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Cells publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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The Cell Biology of Heart Disease

edited by Rajeshwary Ghosh and

Samreen Sadaf

submission deadline 30 Jan 2025 | Viewed by 360 | Submission Open

Keywords: cardiomyopathy; endothelial dysfunction; cellular senescence; fibrosis; myocardial infarction; inflammation; mitochondrial dysfunction; CAD; arrhythmia; heart failure

(This special issue belongs to the Section Cells of the Cardiovascular System)

Signaling in Cancer Stem Cells

edited by Upasana Ray

submission deadline 30 Jan 2025 | Viewed by 282 | Submission Open

Keywords: cancer stem cells (CSCs); stem cells signaling pathways; cancer progression and metastasis; therapeutic resistance; targeting cancer stem cells signaling; cancer heterogeneity; targeted therapy for CSCs; identifying biomarkers for CSCs

(This special issue belongs to the Section Stem Cells)

Advances in Scanning Probe Microscopy in Cell Biology

edited by

Yuri M. Efremov

and

Petr V. Gorelkin

submission deadline 31 Jan 2025 | 13 articles | Viewed by 23606 | Submission Open

Roles and Mechanisms of Ubiquitin Ligases (E3) and Deubiquitinases (DUBs)

edited by

Minsoo Kim

, Tsunehiro Mizushima and Hideki Yashiroda

submission deadline 31 Jan 2025 | 9 articles | Viewed by 15505 | Submission Open

Keywords: E3 ubiquitin ligases; deubiquitinases; ubiquitin; ubiquitination; proteasome

(This special issue belongs to the Section Cell Signaling)

The Emerging Role of Astrocytes in Health and Neurological Diseases

edited by

Italia Di Liegro

submission deadline 31 Jan 2025 | 6 articles | Viewed by 12279 | Submission Open

Keywords: astrocyte network; gliotransmitters; astrocytes in learning and memory; astrocytes and the blood– brain barrier; astrocyte pathologies

(This special issue belongs to the Section Cells of the Nervous System)

Advanced Technology for Cellular Imaging

edited by Alessandro Grinzato,

Vittoria Raimondi

and

J. Bernard Heymann

submission deadline 31 Jan 2025 | 7 articles | Viewed by 11173 | Submission Open

Keywords: electron tomography; fluorescence microscopy; live cell imaging; multimodal imaging; super resolution microscopy; cell– cell interaction

(This special issue belongs to the Section Cell Methods)

Understanding Spinal Cord Injury and Repair: From Molecules to Neurocircuits and Multimodal Prostheses

edited by

Yang D. Teng

submission deadline 31 Jan 2025 | 7 articles | Viewed by 10691 | Submission Open

(This special issue belongs to the Section Cells of the Nervous System)

Organ and Tissue Fibrosis: Molecular Signals and Cellular Mechanisms

edited by

Zhuo Wang

submission deadline 31 Jan 2025 | 5 articles | Viewed by 10496 | Submission Open

Keywords: fibrosis; scarring; cytokine; myofibroblasts; extracellular matrix; growth factors; mesenchymal transition

(This special issue belongs to the Section Tissues and Organs)

Molecular Mechanisms of Cell Division and Chromosome Segregation: What Can Go Wrong?

edited by

Patrizio Dimitri

Giovanni Messina

and

Yuri Prozzillo

submission deadline 31 Jan 2025 | 4 articles | Viewed by 9362 | Submission Open

Keywords: mitosis; cell division; genetic instability; aneuploidy; lagging chromosomes; chrosomomes misalignment; mitotic checkpoint; microtubules attachment; kinetochores; microtubules dynamics

(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)

Microenvironmental Factors and Functional Modulation in Mesenchymal Stem Cells 2.0

edited by

Mohamed Mekhemar

and

Karim Mohamed Fawzy El-Sayed

submission deadline 31 Jan 2025 | 5 articles | Viewed by 6888 | Submission Open

Keywords: mesenchymal stem cells; inflammation; microenvironment; regeneration of mesenchymal stem cell receptors; stem cell differentiation

