Cancer Induced Organ Dysfunctions (Cachexia)
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Molecular Cancer Biology".
Deadline for manuscript submissions: 31 July 2025 | Viewed by 37
Special Issue Editor
Interests: cancer-induced cachexia; ovarian cancer; cancer stem cells; targeting of cancer and cancer stem cells; signaling pathways in tumorigenesis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cancer cachexia is a multifactorial syndrome and is associated with the loss of body weight and organ dysfunctions in cancer patients. It varies from 42% to 80%, depending on the oncological status, and is directly responsible for approximately 30% of deaths in cancer patients. It is a multi-organ and complex syndrome with a largely unknown etiology. Metabolic disorders and inflammation are the hallmarks of cancer cachexia. Several mechanisms and signaling pathways have been reported leading to the development of cachexia; however, a definitive orchestrating mechanism remains elusive. Furthermore, no FDA-approved therapeutic regimen for cancer-induced cachexia (dysfunction) is currently available.
This Special Issue is focused on understanding the mechanisms of cancer-induced organ dysfunctions (cachexia) and the therapeutic approach in the field of cachexia, including basic, preclinical and clinical studies, and the application of current technologies for the diagnosis of cachexia.
Prof. Dr. Sham S. Kakar
Guest Editor
Manuscript Submission Information
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Keywords
- cancer
- cachexia
- organ dysfunction
- cancer-induced cachexia
- cancer-induced organ dysfunction
- muscle wasting
