Special Issues

Biomolecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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The Immune System and Allergies
edited by
submission deadline 30 Nov 2024 | Viewed by 78 | Submission Open
Keywords: immune system; allergy; inflammation; hypersensitivity; immunology
(This special issue belongs to the Section Cellular Biochemistry)
Covalent and Non-covalent Functions of Ubiquitin and Ubiquitin-Like Molecules: Emerging Concepts
edited by Elena Santonico and Dmitris Xirodimas
submission deadline 30 Nov 2024 | Viewed by 69 | Submission Open
Keywords: ubiquitin; ubiquitin-like (UBL); post-translational modification (PTM); protein degradation; E1; E2; E3
Protein Interplay in Neurodegeneration, 2nd Edition
edited by
submission deadline 30 Nov 2024 | Viewed by 60 | Submission Open
Keywords: amyloidogenic proteins; metal ions; ROS; protein misfolding; neurons
(This special issue belongs to the Section Biomacromolecules: Proteins)
Obesity, Adipose Tissue and Cardiovascular Diseases (Second Edition)
edited by
submission deadline 30 Nov 2024 | Viewed by 56 | Submission Open
Keywords: obesity; cardiovascular diseases (CVDs); hypertension; dyslipidemia; atherosclerosis; adipose tissue; adipokines; cytokines
Biomolecules and Biomaterials for Tissue Engineering, 2nd Edition
edited by
submission deadline 10 Dec 2024 | Viewed by 76 | Submission Open
Keywords: tissue engineering; bioactive molecules; cellular function; proliferation
Recent Advances in Histone Deacetylase Research in Health and Disease
edited by and
submission deadline 15 Dec 2024 | 3 articles | Viewed by 4434 | Submission Open
Keywords: histone deacetylase; HDAC inhibitor; deacetylation; enzymatic and non-enzymatic activity; epigenetics; human disease
(This special issue belongs to the Section Enzymology)
Regulation of Notch Signaling Pathway and Its Relation to Diseases
edited by
submission deadline 15 Dec 2024 | 2 articles | Viewed by 3446 | Submission Open
(This special issue belongs to the Section Molecular Medicine)
Bioactive Molecules in the Control of Oxidative Stress and Oxidative Stress-Related Diseases
edited by
submission deadline 15 Dec 2024 | 1 articles | Viewed by 1145 | Submission Open
Keywords: antioxidants; bioactive molecules; ROS; redox signaling; oxidative stress-related diseases
Human Gut Microbiome and Diet in Health and Diseases: 2nd Edition
edited by
submission deadline 15 Dec 2024 | 1 articles | Viewed by 518 | Submission Open
Keywords: gut microbiome; microbiota; nutrition; functional foods; mucosal immunity; dysbiosis
Omics Technologies in Precision Medicine: Bridging Disease Research to Clinical Applications
edited by Xiao Chang
submission deadline 15 Dec 2024 | Viewed by 219 | Submission Open
Keywords: genome sequencing; single-cell sequencing; transcriptomics; proteomics; polygenic diseases
Embryo Implantation: New Molecular Insights in Endometrial Receptivity, Trophoblast Invasion and Signaling
edited by , Evdokia Dimitriadis and Lois A. Salamonsen
submission deadline 15 Dec 2024 | Viewed by 202 | Submission Open
Keywords: embryo implantation; endometrial receptivity; trophoblast invasion; signaling
Drosophila as a Model System to Study Metabolism
edited by
submission deadline 15 Dec 2024 | Viewed by 196 | Submission Open
Keywords: carbohydrate; lipid; amino acid; Drosophila; metabolism; insulin; TOR; autophagy; fasting
Recent Advances in RNA Editing and Modification submission deadline 15 Dec 2024 | Viewed by 99 | Submission Open
Keywords: RNA editing; RNA modification; deamination; transamination; pseudouridylation
Molecular Basis and Novel Treatment of Epilepsy
edited by
submission deadline 15 Dec 2024 | Viewed by 84 | Submission Open
Keywords: epilepsy; genetic basis; epileptogenesis; antiseizure drugs; novel treatment; translational research
New Insights into Essential Genes and Functions submission deadline 20 Dec 2024 | 2 articles | Viewed by 3904 | Submission Open
Keywords: gene regulation; omics data; essentiality; epigenetics; machine learning
(This special issue belongs to the Section Molecular Genetics)
Tissue Calcification in Normal and Pathological Environments
edited by
submission deadline 20 Dec 2024 | 2 articles | Viewed by 3547 | Submission Open
