Submit to Biomolecules Review for Biomolecules Propose a Special Issue

Journal Menu

Journal Browser

Special Issues

Biomolecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

Section

Search by Title/Keyword

Order results

Display

Results per page

LDL Receptor Family in Metabolic Homeostasis, Neurodevelopmental Disorders, and Signaling Pathways

edited by

María-Paz Marzolo

submission deadline 31 Oct 2026 | Viewed by 303 | Submission Open

Keywords: LDL receptor family; lipid metabolism; cholesterol homeostasis; neurodevelopmental and neuropsychiatric disorders; neurodegeneration; receptor-mediated endocytosis; Wnt and reelin signaling pathways; apolipoproteins; Alzheimer's disease; Parkinson's disease

Feature Papers in Section "Biological Factors", 2nd Edition

edited by

Tracey A. Martin

submission deadline 31 Oct 2026 | Viewed by 274 | Submission Open

Keywords: neurotransmitters; cytokines; chemokines; hormones; connexins; androgen; estrogens; coagulation factors; hypoxia-inducible factors; transcription factors; signaling; receptors; interferon

(This special issue belongs to the Section Biological Factors)

Synthetic Biology's Potential to Address Undruggable Targets and Difficult-to-Treat Diseases

edited by

Dario Mizrachi

submission deadline 31 Oct 2026 | Viewed by 252 | Submission Open

Keywords: synthetic biology; protein engineering; drug development; biologics; undruggable targets

(This special issue belongs to the Section Molecular Medicine)

SAM Domains in Health and Diseases: Structural and Functional Insights

edited by

Flavia Anna Mercurio

and

Marilisa Leone

submission deadline 31 Oct 2026 | Viewed by 250 | Submission Open

Keywords: SAM domains; oligomer- and polymer-forming SAM; mid-loop/end-helix architecture of binding; SAM physiological and pathological signaling pathways; SAM domains as drug targets

(This special issue belongs to the Section Molecular Biophysics: Structure, Dynamics, and Function)

Modern Studies of Nucleic Acid Dynamics

edited by

Gary A. Meints

submission deadline 31 Oct 2026 | Viewed by 236 | Submission Open

Keywords: nucleic acid dynamics; DNA; RNA; nucleic acid energetics; dynamics of biomolecular recognition; timescales and magnitudes of dynamics

Fibronectin, Integrins and Related Molecules in Health and Diseases

edited by

Yoshikazu Takada

submission deadline 31 Oct 2026 | Viewed by 232 | Submission Open

Keywords: integrin; fibronectin; cytokines

(This special issue belongs to the Section Chemical Biology)

Calcium Signaling: Molecular Mechanisms and Therapeutic Targets in Cardiovascular Diseases

edited by Jianjie Ma and

Yuchen Chen

submission deadline 31 Oct 2026 | Viewed by 218 | Submission Open

Keywords: calcium signaling; excitation– contraction coupling; cardiovascular disease; ryanodine receptor and ion channelopathies; gene therapy and precision medicine

(This special issue belongs to the Section Chemical Biology)

Pathophysiological Insights into Congenital Myasthenic Syndromes

edited by Xin-Ming Shen, Kinji Ohno and Duygu Selcen

submission deadline 31 Oct 2026 | Viewed by 214 | Submission Open

Keywords: neuromuscular junction; neurotransmission; developmental biology; myasthenia; congenital myasthenic syndrome; human genetics; variant; mutation; animal model

(This special issue belongs to the Section Molecular Medicine)

Application of Spectral Analysis in Disease Diagnosis and Treatment

edited by

Entesar Al-Hetlani

and

Igor Lednev

submission deadline 31 Oct 2026 | Viewed by 204 | Submission Open

Keywords: molecular spectroscopy; mass spectrometry; medical diagnostics; disease treatment/treatment monitoring; lipidomics/proteomics/metabolomics; biofluids; machine learning

(This special issue belongs to the Section Molecular Medicine)

