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Biosensors
Special Issues
Acoustic Wave Biosensors
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Acoustic Wave Biosensors

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensor and Bioelectronic Devices".

Deadline for manuscript submissions: closed (15 March 2024) | Viewed by 4899

Special Issue Editors

Prof. Dr. Yong J. Yuan

E-Mail Website
Guest Editor
Laboratory of Biosensing and MicroMechatronics, Southwest Jiaotong University, Chengdu 610031, China
Interests: biochips; synthetic biology; molecular dynamics; point-of-care testing
Prof. Dr. Xiaoxiao He

E-Mail Website
Guest Editor
State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Biology, Hunan University, Changsha 410082, China
Interests: aptasensor; bionanomedicine
Dr. Lili Xiong

E-Mail Website
Guest Editor
Department of Bioengineering, Southwest Jiaotong University, Chengdu 610031, China
Interests: developmental biology; microbial synthetic biology; tumor molecular biology

Special Issue Information

Dear Colleagues,

The purpose of this Special Issue is to provide an overview on the research and development status of dependable, efficient, and portable and miniaturized biosensors such as the quartz crystal microbalance (QCM) and surface acoustic wave (SAW) for biosensing and medical diagnosis developed during the last decade, especially practical point-of care devices. Acoustic wave-based biosensors have broad development prospects and many application opportunities. A range of biosensing applications are therefore expected among the immunochemical analysis, in situ virus or bacteria determination, microfluidic automation, cell manipulation, personalized medicine and drug discovery, etc. Manuscripts focused on theoretical models and mechanisms are also welcome for submission to this Special Issue. The challenges and future development of point-of care testing biosensors will likely be focused on the improvement and achievement of high-throughput screening, multi-frequency, simultaneous analysis and multi-analyte detection, and integration capabilities.

Prof. Dr. Yong J. Yuan
Prof. Dr. Xiaoxiao He
Dr. Lili Xiong
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • bulk acoustic wave
  • surface acoustic wave
  • microfabrication
  • microorganism (bacteria, viruses)
  • biomarkers (proteins, DNA, RNA)
  • surface modification
  • molecular interaction
  • molecular simulation
  • signal processing
  • POCT

Published Papers (2 papers)

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Research

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18 pages, 6184 KiB  
Article
Surface Acoustic Wave (SAW) Sensors for Hip Implant: A Numerical and Computational Feasibility Investigation Using Finite Element Methods
by Muhammad Hafizh, Md Mohiuddin Soliman, Yazan Qiblawey, Muhammad E. H. Chowdhury, Mohammad Tariqul Islam, Farayi Musharavati, Sakib Mahmud, Amith Khandakar, Mohammad Nabil and Erfan Zal Nezhad
Biosensors 2023, 13(1), 79; https://doi.org/10.3390/bios13010079 - 2 Jan 2023
Cited by 2 | Viewed by 2596
Abstract
In this paper, a surface acoustic wave (SAW) sensor for hip implant geometry was proposed for the application of total hip replacement. A two-port SAW device was numerically investigated for implementation with an operating frequency of 872 MHz that can be used in [...] Read more.
In this paper, a surface acoustic wave (SAW) sensor for hip implant geometry was proposed for the application of total hip replacement. A two-port SAW device was numerically investigated for implementation with an operating frequency of 872 MHz that can be used in more common radio frequency interrogator units. A finite element analysis of the device was developed for a lithium niobate (LiNBO3) substrate with a Rayleigh velocity of 3488 m/s on COMSOL Multiphysics. The Multiphysics loading and frequency results highlighted a good uniformity with numerical results. Afterwards, a hip implant geometry was developed. The SAW sensor was mounted at two locations on the implant corresponding to two regions along the shaft of the femur bone. Three discrete conditions were studied for the feasibility of the implant with upper- and lower-body loading. The loading simulations highlighted that the stresses experienced do not exceed the yield strengths. The voltage output results indicated that the SAW sensor can be implanted in the hip implant for hip implant-loosening detection applications. Full article
(This article belongs to the Special Issue Acoustic Wave Biosensors)
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Review

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13 pages, 1652 KiB  
Review
Application of Shear Horizontal Surface Acoustic Wave (SH-SAW) Immunosensor in Point-of-Care Diagnosis
by Chia-Hsuan Cheng, Hiromi Yatsuda, Mikihiro Goto, Jun Kondoh, Szu-Heng Liu and Robert Y. L. Wang
Biosensors 2023, 13(6), 605; https://doi.org/10.3390/bios13060605 - 1 Jun 2023
Cited by 1 | Viewed by 2162
Abstract
Point-of-care testing (POCT), also known as on-site or near-patient testing, has been exploding in the last 20 years. A favorable POCT device requires minimal sample handling (e.g., finger-prick samples, but plasma for analysis), minimal sample volume (e.g., one drop of blood), and very [...] Read more.
Point-of-care testing (POCT), also known as on-site or near-patient testing, has been exploding in the last 20 years. A favorable POCT device requires minimal sample handling (e.g., finger-prick samples, but plasma for analysis), minimal sample volume (e.g., one drop of blood), and very fast results. Shear horizontal surface acoustic wave (SH-SAW) biosensors have attracted a lot of attention as one of the effective solutions to complete whole blood measurements in less than 3 min, while providing a low-cost and small-sized device. This review provides an overview of the SH-SAW biosensor system that has been successfully commercialized for medical use. Three unique features of the system are a disposable test cartridge with an SH-SAW sensor chip, a mass-produced bio-coating, and a palm-sized reader. This paper first discusses the characteristics and performance of the SH-SAW sensor system. Subsequently, the method of cross-linking biomaterials and the analysis of SH-SAW real-time signals are investigated, and the detection range and detection limit are presented. Full article
(This article belongs to the Special Issue Acoustic Wave Biosensors)
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