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Cancers
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Exercise and Nutrition in Cancer Care
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Exercise and Nutrition in Cancer Care

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Survivorship and Quality of Life".

Deadline for manuscript submissions: closed (30 April 2022) | Viewed by 8229

Special Issue Editor

Prof. Dr. Freerk Baumann

E-Mail Website
Guest Editor
Department of Internal Medicine, University of Cologne, Center for Integrated Oncology (CIO) Aachen Bonn Cologne Dusseldorf, University Hospital of Cologne, Kerpener Str. 62, 50937 Cologne, Germany
Interests: Exercise; Nutrition; Oncology; Cancer; Side effects; Mechanism

Special Issue Information

Dear Colleagues,

Over the last few decades, cancer incidence and survival rates have both increased. At the same time, modern diagnostic and therapeutic methods have led to a steady improvement in oncological treatment outcomes. However, the occurrence of medical side effects depends to a large extent on the individual patient's physical and psychological condition, nutritional status, and intact organ functions. Therapy delays or dose reductions limit the therapeutic potential of treatment. Adverse therapeutic consequences such as polyneuropathy, cognitive impairment, susceptibility to infection, muscle weakness, malnutrition, and fatigue occur frequently and may significantly reduce the quality of life in the long term.

Evidence variably shows that targeted nutritional therapy and exercise therapy intervention can reduce side effects and support the recovery process. In the care of cancer patients, these two interventions have found a significant place. However, many questions remain, not only clinical questions but also mechanistic ones. This Special Issue aims to provide relevant evidence and address the following topics:

  • Effective early detection options (screening) of malnutrition and physical inactivity;
  • Biological mechanisms;
  • Exercise and nutrition with consideration of new therapeutic methods;
  • Influence of physical activity and nutrition interventions in different cancer entities on relevant clinical physical and psychological outcomes;
  • Implementation projects for oncology care.

Prof. Dr. Freerk Baumann
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Exercise
  • Nutrition
  • Oncology
  • Cancer
  • Side effects
  • Mechanism

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Further information on MDPI's Special Issue polices can be found here.

Published Papers (2 papers)

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Research

12 pages, 1266 KiB  
Article
Cost-Effectiveness of Nutrient Supplementation in Cancer Survivors
by Amy L. Shaver, Theresa A. Tufuor, Jing Nie, Shauna Ekimura, Keri Marshall, Susan Hazels Mitmesser and Katia Noyes
Cancers 2021, 13(24), 6276; https://doi.org/10.3390/cancers13246276 - 14 Dec 2021
Cited by 6 | Viewed by 4281
Abstract
Cancer patients are at risk for malnutrition; the aim of this study was to provide a cost-effectiveness analysis of dietary supplementation in cancer survivors. We estimated prevalence of supplementation, hospitalization rates, quality of life (QOL), cost of care and mortality among cancer survivors. [...] Read more.
Cancer patients are at risk for malnutrition; the aim of this study was to provide a cost-effectiveness analysis of dietary supplementation in cancer survivors. We estimated prevalence of supplementation, hospitalization rates, quality of life (QOL), cost of care and mortality among cancer survivors. We built a decision analytic model to simulate life-long costs of health care and supplementation and QOL among cancer survivors with and without supplementation. Cost of supplements was derived from national pharmacy databases including single- and multivitamin formularies. One-way and probabilistic sensitivity analysis were performed to evaluate the robustness of the incremental cost-effectiveness ratio (ICER) to changes in supplementation costs and duration. The study cohort represented the national cancer survivor population (average age 61 years, 85% white, 52% male, and 94% insured). Hospitalization rates for supplement users and non-users were 12% and 21%, respectively. The cost of hospitalization was $4030. Supplementation was associated with an additional 0.48 QALYs (10.26 vs. 9.78) at the incremental cost of $2094 ($236,933 vs. $234,839) over the remaining lifetime of survivors (on average 13 years). Adequate nutrition provides a cost-effective strategy to achieving potentially optimum health. Further studies are needed to determine the effects of specific nutrient doses and supplementation on long-term outcomes per cancer type. Full article
(This article belongs to the Special Issue Exercise and Nutrition in Cancer Care)
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12 pages, 964 KiB  
Article
Maintaining Weight Loss in Obese Men with Prostate Cancer Following a Supervised Exercise and Nutrition Program—A Pilot Study
by Rebekah L. Wilson, Dennis R. Taaffe, Robert U. Newton, Nicolas H. Hart, Philippa Lyons-Wall and Daniel A. Galvão
Cancers 2021, 13(14), 3411; https://doi.org/10.3390/cancers13143411 - 7 Jul 2021
Cited by 7 | Viewed by 3086
Abstract
Supervised exercise and nutrition programs can mitigate or reverse androgen deprivation therapy (ADT) induced fat mass (FM) gain, lean mass (LM) loss, and impaired physical function. It is unclear whether these benefits are retained following transition to self-management. This study examined the effect [...] Read more.
Supervised exercise and nutrition programs can mitigate or reverse androgen deprivation therapy (ADT) induced fat mass (FM) gain, lean mass (LM) loss, and impaired physical function. It is unclear whether these benefits are retained following transition to self-management. This study examined the effect of a home-based weight maintenance program on body composition and physical function in obese men with prostate cancer (PCa) on ADT following a 12-week supervised weight loss intervention. Eleven obese PCa patients (74 ± 5 years, 40.0 ± 4.9% body fat) on ADT (>6 months) completed a 12-week self-managed home-based weight maintenance program consisting of 150 min/week of aerobic and resistance training while maintaining a healthy balanced diet. Body composition (DXA), muscle strength (1RM), and cardiorespiratory fitness (400 m walk) were assessed. Significant reductions in weight (−2.8 ± 3.2 kg) and FM (−2.8 ± 2.6 kg), preservation of LM (−0.05 ± 1.6 kg), and improvements in muscle strength and VO2max were achieved across the supervised intervention. Across the home-based program, no significant changes were observed in weight (−0.6 ± 2.8 kg, p = 0.508), FM (0.2 ± 1.4 kg, p = 0.619), LM (−0.8 ± 1.6 kg, p = 0.146), muscle strength (−0.2 to 4.1%, p = 0.086–0.745), or estimated VO2max (0.3 ± 2.1 mL/min/kg, p = 0.649). Self-managed, home-based exercise and nutrition programs are a viable strategy to promote maintenance of body composition and physical function following a supervised intervention in obese PCa patients on ADT. Full article
(This article belongs to the Special Issue Exercise and Nutrition in Cancer Care)
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