Keywords: calcification; ectopic mineralization; bone; heterotopic ossification; calcium phosphate; calcium carbonate; calcium oxalate; procalcific cell death
(This special issue belongs to the Section Molecular Medicine)
Advances in Cellular Biophysics: Transport and Mechanics
edited by Boris Musset and
submission deadline 20 Dec 2024 | Viewed by 287 | Submission Open
Keywords: membrane transport; ion transport; cellular biophysics; applied science; basic science
(This special issue belongs to the Section Molecular Biophysics)
State of the Art of Myology in 2024 submission deadline 20 Dec 2024 | Viewed by 247 | Submission Open
Keywords: embryonic myogenesis; adult myogenesis; exercise-induced muscle injury; muscular dystrophies and muscle diseases; sarcopenia; cachexia; rhabdomyosarcoma; muscle biophysics
(This special issue belongs to the Section Molecular Biology)
Breast Cancer: Molecular Mechanisms and Targeted Therapies
edited by
submission deadline 20 Dec 2024 | Viewed by 219 | Submission Open
Keywords: breast cancer; breast cancer metastasis; cancer metabolism; molecular and cellular basis of breast cancer; chemoresistance in breast cancer; triple-negative breast cancer and breast cancer stem cell
(This special issue belongs to the Section Molecular Medicine)
Cytoskeleton Structure and Dynamics in Health and Disease
edited by Alla S. Kostyukova and
submission deadline 20 Dec 2024 | Viewed by 135 | Submission Open
Keywords: actin; myosin; cytoskeleton; membrane-cytoskeleton associations; mechanotransduction; cytokinesis; nuclear cytoskeleton; contractile systems; cell motility; cell morphogenesis; cell adhesions; signal transduction; cytoskeleton structure and dynamics; microtubules; actin filaments; intermediate filaments organization
(This special issue belongs to the Section Biomacromolecules: Proteins)
Novel Insights of Endocrinology and Obesity
edited by Orien L. Tulp
submission deadline 20 Dec 2024 | Viewed by 79 | Submission Open
Keywords: obesity; overweight; metabolic syndrome (MetS); NIDDM; public health
Structural Biology of Protein
edited by Nabanita Saikia
submission deadline 30 Dec 2024 | Viewed by 73 | Submission Open
Keywords: structural characterization; protein structure– function paradigm; biophysical techniques; computational methods; conformational dynamics; drug discovery; protein– protein interactions
(This special issue belongs to the Section Biomacromolecules: Proteins)
Biochemistry in Medicine—Honorary Special Issue Commemorating Research and Work of Professors Jan O. Aaseth and Jan Alexander
edited by Sonia Distante and
submission deadline 31 Dec 2024 | 5 articles | Viewed by 18363 | Submission Open
Keywords: medical biochemistry; endocrinology; neurotoxic metals
(This special issue belongs to the Section Molecular Medicine)
Immune-Related Biomarkers: 2nd Edition submission deadline 31 Dec 2024 | 10 articles | Viewed by 15120 | Submission Open
Keywords: immune biomarker; proteomics; O-link; molecular medicine; prediction of disease; diagnosis/stratification of diseases; targeted immune therapy
(This special issue belongs to the Section Molecular Biomarkers)
Sowing the Seed to Ensure the Future of Plant Proteomics: Commemorative Issue in Honor of Dr. Dominique Job (1947–2022) submission deadline 31 Dec 2024 | 6 articles | Viewed by 9135 | Submission Open
Keywords: model and non-model plant species; crops; forestry; horticulture; ecology; flowering; floral induction; biennial bearing; fruit load; seed physiology; seed metabolism; seed germination; seed vigor; seed viability; seed longevity; desiccation tolerance; dormancy; post-genomics and omics; transcriptomics; proteomics; secretomics; systems biology; biotic stress; plant-microbe interactions (bacteria; fungi; viruses); abiotic stress; oxidative stress and reactive oxygen species (ROS); sulfur metabolism (biotin; Cys; Met; S-AdoMet; protein biotinylation); drought tolerance; post-translational modifications (PTMs); protein turnover; big data; data integration; data mining
(This special issue belongs to the Section Molecular Biology)
Early Adversity and the Immune Hypothesis: Call for a Dialogue between Basic and Clinical Neuroscience
