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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Peripheral Nerve Tumors
edited by
submission deadline 31 Jan 2027 | 1 articles | Viewed by 542 | Submission Open
Keywords: electrophysiology; malignant peripheral nerve sheath tumors; nerve sheath collision tumors; neurofibromas; neurofibromatosis type 1; NF2-associated schwannomatosis; non-NF2-associated schwannomatosis; schwannomas; untypical neurofibromas of uncertain biological potential
Digital Health and Patient-Reported Outcomes in Cancer Care
edited by Joanne Droney
submission deadline 31 Jan 2027 | Viewed by 288 | Submission Open
Keywords: patient-reported outcome measures; digital health; remote symptom monitoring; outcome-based healthcare; health-related quality of life (HRQoL); shared decision-making; real-world data collection; data standardization; health equity in digital health
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Machine Learning and Artificial Intelligence in Leukemia
edited by Garrett M. Dancik and
submission deadline 31 Jan 2027 | Viewed by 211 | Submission Open
Keywords: cancer genomics; genomic sequencing; biomarkers; predictive modeling; machine learning; artificial intelligence; leukemia; computer vision; natural language processing
(This special issue belongs to the Section Methods and Technologies Development)
Thoracic Surgical Oncology—Current Landscape and Future Directions
edited by Piergiorgio Solli and Alessia Stanzi
submission deadline 31 Jan 2027 | Viewed by 150 | Submission Open
Keywords: minimally invasive thoracic surgery; immunotherapy; liquid biopsy; lung cancer; mesothelioma; esophageal cancer; precision oncology
(This special issue belongs to the Section Clinical Research of Cancer)
Advances in the Use of PET/CT and MRI in Prostate Cancer: 2nd Edition
edited by Carmelo Caldarella
submission deadline 31 Jan 2027 | 1 articles | Viewed by 131 | Submission Open
Keywords: PET/CT; MRI; prostate cancer; radiomic; receptor-targeted radiopharmaceuticals
(This special issue belongs to the Section Methods and Technologies Development)
Advances in Molecular Biology and Genetics of Prostate Cancer submission deadline 31 Jan 2027 | Viewed by 87 | Submission Open
Keywords: prostate cancer; treatment resistance; tumor microenvironment; genomic alterations; therapy progression mechanisms
(This special issue belongs to the Section Molecular Cancer Biology)
Thyroid Cancer: Diagnosis, Prognosis and Treatment—3rd Edition submission deadline 31 Jan 2027 | Viewed by 73 | Submission Open
Keywords: thyroid cancer; ultrasound; molecular imaging; fine-needle aspiration cytology; thyroidectomy; radioactive iodine; radioiodine-refractory thyroid cancer; tyrosine kinase inhibitors
The Advance in Anticancer Drugs and Pharmacotherapy of Cancer
edited by
submission deadline 31 Jan 2027 | Viewed by 52 | Submission Open
Keywords: anticancer; therapeutics; target therapy; immune-oncology; mode of action; molecular mechanisms; targeted protein degradation; antibody-drug conjugates; cell therapy; cancer parmacology
(This special issue belongs to the Section Cancer Drug Development)
Molecular and Genetic Drivers of Cancer: Organelle Dysfunction, Cancer Stem Cells, and Tumor Progression
edited by and Maziar Ashrafian-Bonab
submission deadline 31 Jan 2027 | Viewed by 14 | Submission Open
Keywords: cancer progression; organelle dysfunction; cancer stem cells; mitochondria; microtubules; organelle crosstalk; tumor metabolism; therapeutic resistance
(This special issue belongs to the Section Molecular Cancer Biology)
Progress and Precision in Surgical Treatment for Hepatobiliary and Pancreatic Cancers
edited by Ajith K. Siriwardena, Samik Kumar Bandyopadhyay and Louise M. Finch
submission deadline 1 Feb 2027 | Viewed by 88 | Submission Open
Keywords: liver surgery; pancreas surgery; robotic surgery; ablation; irreversible electroporation; liver tumours
Digital Health Technologies in Oncology: 2nd Edition submission deadline 25 Feb 2027 | Viewed by 461 | Submission Open
Keywords: digital healthcare; digital health technologies; diagnosis; wearable devices; rehabilitation technologies; assistive technologies; robotic surgery; (remote) monitoring; precision medicine; data analytics; healthcare teleassistance; AI-driven diagnostics and monitoring; AI-driven analytics.
