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Cells publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Antithrombotic Research: From Pharmacological Mechanisms to Innovative Approaches

edited by

Pierpaolo Di Micco

Vincenzo Russo

and

Egidio Imbalzano

submission deadline 10 Aug 2024 | 2 articles | Viewed by 19324 | Submission Open

Keywords: atherothrombosis; thromboembolic cardiac embolism; unusual site of thrombosis; venous thromboembolism; thrombophilia; acute antithrombotic treatment; chronic long-term antithrombotic treatment; antithrombotics; antiplatelets; anticoagulants; warfarin; heparins; low molecular weight heparins; direct oral anticoagulants; aspirin; ticagrelor; clopidogrel; statins; PCSK9 inhibitors; immunomodulant therapy; evolocumab; alirocumab; eltrombopag

Cell and Immune Therapeutics for Gliomas

edited by

John I. Bianco

and

Steven Brem

submission deadline 10 Aug 2024 | 1 articles | Viewed by 4047 | Submission Open

Keywords: immune modulation; T-cell activation; tumour-associated macrophages; tumour microenvironment; stem cells

(This special issue belongs to the Section Cell Microenvironment)

The Role of Inflammation in Atherosclerosis and Coronary Artery Disease—2nd Edition

edited by

Weibin Shi

submission deadline 10 Aug 2024 | Viewed by 189 | Submission Open

Keywords: atherosclerosis; coronary artery disease; inflammation; cytokines; white blood cells; monocyte; macrophage; adhesion molecule; chemokines; thrombosis; diabetes

(This special issue belongs to the Section Cells of the Cardiovascular System)

New Insights into Adipose-Derived Stem Cells (ADSCs)

edited by

Francesco De Francesco

Arthi Shridhar

and William D’Angelo

submission deadline 15 Aug 2024 | 2 articles | Viewed by 4946 | Submission Open

Keywords: adipose-derived stem cells; immunomodulation; exosomes; cell therapy; clinical translation

(This special issue belongs to the Section Stem Cells)

Non-coding RNAs: Multiple Players in Human Diseases

edited by

Yujing Li

submission deadline 15 Aug 2024 | 2 articles | Viewed by 3023 | Submission Open

Keywords: non-coding RNA; human disease; epigenetic marker; therapy; pathogenesis; transcriptome

(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)

Cellular and Molecular Mechanisms of Multiple Drug Resistance (MDR)

edited by

and

submission deadline 15 Aug 2024 | 1 articles | Viewed by 1859 | Submission Open

Keywords: multidrug resistance (MDR); detoxification; cellular drug modification/elimination; ER stress; cell death; DNA repair; epigenetics regulation

Novel Mechanisms of Gene Regulation in Cardiac Development and Congenital Heart Defects

edited by

Marlin Touma

submission deadline 15 Aug 2024 | Viewed by 200 | Submission Open

Keywords: long noncoding RNA; epigenetic regulation; whole-genome sequencing; cardiomyocyte signaling; cardiovascular development ; congenital heart defects

(This special issue belongs to the Section Cells of the Cardiovascular System)

Autophagosome Formation

edited by Yan Zhen and Ikuko Koyama-Honda

submission deadline 15 Aug 2024 | Viewed by 195 | Submission Open

Keywords: ATG2; ATG9; autophagosome; endosome; membrane contact site; omegasome; phagophore; lipid channel; lipid scramblase

(This special issue belongs to the Section Autophagy)

Molecular Mechanism of Bone Disease

edited by

Maria Teresa Valenti

and

Roberta Zerlotin

submission deadline 20 Aug 2024 | 2 articles | Viewed by 1517 | Submission Open

Keywords: bone; mesenchymal stem cells; transcription factors; bone rare diseases; skeletal degenerative diseases

(This special issue belongs to the Section Cellular Pathology)

Brain Tumors: From Neuropathology to Molecular Biology

edited by

Francesco Maiuri

, Marialaura Del Basso De Caro and

Lorenzo Chiariotti

submission deadline 20 Aug 2024 | Viewed by 333 | Submission Open

Keywords: brain tumor pathology; neuro-oncology; molecular biology; immunohistochemistry; histopathology

