Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
8.0
4.5
Journals
Cancers
Special Issues
Hippo Signaling in Cancer
share announcement

Hippo Signaling in Cancer

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Tumor Microenvironment".

Deadline for manuscript submissions: closed (20 February 2024) | Viewed by 1589

Special Issue Editors

Dr. Ying Yan

E-Mail Website
Guest Editor
Department of Radiation Oncology, College of Medicine, University of Nebraska Medical Center, Omaha, NE, USA
Interests: Hippo; AKT1; phosphorylation; radiation; DSB
Prof. Dr. Michel Ouellette

E-Mail Website
Guest Editor
Department of Internal Medicine, College of Medicine, University of Nebraska Medical Center, Omaha, NE, USA
Interests: Hippo; pancreatic cancer; telomeres/telomerase; Rac1, GTPase, and K-ras signaling

Special Issue Information

Dear Colleagues,

This Special Issue in Cancers aims to present the current achievements of scientific investigations focusing on Hippo signaling, with emphasis on oncogenesis, cancer progression, metastasis, cancer therapy resistance, and the development of targeted anticancer agents based on Hippo signaling. The topic is of particular importance because the dysregulation of Hippo signaling occurs in many types of human cancer and contributes to cancer development, progression, metastasis, and therapeutic resistance. Recent advances in methods and technologies of cell biology, molecular biology, immunology, and biochemistry have enabled fast growth in this area. This Special Issue aims to present the most important recent achievements in this unique field of cancer research. 

Dr. Ying Yan
Prof. Dr. Michel Ouellette
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

 

Published Papers (1 paper)

Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

35 pages, 7506 KiB  
Article
The Interaction of Mechanics and the Hippo Pathway in Drosophila melanogaster
by Jia Gou, Tianhao Zhang and Hans G. Othmer
Cancers 2023, 15(19), 4840; https://doi.org/10.3390/cancers15194840 - 3 Oct 2023
Viewed by 1130
Abstract
Drosophila melanogaster has emerged as an ideal system for studying the networks that control tissue development and homeostasis and, given the similarity of the pathways involved, controlled and uncontrolled growth in mammalian systems. The signaling pathways used in patterning the Drosophila wing disc [...] Read more.
Drosophila melanogaster has emerged as an ideal system for studying the networks that control tissue development and homeostasis and, given the similarity of the pathways involved, controlled and uncontrolled growth in mammalian systems. The signaling pathways used in patterning the Drosophila wing disc are well known and result in the emergence of interaction of these pathways with the Hippo signaling pathway, which plays a central role in controlling cell proliferation and apoptosis. Mechanical effects are another major factor in the control of growth, but far less is known about how they exert their control. Herein, we develop a mathematical model that integrates the mechanical interactions between cells, which occur via adherens and tight junctions, with the intracellular actin network and the Hippo pathway so as to better understand cell-autonomous and non-autonomous control of growth in response to mechanical forces. Full article
(This article belongs to the Special Issue Hippo Signaling in Cancer)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-1
Back to TopTop