(This special issue belongs to the Section Stem Cells)

Molecular and Cellular Mechanisms of Cardiovascular and Metabolic Diseases

edited by

Prathapan Ayyappan

submission deadline 31 Jan 2025 | 4 articles | Viewed by 6586 | Submission Open

Keywords: mitochondrial dysfunction; endoplasmic reticulum (ER) stress; oxidative/nitrosative stress; diabetes; obesity; diet; atherosclerosis; hypertension; metabolomics; cell death; nutraceuticals/functional foods

(This special issue belongs to the Section Cells of the Cardiovascular System)

Cellular Mechanisms in Autoimmune Encephalitis: Biology and Potential Therapeutic Implications

edited by

Mar Petit-Pedrol

and Dominique Fernandes

submission deadline 31 Jan 2025 | 1 articles | Viewed by 4010 | Submission Open

Keywords: neuroimmunology; pathogenesis; diagnosis; neuroimmune disorders; autoimmune encephalitis

(This special issue belongs to the Section Cells of the Nervous System)

Mitochondria and Other Organelles in Neurodegenerative Diseases

edited by Tian Liu

submission deadline 31 Jan 2025 | 2 articles | Viewed by 3629 | Submission Open

Keywords: mitochondria dysfunction; ER stress; TDP-43 pathology; protein aggregation; tauopathy; neuroinflammation; neurodegeneration; neurodegenerative diseases; therapeutic approaches

(This special issue belongs to the Section Intracellular and Plasma Membranes)

New Trends and Advances in Diagnosis and Prognosis of Head and Neck Cancer from Carcinogenesis to Future Molecular Targeted Therapies: 2nd Edition

edited by

Piotr Cierpikowski

and

Julia Bar

submission deadline 31 Jan 2025 | 2 articles | Viewed by 2553 | Submission Open

Keywords: head and neck cancer; oral cancer; biomarker; prognosis; carcinogenesis; oral premalignant lesions; cancer stem cells; signaling pathways; molecular targeted therapy

(This special issue belongs to the Section Cellular Pathology)

Demystifying the Role of the Immune System in Modulating Pathogenic Fibrosis

edited by Gerlinde Wernig and

Cristabelle De Souza

submission deadline 31 Jan 2025 | 1 articles | Viewed by 2133 | Submission Open

Keywords: unifying fibrotic mechanisms; genetic markers of disease; innate immunity; drug discovery

(This special issue belongs to the Section Cellular Pathology)

Cellular and Molecular Events in Intervertebral Disc Development, Homeostasis and Disease

edited by

Graciosa Teixeira

submission deadline 31 Jan 2025 | 1 articles | Viewed by 1208 | Submission Open

Keywords: disc development; healthy intervertebral disc; IVD

Ion Channel Involvement in Neurological and Neuromuscular Disorders

edited by

Elena Conte

and

Concetta Altamura

submission deadline 31 Jan 2025 | 1 articles | Viewed by 1082 | Submission Open

Keywords: ion channels; neurological diseases; neuromuscular diseases; personalized therapy

(This special issue belongs to the Section Cells of the Nervous System)

Research on the Amyloid in Alzheimer’s Disease

edited by Archna Sharma

submission deadline 31 Jan 2025 | 1 articles | Viewed by 1014 | Submission Open

Keywords: amyloid; Alzheimer’ s disease; amyloid biomarkers; brain network; anti-amyloid immunotherapy; inducible pluripotent stem cells; neuron and non-neuron differentiation; brain organoids; amyloidopathy animal models

(This special issue belongs to the Section Cellular Aging)

Cilia-Based New Discoveries: Ciliogenesis, Function, and Human Diseases

edited by

Lisbeth Birk Møller

submission deadline 31 Jan 2025 | 1 articles | Viewed by 547 | Submission Open

Keywords: primary cilium; human disease; cell signaling; mTOR; Hedgehog; WNT; PDGFRalpha

