Special Issues

Cells publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Phosphodiesterases (PDEs): Therapeutic Targets in Human Health and Disease
edited by , , Michy P. Kelly and Leila Gobejishvili
submission deadline 31 Jul 2024 | 2 articles | Viewed by 2597 | Submission Open
Keywords: cyclic nucleotide phosphodiesterase; PDE; cAMP; cGMP; signal transduction
Protein Misfolding Diseases: From Experimental Approaches to Therapeutic Opportunities submission deadline 31 Jul 2024 | 1 articles | Viewed by 2452 | Submission Open
Keywords: protein aggregation; amyloid; neurodegenerative diseases; cancer; diabetes
(This special issue belongs to the Section Cellular Pathology)
Therapeutic Potentials of Adipose-Derived Stem Cells
edited by
submission deadline 31 Jul 2024 | 2 articles | Viewed by 2437 | Submission Open
Keywords: adipose stem cells; tissue regeneration; clinical applications
(This special issue belongs to the Section Tissues and Organs)
Cellular Regulation of Pathological Proteins in Neurodegenerative Disease
edited by Sonia Sirisi
submission deadline 31 Jul 2024 | 1 articles | Viewed by 2297 | Submission Open
Keywords: protein aggregates; neurodegeneration; neurodegenerative diseases; regulation pathways; misfolded proteins; toxic proteins; homeostasis; autophagy
(This special issue belongs to the Section Cells of the Nervous System)
Immunopharmacology: Current Applications and Future Perspectives submission deadline 31 Jul 2024 | 1 articles | Viewed by 2082 | Submission Open
Keywords: drug discovery; immunotherapy; immunopharmacology; human diseases
(This special issue belongs to the Section Cellular Immunology)
Glutamatergic Transmission in Brain Development and Disease
edited by Miranda Nicole Reed, Subhrajit Bhattacharya and Vishnu Suppiramaniam
submission deadline 31 Jul 2024 | 1 articles | Viewed by 1792 | Submission Open
(This special issue belongs to the Section Tissues and Organs)
Human Placenta and Trophoblast Cells in Pregnancy Development
edited by
submission deadline 31 Jul 2024 | 1 articles | Viewed by 1397 | Submission Open
Keywords: placenta; trophoblast; pregnancy
(This special issue belongs to the Section Reproductive Cells and Development)
Nonalcoholic Fatty Liver Disease: From Mechanisms to Therapeutics
edited by and Alessandra Scamporrino
submission deadline 31 Jul 2024 | 1 articles | Viewed by 1317 | Submission Open
Keywords: NAFL; NASH; cirrhosis; molecular mechanisms; liver; gut; metabolic tissues
(This special issue belongs to the Section Cellular Metabolism)
Kinase Signaling and Kinase-Targeted Therapies on Cancer: Advances, Challenges, and Future Directions—Second Edition
edited by
submission deadline 31 Jul 2024 | Viewed by 608 | Submission Open
Keywords: cancer; oncogene; kinase inhibitors; tumor drug resistance; signal transduction; survival; cell reprogramming; target therapy; cancer heterogeneity; biomarkers
The Role of PPARs in Disease - Volume III submission deadline 31 Jul 2024 | 1 articles | Viewed by 565 | Submission Open
Keywords: PPAR; immune function; liver; adipose tissue; cardiovascular system; muscle; neurological and psychiatric diseases; cancer; transcriptional regulation; ligands; agonists/antagonists
Photodynamic Biology
edited by
submission deadline 31 Jul 2024 | Viewed by 487 | Submission Open
Keywords: photodynamic action; autophagy; singlet oxygen; cellular function; functional proteins; photosensitizers; phototoxicity; bioluminescent proteins as light sources
(This special issue belongs to the Section Cellular Biophysics)
Cellular Homeostasis and Quality Control submission deadline 31 Jul 2024 | Viewed by 474 | Submission Open
Keywords: cellular homeostasis; protein trafficking and quality control; mitochondrial dysfunction; lysosomal storage disorders; neurodegeration; aging
(This special issue belongs to the Section Cell Microenvironment)
New Developments in Rheumatoid Arthritis
edited by and Alf Kastbom
submission deadline 31 Jul 2024 | Viewed by 398 | Submission Open
Keywords: rheumatoid arthritis; autoimmunity; metabolism; risk factors; treatment
(This special issue belongs to the Section Cellular Immunology)
Novel Insights into the Biofilms
