Special Issues

Biomolecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Matrix Metalloproteinases: Mechanisms, Functions and Therapeutic Potential
edited by , Joshua W. Ogony and
submission deadline 31 May 2025 | Viewed by 48 | Submission Open
Keywords: matrix metalloproteinases; endopeptidases; MMP inhibitor; tissue homeostasis; disease progression
Ion Channels in Cardiovascular and Metabolic Diseases
edited by
submission deadline 31 May 2025 | Viewed by 36 | Submission Open
Keywords: Na+ channel; Ca2+ channel; K+ channel; TRP channel; store-operated channel; Cl− channel; cation channel; ryanodine receptor; mechanosenstive channels; piezo channels; SGLT-1 transporters; membrane transporters
(This special issue belongs to the Section Biological Factors)
The Role of Mechanotransduction in Cellular Biology submission deadline 31 May 2025 | Viewed by 9 | Submission Open
Keywords: cell membrane; cytosol; nuclear membrane; integrin; mechanotransduction; map kinase pathway; ERKs; JNKs; p38/SAPKs; YAP/TAZ; Hippo pathway
(This special issue belongs to the Section Cellular Biochemistry)
iPSC-Derived Model for Mitochondrial Diseases
edited by Kristina Xiao Liang
submission deadline 31 May 2025 | Submission Open
Keywords: iPSC; mitochondrial disease; cellular remodeling; mitochondrial dysfunction; therapeutic screening
(This special issue belongs to the Section Molecular Biology)
Tissue-Specific Organelle Dynamics submission deadline 1 Jun 2025 | Viewed by 39 | Submission Open
Keywords: organelles crosstalk; organelles contact sites; organelle dynamics
(This special issue belongs to the Section Cellular Biochemistry)
Molecular Advances in Rett Syndrome and Other Chromatin Related Disorders
edited by and Salvatore Fioriniello
submission deadline 15 Jun 2025 | 1 articles | Viewed by 730 | Submission Open
Keywords: Rett syndrome and other chromatin disorders; epigenetic diseases; molecular alterations in Rett syndrome and other chromatin diseases; novel genes associated with chromatin disorders; MeCP2-mediated molecular mechanisms; roles of epigenetic modulators in chromatin-related diseases; preclinical studies for chromatin diseases; novel diagnostic; prognostic and therapeutic approaches for chromatin disorders
(This special issue belongs to the Section Molecular Medicine)
Biomarkers and Molecular Basis of Psychiatry
edited by
submission deadline 25 Jun 2025 | Viewed by 83 | Submission Open
Keywords: mental health; bipolar disorders; mood; anxiety; psychosis; schizophrenia; biomarkers
(This special issue belongs to the Section Biological Factors)
The Illumination of Biophysical Mechanisms by Hydrogen Exchange: A Themed Issue in Honor of Professor S. Walter Englander
edited by
submission deadline 30 Jun 2025 | 1 articles | Viewed by 2546 | Submission Open
Keywords: hydrogen exchange chemistry; HX– NMR; HX-MS; protein folding; allostery; protein binding; protein thermodynamics; protein biophysics; protein function
(This special issue belongs to the Section Molecular Biology)
Chemical Biology and Biotechnology of Nucleosides, Nucleotides, and Nucleic Acids
edited by and
submission deadline 30 Jun 2025 | 1 articles | Viewed by 1397 | Submission Open
Keywords: nucleosides; nucleotides; nanostructure; circular ssDNA; circular RNA; quadruplex; conjugate; lncRNA; DNAzyme; ribozyme
Advances in Biomolecular Research: Selected Papers from the 2024 Biomedical Sciences Symposium
edited by and Jun-Tao Guo
submission deadline 30 Jun 2025 | Viewed by 120 | Submission Open
Keywords: cancer biology; regenerative medicine; infectious disease; artificial intelligence in health research; nanomaterials; drug design
Mechanosensitivity and Ion Channels
edited by Olivia García-Suarez and Yolanda García-Mesa
submission deadline 30 Jun 2025 | Viewed by 102 | Submission Open
Keywords: mechanosensation; piezo ion channels; mechanosensitivity ion channels; mechanotrasduction
(This special issue belongs to the Section Molecular Biophysics)
Molecular Interactions between Obesity and Breast Cancer
edited by Fokhrul Hossain
submission deadline 30 Jun 2025 | Viewed by 87 | Submission Open
Keywords: breast cancer; breast cancer subtypes; triple-negative breast cancer; obesity; molecular mechanisms; molecular interactions
(This special issue belongs to the Section Molecular Medicine)
Advances in Computational Approaches for the Discovery of Therapeutics and Personalized Medicine submission deadline 30 Jun 2025 | Viewed by 69 | Submission Open
Keywords: high-throughput virtual screening; CADD; machine learning; biologics design; off-target effect prediction
(This special issue belongs to the Section Bioinformatics and Systems Biology)
Metabolic Pathways, COVID-19 and Other Viral Acute Respiratory Infections: Mechanisms and Clinical Implications: 2nd Edition
edited by and
submission deadline 30 Jun 2025 | Viewed by 60 | Submission Open
Keywords: COVID-19; respiratory syncytial virus; influenza; SARS-CoV-2; viral acute respiratory infections; metabolic pathways; herpes virus
Molecular Advances in Drug Resistance and Novel Therapies for Cancer submission deadline 30 Jun 2025 | Viewed by 47 | Submission Open
Keywords: cell signalling; cancer treatment; cancer metastasis; target validation; cancer and new molecules; cancer and cellular organelles
(This special issue belongs to the Section Biological Factors)
Studies of Protein Dynamics Using Fluorescence Correlation Spectroscopy (FCS)
edited by Jieqiong Lou
submission deadline 30 Jun 2025 | Viewed by 23 | Submission Open
Keywords: protein dynamics; Fluorescence Correlation Spectroscopy (FCS); protein interactions; subcellular environments
Cellular Signaling in Cancer
edited by , Shabana Bano and Kasturi Nayak
submission deadline 30 Jun 2025 | Viewed by 20 | Submission Open
Keywords: signaling pathways; cancer; anti-cancer
(This special issue belongs to the Section Cellular Biochemistry)
Genomics in Biodiversity Conservation (Vertebrates and Invertebrates) submission deadline 31 Aug 2025 | Viewed by 81 | Submission Open
Keywords: genomics; mitochondrial genome; genetic diversity; phylogenetic analyses; conservation genetics; gene arrangements; evolution
(This special issue belongs to the Section Molecular Genetics)
Roles of Alpha-1 Antitrypsin in Human Health and Disease Models
edited by
submission deadline 15 Sep 2025 | Viewed by 181 | Submission Open
Keywords: alpha-1 antitrypsin; serine proteinase inhibitor (SERPIN); autoimmunity; inflammation; aging; cancer
(This special issue belongs to the Section Molecular Medicine)
Identifying New Therapeutic Targets for Psychiatric Disease Using Transcriptomics and Epigenomics submission deadline 30 Sep 2025 | Viewed by 41 | Submission Open
Keywords: epigenomics; psychiatric disease; psychiatry; therapeutic target; transcriptomics
(This special issue belongs to the Section Molecular Genetics)
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