Special Issues

Cells publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Cell Death Mechanisms and Therapeutic Opportunities in Glioblastoma
edited by
submission deadline 31 Aug 2024 | 16 articles | Viewed by 28769 | Submission Open
Keywords: apoptosis; autophagy; cell death mechanisms; cell signaling; glioblastoma; therapeutic opportunities
(This special issue belongs to the Section Cells of the Nervous System)
Proteomic Applications in Ageing and Neurodegenerative Conditions submission deadline 31 Aug 2024 | 4 articles | Viewed by 11067 | Submission Open
(This special issue belongs to the Section Cell Methods)
The Therapeutic Role of Extracellular Vesicles in COVID-19: Therapeutic and Preventive Mechanism
edited by
submission deadline 31 Aug 2024 | 3 articles | Viewed by 9809 | Submission Open
Keywords: extracellular vesicles; severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease 2019 (COVID-19); EV-associated COVID-19 pathogenesis; therapeutic intervention; treatment
(This special issue belongs to the Section Cell Microenvironment)
CRISPR-Based Genome Editing in Translational Research—Second Edition
edited by Jifeng Zhang, and
submission deadline 31 Aug 2024 | 6 articles | Viewed by 9026 | Submission Open
(This special issue belongs to the Section Cell and Gene Therapy)
Novel Insights into Molecular Mechanisms and Therapy of Asthma
edited by
submission deadline 31 Aug 2024 | 3 articles | Viewed by 5745 | Submission Open
(This special issue belongs to the Section Cellular Pathology)
Tuberculosis: From Pathogenesis to Targeted Therapies submission deadline 31 Aug 2024 | 3 articles | Viewed by 5172 | Submission Open
Keywords: tuberculosis; therapy; granuloma; antibiotics; host-directed
(This special issue belongs to the Section Cellular Pathology)
The Emerging Role of Astrocytes in Health and Neurological Diseases
edited by
submission deadline 31 Aug 2024 | 4 articles | Viewed by 4763 | Submission Open
Keywords: astrocyte network; gliotransmitters; astrocytes in learning and memory; astrocytes and the blood– brain barrier; astrocyte pathologies
(This special issue belongs to the Section Cells of the Nervous System)
The Ubiquitin–Proteasome System (UPS): Signaling Processes and Targeted Protein Degradation
edited by
submission deadline 31 Aug 2024 | 2 articles | Viewed by 4083 | Submission Open
Keywords: ubiquitin– proteasome system; ubiquitin ligases; targeted protein degradation; bispecific chimeras; novel chimera approaches
(This special issue belongs to the Section Cell Signaling)
The Pivotal Role of Tumor Stem Cells in Glioblastoma
edited by and Silvano J. Santini
submission deadline 31 Aug 2024 | 2 articles | Viewed by 2452 | Submission Open
Keywords: glioblastoma stem cells; resistance; cancer therapy; signaling pathways; tumor microenvironment
(This special issue belongs to the Section Stem Cells)
Oral Diseases: Biological and Molecular Pathogenesis
edited by
submission deadline 31 Aug 2024 | 2 articles | Viewed by 2014 | Submission Open
Keywords: pathogenesis; immunohistochemical and molecular alteration; oral diseases
(This special issue belongs to the Section Cellular Pathology)
Cell Adhesion/Migration in Tumor Metastasis
edited by
submission deadline 31 Aug 2024 | 1 articles | Viewed by 1828 | Submission Open
Keywords: cell adhesion; invasion; migration; extracellular matrix
(This special issue belongs to the Section Cell Motility and Adhesion)
New Strategies in Therapeutic Targets of Epilepsy
edited by Cameron S. Metcalf
submission deadline 31 Aug 2024 | 1 articles | Viewed by 1739 | Submission Open
Keywords: drug development; animal models; epilepsy; seizure; rare epilepsy; traumatic brain injury; epileptogenesis; disease modification; drug discovery
Skeletal Muscle Atrophy in Health and Disease: From Molecular Mechanisms to Therapeutic Opportunities submission deadline 31 Aug 2024 | 1 articles | Viewed by 1232 | Submission Open
Keywords: muscle atrophy; inactivity; ageing; sarcopenia; neuromuscular disorders
(This special issue belongs to the Section Cellular Pathology)