(This special issue belongs to the Section Cellular Pathology)

Molecular and Cellular Mechanisms on Plant Polyphenols

edited by

Monica Bucciantini

and

Manuela Leri

submission deadline 20 Aug 2024 | Viewed by 259 | Submission Open

Keywords: natural polyphenols; cell homeostasis; anti-oxidant; anti-inflammatory; health effects

(This special issue belongs to the Section Plant, Algae and Fungi Cell Biology)

Kidney Disease Models, Cellular Mechanism and Potential Treatment

edited by

Nicole Endlich

submission deadline 20 Aug 2024 | Viewed by 194 | Submission Open

Keywords: kidney disease; signaling pathways; therapy; biomarker; prevention

(This special issue belongs to the Section Tissues and Organs)

Regulation of Fibroblasts and Fibrosis in Cardiovascular Disease

edited by

Wayne Carver

submission deadline 20 Aug 2024 | Viewed by 133 | Submission Open

Keywords: fibrosis; fibroblasts; cardiovascular; inflammation; extracellular matrix; collagen

(This special issue belongs to the Section Cells of the Cardiovascular System)

Inflammation in Target Organs

edited by

Itamar Raz

and Roni Weinberg Sibony

submission deadline 29 Aug 2024 | 2 articles | Viewed by 3046 | Submission Open

Keywords: inflammation; fibrosis; cardio-renal; vascular; liver; brain

(This special issue belongs to the Section Cellular Immunology)

Fat Is a Matter? The Implication of Adipose Tissue in Cardiovascular Health and Disease

edited by

Sang Woo Kim

submission deadline 30 Aug 2024 | 4 articles | Viewed by 9722 | Submission Open

Keywords: adipose tissue; adipocyte; cardiovascular disease; metabolic disease; energy homeostasis

(This special issue belongs to the Section Cellular Metabolism)

Regulatory T Cells and Autoimmunity

edited by Fan Pan

submission deadline 30 Aug 2024 | 2 articles | Viewed by 3062 | Submission Open

Keywords: regulatory T cells; immune tolerance; Foxp3; autoimmune disease (AD); immunotherapy

(This special issue belongs to the Section Cellular Immunology)

Pluripotent Stem Cells: Current Applications and Future Directions

edited by

Julie Bejoy

submission deadline 30 Aug 2024 | 1 articles | Viewed by 1512 | Submission Open

Keywords: induced pluripotent stem cells; organoids; reprogramming; differentiation; spheroids; cortical organoids; intestinal organoids; kidney organoids; cardiomyocytes; astrocytes; microglia; personalized medicine; drug screening; disease modeling

(This special issue belongs to the Section Stem Cells)

Focus on Redox Signaling

edited by

Valentina Bosello-Travain

submission deadline 30 Aug 2024 | 1 articles | Viewed by 1276 | Submission Open

Keywords: redox signaling; oxidative stress; reactive oxygen species (ROS); reactive molecules; cellular signaling; human diseases

(This special issue belongs to the Section Cell Signaling)

Multifaceted Roles of Mesenchymal Stem Cells in Health and Disease

edited by

Agnieszka Mikłosz

and Bartłomiej Łukaszuk

submission deadline 30 Aug 2024 | Viewed by 268 | Submission Open

Keywords: diabetes mellitus; dyslipidemia; insulin resistance; metabolic syndrome; mesenchymal stem cells; obesity

(This special issue belongs to the Section Stem Cells)

The Molecular Research on Incretins and Diabetic Comorbidities

edited by

Michishige Terasaki

submission deadline 30 Aug 2024 | Viewed by 247 | Submission Open

Keywords: GIP; GLP-1; differentiation; atherosclerosis; intestine; animal models; drug screening

(This special issue belongs to the Section Cellular Metabolism)

