research topics and current review articles related to purinergic signalling in bone. Up-to-date review articles, commentaries and experimental papers are all welcome.
Dr. Noriko Takegahara
Dr. Hyunsoo Kim
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Purinergic receptors
- Purines
- Extracellular nucleotides
- ATP, ADP, AMP and adenosine
- Osteoblast
- Osteoclast
- Osteocyte
- Bone
- Metabolism
- Osteoporosis
- Osteopetrosis
- Rheumatoid arthritis
- Cancer
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