State of the Art in Stem Cell Culture for Regenerative Medicine submission deadline 31 Aug 2024 | 1 articles | Viewed by 1095 | Submission Open
Keywords: stem cells; cell culture techniques; regenerative medicine; tissue engineering
(This special issue belongs to the Section Stem Cells)
New Trends and Advances in Diagnosis and Prognosis of Head and Neck Cancer from Carcinogenesis to Future Molecular Targeted Therapies II submission deadline 31 Aug 2024 | 1 articles | Viewed by 1084 | Submission Open
Keywords: head and neck cancer; oral cancer; biomarker; prognosis; carcinogenesis; oral premalignant lesions; cancer stem cells; signaling pathways; molecular targeted therapy
(This special issue belongs to the Section Cellular Pathology)
Identifying Molecular or Cellular Level Pathomechanisms for Possible Therapeutic/Neuroprotective Interventions in Traumatic Brain Injury
edited by Krisztina Amrein and
submission deadline 31 Aug 2024 | 1 articles | Viewed by 1064 | Submission Open
Keywords: traumatic brain injury; head injury; clinical study; experimental model; neuroprotective intervention; therapy; pathomechanism; molecular; cellular
(This special issue belongs to the Section Cellular Pathology)
Mechanisms of Respiratory Diseases submission deadline 31 Aug 2024 | 1 articles | Viewed by 1029 | Submission Open
Keywords: cell death/stress; DNA/RNA sensor; cGAS/STING; inflammasome; microbiome; FMT or transfer of bacteria; metabolite; viral infection; emphysema; progressive fibrosis; innate immune response; defined inhibitors
Cellular and Clinical Mechanisms of Obesity and Diabetes and Their Complications submission deadline 31 Aug 2024 | 1 articles | Viewed by 972 | Submission Open
Keywords: obesity; type 1 diabetes; type 2 diabetes; metabolic disorders; complications; signaling pathways; pathophysiology; insulin; β -cell
(This special issue belongs to the Section Cellular Pathology)
Apoptosis in Cancers
edited by
submission deadline 31 Aug 2024 | 1 articles | Viewed by 840 | Submission Open
Keywords: apoptosis; cancer; resistance; caspase; bcl-2; p53; death receptor; small molecules; pharmacological targeting
Molecular Mechanisms and Clinical Treatments of Neurofibromatosis Type 1 Related Tumors
edited by and Federica Chiara
submission deadline 31 Aug 2024 | Viewed by 331 | Submission Open
Keywords: neurofibromatosis type 1; rare tumors; genetic syndrome; plexiform neurofibroma; malignant peripheral nerve sheath tumor; tumor suppressor; Ras signalling; tumor microenvironment; anti-neoplastic therapy; neoplastic transformation
(This special issue belongs to the Section Cells of the Nervous System)
Antiphospholipid Syndrome: Molecular Mechanisms and Novel Therapies
edited by and Simona Truglia
submission deadline 31 Aug 2024 | Viewed by 287 | Submission Open
Keywords: antiphospholipid syndrome; pathophysiology; management; treatment; antiphospholipid antibodies; molecular mechanisms; new biomarkers; diagnostic tests
(This special issue belongs to the Section Cellular Pathology)
Application of Gel-Based Proteomic Techniques: Unveiling the Molecular Tapestry
edited by Gagandeep Singh, Sandeep Kumar and Navleen Kaur
submission deadline 31 Aug 2024 | Viewed by 252 | Submission Open
(This special issue belongs to the Section Cellular Pathology)
Extracellular Vesicles in Tissue Repair and Regeneration
edited by
submission deadline 31 Aug 2024 | Viewed by 235 | Submission Open
Keywords: stem cells; extracellular vesicles; exosomes; regeneration; tissue repair; cell signaling
(This special issue belongs to the Section Tissues and Organs)
Stem Cell Therapy for Autoimmune Diseases—Second Edition submission deadline 31 Aug 2024 | Viewed by 195 | Submission Open
Keywords: autoimmune disease; stem cell therapy; hematopoietic stem cells; mesenchymal stem cells; MSC-derived secretome
Pulmonary Vascular Diseases in Extreme Environments: What Is Our Current Knowledge? submission deadline 31 Aug 2024 | Viewed by 166 | Submission Open
Keywords: pulmonary vascular diseases; pulmonary hypertension; pulmonary vascular vasoconstriction; pulmonary vascular remodeling; high altitude; hypoxia; cold exposure; cold environment; cellular and molecular mechanisms