edited by Arie Kaffman, Kate Ryan Kuhlman, Bridget L. Callaghan and Christine Heim
submission deadline 31 Dec 2024 | 5 articles | Viewed by 7107 | Submission Open
Keywords: early adversity; microglia; neuroinflammation; microbiome; psychopathology
(This special issue belongs to the Section Molecular Biology)
Advances in Protein-Ligand Interactions: From Structure, Function to Applications
edited by
submission deadline 31 Dec 2024 | 5 articles | Viewed by 7056 | Submission Open
Keywords: bioinformatics; compound libraries; computational biology; de novo drug design; drug discovery; ligand binding; machine learning; molecular docking; molecular dynamics; protein complexes
(This special issue belongs to the Section Molecular Structure and Dynamics)
Cell Biology and Biomedical Application of Galectins submission deadline 31 Dec 2024 | 3 articles | Viewed by 6774 | Submission Open
Keywords: galectins; cell differentiation; stem cells; apoptosis; autophagy; cell adhesion; glycobiology; post-translational modifications; transmembrane signaling; protein trafficking; cancer; heart diseases; fibrosis; inflammation; targeted therapeutics; galectin inhibitors
(This special issue belongs to the Section Chemical Biology)
Biomolecule Contributors to Long COVID Syndrome submission deadline 31 Dec 2024 | 2 articles | Viewed by 6671 | Submission Open
Keywords: long COVID-19; post-COVID-19; post-viral; SARS-CoV-2; chronic fatigue syndrome; multiorgan disease
(This special issue belongs to the Section Molecular Medicine)
State of the Art in Antiviral Therapy and Viral Diseases Diagnosis: An Update to 2022-2023 submission deadline 31 Dec 2024 | 2 articles | Viewed by 4948 | Submission Open
(This special issue belongs to the Section Molecular Medicine)
Feature Papers in the Natural and Bio-Derived Molecules Section submission deadline 31 Dec 2024 | 4 articles | Viewed by 4940 | Submission Open
(This special issue belongs to the Section Natural and Bio-derived Molecules)
Molecular Mechanisms Underlying Liver Diseases
edited by
submission deadline 31 Dec 2024 | 4 articles | Viewed by 4264 | Submission Open
Keywords: pathogenesis of liver diseases; molecular mechanisms; organelle damages; genetic determinants; organ– organ interactions; biomarkers; in vivo models of liver diseases; therapeutic insights
(This special issue belongs to the Section Cellular Biochemistry)
Genetic and Genomic Biomarkers of Cancer
edited by
submission deadline 31 Dec 2024 | 3 articles | Viewed by 4099 | Submission Open
Keywords: laboratory genetics and genomics; genetic and genomic biomarkers; diagnostic; prognostic; predictive; companion diagnosis; targeted therapy
(This special issue belongs to the Section Molecular Biomarkers)
Biomolecules and Their Impact on Biology and Translational Applications: Celebrating the Pioneering Work of Prof. Ho Jeong Kwon
edited by and Hye Jin Kang
submission deadline 31 Dec 2024 | 4 articles | Viewed by 3554 | Submission Open
Keywords: biomolecules; cancer; angiogenesis; autophagy; GPCRs; translational applications; target identification; proximity-labeling; molecular docking; molecular probe; molecular pharmacology
(This special issue belongs to the Section Cellular Biochemistry)
Neuroimmune Interactions in Neuropsychiatric Diseases
edited by
submission deadline 31 Dec 2024 | 1 articles | Viewed by 2609 | Submission Open
Keywords: neurology; psychiatry; immunity; glia
(This special issue belongs to the Section Molecular Biology)
Mitochondrial ROS in Health and Disease
edited by
submission deadline 31 Dec 2024 | 3 articles | Viewed by 2520 | Submission Open
Keywords: aging; apoptosis; respiratory chain; redox signaling; paclitaxel
(This special issue belongs to the Section Chemical Biology)
Recent Insights into Metal Binding Proteins
edited by Pedro Tavares and Alice S. Pereira
submission deadline 31 Dec 2024 | 2 articles | Viewed by 2404 | Submission Open
Keywords: metal-binding proteins; metalloproteins; metalloenzymes; metal homeostasis
(This special issue belongs to the Section Biomacromolecules: Proteins)
Advances in Galectins
edited by Anu Paul and Diyoly Ayona
submission deadline 31 Dec 2024 | 2 articles | Viewed by 2304 | Submission Open
