Molecular Mechanisms and Novel Treatments of Stroke
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 15 February 2025 | Viewed by 53
Special Issue Editors
Interests: neurovascular dysfunction; stroke; VCID; TBI; Traumatic Optic Neuropathy (TON); diabetes; neurodegenerative disorders
Special Issues, Collections and Topics in MDPI journals
Interests: cancer biology; genetics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Ischemic stroke, primarily caused by a sudden interruption of cerebral blood flow, remains one of the leading causes of death and disability worldwide. This condition triggers a cascade of severe neural injuries and represents a major global health challenge, underscoring the urgent need for a deeper understanding of its molecular mechanisms and the development of novel therapeutic strategies. In recent years, significant efforts have been made to unravel the complex pathophysiology of ischemic stroke, focusing on key processes such as cellular excitotoxicity, oxidative stress, various forms of cell death, and neuroinflammation. These processes are regulated by a host of signaling pathways that are either detrimental or neuroprotective, forming a complex network that influences stroke outcomes.
The current Special Issue aims to provide a comprehensive overview of the molecular mechanisms involved in ischemic stroke and to explore novel therapeutic approaches targeting these pathways. It encompasses an in-depth analysis of the intricate signaling networks that govern the pathophysiological processes of stroke, with a particular focus on potential therapeutic targets and the latest advancements in clinical trials. Additionally, the issue discusses the role of advanced imaging techniques in assessing stroke progression and guiding treatment decisions, thereby highlighting the integration of molecular insights with clinical applications. By addressing these multifaceted aspects, this Special Issue seeks to advance our understanding of ischemic stroke and pave the way for innovative treatments that improve patient outcomes and reduce the global burden of this debilitating disease.
Dr. Saif Ahmad
Dr. Naseem Akhter
Guest Editors
Manuscript Submission Information
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Keywords
- ischemic stroke
- molecular mechanisms
- neuroinflammation
- signaling pathways
- therapeutic approaches
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