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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Gynecological Oncology: From Pathogenesis to Therapy: 2nd Edition

edited by

Andrea Ciavattini

submission deadline 18 Dec 2024 | 2 articles | Viewed by 1856

Keywords: ovarian cancer; uterine cancer; cervical cancer; vulvar cancer; biomarkers; HPV vaccine; sentinel lymph node evaluation; fertility-sparing treatment; recurrent gynecological cancer; molecular profile; immunotherapy; chemotherapy; radiotherapy; hormonal therapy; imaging

(This special issue belongs to the Section Cancer Therapy)

Current Epidemiologic, Diagnostic, and Therapeutic Aspects of Cholangiocarcinoma (CCA)

edited by

Sven Loosen

and

Christoph Roderburg

submission deadline 20 Dec 2024 | 16 articles | Viewed by 37696 | Submission Open

Keywords: Biliary tract cancer; BTC; liver cancer; immunotherapy; biomarkers; prognosis; therapy

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Molecular Mechanisms of Cancer Development and Metastasis

edited by

Babak Behnam

and Hassan Fazilaty

submission deadline 20 Dec 2024 | 8 articles | Viewed by 15593 | Submission Open

Keywords: cancer microenvironment; metastatic pathway; cancer stem cell; Epithelial-to-mesenchymal transition; EMT; Cell invasion; Immune evasion; Cell plasticity; Cell migration

(This special issue belongs to the Section Cancer Metastasis)

The Current Status of Brain Tumors Imaging

edited by

Houman Sotoudeh

submission deadline 20 Dec 2024 | 5 articles | Viewed by 11412 | Submission Open

Keywords: neuro-oncology; glioma; brain metastasis; CT Scan; MRI; radiogenomics; radiomics; artificial intelligence; MR spectroscopy; MR perfusion; fMRI

(This special issue belongs to the Section Methods and Technologies Development)

Adaptive Resistance to Targeted Cancer Therapies and Rational Development of Combination Therapies

edited by

Andrea Rocca

and

Boris Kholodenko

submission deadline 20 Dec 2024 | 7 articles | Viewed by 10455 | Submission Open

Keywords: targeted therapies; cancer drug resistance; adaptive resistance; signal transduction networks; network adaptation; cell state transitions

(This special issue belongs to the Section Cancer Therapy)

Autophagy–EMT Interrelations: At the Core of Tumor Transformation

edited by

Marco Cordani

Miguel Sánchez Álvarez

Raffaele Strippoli

Stefania Meschini

and

Maria Condello

submission deadline 20 Dec 2024 | 3 articles | Viewed by 10027 | Submission Open

Keywords: autophagy; EMT; TGF-beta; cytoskeleton; mitochondria; signaling pathways; cancer progression

(This special issue belongs to the Section Tumor Microenvironment)

Evolving Trends in the Surgical Therapy of Patients with Gynecological Cancer

edited by Jacobus van der Velden

submission deadline 20 Dec 2024 | 3 articles | Viewed by 4509 | Submission Open

Keywords: endometrial cancer; ovarian cancer; vulvar cancer; cervix cancer; resection margin; bulky lymph node; parametrectomy; debulking; preservation ovary; minimally invasive surgery

(This special issue belongs to the Section Cancer Therapy)

Optimizing Surgical Procedures and Outcomes in Renal Cancer

edited by

Maciej Salagierski

and Piotr Kania

submission deadline 20 Dec 2024 | 3 articles | Viewed by 3090 | Submission Open

Keywords: renal cancer surgery; optimizing outcomes; minimally invasive techniques; surgical innovations; multidisciplinary approaches

(This special issue belongs to the Section Clinical Research of Cancer)

Recent Advances in Deep Learning and Medical Imaging for Cancer Treatment (Volume II)

edited by

Marcin Woźniak

and

Muhammad Fazal Ijaz

submission deadline 20 Dec 2024 | 2 articles | Viewed by 2990 | Submission Open

Keywords: deep learning; machine learning; medical imaging; bioimaging; computer-aided diagnosis oncology

(This special issue belongs to the Section Cancer Therapy)

Novel Therapeutic Targets and Management in Pediatric Cancer

edited by

Péter Hauser

submission deadline 20 Dec 2024 | 1 articles | Viewed by 1468 | Submission Open

Keywords: pediatric tumor; pediatric brain tumor; bone tumor; neuroblastoma; targeted treatment; immunotherapy; predisposition syndrome