(This special issue belongs to the Section Cells of the Cardiovascular System)
Advances and Breakthroughs in Stem Cell Research submission deadline 31 Aug 2024 | Viewed by 158 | Submission Open
Keywords: stem cell; induced pluripotent stem cell; iPSC; hematopoietic stem cell
(This special issue belongs to the Section Stem Cells)
Human Inborn Errors of Immunity
edited by
submission deadline 31 Aug 2024 | Viewed by 152 | Submission Open
Keywords: inborn errors of immunity (IEI); primary immune deficiencies (PID); human; immune cells; susceptibility to infections; pathogens; autoimmunity; autoinflammation; allergy; malignancies; gene therapy; cellular therapy; hematopoietic stem cell transplantation (HSCT); pharmacotherapy
(This special issue belongs to the Section Cellular Immunology)
Ovary and Brain—Series II
edited by Ilana I. Chefetz
submission deadline 31 Aug 2024 | Viewed by 151 | Submission Open
Keywords: ovary  ; ovary-brain communication  ; cancer  ; neurodegenerative diseases  ; mitochondrial dysfunction  ; cancer therapy  ; neurodegeneration mechanisms  ; therapeutic interventions  ; signaling pathways  ; molecular targets  ; precision medicine  ; biomarkers  ; cellular dynamics  ; translational research  ; addiction  ; reproductive health
(This special issue belongs to the Section Reproductive Cells and Development)
Extracellular Vesicles-Related Cellular Events in Neuronal Biology: Regulated Cell Death, Autophagy, Unfolded Protein Response, and Stress-Related Pathways submission deadline 31 Aug 2024 | Viewed by 151 | Submission Open
Keywords: extracellular vesicles; exosomes; regulated (or programmed) cell death; autophagy; homeostasis; stress; unfolded protein response (UPR) signaling pathways; endoplasmic reticulum (ER) stress; protein quality control (PQC); mitochondria; neuron; neurogenesis; neurodegeneration; brain
(This special issue belongs to the Section Autophagy)
Biomarkers for Therapeutic Advances in Breast Cancer submission deadline 31 Aug 2024 | Viewed by 147 | Submission Open
Keywords: breast cancer; biomarkers; therapeutic strategies; targeted therapy; breast cancer management
(This special issue belongs to the Section Cellular Pathology)
Understanding the Host/Microbe–Microbe Interactions in Human Diseases: From Imaging Technologies to Multi-omics Approaches
edited by
submission deadline 31 Aug 2024 | Viewed by 146 | Submission Open
Keywords: optical imaging; host/microbe– microbe interactions; microbial communities
(This special issue belongs to the Section Cell Methods)
Recent Advances in Tumor Immunological Microenvironment Research
edited by Yue Sun
submission deadline 31 Aug 2024 | Viewed by 141 | Submission Open
Keywords: tumor immune microenvironment; cancer immunotherapy; immune cells; immunosuppression; immune cell infiltration
(This special issue belongs to the Section Cell Microenvironment)
Gene Therapy for Rare Diseases
edited by
submission deadline 31 Aug 2024 | Viewed by 138 | Submission Open
Keywords: gene therapy; gene editing; rare diseases; CRISPR; viral vectors; base editing; prime editing
(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)
Mitochondrial Metabolism in Skeletal Muscle
edited by
submission deadline 31 Aug 2024 | Viewed by 134 | Submission Open
Keywords: skeletal muscle; mitochondria; mitochondrial dysfunction; mitochondrial diseases; mitochondrial biogenesis
State-of-the-Art Research on Histone Deacetylases (HDACs)
edited by
submission deadline 31 Aug 2024 | Viewed by 104 | Submission Open
Keywords: histone deacetylases; cancer; metabolism; immunotherapy; tumor microenvironment; DNA damage response; cell cycle
(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)
Recent Advances of Oxidative Stress and Inflammation in Diabetes—Volume II
edited by and Roni Weinberg Sibony
submission deadline 31 Aug 2024 | Viewed by 81 | Submission Open
Keywords: diabetes mellitus; oxidative stress; inflammation; hyperglycemia; reactive oxygen species; antioxidants; β cells; gallic acid
(This special issue belongs to the Section Cellular Metabolism)