Keywords: galectins; carbohydrate-binding proteins; galectin– microbe
(This special issue belongs to the Section Biomacromolecules: Proteins)
Advances in Liver X Receptors
edited by Kaori Endo-Umeda and
submission deadline 31 Dec 2024 | 1 articles | Viewed by 2017 | Submission Open
Keywords: liver X receptor; lipid metabolism; cholesterol; oxysterol; atherosclerosis; non-alcoholic steatohepatitis; inflammation; tumor immunity
(This special issue belongs to the Section Molecular Biology)
The Role of Arginine and Arginine Metabolites in Cerebro- and Cardiovascular Disease Targeted Therapy
edited by Edzard Schwedhelm, , Roman N. Rodionov and Ying Wang
submission deadline 31 Dec 2024 | 1 articles | Viewed by 1747 | Submission Open
Keywords: alanine:glyoxylate aminotransferase 2; asymmetric dimethylarginine; cyclic guanosine monophosphate; dimethylarginine dimythylaminohydrolase 1; homoarginine; nitric oxide; symmetric dimethylarginine
(This special issue belongs to the Section Molecular Medicine)
Molecular Mechanisms in DNA and RNA Damage and Repair submission deadline 31 Dec 2024 | 2 articles | Viewed by 1687 | Submission Open
Keywords: reactive oxygen species; DNA damage; DNA repair; RNA damage; RNA repair; molecular mechanisms; biomarkers; antioxidant and redox strategies; oxidative stress
(This special issue belongs to the Section Molecular Biomarkers)
New Insights into Cardiometabolic Diseases submission deadline 31 Dec 2024 | 2 articles | Viewed by 1575 | Submission Open
Keywords: metabolic diseases; hypertension; obesity; type-2 diabetes; vascular diseases; acute vascular events
(This special issue belongs to the Section Molecular Medicine)
Mitochondrial Medicine: A Themed Issue in Honor of Prof. Dr. Carl A. Pinkert
edited by
submission deadline 31 Dec 2024 | 1 articles | Viewed by 1450 | Submission Open
Keywords: mitochondrial biology; mitochondrial disease; mitochondrial DNA; mitochondrial medicine; metabolism; therapeutics; oxidative phosphorylation; reactive oxygen species
(This special issue belongs to the Section Molecular Medicine)
Homocysteine and H2S in Health and Disease submission deadline 31 Dec 2024 | 1 articles | Viewed by 1403 | Submission Open
Keywords: homocysteine (Hcy); hydrogen sulfide (H2S); oxidative stress; inflammation
(This special issue belongs to the Section Chemical Biology)
Role of Probiotics in Health and Disease submission deadline 31 Dec 2024 | 1 articles | Viewed by 1178 | Submission Open
Keywords: human well-being; digestive health; immune system response; prevention; treatment
(This special issue belongs to the Section Molecular Medicine)
Molecular and Cellular Mechanisms of Ischemic Stroke
edited by
submission deadline 31 Dec 2024 | 1 articles | Viewed by 1147 | Submission Open
Keywords: ischemic stroke; neuroprotection; brain circulation; rehabilitation medicine
Harnessing Protein Design and Engineering for Therapeutic Applications
edited by Julia Shifman and Norman Metanis
submission deadline 31 Dec 2024 | 1 articles | Viewed by 1092 | Submission Open
Keywords: therapeutic peptides and proteins; protein design and engineering; chemical protein synthesis; chemoselective protein modification; posttranslational protein modification
(This special issue belongs to the Section Molecular Structure and Dynamics)
Advances in p53 Research 2024 submission deadline 31 Dec 2024 | 1 articles | Viewed by 1045 | Submission Open
Keywords: p53; small molecules; tumor suppressor; apoptosis; tumor– host interaction; targeted therapies; tumor microenvironment (TME)
Signal Transduction to Transcription Factors in Health and Disease—Honorary Special Issue Commemorating the Work of Prof. Athanasios G. Papavassiliou submission deadline 31 Dec 2024 | 1 articles | Viewed by 973 | Submission Open
(This special issue belongs to the Section Molecular Medicine)
Mechanisms of Formation of Biomolecule Complexes: Theory, Experiment, Applications submission deadline 31 Dec 2024 | 1 articles | Viewed by 895 | Submission Open
Keywords: biomolecule complexes; biomolecule coacervates; complex stability; mechanisms of formation of biomolecule complexes; phase separation; application of biomolecule complexes in biomedical industry
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