(This special issue belongs to the Section Cancer Therapy)

Brain Tumours: Advances in Imaging-Guided Diagnosis, Surveillance and Therapy

edited by

Sotirios Bisdas

submission deadline 20 Dec 2024 | 1 articles | Viewed by 1360 | Submission Open

Keywords: brain tumour; neuro-oncology; MRI; CT; PET; gliomas; glioblastomas; advanced imaging; imaging biomarkers; neurosurgery; immunotherapy; clinical trials; radiation therapy; chemotherapy; precision medicine; tumour biology; AI

(This special issue belongs to the Section Cancer Biomarkers)

Drug Combination Therapy of Glioblastoma

edited by

Ewa Obuchowicz

and

Anna Bielecka-Wajdman

submission deadline 20 Dec 2024 | Viewed by 422 | Submission Open

(This special issue belongs to the Section Cancer Drug Development)

Immunotherapy in Non-Small Cell Lung Cancers

edited by Marco Russano

submission deadline 22 Dec 2024 | Viewed by 216 | Submission Open

Keywords: non-small cell lung cancer; immune checkpoint inhibitors; PD-1/PD-L1 blockade; immunotherapy; biomarkers

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Rare Breast Tumors

edited by

Maggie Banys-Paluchowski

and

Maria Luisa Gasparri

submission deadline 23 Dec 2024 | 3 articles | Viewed by 3187 | Submission Open

Keywords: rare breast tumors; rare histology; breast cancer; phylloides tumor; male breast cancer; CUP syndrome; breast implant-associated anaplastic large cell lymphoma; diabetic mastopathy; metaplastic breast cancer; apocrine breast cancer; inflammatory breast cancer; medullary breast cancer; mucinous breast cancer; adenoid cystic carcinoma of the breast; lymphoma of the breast; basal type breast cancer; angiosarcoma of the breast breast neuroendocrine tumors; brain metastases; PET imaging agents (FES; FFNP; and FDHT); microinvasive breast cancer; supraclavicular and contralateral axillary lymph node involvement; ectopic breast tissue; pregnancy-associated breast cancer

(This special issue belongs to the Section Cancer Therapy)

Pediatric Cancers: Insights and Novel Therapeutic Approaches

edited by

Saurabh Agarwal

submission deadline 24 Dec 2024 | 1 articles | Viewed by 2380 | Submission Open

Keywords: pediatric cancer; immunotherapy; tumorigenesis; metastasis; relapse; small molecule inhibitors; therapeutics; chemotherapy; cell signaling; epigenetics

(This special issue belongs to the Section Cancer Therapy)

Advances in the Diagnosis, Prognosis and Treatment of Diffuse Large B-cell Lymphoma

edited by

Gustavo Tapia

submission deadline 25 Dec 2024 | 5 articles | Viewed by 13344 | Submission Open

Keywords: no-Hodgkin lymphoma; diffuse large B-cell lymphoma; DLBCL; lymphoma treatment; lymphoma diagnosis; lymphoma prognosis; lymphoma biology

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Tumor Immune Microenvironment in Gastric Cancers

edited by

Chandrani Sarkar

and

Debanjan Chakroborty

submission deadline 25 Dec 2024 | 4 articles | Viewed by 11477 | Submission Open

Keywords: tumor immune microenvironment; gastric cancer; therapeutic strategies; therapeutic response; tumor-associated macrophages

(This special issue belongs to the Section Tumor Microenvironment)

Mantle Cell Lymphoma: From Biology to Therapy

edited by

Narendranath Epperla

submission deadline 25 Dec 2024 | 1 articles | Viewed by 2938 | Submission Open

Keywords: MCL; biology; BTK inhibitors; BCL2 inhibitors; CART; bispecific antibodies

(This special issue belongs to the Section Molecular Cancer Biology)

The Role of Genes in Prostate Cancer

edited by Olivier Cussenot

submission deadline 25 Dec 2024 | 1 articles | Viewed by 1436 | Submission Open

Keywords: prostate cancer; genes; microenvironment

(This special issue belongs to the Section Tumor Microenvironment)

Research on Cell Death in Cancer Immunotherapy

edited by Henning Walczak

submission deadline 25 Dec 2024 | Viewed by 225 | Submission Open

Keywords: TNF; FasL; TRAIL; death receptor– ligand systems; LUBAC; RNF31; cIAP1/2; TBK1; IKK; RIPK1; RIPK3; apoptosis; necroptosis; pyroptosis; ferroptosis

