Targeting Autophagy for Cancer Treatment
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".
Deadline for manuscript submissions: closed (30 April 2022) | Viewed by 67763
Special Issue Editor
Interests: cancer; therapeutic targets; drug discovery; chemoresistance; autophagy; apoptosis; IAPs; lung cancer
Special Issue Information
Dear Colleagues,
Autophagy is a cellular catabolic process that facilitates nutrient recycling from damaged organelles and other cellular components through lysosomal degradation. Deregulation of this process is associated with several pathological processes, including cancer. Therefore, modulation of autophagy is emerging as a new therapeutic approach for the treatment of cancer. Nevertheless, autophagy in cancer may have cytoprotective or cytotoxic roles; thus, the identification of the role of autophagy in each tumor context is crucial.
In this issue, experts in the field will review the role of autophagy in cancer, as well as discuss current therapeutic strategies that modulate autophagy for the treatment of cancer. Moreover, this issue will include new research articles related to different aspects of targeting autophagy for the treatment of cancer, including works related to deciphering the role of autophagy in tumors, the identification of new therapeutic targets in autophagy, novel therapeutic approaches targeting autophagy or the use of autophagy modulators in combination therapies to overcome chemoresistance, among others.
Dr. Vanessa Soto-Cerrato
Guest Editor
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Keywords
- autophagy
- chemoresistance
- cancer treatment
- autophagy inhibitors
- tumor sensitization
- autophagy activators
- autophagic cell death
- autophagy biomarkers
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