Molecular Advances in Multiple Sclerosis

edited by

Felix Javier Jiménez Jiménez

submission deadline 31 Oct 2026 | Viewed by 170 | Submission Open

Keywords: multiple sclerosis; molecular pathogenesis; neuroinflammation; demyelination; neurodegeneration; genetic susceptibility; GWAS; therapeutic strategies

(This special issue belongs to the Section Molecular Biology)

Supramolecular Peptide Materials for Biomedical Applications

edited by

Anna Mitraki

and

Dhwanit R. Dave

submission deadline 31 Oct 2026 | Viewed by 168 | Submission Open

Keywords: supramolecular peptides; peptide self-assembly; peptide-based biomaterials; biomedical applications; drug delivery; tissue engineering

(This special issue belongs to the Section Bio-Engineered Materials)

Advancing Health, Industrial, and Husbandry Sciences Through Bioinformatics and Biomaterials

edited by Xian-Ze Meng and

Dongqing Wei

submission deadline 31 Oct 2026 | Viewed by 147 | Submission Open

Keywords: molecular evolution; epidemiology; computational virology; genomics; material protection

(This special issue belongs to the Section Bioinformatics and Systems Biology)

Genetic and Epigenetic Mechanisms in Craniofacial Development and Disease

edited by

Zhaoming Wu

and

Timothy C. Cox

submission deadline 31 Oct 2026 | Viewed by 135 | Submission Open

(This special issue belongs to the Section Molecular Genetics)

Recent Advances in the Enzymatic Synthesis of Bioactive Compounds—2nd Edition

edited by

Bartłomiej Zieniuk

submission deadline 31 Oct 2026 | Viewed by 135 | Submission Open

Keywords: biocatalysis; biotransformation; enzyme-catalyzed reactions; whole-cell catalysis; green chemistry; enzymes; phenolic compounds; polyphenols; lipases; lipophilization; enzymatic synthesis; esterification; transesterification; green and sustainable chemistry approaches; lipid modification

(This special issue belongs to the Section Enzymology)

Cancer and Chronic Disease: Molecular Mechanisms and Translational Oncology in Multimorbidity

edited by Kiven Erique Lukong,

and

submission deadline 31 Oct 2026 | Viewed by 135 | Submission Open

Keywords: cancer; chronic diseases; multimorbidity; molecular mechanisms; epigenetics; chronic inflammation; molecular aberrations; translational oncology

(This special issue belongs to the Section Molecular Medicine)

Properties and Functions of Endometrial Stromal Cells—2nd Edition

edited by

Toshihiro Sakurai

and

Mikihiro Yoshie

submission deadline 31 Oct 2026 | Viewed by 117 | Submission Open

Keywords: endometrium; endometriosis; molecular reproduction; implantation; decidualization; placentation; inflammation; reproductive endocrinology; assisted reproductive technology; molecular reproductive biology

(This special issue belongs to the Section Molecular Reproduction)

Molecular and Cellular Mechanisms of Aortic Diseases: From Biomarkers to Therapeutic Strategies

edited by Maria Giovanna Scioli

submission deadline 31 Oct 2026 | Viewed by 115 | Submission Open

Keywords: aortic diseases; vascular remodeling; extracellular matrix degradation; vascular smooth muscle cells; endothelial dysfunction; inflammation and cytokines; signal transduction pathways; molecular biomarkers; prognostic markers; targeted therapies; precision medicine; translational research; pharmacological interventions

(This special issue belongs to the Section Molecular Biomarkers)

Novel Insights into Endocannabinoidome and Cannabis

edited by

Emmanuel Onaivi

submission deadline 31 Oct 2026 | Viewed by 113 | Submission Open

Keywords: cannabinoids; endocannabinoids; cannabis; marijuana; inflammation; neuroimmune crosstalk; alcohol; opioids; addiction; mental disorders; gut– brain axis

(This special issue belongs to the Section Natural and Bio-derived Molecules)