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Pathogenesis of Non-alcoholic Steatohepatitis (NASH)-Related Hepatocellular Carcinoma (HCC)

edited by Kathryn Effendi

submission deadline 27 Dec 2024 | 3 articles | Viewed by 6875 | Submission Open

Keywords: hepatocellular carcinoma; non-alcoholic fatty liver disease; metabolic syndrome; fibrosis; chronic inflammation; biomarkers; pathogenesis; immune microenvironment

(This special issue belongs to the Section Cancer Pathophysiology)

Advances in Cancer Data and Statistics

edited by

Vesna Zadnik

submission deadline 30 Dec 2024 | 11 articles | Viewed by 20320 | Submission Open

Keywords: cancer registries; cancer incidence; cancer survival; population-based studies; cancer risk factors

(This special issue belongs to the Section Cancer Informatics and Big Data)

Towards a Tailored Treatment of Chronic Lymphocytic Leukemia

edited by

Antonio Cuneo

, Paolo Prospero Ghia, Francesca Romana Mauro,

Marta Coscia

and

Gianluca Gaidano

submission deadline 30 Dec 2024 | 2 articles | Viewed by 5885 | Submission Open

Keywords: chronic lymphocytic leukemia; treatment; targeted therapy; immunotherapy; adverse events; prognosis; resistance; MR

(This special issue belongs to the Section Cancer Therapy)

Multimodal Treatment for Pancreatic Cancer

edited by

Cosimo Sperti

submission deadline 30 Dec 2024 | 2 articles | Viewed by 2251 | Submission Open

Keywords: pancreatic cancer; multimodal therapy; neoadjuvant therapy; surgery of pancreatic cancer; surgical complications; response to therapy; survival; recurrence; loco-regional therapy; novel therapies

(This special issue belongs to the Section Cancer Therapy)

Novel Computational Approaches for Molecular Target Discovery in Colorectal Cancer

edited by

Giovanni Crisafulli

submission deadline 30 Dec 2024 | 1 articles | Viewed by 1924 | Submission Open

Keywords: colorectal cancer; genetics; bioinformatics; therapeutic targets; cancer evolution; personalized medicine; patient stratification; technological advancements; precision oncology; big data; computational approach

(This special issue belongs to the Section Methods and Technologies Development)

Advance in Hepatopancretobiliary Cancers: A Themed Issue in Honor of Prof. Dr. Timothy M. Pawlik

edited by Gaya Spolverato

submission deadline 30 Dec 2024 | 1 articles | Viewed by 1021 | Submission Open

Keywords: hepatobiliary surgery; pancreatic cancer; liver surgery; neuroendocrine tumors; surgical oncology; cancer prognosis

Epigenetics and Transcription Networks in Leukemia

edited by

Yi Qiu

submission deadline 30 Dec 2024 | Viewed by 474 | Submission Open

Keywords: leukemia; epigenetics; gene regulation; genetic mutation; chemoresistance; therapy

(This special issue belongs to the Section Cancer Pathophysiology)

Cancer Stem Cells in Major Smoking Related Cancers

edited by

Mohammad O. Hoque

and

Pritam Sadhukhan

submission deadline 30 Dec 2024 | Viewed by 359 | Submission Open

Keywords: cancer stem cells; cancer recurrence; therapeutic resistance; tumor microenvironment; cancer signaling pathways; targeted therapy; head and neck cancer; lung cancer; bladder cancer; esophageal cancer; pancreatic cancers; kidney cancer; cervical cancer

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Surgery for Gastrointestinal Cancers: From Predictive and Prognostic Biomarkers to Advances in the Prevention of Complications and Improvement of Oncological Outcomes

edited by Michail Pitiakoudis

submission deadline 30 Dec 2024 | Viewed by 191 | Submission Open

Keywords: biomarkers; complications; prognosis; gastrointestinal cancer surgery; gastrointestinal cancer; surgical oncology; fluorescence-guided surgery; metastases; quality of life; outcomes

(This special issue belongs to the Section Clinical Research of Cancer)

Anticancer Drug Discovery Based on Natural Products: From Computational Approaches to Clinical Studies

edited by

Rajeev K. Singla

and

Anupam Bishayee

submission deadline 31 Dec 2024 | 10 articles | Viewed by 27180 | Submission Open