The Cell Biology of Heart Disease

edited by Rajeshwary Ghosh and

Samreen Sadaf

submission deadline 30 Aug 2024 | Viewed by 220 | Submission Open

Keywords: cardiomyopathy; endothelial dysfunction; cellular senescence; fibrosis; myocardial infarction; inflammation; mitochondrial dysfunction; CAD; arrhythmia; heart failure

(This special issue belongs to the Section Cells of the Cardiovascular System)

Ion Channels in Pain: Mechanisms and Therapeutics

edited by Hongwei Yu, Michelino Puopolo and Seung Min Shin

submission deadline 30 Aug 2024 | Viewed by 177 | Submission Open

Keywords: chronic pain; sensory neurons; ion channels; pain mechanisms; pain therapeutics

(This special issue belongs to the Section Cells of the Nervous System)

Extracellular Vesicles as Biomarkers for Human Disease

edited by

Riccardo Di Santo

submission deadline 30 Aug 2024 | Viewed by 155 | Submission Open

Keywords: extracellular vesicles; exosomes; biomarkers; human diseases; diagnostic applications; prognostic indicators; EV subtypes; isolation techniques

(This special issue belongs to the Section Intracellular and Plasma Membranes)

Cell Death Mechanisms and Therapeutic Opportunities in Glioblastoma

edited by

Swapan K. Ray

submission deadline 31 Aug 2024 | 18 articles | Viewed by 36131 | Submission Open

Keywords: apoptosis; autophagy; cell death mechanisms; cell signaling; glioblastoma; therapeutic opportunities

(This special issue belongs to the Section Cells of the Nervous System)

CRISPR-Based Genome Editing in Translational Research—Second Edition

edited by Jifeng Zhang,

Dongshan Yang

and

Jie Xu

submission deadline 31 Aug 2024 | 7 articles | Viewed by 13234 | Submission Open

(This special issue belongs to the Section Cell and Gene Therapy)

The Therapeutic Role of Extracellular Vesicles in COVID-19: Therapeutic and Preventive Mechanism

edited by

Jisook Moon

submission deadline 31 Aug 2024 | 3 articles | Viewed by 10511 | Submission Open

Keywords: extracellular vesicles; severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease 2019 (COVID-19); EV-associated COVID-19 pathogenesis; therapeutic intervention; treatment

(This special issue belongs to the Section Cell Microenvironment)

Novel Insights into Molecular Mechanisms and Therapy of Asthma

edited by

Marco Caminati

submission deadline 31 Aug 2024 | 4 articles | Viewed by 9136 | Submission Open

(This special issue belongs to the Section Cellular Pathology)

The Applications of Flow Cytometry: Advances, Challenges, and Trends

edited by

David R. Kaplan

submission deadline 31 Aug 2024 | 2 articles | Viewed by 7688 | Submission Open

Keywords: flow cytometry; single cell; cell function; T-cell subset

(This special issue belongs to the Section Cell Methods)

The Emerging Role of Astrocytes in Health and Neurological Diseases

edited by

Italia Di Liegro

submission deadline 31 Aug 2024 | 4 articles | Viewed by 6874 | Submission Open

Keywords: astrocyte network; gliotransmitters; astrocytes in learning and memory; astrocytes and the blood– brain barrier; astrocyte pathologies

(This special issue belongs to the Section Cells of the Nervous System)

Tuberculosis: From Pathogenesis to Targeted Therapies

edited by

Christoph Hölscher

submission deadline 31 Aug 2024 | 3 articles | Viewed by 6309 | Submission Open

Keywords: tuberculosis; therapy; granuloma; antibiotics; host-directed

(This special issue belongs to the Section Cellular Pathology)

The Ubiquitin–Proteasome System (UPS): Signaling Processes and Targeted Protein Degradation

edited by

Bernat Crosas

submission deadline 31 Aug 2024 | 2 articles | Viewed by 5252 | Submission Open

Keywords: ubiquitin– proteasome system; ubiquitin ligases; targeted protein degradation; bispecific chimeras; novel chimera approaches

(This special issue belongs to the Section Cell Signaling)

