Screening and Early Detection of HPV-Related Cancers
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Causes, Screening and Diagnosis".
Deadline for manuscript submissions: closed (1 February 2024) | Viewed by 2841
Special Issue Editors
Interests: oropharyngeal cancer; anal cancer; liquid biopsy; genomics; molecular diagnostics
Special Issue Information
Dear Colleagues,
Early detection of cancer increases the chances of successful treatment and is associated with the use of rapid screening tests and their availability to patients. In cancers of HPV etiology, the stages of transformation of the virus state in the cell and its evolution from the infectious to the neoplastic state seem to be of great importance in the diagnosis. The choice of the HPV genome target in early diagnosis or screening cannot be arbitrary but is adapted to the moment of transformation, whether it is to be used to detect chronic infection or cancer. We are particularly interested in original articles that report the identification of novel proteins or cellular pathways whose early modification by the presence of the viral genome leads to tumor progression. We welcome review papers that attempt to identify new trends enable the early detection of neoplastic lesions and their use in future prognostic strategies of HPV-related cancers. In the era of collected information, we are also interested in progress in constructing algorithms for artificial intelligence.The thematic scope of this Special Issue includes:
- the influence of molecular and clinical factors modifying the prognostic value of HPV,
- aspects of distinguishing a chronic infection from a transient infection,
- epigenetic and transcriptomic signature of immune tolerance,
- benefits and limitations of ctHPV-based liquid biopsy for early detection,
- the importance of HPV testing in cytological tests,
- the impact of the vaccine on diagnostics of HPV-dependent cancers,
- HPV application for building an artificial intelligence algorithm for the early detection of HPV-related cancer.
Dr. Agnieszka M. Mazurek
Prof. Dr. Guojun Li
Guest Editors
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Keywords
- liquid biopsy
- cytology
- microsurgery
- colonoscopy
- colposcopy
- laryngoscopy
- artificial intelligence
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