Keywords: natural compounds; cancer; anticancer effects; cytotoxic agents; cheminformatics; plant secondary metabolites; malignant tumor; drug resistance; hallmark traits; molecular mechanisms

(This special issue belongs to the Section Cancer Drug Development)

Novel Insights into Glioblastoma and Brain Metastases

edited by

Sanjay K. Srivastava

submission deadline 31 Dec 2024 | 9 articles | Viewed by 17989 | Submission Open

Keywords: glioblastoma; brain metastasis; surgery; radiation; chemotherapy; blood– brain barrier; immunotherapy; novel targets; oncogenes; tumor heterogeneity; drug discovery

(This special issue belongs to the Section Cancer Metastasis)

MRI in Prostate Cancer

edited by

Milica Medved

and

Aritrick Chatterjee

submission deadline 31 Dec 2024 | 11 articles | Viewed by 16740 | Submission Open

Keywords: MRI; prostate cancer; screening; diagnosis; treatment

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Advanced Strategies in the Care of Hepatocellular Carcinoma Patients

edited by

Matteo Donadon

and

Guido Torzilli

submission deadline 31 Dec 2024 | 7 articles | Viewed by 15529 | Submission Open

Keywords: hepatocellular carcinoma; hepatic resection; hepatectomy; liver resection; liver surgery; parenchymal-sparing liver surgery; intraoperative ultrasound; liver-specific magnetic resonance imaging; trans-arterial therapy; liver function; FibroScan

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Feature Paper in Section “Cancer Therapy” in 2024

edited by

Abdullah Esmail

and Ala Abudayyeh

submission deadline 31 Dec 2024 | 11 articles | Viewed by 14524 | Submission Open

Keywords: chemotherapy; immunotherapy for cancer; oncology; systemic treatment and targeted therapy

(This special issue belongs to the Section Cancer Therapy)

Oesogastric Cancer: Treatment and Management

edited by Arnaud Pasquer

submission deadline 31 Dec 2024 | 7 articles | Viewed by 14432 | Submission Open

Keywords: oesophagus cancer; gastric cancer; laparoscopy; robotic surgery; neoadjuvant treatment; immunotherapy; carcinosis; HIPEC; PIPAC

(This special issue belongs to the Section Cancer Therapy)

Feature Paper in Section 'Cancer Epidemiology and Prevention' in 2024

edited by Roger Anderson and

Paweł Koczkodaj

submission deadline 31 Dec 2024 | 10 articles | Viewed by 14384 | Submission Open

Keywords: cancer prevention; cancer epidemiology; health policy; public health; global health; health education; health promotion

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Feature Papers in Section "Cancer Biomarkers" in 2023–2024

edited by

Maxim V. Berezovski

submission deadline 31 Dec 2024 | 11 articles | Viewed by 12914 | Submission Open

Keywords: RNA and miRNA biomarkers; DNA biomarkers; cell-free DNA; protein biomarkers; metabolomic biomarkers; mutational biomarkers; circulating tumor cell (CTC) biomarkers; tumor-derived extracellular vesicle (tEV) biomarkers; cellular biomarkers; imaging biomarkers; clinical biomarkers; biomarkers of drug response; biomarkers of genetic predisposition to cancer; epigenetic biomarkers; biomarkers of cancer outcomes

(This special issue belongs to the Section Cancer Biomarkers)

Cervical Cancer: Screening and Treatment in 2024

edited by

Fabrice Lécuru

and

Benedetta Guani

submission deadline 31 Dec 2024 | 5 articles | Viewed by 12750 | Submission Open

Keywords: cervical cancer; fertility sparing; screening; early stage cervical cancer; locally advanced cervical cancer; sentinel lymph node; staging lymphadenectomy; trachelectomy; immunotherapy in cervical cancer; target therapy in cervical cancer

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Brain and Spinal Cord Tumors: Symptoms, Diagnosis, and Treatment

edited by

Alberto Feletti

and

Takashi Sugawara

submission deadline 31 Dec 2024 | 7 articles | Viewed by 11950 | Submission Open

Keywords: brain; spinal cord; primary tumors; metastases; imaging; neuro-oncology

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Immune Checkpoint Inhibitors for Urologic Cancers

edited by

Panagiotis Vlachostergios

submission deadline 31 Dec 2024 | 6 articles | Viewed by 11683 | Submission Open

Keywords: identification of biomarkers for prostate; kidney and bladder cancer; neuroendocrine prostate cancer; PSMA theranostics; upper tract urothelial carcinoma; treatment-resistant urothelial carcinoma; genomics and immunogenomics for urological cancers

