Re-Irradiation: New Challenges and Perspectives
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Methods and Technologies Development".
Deadline for manuscript submissions: closed (30 May 2024) | Viewed by 2192
Special Issue Editors
Interests: treatment planning; irradiation techniques; multimodality imaging; dose tolerance of tissues
Special Issue Information
Dear Colleagues,
In the last years, due to the prolonged survival, the number of patients that experience a recurrence or a new second cancer has been rapidly increasing. Emerging evidence from meta-analysis shows that re-irradiation is a first line option for failure after radiotherapy. Technological advances, together with new treatment modalities and fractionations, allow to manage challenging scenarios where the evaluation of therapeutic gain has to take into account the need of treating the tumor while impinging on tissues that have already been irradiated. Many aspects need to be considered; from the more clinical ones, like a true understanding of the radiobiology behind re-irradiation, to the most technical, like image registration, re-planning and dose accumulation.
This Special Issue aims to give an overview of the current strategies applied, clinical, physical and technological, together with suggesting new perspectives for the future; like fully exploiting information from multimodality imaging in the characterization of pre irradiated tissues or using the combination of different radiotherapy modalities, protons or heavy ions, or focusing on the treatment planning and delivery aspects.
We are, therefore, pleased to invite you to give your contribution with original articles and reviews that are within the scope of the journal, sharing your experience in details, also highlighting the limitations of your studies, so that the published papers can really represent an enrichment for the colleagues that are called to face similar challenges.
We look forward to receiving your contributions.
Dr. Valeria Landoni
Dr. Giuseppe Sanguineti
Guest Editors
Manuscript Submission Information
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Keywords
- re-irradiation
- radiotherapy
- therapeutic gain
- tissues tolerance to radiation
- image registration
- treatment planning
- dose accumulation
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