Lymph Node Dissection for Gynecologic Cancers
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Methods and Technologies Development".
Deadline for manuscript submissions: 30 October 2024 | Viewed by 2628
Special Issue Editor
Interests: ovarian cancer; oncology; surgery; gynecologic oncology; gynaecological surgery; hysterectomy; cancer prevention; laparoscopic surgery; gynecologic surgical procedures; pelvic reconstructive surgery
Special Issue Information
Dear Colleagues,
In this Special Issue, we will focus on the role of lymph node dissection (either sentinel lymph node or lymphadenectomy) for gynecological cancers.
In vulvar, endometrial, and cervical cancer, sentinel lymph node (SLN) mapping is becoming increasingly popular and is finding its application in everyday surgical practice. However, this is opening many new unanswered questions. The innovations in technique and the attempt to standardize it, the oncological meaning of isolated tumor cells and low-volume metastasis, the role of completion lymphadenectomy in positive sentinel lymph node cases, the possible use of sentinel node in fertility-sparing procedures, and, in general, the oncological safety of the SLN procedure are just some of the challenges we are facing in this new era.
Lymph node dissection has been recently tested in advanced-stage epithelial ovarian cancers. However, its role is still debated in early-stage epithelial and some non-epithelial ovarian cancers. The possible therapeutic benefit of lymphadenectomy is controversial, but it plays a role in staging, helping the clinician decide on adjuvant treatment. Recent studies suggest SLN as a possible procedure, but it is still experimental.
Additionally, the significant advances in imaging and molecular techniques are, in general, challenging this surgical procedure's role and helping in tailoring surgical and adjuvant treatment.
This Special Issue aims to give an up-to-date point of view on the role of lymph node dissection (either sentinel lymph node or lymphadenectomy) in treating all gynecological cancers in all settings (from fertility-sparing to radical surgery). We hope it will help in defying and stratifying the patients who will or will not benefit from this procedure. We also hope that it will give readers information about the impact of lymph node dissection on morbidities and patient-related outcomes, the choice of adjuvant treatments, and the diffusion of the different approaches in different healthcare systems.
Therefore, we are pleased to invite you to submit your original research or review articles for this Special Issue.
Research areas may include (but are not limited to) the following:
- Vulvar cancer; vaginal cancer; cervical cancer; endometrial cancer; epithelial ovarian cancer; non-epithelial ovarian cancer; rare gynecological cancers.
- Lymphadenectomy; sentinel lymph node; surgical technique.
- Low volume metastasis (Isolated tumor cells and/or micrometastasis); Positive nodes in general.
- Imaging, molecular, clinical data to define patients who will benefit or not from lymph node dissection.
- Role of lymph node dissection in the choice of adjuvant treatment.
- Role of lymph node dissection in fertility-sparing treatments.
- Role of lymph node dissection at the time of recurrence.
We look forward to receiving your contributions.
Dr. Fabio Landoni
Guest Editor
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