edited by and Pierre Cornelis
submission deadline 31 Jul 2024 | Viewed by 224 | Submission Open
Keywords: biofilms maturation; biofilm matrix; regulation; dispersion; eradication
Pulmonary Hypertension: From Molecular and Cellular Mechanisms to Therapeutic Opportunities
edited by
submission deadline 31 Jul 2024 | Viewed by 161 | Submission Open
Keywords: pulmonary hypertension; molecular mechanism; cellular responses; signaling mechanisms; novel diagnosis and treatments
(This special issue belongs to the Section Cells of the Cardiovascular System)
Molecular Genetics of Eye Development and Myopia
edited by Joanna Swierkowska, and
submission deadline 31 Jul 2024 | Viewed by 150 | Submission Open
Keywords: myopia; high myopia; refractive error; genetics of eye disorders; candidate genes; animal models; epigenetics; transcriptomics; retina; cell lines
(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)
Targeted Therapy for Metastatic Cancer
edited by Ila Pant
submission deadline 31 Jul 2024 | Viewed by 132 | Submission Open
Keywords: immunotherapy; monoclonal antibodies; DNA- or RNA-based targeted therapy; small molecule inhibitors; targeted nano-delivery systems; resistance to targeted therapies
Advanced Research on Retina: Recent Development of Genome Editing Strategies Aimed at Treating Inherited Retinal Diseases
edited by Lijin Dong
submission deadline 31 Jul 2024 | Viewed by 127 | Submission Open
Keywords: retina; RPE; neurodegeneration; retina neurodegeneration; retinitis pigmentosa; genome editing; CRISPR; DNA double strand break; DNA repair; homologous recombination; indel
(This special issue belongs to the Section Cell and Gene Therapy)
Novel Insights into Molecular Mechanisms and Therapy of Soft Tissue Sarcomas submission deadline 31 Jul 2024 | Viewed by 81 | Submission Open
Keywords: soft tissue sarcoma; molecular genetics; epigenetics  ; gene expression  ; ncRNA  ; post-transcriptional regulations  ; post-translational modifications  ; targeted therapy  ; drug resistance  ; molecular biomarkers
(This special issue belongs to the Section Tissues and Organs)
Control of Gene Expression by Co-transcriptional Processes in Cell Homeostasis and Cell Fate Specification: Second Edition
edited by
submission deadline 31 Jul 2024 | Viewed by 65 | Submission Open
Keywords: gene transcription; transcription elongation; RNA processing; RNA modification; RNA transport; lncRNA; histone modification; biomolecular condensates; diseases associated with dysregulation of gene regulation
(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)
The Involvement of T Cells and Their Cytokines in Scleroderma (Systemic Sclerosis)—Second Edition
edited by
submission deadline 31 Jul 2024 | Viewed by 48 | Submission Open
Keywords: cancer; oncogene; kinase inhibitors; tumor drug resistance; signal transduction; survival; cell reprogramming; target therapy; cancer heterogeneity; biomarkers
Alzheimer's Disease: Molecular Mechanisms and Novel Treatment Strategies submission deadline 1 Aug 2024 | 6 articles | Viewed by 14481 | Submission Open
Keywords: Alzheimer's disease; neurodegeneration; risk factors; therapy
(This special issue belongs to the Section Cells of the Nervous System)
Primary Cilia in Health and Diseases
edited by
submission deadline 1 Aug 2024 | 2 articles | Viewed by 4850 | Submission Open
Keywords: primary cilia; ciliogenesis; ciliopathy; development; signaling; sensory system; disease; screening
(This special issue belongs to the Section Cell Motility and Adhesion)
Signaling Pathways In Development and Ageing
edited by
submission deadline 1 Aug 2024 | 2 articles | Viewed by 4436 | Submission Open
Keywords: autism; intellectual disability; developmental delays; schizophrenia; Alzheimer’ s disease; neurodegeneration; neuroprotection; cellular mechanisms
(This special issue belongs to the Section Cellular Aging)
Retinal Pigment Epithelial Cells in Age-Related Macular Degeneration
edited by Sujoy Bhattacharya
submission deadline 1 Aug 2024 | Viewed by 180 | Submission Open
Keywords: atrophic age-related macular degeneration; iPSC-derived RPE; animal models
(This special issue belongs to the Section Cellular Aging)