(This special issue belongs to the Section Methods and Technologies Development)
Transformative Genomic Technologies Shaping the Future of Precision Approaches for Haematological Malignancies submission deadline 28 Feb 2027 | 1 articles | Viewed by 1136 | Submission Open
Keywords: multi-omics; risk stratification; bioinformatics; AI/machine learning; hematological malignancies; biomarkers; targeted therapeutics; genomics; cancer cell biology
Cellular Senescence, Aging and the Tumor Microenvironment in Cancer
edited by Jabed Iqbal and Jeremy Wee Kiat Ng
submission deadline 28 Feb 2027 | 1 articles | Viewed by 424 | Submission Open
Keywords: aging; senescence; immunosenescence; SASP; tumor microenvironment; immunotherapy
(This special issue belongs to the Section Tumor Microenvironment)
Innovative Approaches of Multimodal Imaging of Cancer Characteristics in Nuclear Medicine submission deadline 28 Feb 2027 | Viewed by 270 | Submission Open
Keywords: multimodal imaging; molecular imaging; PET; SPECT; MRI; CT; ultrasound; optical imaging; cancer
(This special issue belongs to the Section Methods and Technologies Development)
Non-Coding RNAs in Bone Tumors: Pathogenesis, Diagnostic Biomarkers, and Therapeutic Perspectives
edited by Albert Roessner
submission deadline 28 Feb 2027 | Viewed by 106 | Submission Open
Keywords: bone tumors; non-coding RNAs; pathogenesis; biomarkers; non-coding RNA therapeutics
Feature Papers in Section “Methods and Technologies Development” in 2026 submission deadline 1 Mar 2027 | 2 articles | Viewed by 1473 | Submission Open
Keywords: artificial intelligence (AI); medical imaging; clinical diagnostics; oncology biomarkers; precision medicine; big data integration; early cancer detection; radiomics; therapy response prediction; translational technology
(This special issue belongs to the Section Methods and Technologies Development)
Advances in Endoscopic Management of Esophageal Cancer
edited by Hugo Uchima and
submission deadline 1 Mar 2027 | 1 articles | Viewed by 441 | Submission Open
Keywords: endoscopic submucosal dissection (ESD); esophageal squamous cell carcinoma; Barrett’ s esophagus
(This special issue belongs to the Section Cancer Therapy)
Precise and Personalized Radiation Therapy for Cancer Treatment
edited by Thomas Weissmann
submission deadline 1 Mar 2027 | Viewed by 157 | Submission Open
Keywords: radiation research; artificial intelligence; cancer; adaptive radiotherapy; stereotactic radiotherapy; radiotherapy; (radio)-immunotherapy; (radio)-chemotherapy; precision radiotherapy
(This special issue belongs to the Section Cancer Therapy)
Clinical, Immune, and Microbial Markers of Response to Systemic Therapy in Skin Cancer
edited by
submission deadline 14 Mar 2027 | Viewed by 189 | Submission Open
Keywords: melanoma; cutaneous squamous cell carcinoma; immunotherapy; immune checkpoint inhibitors; tumor microenvironment; microbiome; predictive biomarkers
Resistance in Lung Cancer
edited by Mohamed Gadelkarim
submission deadline 15 Mar 2027 | Viewed by 460 | Submission Open
Keywords: lung cancer; SCLC; NSCLC; drug resistance; genetic mutations; tumor microenvironment; EMT; biomarkers; targeted therapy; immunotherapy
(This special issue belongs to the Section Cancer Therapy)
The Critical Intersection of Tobacco Use and Cancer Care
edited by Irene Tamí-Maury
submission deadline 15 Mar 2027 | Viewed by 282 | Submission Open
Keywords: cancer; oncology settings; smoking; tobacco use; prevention; cessation
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Integrative Cancer Genomics: From Classical Cytogenetics to Emerging Molecular Technologies
edited by Ying S. Zou
submission deadline 15 Mar 2027 | Viewed by 88 | Submission Open
Keywords: integrative cancer genomics; cancer cytogenetics; molecular cytogenetics; chromosomal abnormalities; optical genome mapping; next-generation sequencing; nanopore sequencing; 3D/Hi-C technologies; structural variants; AI in cytogenetics; hematological malignancies; FISH; chromosomal microarray; solid tumors
(This special issue belongs to the Section Methods and Technologies Development)
Feature Papers in Section “Infectious Agents and Cancer” submission deadline 25 Mar 2027 | Viewed by 219 | Submission Open
Keywords: infectious agents; microbiota; biomarker; oncology; cancers
(This special issue belongs to the Section Infectious Agents and Cancer)