Pathogenesis of Diabetic Kidney Disease

edited by Jia Fu

submission deadline 31 Jan 2025 | Viewed by 256 | Submission Open

Keywords: diabetic kidney disease (DKD); molecular mechanism; oxidative stress; chronic kidney disease; pathogenesis; diagnostic and therapeutic strategies; inflammation; metabolic dysfunction

(This special issue belongs to the Section Cellular Pathology)

Impact of Platelet Defects on Pathophysiological Processes II

edited by

Barbara Zieger

and

Kerstin Jurk

submission deadline 31 Jan 2025 | Viewed by 234 | Submission Open

Keywords: platelet physiology; platelet pathophysiology; inherited platelet defects; signaling; bleeding; sepsis; acquired platelet disorder; developmental pathogenesis

(This special issue belongs to the Section Cellular Pathology)

The Interplay between the Immune and Central Nervous Systems in Health and Disease: Current Insights and Future Directions

edited by

Chiara Burgaletto

submission deadline 31 Jan 2025 | Viewed by 229 | Submission Open

Keywords: astrocytes; immunotherapy; inflammatory response; innate and adaptive immunity; microglia; neuroinflammation; neurological diseases; psychiatric disorders; therapeutic avenues

(This special issue belongs to the Section Cellular Immunology)

Advances in Muscle Research in Health and Disease—2nd Edition

edited by

Wan Lee

submission deadline 31 Jan 2025 | Viewed by 220 | Submission Open

Keywords: skeletal muscle; cardiac muscle; smooth muscle; myocyte; vascular smooth muscle cell; stem cell; development; homeostasis; regeneration; biomarker; therapeutic target

Retinal Pigment Epithelium in Degenerative Retinal Diseases

edited by Jian Liu and Shintaro Horie

submission deadline 31 Jan 2025 | Viewed by 209 | Submission Open

Keywords: RPE; degenerative retinal diseases; macular degeneration; diabetic retinopathy; glaucoma; photoreceptor; vascular endothelium; microglia; macrophage; inflammation; oxidative stress; autophagy; mitochondria; lipid metabolism; senescence; neuropeptide; therapeutics; biomarkers

(This special issue belongs to the Section Cellular Pathology)

The Diverse Roles of DNA Methylation and Hydroxymethylation in Embryonic Development

edited by

Douglas M. Ruden

submission deadline 31 Jan 2025 | Viewed by 200 | Submission Open

Keywords: DNA methylation; DNA hydroxymethylation; mouse embryonic development; human embryonic development; Tet; Dnmt

Neuroinflammation in Brain Health and Diseases

edited by Debashis Dutta and Nemil Bhatt

submission deadline 31 Jan 2025 | Viewed by 190 | Submission Open

Keywords: neuroinflammation; gliosis; inflammasome; neurodegeneration; neurotherapeutics

Molecular Research of Cardiomyopathy

edited by

Luigi Sansone

and

Manuel Belli

submission deadline 31 Jan 2025 | Viewed by 186 | Submission Open

Keywords: cardiomyopathy; heart failure; hypertrophic cardiomyopathy; cellular and molecular rehabilitation

The Role Glial Cells in Neurodegenerative Disorders

edited by

Susmita Sil

submission deadline 31 Jan 2025 | Viewed by 175 | Submission Open

Keywords: neurodegeneration; neuroinflammation; microglia; astrocytes; neuron; extracellular vesicles; therapeutics

Regulation of Cell Division

edited by Katie Shannon

submission deadline 31 Jan 2025 | Viewed by 164 | Submission Open

Keywords: mitosis; kinetochore; chromosome segregation; actomyosin ring; cytokinesis; septation; mitotic exit network; spindle assembly checkpoint

(This special issue belongs to the Section Cell Proliferation and Division)

New Targets and Therapeutic Approaches Based on Molecular Mechanisms in Tumorigenesis and Cancer Metastasis

edited by

Francesc Mitjans

submission deadline 31 Jan 2025 | Viewed by 152 | Submission Open

Keywords: metastasis; cancer; therapy; precision medicine; cancer stem cells; immuno-oncology; tumor microenvironment; antibody

(This special issue belongs to the Section Cell Microenvironment)