Pathophysiology of Signal Transduction in Cardiovascular and Pulmonary Disease II
edited by and
submission deadline 1 Aug 2024 | Viewed by 140 | Submission Open
Keywords: cardiac arrhythmia; atrium; ventricle; pulmonary; vascular; signal transduction
(This special issue belongs to the Section Cellular Pathology)
Advances in Antithrombotic Research: From Pharmacological Mechanisms to Innovative Approaches submission deadline 10 Aug 2024 | 2 articles | Viewed by 16179 | Submission Open
Keywords: atherothrombosis; thromboembolic cardiac embolism; unusual site of thrombosis; venous thromboembolism; thrombophilia; acute antithrombotic treatment; chronic long-term antithrombotic treatment; antithrombotics; antiplatelets; anticoagulants; warfarin; heparins; low molecular weight heparins; direct oral anticoagulants; aspirin; ticagrelor; clopidogrel; statins; PCSK9 inhibitors; immunomodulant therapy; evolocumab; alirocumab; eltrombopag
Cell and Immune Therapeutics for Gliomas
edited by and
submission deadline 10 Aug 2024 | 1 articles | Viewed by 1541 | Submission Open
Keywords: immune modulation; T-cell activation; tumour-associated macrophages; tumour microenvironment; stem cells
(This special issue belongs to the Section Cell Microenvironment)
The Role of Inflammation in Atherosclerosis and Coronary Artery Disease—2nd Edition
edited by
submission deadline 10 Aug 2024 | Viewed by 108 | Submission Open
Keywords: atherosclerosis; coronary artery disease; inflammation; cytokines; white blood cells; monocyte; macrophage; adhesion molecule; chemokines; thrombosis; diabetes
(This special issue belongs to the Section Cells of the Cardiovascular System)
New Insights into Adipose-Derived Stem Cells (ADSCs)
edited by , and William D’Angelo
submission deadline 15 Aug 2024 | 2 articles | Viewed by 4075 | Submission Open
Keywords: adipose-derived stem cells; immunomodulation; exosomes; cell therapy; clinical translation
(This special issue belongs to the Section Stem Cells)
Non-coding RNAs: Multiple Players in Human Diseases
edited by
submission deadline 15 Aug 2024 | 1 articles | Viewed by 1807 | Submission Open
Keywords: non-coding RNA; human disease; epigenetic marker; therapy; pathogenesis; transcriptome
(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)
Cellular and Molecular Mechanisms of Multiple Drug Resistance (MDR) submission deadline 15 Aug 2024 | 1 articles | Viewed by 1625 | Submission Open
Keywords: multidrug resistance (MDR); detoxification; cellular drug modification/elimination; ER stress; cell death; DNA repair; epigenetics regulation
Autophagosome Formation
edited by Yan Zhen and Ikuko Koyama-Honda
submission deadline 15 Aug 2024 | Viewed by 155 | Submission Open
Keywords: ATG2; ATG9; autophagosome; endosome; membrane contact site; omegasome; phagophore; lipid channel; lipid scramblase
(This special issue belongs to the Section Autophagy)
Novel Mechanisms of Gene Regulation in Cardiac Development and Congenital Heart Defects
edited by
submission deadline 15 Aug 2024 | Viewed by 118 | Submission Open
Keywords: long noncoding RNA; epigenetic regulation; whole-genome sequencing; cardiomyocyte signaling; cardiovascular development  ; congenital heart defects
(This special issue belongs to the Section Cells of the Cardiovascular System)
The Interplay of G-Protein-Coupled Receptor Signaling between Humans and Diseases
edited by Victor Garcia
submission deadline 15 Aug 2024 | Viewed by 78 | Submission Open
Keywords: G-proteins; G-protein-coupled receptors; G-protein-independent signaling; cAMP signals
Brain Tumors: From Neuropathology to Molecular Biology
edited by , Marialaura Del Basso De Caro and
submission deadline 20 Aug 2024 | Viewed by 243 | Submission Open
Keywords: brain tumor pathology; neuro-oncology; molecular biology; immunohistochemistry; histopathology
(This special issue belongs to the Section Cellular Pathology)
Molecular and Cellular Mechanisms on Plant Polyphenols submission deadline 20 Aug 2024 | Viewed by 192 | Submission Open
Keywords: natural polyphenols; cell homeostasis; anti-oxidant; anti-inflammatory; health effects
(This special issue belongs to the Section Plant, Algae and Fungi Cell Biology)