Reproductive and Hormonal Factors in Breast and Gynecological Cancers: Epidemiological, Pathological, Diagnostic, and Therapeutic Perspectives
edited by
submission deadline 30 Mar 2027 | Viewed by 93 | Submission Open
Keywords: breast cancer; gynecological cancers; reproductive factors; hormonal exposure; epidemiology; tumor pathology; molecular subtypes; biomarkers; early diagnosis; risk stratification; endocrine therapy; targeted therapy; treatment resistance; personalized medicine
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Genome Instability, Ubiquitin Signaling and Cancer Therapy
edited by and Aftab Alam
submission deadline 30 Mar 2027 | Viewed by 82 | Submission Open
Keywords: DNA damage response; DNA repair; replication stress; ubiquitin– proteasome system; E3 ubiquitin ligases; targeted protein degradation; cell cycle checkpoints; drug resistance
Advances in Biomarker-Driven Targeted Therapies for Cancer: 2nd Edition
edited by
submission deadline 31 Mar 2027 | Viewed by 151 | Submission Open
Keywords: biomarkers; targeted therapies; precision medicine; cancer treatment; molecular profiling; personalized medicine; genomic alterations; therapeutic interventions; tumor microenvironment; immune therapy
(This special issue belongs to the Section Cancer Therapy)
Advanced Imaging and AI in Head and Neck Oncology
edited by
submission deadline 31 Mar 2027 | Viewed by 136 | Submission Open
Keywords: head and neck cancer; artificial intelligence; machine learning; advanced imaging; biomarker development; multimodal data integration; precision oncology; treatment toxicity; large language model; radiomics
Surgical Strategies in Neuro-Oncology: Optimizing Outcomes for Brain and Spinal Tumors
edited by
submission deadline 31 Mar 2027 | Viewed by 132 | Submission Open
Keywords: neuro-oncology; brain tumors; glioma; glioblastoma; brain metastases; spinal tumors; spinal metastases; neurosurgery; surgical strategy; outcome research
(This special issue belongs to the Section Cancer Therapy)
The Multimodal Management of Advanced Breast Cancers: Integrating Surgery, Radiation, and Systemic Therapies
edited by and Hope S. Rugo
submission deadline 31 Mar 2027 | Viewed by 129 | Submission Open
Keywords: metastatic breast cancer; inflammatory breast cancer; lobular breast cancer; de-escalation; breast sarcoma
(This special issue belongs to the Section Cancer Therapy)
Radiotherapy for Sarcomas and Connective Tissue Tumors
edited by Kevin X. Liu and Fantine N. Giap
submission deadline 31 Mar 2027 | Viewed by 105 | Submission Open
Keywords: radiotherapy; sarcoma; connective tissue tumors; proton radiotherapy; oligometastatic disease; palliative radiotherapy; radiation toxicity
Advances in Skin Cancer Diagnosis and Management
edited by Vlad Mihai Voiculescu
submission deadline 31 Mar 2027 | Viewed by 92 | Submission Open
Keywords: skin cancer; diagnosis; treatment; artificial intelligence; dermatological imaging
Advanced Diagnostics and Optical Imaging Technologies in Cancer Research (2nd Edition)
edited by Vlad Mihai Voiculescu
submission deadline 31 Mar 2027 | Viewed by 86 | Submission Open
Keywords: digital diagnostics; advanced diagnostics; optical imaging; medical images; artificial intelligence; image analysis; laser technologies
Pregnancy and Breast Cancer: Distinguishing Breast Cancer During Pregnancy, Post-Partum Breast Cancer (PPBC) and the Impact Breastfeeding
edited by Doris Germain
submission deadline 31 Mar 2027 | Viewed by 67 | Submission Open
Keywords: post-partum breast cancer; pregnancy; mammary gland involution; breastfeeding; lactation; parity; SEMA7A; PAPP-A; COX2
Advances in Immunotherapy and Targeted Therapy for Lung Cancer
edited by
submission deadline 3 Apr 2027 | Viewed by 156 | Submission Open
Keywords: thoracic oncology; immune checkpoint inhibitor; antibody-drug conjugate; bispecific antibody; targeted therapy; precision medicine; combination therapy; biomarker
(This special issue belongs to the Section Cancer Therapy)
Emerging Biomarkers for Immune Checkpoint Inhibitor Sensitivity and Resistance in Non-Small-Cell Lung Cancer
edited by Minglei Zhuo
submission deadline 20 Apr 2027 | Viewed by 385 | Submission Open
Keywords: non-small-cell lung cancer; immune checkpoint inhibitors; immunotherapy resistance; predictive biomarkers; tumor microenvironment; PD-L1; circulating biomarkers; microbiota; translational oncology; combination strategies