Natural Killer (NK) Cells in Immunity: Limitations and Potential

edited by Rehan Mujeeb Faridi

submission deadline 31 Jan 2025 | Viewed by 135 | Submission Open

Keywords: natural killer cells; adaptive NK cells; infection

(This special issue belongs to the Section Cellular Immunology)

The Role of Stem Cells and Circadian Clock in Cancer Immunotherapy

edited by Yool Lee

submission deadline 31 Jan 2025 | Viewed by 94 | Submission Open

Keywords: circadian clock; circadian disruption; neural stem cells; cancer stem cells; tumor– immune microenvironment; cancer chronotherapy

(This special issue belongs to the Section Stem Cells)

Regulatory T Cells and Autoimmunity

edited by Fan Pan

submission deadline 10 Feb 2025 | 2 articles | Viewed by 4163 | Submission Open

Keywords: regulatory T cells; immune tolerance; Foxp3; autoimmune disease (AD); immunotherapy

(This special issue belongs to the Section Cellular Immunology)

Novel Biomarkers in Eye Diseases

edited by

Alessandra Micera

submission deadline 10 Feb 2025 | Viewed by 73 | Submission Open

Keywords: biomarkers; tears; ocular surface; retina; ocular fluids; inflammation; neuromodulation; parainflammation; omics; lab-on-chip

(This special issue belongs to the Section Cellular Pathology)

Novel Insights into Molecular Mechanisms and Therapy of Asthma

edited by

Marco Caminati

submission deadline 15 Feb 2025 | 4 articles | Viewed by 15030 | Submission Open

(This special issue belongs to the Section Cellular Pathology)

Stem Cell, Differentiation, Regeneration and Diseases

edited by

Guoying Yu

, Guoqiang Sun and

Jiancheng Liu

submission deadline 15 Feb 2025 | 8 articles | Viewed by 14055 | Submission Open

Keywords: stem cell; development; differentiation; tissue regeneration; organoid; disease modeling; stem cell therapy; cancer

(This special issue belongs to the Section Stem Cells)

Drosophila Models in Autophagy and Aging

edited by

Athanassios D. Velentzas

Dimitrios J. Stravopodis

and Panagiotis D. Velentzas

submission deadline 15 Feb 2025 | 3 articles | Viewed by 4910 | Submission Open

Keywords: autophagy; apoptosis; brain– gut axis; brainopathies; development; Drosophila model of human diseases; microbiome; mitophagy; necrosis; neurodegenerative diseases; proteostasis; signaling; ubiquitin– proteasome system

(This special issue belongs to the Section Autophagy)

Research on Proteomics and Its Applications in Disease

edited by

Claudia Landi

submission deadline 15 Feb 2025 | 1 articles | Viewed by 2226 | Submission Open

Keywords: bottom-up proteomics; top-down proteomics; spatial proteomics; bioinformatics; human diseases; cancer; viral infections; bacterial infections; rare pathologies

(This special issue belongs to the Section Cell Methods)

Large-Scale Multi-Omic Approaches and Atlas-Based Profiling for Cellular, Molecular, and Functional Specificity, Heterogeneity, and Diversity in the Endocannabinoid System

edited by

Jun Aoki

and

Masako Isokawa

submission deadline 15 Feb 2025 | 1 articles | Viewed by 1554 | Submission Open

Keywords: lipidomics; proteomics; transcriptomics; cluster analysis; massive parallel screening; molecular markers; brain circuits; development; neural plasticity; synapse; appetite and feeding behavior; addiction; pain; epilepsy; neurological disorders

(This special issue belongs to the Section Cells of the Nervous System)

Molecular Mechanisms and Pathophysiology of Diabetic Retinopathy

edited by

Siddharth Sunilkumar

, Stephanie L. Grillo and Sandeep M. Subrahmanian

submission deadline 15 Feb 2025 | Viewed by 239 | Submission Open

Keywords: diabetic retinopathy; retina; retinal neurodegeneration; diabetic macular edema; pathophysiology of diabetic retinopathy; proliferative and non-proliferative diabetic retinopathy; molecular mediators of diabetic retinopathy; cell-based therapies for diabetic retinopathy

