Molecular Biology of Colorectal Cancers
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Molecular Cancer Biology".
Deadline for manuscript submissions: closed (30 October 2023) | Viewed by 26407
Special Issue Editors
Interests: gastrointestinal cancer; prognosis; prediction
Special Issues, Collections and Topics in MDPI journals
Interests: protein microarrays and mass-spectrometry-based proteomics; spatial proteomics; quantitative proteomics; integrated omics; systems biology; chronic diseases; colorectal cancer; Alzheimer’s disease; biomarkers
Special Issues, Collections and Topics in MDPI journals
Interests: gastric cancer; pancreatic cancer; colorectal cancer; metastatic melanoma
Special Issues, Collections and Topics in MDPI journals
2. Health Research Institute of the Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain
Interests: tumors; histopathology; immunohistochemistry; histology; cancer diagnostics; surgical pathology; prognostic markers; cancer biomarkers; cancer biology; tumor markers
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
As a pathologist for more than 30 years now, I have had the exciting chance to live in the front line the amazing advances in the comprehension of colorectal cancer (CRC). As known, CRC was one of the first tumors in which molecular mechanisms were investigated and confirmed. We now accept that tumors that look identical on microscopic grounds are different at the molecular level, and this explains the varying patient outcomes that we usually face in clinical practice. Tumors look alike but are not the same! However, and having said so, even in the era of molecular medicine and targeted therapies, most of the patients that develop metastatic CRC eventually die of disease with a poor quality of life and significant years of potential life lost , specially when ever younger people are getting affected by this disease. Much remains to be known about the mechanisms that contribute to the aggressive behaviour of CRC and factors predicting therapy response. This special issue is devoted to recent research involving molecular mechanisms underlying colorectal carcinoma, including epigenetic changes, interaction with the environment, and analysis by omics technologies. A fascinating world is open to research, and we would like to invite you to join us in this issue in which we hope to shed some more light into the biology of this common and still lethal tumor.
I am happy to share this journey with my colleagues. Today’s science can only progress through the collaboration between clinicians and basic scientists and I deeply thank my coeditors for their continuing efforts and help in the last decade.
I hope you enjoy this special issue.
Dr. María Jesús Fernández-Aceñero
Chief of the Molecular Pathology section at the Pathology Department
Hospital Clínico San Carlos, Madrid, Spain
Dr. María Jesús Fernández Aceñero
Dr. Rodrigo Barderas Manchado
Dr. Javier Martínez Useros
Dr. Cristina Díaz del Arco
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- colorectal carcinoma
- metastatic behaviour
- predictive factors
- prognostic factors
- signaling pathways
- tumor microenvironment
- epithelial-mesenchymal transition
- omics technologies
- targeted therapies
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