High-Field MRI-Guided Boron Neutron Capture Therapy (BNCT): Targeted Delivery and Efficacy Monitoring in Glioma

edited by

Silvia Capuani

and Paola Porcari

submission deadline 31 Oct 2026 | Viewed by 110 | Submission Open

Keywords: boron neutron capture therapy (BNCT); accelerator-based neutron sources; glioma MRI; 19F MRI and MRS; boronophenylalanine (BPA); fluorinated boron agents; glioblastoma; quantitative treatment monitoring; precision radiotherapy; tanslational neuro-oncology

(This special issue belongs to the Section Chemical Biology)

DMSO as a Biomolecule to Treat Various Health Conditions

edited by

Frank Krause

submission deadline 31 Oct 2026 | Viewed by 95 | Submission Open

Keywords: pain killer; stroke; spinal cord injuries; autoimmune diseases; cancer

(This special issue belongs to the Section Chemical Biology)

Microtubule-Based Motor Proteins in Health and Disease: Mechanisms, Regulation and Cellular Functions

edited by Weihong Qiu

submission deadline 31 Oct 2026 | Viewed by 90 | Submission Open

Keywords: motor proteins; kinesins; dyneins; microtubule

(This special issue belongs to the Section Biomacromolecules: Proteins, Nucleic Acids and Carbohydrates)

Molecular Pathogenesis and Genetic Adaptation of Bacterial Pathogens

edited by

David Roy

submission deadline 31 Oct 2026 | Viewed by 89 | Submission Open

Keywords: host– pathogen interactions; virulence; proteins; enzymes; toxins; nucleic acids; metabolites; antibiotic resistance; biomolecules

(This special issue belongs to the Section Molecular Biology)

Advances in Porphyria and Liver Disease Research

edited by Andrew G. Smith

submission deadline 31 Oct 2026 | Viewed by 39 | Submission Open

Keywords: porphyria; liver disease; heme; mechanisms; susceptibilities

(This special issue belongs to the Section Molecular Medicine)

Advances in the Molecular Mechanisms of Inflammatory Arthritis and Inflammation-Related Bone Changes: 2nd Edition

edited by

Carlo Perricone

submission deadline 1 Nov 2026 | 1 articles | Viewed by 957 | Submission Open

Keywords: inflammatory arthritis; molecular mechanisms; bone changes; osteoimmunology; autoimmunity

(This special issue belongs to the Section Molecular Medicine)

Synthetic Chemistry in Drug Discovery: Novel Compounds for Antimicrobial and Antioxidant Applications

edited by

Hawraz Ibrahim M. Amin

submission deadline 7 Nov 2026 | 3 articles | Viewed by 5081 | Submission Open

Keywords: synthetic chemistry; drug discovery; essential oils; antimicrobial activity; antiproliferative agents; antioxidant properties; bioactive molecules; structure– activity relationship; natural product derivatives; medicinal chemistry; chemical synthesis; pharmacological evaluation

(This special issue belongs to the Section Chemical Biology)

Research Progress on Anti-Aging with Natural Products

edited by

Sang-Han Lee

submission deadline 10 Nov 2026 | 2 articles | Viewed by 5461 | Submission Open

Keywords: natural products; anti-aging signaling; autophagy; antioxidants; skin aging; bioactive compounds; molecular mechanisms; translational applications

(This special issue belongs to the Section Biological Factors)

The Mechanisms of Nervous System Injury

edited by

Krisztián Pajer

and Antal Nógrádi

submission deadline 10 Nov 2026 | Viewed by 46 | Submission Open

Keywords: nervous system injury; neuroprotection; stem cell secretome; inflammasome; extracellular vesicles; neuroinflammation; regenerative medicine; molecular mechanisms

(This special issue belongs to the Section Molecular Biology)

