Metabolism of Cancer Cells
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Tumor Microenvironment".
Deadline for manuscript submissions: closed (21 September 2023) | Viewed by 254
Special Issue Editors
Interests: Wnt signaling; differential Kat3 coactivator usage; stem cells and cancer stem cells; aging; chemical genomics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
A deeper understanding of the biology of therapy resistance is important for the development of optimal strategies to attain complete cures for cancer. Cancer stem cells (CSC) are the major cause of therapy resistance, being associated with metastasis and constituting the cause of disease relapse. Normal somatic stem cells (SSC) and CSC share many common features, thereby complicating the safe elimination of CSC. Both SSC and CSC have the capacity to self-renew and differentiate, exist in different states (i.e., quiescent versus activated), and are plastic (i.e., can cycle between the different states). A Smorgasbord is defined as a mixture of many different hot and cold dishes that are arranged so that one can serve oneself as much as is desired in a buffet style. It is now clear that both normal stem cells and CSC can sample many different “dishes” at the Smorgasbord table to suit their “behaviors” and “lifestyles” by matching their metabolic needs. Limiting the ability of CSC to pick and choose their food from the “Smorgasbord table” may thereby provide a mechanism for preventing therapy resistance. This Special Issue will focus on the “dietary habits” of cancer cells and CSC in an effort to determine how we may be able to therapeutically exploit this knowledge.
Prof. Dr. Michael Kahn
Dr. Xiaohui Hu
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
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Keywords
- cancer cells
- metabolism
- cancer stem cells
- quiescence
- therapy resistance
- glycolysis
- fatty acid oxidation
- OXPHOS
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