The Pivotal Role of Tumor Stem Cells in Glioblastoma

edited by

Paola Palumbo

and Silvano J. Santini

submission deadline 31 Aug 2024 | 3 articles | Viewed by 3909 | Submission Open

Keywords: glioblastoma stem cells; resistance; cancer therapy; signaling pathways; tumor microenvironment

(This special issue belongs to the Section Stem Cells)

Gene Therapy for Rare Diseases

edited by

Cord Brakebusch

submission deadline 31 Aug 2024 | 3 articles | Viewed by 3444 | Submission Open

Keywords: gene therapy; gene editing; rare diseases; CRISPR; viral vectors; base editing; prime editing

(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)

State of the Art in Stem Cell Culture for Regenerative Medicine

edited by

Franca Di Meglio

Daria Nurzynska

and

Clotilde Castaldo

submission deadline 31 Aug 2024 | 2 articles | Viewed by 2982 | Submission Open

Keywords: stem cells; cell culture techniques; regenerative medicine; tissue engineering

(This special issue belongs to the Section Stem Cells)

New Strategies in Therapeutic Targets of Epilepsy

edited by Cameron S. Metcalf

submission deadline 31 Aug 2024 | 2 articles | Viewed by 2907 | Submission Open

Keywords: drug development; animal models; epilepsy; seizure; rare epilepsy; traumatic brain injury; epileptogenesis; disease modification; drug discovery

Oral Diseases: Biological and Molecular Pathogenesis

edited by

Hiromasa Hasegawa

submission deadline 31 Aug 2024 | 2 articles | Viewed by 2815 | Submission Open

Keywords: pathogenesis; immunohistochemical and molecular alteration; oral diseases

(This special issue belongs to the Section Cellular Pathology)

Molecular and Cellular Mechanisms of Cancers: Glioblastoma III

edited by

Javier S. Castresana

submission deadline 31 Aug 2024 | 2 articles | Viewed by 2219 | Submission Open

Keywords: glioblastoma genetics and epigenetics; molecular and cellular heterogeneity of glioblastoma; glioblastoma chemoresistance; glioblastoma migration; invasion and angiogenesis; glioblastoma liquid biopsy; glioblastoma targeted therapy; brain tumor stem cells; epithelial-to-mesenchymal transition in glioblastoma

(This special issue belongs to the Section Cellular Pathology)

Cell Adhesion/Migration in Tumor Metastasis

edited by

Daniel Bouvard

submission deadline 31 Aug 2024 | 1 articles | Viewed by 2073 | Submission Open

Keywords: cell adhesion; invasion; migration; extracellular matrix

(This special issue belongs to the Section Cell Motility and Adhesion)

Identifying Molecular or Cellular Level Pathomechanisms for Possible Therapeutic/Neuroprotective Interventions in Traumatic Brain Injury

edited by Krisztina Amrein and

Endre Czeiter

submission deadline 31 Aug 2024 | 1 articles | Viewed by 1832 | Submission Open

Keywords: traumatic brain injury; head injury; clinical study; experimental model; neuroprotective intervention; therapy; pathomechanism; molecular; cellular

(This special issue belongs to the Section Cellular Pathology)

Mechanisms of Respiratory Diseases

edited by

Bernhard Ryffel

and

David Rios-Covián

submission deadline 31 Aug 2024 | 1 articles | Viewed by 1776 | Submission Open

Keywords: cell death/stress; DNA/RNA sensor; cGAS/STING; inflammasome; microbiome; FMT or transfer of bacteria; metabolite; viral infection; emphysema; progressive fibrosis; innate immune response; defined inhibitors

(This special issue belongs to the Section Cellular Pathology)

Advances and Breakthroughs in Stem Cell Research

edited by

Alexander E. Kalyuzhny

and

Hemant Kumar Mishra

submission deadline 31 Aug 2024 | 1 articles | Viewed by 1638 | Submission Open

Keywords: stem cell; induced pluripotent stem cell; iPSC; hematopoietic stem cell

(This special issue belongs to the Section Stem Cells)