(This special issue belongs to the Section Cancer Biomarkers)
Interrogating Molecular Regulators and Chemical Agents in Brain Tumor Progression
edited by Shilpi Singh
submission deadline 30 Apr 2027 | 2 articles | Viewed by 6048 | Submission Open
Keywords: brain tumor progression; molecular mechanisms; small molecule inhibitors; natural compounds; synthetic drugs; biomarkers; oncogenic pathways; metabolic reprogramming
(This special issue belongs to the Section Tumor Microenvironment)
Advances in Supportive Care in Radiation Oncology
edited by Lukas Käsmann
submission deadline 30 Apr 2027 | Viewed by 94 | Submission Open
Keywords: supportive care; radiation oncology; symptom management; patient-reported outcomes; radiation dermatitis; oral mucositis; cancer survivorship; integrative oncology; quality of life
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
The Relationship Between Cancers Metabolism and Immunotherapy
edited by Suguru Saito
submission deadline 30 Apr 2027 | Viewed by 22 | Submission Open
Keywords: anti-tumor immunity; metabolism; immunotherapy; macrophages; T cells; exhaustion
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
The Role of Physical Activity in Cancer Prevention, Treatment and Rehabilitation submission deadline 1 May 2027 | Viewed by 77 | Submission Open
Keywords: cancer; hematooncology; adults; children; physical activity; exercise; interventions; supportive care; prevention; recovery; quality of life
New Statistical and Machine Learning Methods for Cancer Research
edited by Anjishnu Banerjee
submission deadline 20 May 2027 | 1 articles | Viewed by 1009 | Submission Open
Keywords: statistical methods; machine learning; “Omics” research; adaptive clinical trials; drug development; personalized cancer therapies
(This special issue belongs to the Section Cancer Informatics and Big Data)
Integrating Molecular and Conventional Diagnostics in Thyroid Nodule Management: Implications for Cancer Diagnosis and Treatment
edited by and Yanhua Bai
submission deadline 30 May 2027 | 1 articles | Viewed by 116 | Submission Open
Keywords: thyroid carcinoma; low-risk neoplasm; indeterminate thyroid nodule; molecular testing; ultrasound; FNA cytology; integrated risk stratification; multidisciplinary team discussion; active surveillance; conservative management
Radiation Therapy for Pediatric Cancers: Precision Techniques, Late Effects, and Survivorship Strategies submission deadline 31 May 2027 | Viewed by 174 | Submission Open
Keywords: pediatric radiation therapy; pediatric proton therapy; adaptive radiation therapy; advances in treatment planning and delivery; boron neutron capture therapy; molecularly targeted radiation therapy; late effects and survivorship; neurocognitive preservation; radiation-induced secondary malignancies; radiobiology of developing tissues; intellectual changes; cognitive outcomes
(This special issue belongs to the Section Pediatric Oncology)
The 5th International Electronic Conference on Cancers (IECC 2026)
edited by
submission deadline 30 Jun 2027 | Viewed by 223 | Submission Open
Keywords: cancer stem cells; tumor heterogeneity; drug resistance and anti-cancer drug development and screening; cancer survivorship and quality of life; causes; diagnosis; and treatment of cancer; patterns and treatment considerations of childhood cancer; novel methods and technologies for research and treatment
Primary, Secondary, and Tertiary Prevention Strategies in Head and Neck Cancer submission deadline 31 Jul 2027 | 1 articles | Viewed by 1024 | Submission Open
Keywords: head and neck cancer; oral cavity cancer; oral squamous cell carcinoma; oral potentially malignant disorders; oral leukoplakia; erythroplakia; proliferative verrucous leukoplakia; oral mucositis; radiodermatitis; osteoradionecrosis; radiation caries; trismus; quality of life; survival
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Cancer Causes and Control submission deadline 1 Dec 2027 | 5 articles | Viewed by 17171 | Submission Open
Keywords: cancer burden; risk factors for cancer; primary cancer prevention; secondary cancer prevention; tertiary cancer prevention; quality of life for people who have cancer; population-based cancer registry
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
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