Kidney Disease Models, Cellular Mechanism and Potential Treatment
edited by
submission deadline 20 Aug 2024 | Viewed by 116 | Submission Open
Keywords: kidney disease; signaling pathways; therapy; biomarker; prevention
(This special issue belongs to the Section Tissues and Organs)
Molecular Mechanism of Bone Disease submission deadline 20 Aug 2024 | Viewed by 105 | Submission Open
Keywords: bone; mesenchymal stem cells; transcription factors; bone rare diseases; skeletal degenerative diseases
Regulation of Fibroblasts and Fibrosis in Cardiovascular Disease
edited by
submission deadline 20 Aug 2024 | Viewed by 84 | Submission Open
Keywords: fibrosis; fibroblasts; cardiovascular; inflammation; extracellular matrix; collagen
(This special issue belongs to the Section Cells of the Cardiovascular System)
Inflammation in Target Organs
edited by
submission deadline 29 Aug 2024 | 1 articles | Viewed by 1642 | Submission Open
Keywords: inflammation; fibrosis; cardio-renal; vascular; liver; brain
(This special issue belongs to the Section Cellular Immunology)
Fat Is a Matter? The Implication of Adipose Tissue in Cardiovascular Health and Disease
edited by
submission deadline 30 Aug 2024 | 3 articles | Viewed by 8560 | Submission Open
Keywords: adipose tissue; adipocyte; cardiovascular disease; metabolic disease; energy homeostasis
(This special issue belongs to the Section Cellular Metabolism)
Regulatory T Cells and Autoimmunity
edited by Fan Pan
submission deadline 30 Aug 2024 | 1 articles | Viewed by 1742 | Submission Open
Keywords: regulatory T cells; immune tolerance; Foxp3; autoimmune disease (AD); immunotherapy
(This special issue belongs to the Section Cellular Immunology)
Pluripotent Stem Cells: Current Applications and Future Directions
edited by
submission deadline 30 Aug 2024 | 1 articles | Viewed by 1066 | Submission Open
Keywords: induced pluripotent stem cells; organoids; reprogramming; differentiation; spheroids; cortical organoids; intestinal organoids; kidney organoids; cardiomyocytes; astrocytes; microglia; personalized medicine; drug screening; disease modeling
(This special issue belongs to the Section Stem Cells)
Focus on Redox Signaling submission deadline 30 Aug 2024 | Viewed by 268 | Submission Open
Keywords: redox signaling; oxidative stress; reactive oxygen species (ROS); reactive molecules; cellular signaling; human diseases
(This special issue belongs to the Section Cell Signaling)
The Molecular Research on Incretins and Diabetic Comorbidities submission deadline 30 Aug 2024 | Viewed by 205 | Submission Open
Keywords: GIP; GLP-1; differentiation; atherosclerosis; intestine; animal models; drug screening
(This special issue belongs to the Section Cellular Metabolism)
Multifaceted Roles of Mesenchymal Stem Cells in Health and Disease
edited by and Bartłomiej Łukaszuk
submission deadline 30 Aug 2024 | Viewed by 186 | Submission Open
Keywords: diabetes mellitus; dyslipidemia; insulin resistance; metabolic syndrome; mesenchymal stem cells; obesity
(This special issue belongs to the Section Stem Cells)
The Cell Biology of Heart Disease
edited by Rajeshwary Ghosh and
submission deadline 30 Aug 2024 | Viewed by 157 | Submission Open
Keywords: cardiomyopathy; endothelial dysfunction; cellular senescence; fibrosis; myocardial infarction; inflammation; mitochondrial dysfunction; CAD; arrhythmia; heart failure
(This special issue belongs to the Section Cells of the Cardiovascular System)
Ion Channels in Pain: Mechanisms and Therapeutics
edited by Hongwei Yu, Michelino Puopolo and Seung Min Shin
submission deadline 30 Aug 2024 | Viewed by 125 | Submission Open
Keywords: chronic pain; sensory neurons; ion channels; pain mechanisms; pain therapeutics
(This special issue belongs to the Section Cells of the Nervous System)
Extracellular Vesicles as Biomarkers for Human Disease
edited by
submission deadline 30 Aug 2024 | Viewed by 87 | Submission Open
Keywords: extracellular vesicles; exosomes; biomarkers; human diseases; diagnostic applications; prognostic indicators; EV subtypes; isolation techniques
(This special issue belongs to the Section Intracellular and Plasma Membranes)
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