Apoptosis in Cancers

edited by

Inna N. Lavrik

submission deadline 31 Aug 2024 | 1 articles | Viewed by 1498 | Submission Open

Keywords: apoptosis; cancer; resistance; caspase; bcl-2; p53; death receptor; small molecules; pharmacological targeting

(This special issue belongs to the Section Cell Proliferation and Division)

Cellular and Clinical Mechanisms of Obesity and Diabetes and Their Complications

edited by

Eirini Kostopoulou

and

María Güemes

submission deadline 31 Aug 2024 | 1 articles | Viewed by 1448 | Submission Open

Keywords: obesity; type 1 diabetes; type 2 diabetes; metabolic disorders; complications; signaling pathways; pathophysiology; insulin; β -cell

(This special issue belongs to the Section Cellular Pathology)

Molecular Mechanisms and Clinical Treatments of Neurofibromatosis Type 1 Related Tumors

edited by

Andrea Rasola

and Federica Chiara

submission deadline 31 Aug 2024 | 1 articles | Viewed by 1000 | Submission Open

Keywords: neurofibromatosis type 1; rare tumors; genetic syndrome; plexiform neurofibroma; malignant peripheral nerve sheath tumor; tumor suppressor; Ras signalling; tumor microenvironment; anti-neoplastic therapy; neoplastic transformation

(This special issue belongs to the Section Cells of the Nervous System)

Antiphospholipid Syndrome: Molecular Mechanisms and Novel Therapies

edited by

Antonella Capozzi

and Simona Truglia

submission deadline 31 Aug 2024 | Viewed by 348 | Submission Open

Keywords: antiphospholipid syndrome; pathophysiology; management; treatment; antiphospholipid antibodies; molecular mechanisms; new biomarkers; diagnostic tests

(This special issue belongs to the Section Cellular Pathology)

Extracellular Vesicles in Tissue Repair and Regeneration

edited by

Mujib Ullah

submission deadline 31 Aug 2024 | Viewed by 296 | Submission Open

Keywords: stem cells; extracellular vesicles; exosomes; regeneration; tissue repair; cell signaling

(This special issue belongs to the Section Tissues and Organs)

Stem Cell Therapy for Autoimmune Diseases—Second Edition

edited by

Györgyi Műzes

and

Ferenc Sipos

submission deadline 31 Aug 2024 | Viewed by 243 | Submission Open

Keywords: autoimmune disease; stem cell therapy; hematopoietic stem cells; mesenchymal stem cells; MSC-derived secretome

Biomarkers for Therapeutic Advances in Breast Cancer

edited by

Nicola Fusco

Umberto Malapelle

and

Cristian Scatena

submission deadline 31 Aug 2024 | Viewed by 229 | Submission Open

Keywords: breast cancer; biomarkers; therapeutic strategies; targeted therapy; breast cancer management

(This special issue belongs to the Section Cellular Pathology)

Extracellular Vesicles-Related Cellular Events in Neuronal Biology: Regulated Cell Death, Autophagy, Unfolded Protein Response, and Stress-Related Pathways

edited by

Theologos Michaelidis

submission deadline 31 Aug 2024 | Viewed by 217 | Submission Open

Keywords: extracellular vesicles; exosomes; regulated (or programmed) cell death; autophagy; homeostasis; stress; unfolded protein response (UPR) signaling pathways; endoplasmic reticulum (ER) stress; protein quality control (PQC); mitochondria; neuron; neurogenesis; neurodegeneration; brain

(This special issue belongs to the Section Autophagy)

Human Inborn Errors of Immunity

edited by

Jacques Zimmer

submission deadline 31 Aug 2024 | Viewed by 213 | Submission Open

Keywords: inborn errors of immunity (IEI); primary immune deficiencies (PID); human; immune cells; susceptibility to infections; pathogens; autoimmunity; autoinflammation; allergy; malignancies; gene therapy; cellular therapy; hematopoietic stem cell transplantation (HSCT); pharmacotherapy

(This special issue belongs to the Section Cellular Immunology)

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