The Kynurenine Pathway in Mood Disorders: From Mechanisms to Therapeutics

edited by Gregory F. Oxenkrug

submission deadline 17 Nov 2026 | 1 articles | Viewed by 836 | Submission Open

Keywords: kynurenine; tryptophan; mood disorders; stress; inflammation

(This special issue belongs to the Section Biological Factors)

Advances in S-Triazine-Based Therapeutics: From Antimicrobials to Neurodegenerative Disease Modulators

edited by

Danuta Drozdowska

submission deadline 20 Nov 2026 | 1 articles | Viewed by 1904 | Submission Open

Keywords: 1; 3; 5-triazine; s-triazine; biological activity; drug discovery; antibacterial agent; antifungal agent; anticancer activity; antiviral agents; antimalarial activity; anti-Alzheimer’ s activity; anti-Alzheimer’ s agents; cholinesterase inhibitors; BACE1 inhibitors; anti-neurodegenerative effects; anti-inflammatory activity; molecular mechanisms of s-triazine activity

(This special issue belongs to the Section Chemical Biology)

Translational Insights from Insect Immunity: Antimicrobial Strategies and Infection Models

edited by

Sylwia Stączek

and

Agnieszka Zdybicka-Barabas

submission deadline 20 Nov 2026 | Viewed by 77 | Submission Open

Keywords: insect immunity; antimicrobial peptides; host-pathogen interaction; innate immune response; infection models

(This special issue belongs to the Section Molecular Medicine)

Molecular Signaling Pathways in Tumorigenesis and Tumor Suppression, 2nd Edition

edited by

Kiyoshi Ohtani

submission deadline 20 Nov 2026 | Viewed by 63 | Submission Open

Keywords: cancer cell biology; RB; E2F; ARF; p53

(This special issue belongs to the Section Molecular Biology)

Tumor Biomarkers and Precision Therapy: Epigenetic, Immune, and Proteomic Strategies

edited by

Ximena Maria Muresan

and

Ioana Ecaterina Pralea

submission deadline 25 Nov 2026 | 1 articles | Viewed by 1143 | Submission Open

Keywords: tumors; biomarkers; epigenetics; immune targets; proteomics; mass-spectrometry based proteomics; targeted therapy

(This special issue belongs to the Section Molecular Biomarkers)

Molecular and Cellular Mechanisms of Therapy Resistance in Acute Myeloid Leukemia

edited by

Yong-Mi Kim

submission deadline 25 Nov 2026 | Viewed by 220 | Submission Open

Keywords: acute myeloid leukemia; molecular mechanism; cellular mechanism; therapy resistance; microenvironment; immunotherapy

(This special issue belongs to the Section Cellular Biochemistry)

Metabolic Pathways, COVID-19 and Other Viral Acute Respiratory Infections: Mechanisms and Clinical Implications: 2nd Edition

edited by

Simona Iftimie

and

Jordi Camps

submission deadline 30 Nov 2026 | 3 articles | Viewed by 10462 | Submission Open

Keywords: COVID-19; respiratory syncytial virus; influenza; SARS-CoV-2; viral acute respiratory infections; metabolic pathways; herpes virus

(This special issue belongs to the Section Molecular Medicine)

Advances and Novel Strategies for Studying Post-Translational Modifications (PTMs)

edited by

Yue Chen

submission deadline 30 Nov 2026 | 3 articles | Viewed by 9423 | Submission Open

Keywords: post-translational modifications proteomics; chemical biology; cell signaling; epigenetics; metabolic regulation; cancer; diabetes; microbiome; aging

(This special issue belongs to the Section Molecular Biology)

Impact of Systemic Inflammation on Neuroinflammation, Neurodegenerative Diseases and Mental Disorders

edited by

Raymond Chuen-Chung Chang

submission deadline 30 Nov 2026 | 1 articles | Viewed by 3516 | Submission Open

Keywords: systemic inflammation; neuroinflammation diseases; neurodegenerative diseases; mental disorders

(This special issue belongs to the Section Molecular Medicine)

