Advancements in Child, Adolescent, and Young Adult Cancer Survivorship

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Pediatric Oncology".

Deadline for manuscript submissions: 20 April 2025 | Viewed by 829

Special Issue Editor


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Guest Editor
Paediatric Environmental Health Specialty Unit, Department of Pediatrics, Clinical University Hospital Virgen of Arrixaca, University of Murcia, 30120 Murcia, Spain
Interests: cancer prevention; health-related quality of life; lifestyle; cancer survivors; chronic diseases

Special Issue Information

Dear Colleagues,

We are pleased to announce a Special Issue entitled "Advancements in Child, Adolescent, and Young Adult Cancer Survivorship" to be published in Cancers. As Guest Editor, I am excited to invite you to contribute your valuable research to this significant endeavor.

Childhood cancer survivorship presents unique challenges and opportunities, ranging from long-term health effect surveillance to psychosocial factors influencing quality of life. This Special Issue aims to showcase experiences, models, and approaches in survivorship programs, late effect monitoring, chronic diseases in long-term follow-up, health-related quality of life, resiliency, lifestyles, psychosocial factors, educational and rehabilitation strategies, as well as barriers and disparities in accessing quality care amongst cancer survivors.

We welcome original research articles, reviews, and perspectives that contribute to our understanding of survivorship in pediatric oncology. Submissions should align with the scope outlined above and can cover a wide range of topics within the realm of child, adolescent, and young adult cancer survivorship.

Dr. Juan A. Ortega-García
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • late effects
  • chronic diseases
  • prevention
  • rehabilitation
  • remediation
  • psychosocial factors
  • quality of life
  • lifestyles
  • surveillance
  • survivors
  • educational strategies

Published Papers (1 paper)

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Research

13 pages, 2080 KiB  
Article
Telomere Length in Adolescent and Young Adult Survivors of Childhood Cancer
by Meerim Park, Dong-Eun Lee, Yuna Hong, Jin Kyung Suh, Jun Ah Lee, Myungshin Kim and Hyeon Jin Park
Cancers 2024, 16(13), 2344; https://doi.org/10.3390/cancers16132344 - 26 Jun 2024
Viewed by 677
Abstract
We examined the leukocyte relative telomere length (RTL) in Korean adolescent and young adult (AYA) survivors of childhood cancer and evaluated the association of leukocyte RTL with multiple factors, including malignancy type, cancer treatment, age, and chronic health conditions (CHCs). Eighty-eight AYA survivors [...] Read more.
We examined the leukocyte relative telomere length (RTL) in Korean adolescent and young adult (AYA) survivors of childhood cancer and evaluated the association of leukocyte RTL with multiple factors, including malignancy type, cancer treatment, age, and chronic health conditions (CHCs). Eighty-eight AYA survivors of childhood cancer with a median follow-up period of 73 months were recruited. RTL in pediatric cancer survivors was not significantly shorter than the predicted value for age-matched references. Neither age at diagnosis nor duration of therapy influenced the RTL. Among the 43 patients with hematologic malignancies, those who underwent allogeneic hematopoietic stem cell transplantation (HSCT) showed a significant shortening of the RTL compared with those who did not (p = 0.039). Among the 15 patients who underwent allogeneic HSCT, those who developed acute graft-versus-host disease (GVHD) of grade II or higher had significantly shorter RTL than those who did not (p = 0.012). Patients with grade II CHCs had significantly shorter RTL than those without CHCs or with grade I CHCs (p = 0.001). Survivors with ≥2 CHCs also exhibited shorter RTL (p = 0.027). Overall, pediatric cancer survivors had similar telomere lengths compared to age-matched references. HSCT recipients and patients with severe or multiple CHCs had shorter telomeres. GVHD augmented telomere attrition in HSCT recipients. Full article
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