Exploring Negative Symptoms of Schizophrenia: Where Do We Stand?
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Psychiatric Diseases".
Deadline for manuscript submissions: 25 November 2024 | Viewed by 676
Special Issue Editors
Interests: schizophrenia; negative symptoms; physical activity; antipsychotics; brain imaging; neurostimulation
Interests: first episode psychosis; negative symptoms; treatment response; treatment resistance; suicidal behaviors; illness trajectories; prediction
Interests: psychosis; negative symptoms; understanding reduced motivation in psychotic disorders; clinical trials, user involvement; global mental health
Special Issue Information
Dear Colleagues,
Negative symptoms are prevalent among many individuals diagnosed with schizophrenia, and these significantly impact their social functioning and overall quality of life. Despite their significant impact, negative symptoms have often been overshadowed in diagnostic criteria, treatment approaches, and research pertaining to schizophrenia, especially when compared to positive symptoms. Additionally, there remains a lack of clarity in clinical practice regarding the definition and differentiation between primary and secondary negative symptoms. Nevertheless, recognizing secondary negative symptoms is crucial, as this can enable tailored treatment interventions, especially considering the fact that these symptoms can stem from various factors such as positive symptoms, substance abuse, medication side effects, or depressive episodes.
The objective of this Special Issue, therefore, is to offer fresh insights into negative symptoms by presenting clinical tools, brain imaging studies, physiological data, and innovative treatment modalities.
Controlled trials involving medications targeting neurotransmitter systems other than dopamine, or exploring adjunctive therapies alongside antipsychotics, such as neurostimulation, cognitive remediation, physical activity, or social rehabilitation, are anticipated. Furthermore, research aimed at enhancing our understanding of the pathophysiology underlying negative symptoms is encouraged, and original research, meta-analyses, and reviews may be accepted.
Prof. Dr. Sonia Dollfus
Prof. Dr. Ingrid Melle
Dr. Ann Faerden
Guest Editors
Manuscript Submission Information
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Keywords
- schizophrenia
- negative symptoms
- brain imaging
- pathophysiology
- scales
- cognitive remediation
- physical activity
- neurostimulation
- social rehabilitation
- neurotransmitter
- drugs
- quality of life
- treatment
- antipsychotics
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