Molecular Mechanisms and Signaling Pathways in Autoimmune Diseases

edited by

Daniele Saverino

submission deadline 30 Nov 2026 | 2 articles | Viewed by 3387 | Submission Open

Keywords: autoimmune diseases; molecular mechanisms; signaling pathways; therapeutic targets; biomarkers

(This special issue belongs to the Section Molecular Biology)

Novel Insights and Applications of Pluripotent Stem Cells

edited by

Huseyin Sumer

and Ben Rollo

submission deadline 30 Nov 2026 | 2 articles | Viewed by 2345 | Submission Open

Keywords: pluripotent stem cells; pluripotency; differentiation; stem cell transplant; regenerative medicine; disease modeling; organoids; therapeutic screening; cell therapies; drug discovery

(This special issue belongs to the Section Cellular Biochemistry)

Glycomics in Health, Aging and Disease

edited by

Domenico Garozzo

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1060 | Submission Open

Keywords: glycome; glycobiology; glycochemistry; glycans; glycoconjugates

(This special issue belongs to the Section Cellular Biochemistry)

Key Mechanisms in the Pathogenesis of ALS

edited by

Natalia N. Ninkina

and

Michail S. Kukharsky

submission deadline 30 Nov 2026 | Viewed by 402 | Submission Open

Keywords: amyotrophic lateral sclerosis; motor neuron disease; neurodegeneration; pathogenesis; protein aggregation; non-coding RNA; biomarkers

(This special issue belongs to the Section Molecular Biomarkers)

Molecular Chaperones in Neurodegenerative Diseases: Mechanistic Role and Therapeutic Potential

edited by Umesh Kumar Jinwal

submission deadline 30 Nov 2026 | Viewed by 322 | Submission Open

Keywords: molecular chaperones; neurodegenerative diseases; Hsp90; Hsp70; Alzheimer's Disease; Parkinson’ s Disease; Huntington's disease; amyotrophic lateral sclerosis

(This special issue belongs to the Section Molecular Biophysics: Structure, Dynamics, and Function)

Citrin Deficiency: Molecular Pathogenesis and Novel Targets for Therapy

edited by

Takeyori Saheki

submission deadline 30 Nov 2026 | Viewed by 219 | Submission Open

Keywords: citrin deficiency; pathogenesis; therapeutic procedures

(This special issue belongs to the Section Molecular Medicine)

Structural and Functional Insights into Metalloantibiotics

edited by

Li-June Ming

submission deadline 30 Nov 2026 | Viewed by 199 | Submission Open

Keywords: metal ion; biomolecules; enzyme; antimicrobial resistance

(This special issue belongs to the Section Enzymology)

Advances in Molecular Mechanisms and Predictive Biomarkers in Cancer Immunotherapy

edited by Fabrizio Nelli,

Carlo Signorelli

and

Gloria Pessina

submission deadline 30 Nov 2026 | Viewed by 198 | Submission Open

Keywords: immune checkpoint inhibitors; solid tumors; predictive biomarkers; resistance mechanisms; PD-1/PD-L1 pathway; efficacy; response; immune-related adverse events; real-world evidence

(This special issue belongs to the Section Molecular Biomarkers)

Molecular and Genetic Basis of Hormonal Signaling and Inter-Organ Crosstalk in Steatotic Liver Disease

edited by Karuna Rasineni and Sundararajan Mahalingam

submission deadline 30 Nov 2026 | Viewed by 171 | Submission Open

Keywords: metabolic liver disease; organ crosstalk; hormones; gut– liver axis; adipose– liver axis; neuroendocrine control of liver function

(This special issue belongs to the Section Molecular Medicine)

Gut Microbiome and Related Diseases in Animals

edited by

Alessandro Gramenzi

submission deadline 30 Nov 2026 | Viewed by 169 | Submission Open

Keywords: intestinal microbiota; dysbiosis; prebiotic; probiotic; postbiotic; nutraceutical; companion animals

(This special issue belongs to the Section Biological Factors)