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Diagnosis and Staging of Gastroesophageal Cancer

edited by

and

submission deadline 31 Dec 2024 | 4 articles | Viewed by 11326 | Submission Open

Keywords: gastric cancer; esophageal cancer; current diagnosis of gastroesophageal cancer; indocyanine green; artificial intelligence; radiomics; staging laparoscopy

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Molecular Markers and Targeted Therapy for Hepatobiliary Tumors

edited by Masaki Kuwatani

submission deadline 31 Dec 2024 | 5 articles | Viewed by 9964 | Submission Open

Keywords: cholangiocarcinoma; hepatocellular carcinoma; molecule; gene; chemotherapy; phototherapy

(This special issue belongs to the Section Cancer Therapy)

Differential Scanning Calorimetry and Related Thermal Analysis Techniques as Complementary Approaches for Cancer Diagnosis, Prognosis, Monitoring and Assessment of Treatment Response

edited by

Nichola C. Garbett

submission deadline 31 Dec 2024 | 5 articles | Viewed by 9754 | Submission Open

Keywords: differential scanning calorimetry; differential scanning fluorimetry; thermal analysis; clinical diagnostics; biospecimen; diagnosis; prognosis; monitoring; treatment; diagnostic performance

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Current Progress and Research Trends in Ocular Oncology

edited by Utta Berchner-Pfannschmidt,

Miltiadis Fiorentzis

and Nikolaos E. Bechrakis

submission deadline 31 Dec 2024 | 7 articles | Viewed by 9739 | Submission Open

Keywords: ocular oncology; uveal melanoma; conjunctival melanoma; retinoblastoma; primary tumor; recurrence; metastasis; oncogenic pathways; genetic and cellular heterogeneity; cancer immunity; diagnostic strategies; therapeutic options

(This special issue belongs to the Section Cancer Therapy)

Advances in Chronic Lymphocytic Leukaemia (CLL) Research

edited by

H. Denis Alexander

submission deadline 31 Dec 2024 | 4 articles | Viewed by 9535 | Submission Open

Keywords: chronic lymphocytic leukaemia; CLL; aetiology; oncogenic transformation; survival; cure

(This special issue belongs to the Section Cancer Therapy)

Diagnosis and Treatment for Hepatocellular Tumors (Volume II)

edited by

Georgios Germanidis

and Dimitris C. Zacharoulis

submission deadline 31 Dec 2024 | 5 articles | Viewed by 9487 | Submission Open

Keywords: HCC; diagnosis; BCLC-B; BCLC-C; anti-PD-1/PD-L1 immunotherapy; TKIs; combinations; TME; addiction loops; interventions; established data; neoadjuvant treatment; adjuvant treatment; definitive surgical treatment

(This special issue belongs to the Section Cancer Therapy)

Advances in Genomics and Molecular Pathology of Rare Cancers—Focus on Diverse Populations

edited by

Yong Sheng Jason Chan

submission deadline 31 Dec 2024 | 4 articles | Viewed by 9189 | Submission Open

Keywords: soft tissue sarcoma; bone sarcoma; lymphoma; melanoma; adolescent and young adult oncology; global oncology; multi-omics; immunotherapy; targeted therapy; oncopathogens

(This special issue belongs to the Section Cancer Pathophysiology)

Advanced Diagnostics and Optical Imaging Technologies in Cancer Research

edited by Vlad Mihai Voiculescu

submission deadline 31 Dec 2024 | 6 articles | Viewed by 8660 | Submission Open

Keywords: digital diagnostics; advanced diagnostics; optical imaging; medical images; artificial intelligence; image analysis; laser technologies

(This special issue belongs to the Section Methods and Technologies Development)

Disparities in Cancer Prevention, Screening, Diagnosis and Management

edited by Eliza W. Beal

submission deadline 31 Dec 2024 | 7 articles | Viewed by 8227 | Submission Open

Keywords: social determinants of health (SDOH); financial toxicity; racial disparities; ethnic disparities; LGBTQIA+ disparities; cultural competency; cancer; health status disparities; healthcare disparities

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Advances in Survival of Glioblastoma

edited by

Ondrej Kalita

and

Tomas Kazda

submission deadline 31 Dec 2024 | 3 articles | Viewed by 7242 | Submission Open

Keywords: glioblastoma; oncotherapy; life expectancy; overall survival; quality of life

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

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