(This special issue belongs to the Section Cellular Pathology)

Epigenetic Mechanisms of Tumorigenesis

edited by

Hengbin Wang

submission deadline 15 Feb 2025 | Viewed by 160 | Submission Open

Keywords: epigenetics; tumorigenesis; gene expression; cell identity; precise medicine

Mechanism of Cell Signaling during Eye Development and Diseases

edited by

Mehrnoosh Saghizadeh Ghiam

and

Vivien Coulson-Thomas

submission deadline 20 Feb 2025 | 9 articles | Viewed by 16286 | Submission Open

Keywords: cell signaling; ocular; eye disorders; Wnt signaling; TGF-β

(This special issue belongs to the Section Cell Signaling)

Unlocking the Secrets Behind Drug Resistance at the Cellular Level

edited by

Sara Ricardo

and

Cristina Pinto Ribeiro Xavier

submission deadline 20 Feb 2025 | 2 articles | Viewed by 3363 | Submission Open

Keywords: molecular mechanisms; effective treatments; drug tests; bacterial resistance; chemoresistance

(This special issue belongs to the Section Cellular Immunology)

Advances in DNA Repair Disorders Research: Molecular Mechanisms, Novel Therapies and Implications for Understanding Aging, Neurological Dysfunction and Cancer Progression

edited by Manuela Lanzafame

submission deadline 20 Feb 2025 | 2 articles | Viewed by 2329 | Submission Open

Keywords: DNA repair diseases; molecular mechanism; signaling pathway; therapies; aging; cancer; neurological dysfunction

(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)

Control of Gene Expression by Co-transcriptional Processes in Cell Homeostasis and Cell Fate Specification: Second Edition

edited by

Yutaka Hirose

submission deadline 20 Feb 2025 | 1 articles | Viewed by 1030 | Submission Open

Keywords: gene transcription; transcription elongation; RNA processing; RNA modification; RNA transport; lncRNA; histone modification; biomolecular condensates; diseases associated with dysregulation of gene regulation

(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)

Cell Therapeutics for Corneal Diseases

edited by

Dimitrios Karamichos

submission deadline 20 Feb 2025 | 1 articles | Viewed by 794 | Submission Open

Keywords: cell therapies; corneal diseases; drug development; tissue engineering; stem cells; regeneration; tissue repair

Gene and Cellular Signaling Related to Muscle

edited by

Khurshid Ahmad

submission deadline 20 Feb 2025 | Viewed by 172 | Submission Open

Keywords: skeletal muscle; molecular mechanism; muscle atrophy; therapeutics; metabolic signals; satellite cells

Signaling Pathways Involved in Tumor Microenvironment and Tumor Adaptation to Stresses

edited by Nianli Sang

submission deadline 20 Feb 2025 | Viewed by 167 | Submission Open

Keywords: microenvironment; metabolic stress; hypoxia; chemoresistance; radiation resistance; apoptosis; metabolic reprogramming; metastasis

Molecular Mechanisms of Exercise on Cardiac and Skeletal Muscle Function

edited by Kisuk Min

submission deadline 20 Feb 2025 | Viewed by 124 | Submission Open

Keywords: exercise physiology; cardiac muscle function; skeletal muscle function; molecular mechanisms; mitochondrial biogenesis; oxidative stress; muscle hypertrophy; inflammatory responses; cellular signaling pathways; metabolic adaptation

(This special issue belongs to the Section Cellular Pathology)

Advances in Immunotherapy for Non-Small-Cell Lung Cancer

edited by

Raheleh Roudi

submission deadline 20 Feb 2025 | Viewed by 124 | Submission Open

Keywords: non-small cell lung cancer; immunotherapy; immune checkpoint inhibitors; PD-1; PD-L1; pembrolizumab; nivolumab; atezolizumab; CTLA4

(This special issue belongs to the Section Cellular Immunology)

Displaying special issue 151-200 on page 4 of 10.

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