Epigenetic and Metabolic Alterations in the Tumor Microenvironment
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Pathophysiology".
Deadline for manuscript submissions: closed (30 April 2023) | Viewed by 26571
Special Issue Editors
Interests: autophagy and protein metabolism in cancer and in neurodegeneration; epigenetics in cancer; nutraceuticals and probiotics in cancer and infectious diseases
Special Issues, Collections and Topics in MDPI journals
Interests: cancer; cell signaling; non-coding RNA; tumor microenvironment
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cancer is an organoid in which parenchymal cancer cells are embedded together with several other cell types in a complex matrix in which the presence of nutrients, oxygen, and signaling molecules (cytokines, growth factors) is subjected to dynamic changes. The intercellular communications between malignant cancer cells and cancer-associated fibroblasts and immune cells present in the stroma lead to continuous remodeling of the tumor microenvironment, which then impinges on the progression of cancer. In this scenario, epigenetic changes caused by microenvironmental factors play a major role in metabolic reprogramming and, consequently, in the behavior of cancer cells.
In this Special Issue, we wish to collect original research and review articles addressing the epigenetic and metabolic alterations occurring in the tumor environment that influence cancer progression through impacting the proliferation, migration and invasion, dormancy, stemness, and resistance to therapy of cancer cells.
Prof. Dr. Ciro Isidoro
Prof. Dr. Danny N. Dhanasekaran
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- tumor microenvironment
- hypoxia
- inflammation
- cytokines
- epigenetics
- metabolic cross-talk
- cancer stroma cells
- epigenetic alterations
- cancer cell dormancy
- cancer cell proliferation
- cancer cell migration
- cancer cell stemness
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.