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Cancers
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Novel Advances in Surgery for Prostate Cancer
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Novel Advances in Surgery for Prostate Cancer

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Clinical Research of Cancer".

Deadline for manuscript submissions: 30 November 2024 | Viewed by 828

Special Issue Editor

Dr. Vincenzo De Marco

E-Mail Website
Guest Editor
Azienda Ospedaliera Universitaria Integrata—Borgo Trento Hospital, Verona, Italy
Interests: prostate cancer; radical prostatectomy; robot-assisted surgery; robotic surgery

Special Issue Information

Dear Colleagues,

We are excited to present the Special Issue entitled "Novel Advances in Surgery for Prostate Cancer", featuring cutting-edge insights into the surgical management of prostate cancer. This collection highlights innovative technologies and techniques aimed at refining diagnosis, treatment, and patient outcomes. Leading experts contribute diverse articles exploring state-of-the-art image-guided technologies, robot-assisted technologies, adoption of novel robotic platforms, and other minimally invasive approaches. Addressing a global health challenge, these advancements underscore the importance of precision and patient-centric strategies. We extend our gratitude to contributors for enriching this Special Issue, anticipating its role as a valuable resource for clinicians, surgeons, and researchers, fostering continued progress in prostate cancer surgery.

Dr. Vincenzo De Marco
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • prostate cancer
  • radical prostatectomy
  • robot-assisted surgery
  • robotic platform
  • technology
  • single port
  • alternative approaches
  • focal therapy

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Published Papers (1 paper)

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Research

35 pages, 1541 KiB  
Article
Real-Life Comparative Analysis of Robotic-Assisted Versus Laparoscopic Radical Prostatectomy in a Single Centre Experience
by Stefano Salciccia, Valerio Santarelli, Giovanni Battista Di Pierro, Francesco Del Giudice, Giulio Bevilacqua, Giovanni Di Lascio, Alessandro Gentilucci, Roberta Corvino, Valentina Brunelli, Greta Basile, Carlo Maria Scornajenghi, Lorenzo Santodirocco, Luca Gobbi, Davide Rosati, Martina Moriconi, Valeria Panebianco, Fabio Massimo Magliocca, Daniele Santini, Mattia Alberto Di Civita, Flavio Forte, Marco Frisenda, Giorgio Franco and Alessandro Sciarraadd Show full author list remove Hide full author list
Cancers 2024, 16(21), 3604; https://doi.org/10.3390/cancers16213604 - 25 Oct 2024
Viewed by 506
Abstract
Background: The advantage of a robotic-assisted (RARP) over a laparoscopic (LRP) approach in radical prostatectomy (RP) remains to be demonstrated. Aim: The aim of the study is to use a homogeneous population in real life and single primary surgeon surgery to [...] Read more.
Background: The advantage of a robotic-assisted (RARP) over a laparoscopic (LRP) approach in radical prostatectomy (RP) remains to be demonstrated. Aim: The aim of the study is to use a homogeneous population in real life and single primary surgeon surgery to analyze the oncological and functional results based on the type of surgical approach and pathological features. Methods: This is a prospective trial on non-metastatic prostate cancer (PCa) patients considered after a multidisciplinary decision to conduct a RP, using a RARP or LRP approach. A real-life setting was analyzed at our Urological Departments using homogeneous criteria for the management of PCa cases and a single surgeon experience on 444 cases (284 LRP and 160 RARP). Results: Mean operating time was significantly lower in RARP (153.21 ± 25.1 min) than in LRP (173.33 ± 44.3 min) (p < 0.001). In cases submitted to an extended lymph node dissection (eLND), the mean number of lymph nodes removed was 15.16 ± 7.83 and 19.83 ± 4.78, respectively, in LRP and RARP procedures (p < 0.001), but positive lymph nodes (pN1) were similarly found in 15.8% of LRP patients and 13.6% of RARP patients (p = 0.430). Surgical margins (SM) positivity was not significantly higher in the RARP group (20.0%) when compared to the LRP group (15.9%) (p = 0.145). During the postoperative follow-up, a biochemical recurrence (BCR) was detected in 14.4% and 7.5% of cases in the LRP and RARP group, respectively, (p = 0.014). Better results of PAD tests at 3-month intervals using the RARP approach (mean pad weight 75.57 ± 122 g and 14 ± 42 g, respectively, in LRP and RARP (p < 0.01)) were described. Conclusions: In the comparison between the RARP and LRP approach, a clear advantage of the robotic approach is a significant reduction in operating times, days of hospitalization, and postoperative catheterization compared to laparoscopic surgery. It is not possible to describe any certain oncological advantage both in terms of surgical margins and pathological lymph nodes removed. In RARP cases a reduction to the limit of significance is described in terms of biochemical recurrence. RARP produces a more rapid recovery of urinary continence at 3 months postoperatively without significant advantages in terms of erective potency recovery. Full article
(This article belongs to the Special Issue Novel Advances in Surgery for Prostate Cancer)
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