Cellular Signaling and Therapeutic Approaches of Pulmonary Fibrosis
edited by Jennifer Speth
submission deadline 31 Aug 2024 | Viewed by 76 | Submission Open
Keywords: pulmonary fibrosis; resolution; cellular interactions
A Purview on Hippocampal Cells in Health and Diseases
edited by and Aarti Nagayach
submission deadline 10 Sep 2024 | 1 articles | Viewed by 767 | Submission Open
Keywords: hippocampal cell physiology; microglia; astroglia; neurodegenerative diseases; neurogenesis; action potential; neuropharmacology; neurotransmission
Understanding the Interplay between Autophagy and Neurodegeneration submission deadline 10 Sep 2024 | Viewed by 99 | Submission Open
Keywords: autophagy; neurodegeneration; ATG; protein aggregates; misfolded proteins; toxic stimuli
(This special issue belongs to the Section Autophagy)
Therapeutic Mechanism of Nervous System Inflammation submission deadline 15 Sep 2024 | 4 articles | Viewed by 11486 | Submission Open
Keywords: neuroinflammation; neurodegeneration; therapy; drug target; cell signalling; cells of nervous system
(This special issue belongs to the Section Cells of the Nervous System)
Cellular and Molecular Mechanisms of Cancer Invasion and Metastasis
edited by and
submission deadline 15 Sep 2024 | 6 articles | Viewed by 9536 | Submission Open
Keywords: cancer invasion; cancer metastasis; metastasis-related genes; metastasis biomarkers; novel targets; microenvironment; stromal factors
(This special issue belongs to the Section Cell Motility and Adhesion)
Rare Monogenic Diseases: Molecular Mechanism and Novel Therapies submission deadline 15 Sep 2024 | 2 articles | Viewed by 4708 | Submission Open
Keywords: rare diseases; monogenic diseases; genetics; molecular biology; molecular pathways; gene therapy; gene delivery; molecular medicine
(This special issue belongs to the Section Cellular Pathology)
Plant, Algae and Fungi Cell Biology: State-of-the-Art and Perspectives submission deadline 15 Sep 2024 | 1 articles | Viewed by 1922 | Submission Open
(This special issue belongs to the Section Plant, Algae and Fungi Cell Biology)
Endoplasmic Reticulum Stress in Neurodegenerative Diseases
edited by Dan Lindholm, and Vera Kovaleva
submission deadline 15 Sep 2024 | 1 articles | Viewed by 1901 | Submission Open
Keywords: endoplasmic reticulum; ER stress; Parkinson’ s disease; Huntington’ s disease; amyotrophic lateral sclerosis; Alzheimer’ s disease; neurodegenerative disorders
(This special issue belongs to the Section Cells of the Nervous System)
From Mechanisms to Therapeutics: Wnt Signaling in Cancer—Second Edition
edited by and
submission deadline 15 Sep 2024 | 1 articles | Viewed by 1189 | Submission Open
Keywords: Wnt; β -catenin; development; homeostasis; cancer; cancer stem cells (CSC); targeted cancer therapy; canonical Wnt signaling; non-canonical Wnt signaling
Advancing Human Cell Culture Towards More Physiological, Differentiated Tissues-Series II submission deadline 15 Sep 2024 | Viewed by 492 | Submission Open
Keywords: human cell modeling; stem cells; gene expression analyses in 3D; phenotypic analyses in 3D; drug screening; toxicity testing; optimization of human cell models; challenges of 3D models; animal replacement; infection biology
(This special issue belongs to the Section Tissues and Organs)
Crosstalk of Autophagy and Apoptosis: Recent Advances submission deadline 15 Sep 2024 | Viewed by 216 | Submission Open
Keywords: autophagy  ; apoptosis  ; cell signaling  ; mitochondria  ; MAMs  ; lipid rafts  ; cancer therapy  ; autoimmunity
(This special issue belongs to the Section Autophagy)
Diabetes-Induced Organ Damage: Cellular Mechanisms and Therapeutic Opportunities submission deadline 15 Sep 2024 | Viewed by 162 | Submission Open
Keywords: diabetes mellitus; vascular lesions; nephropathy; cardiomyopathy; neuropathy; retinopathy; therapeutic opportunities
(This special issue belongs to the Section Tissues and Organs)
Organellar Ca2+ Transport in Plant versus Animal Cells: Can We Learn from Each Other?
edited by Shey-Shing Sheu and Marc Freichel
submission deadline 15 Sep 2024 | Viewed by 137 | Submission Open
Keywords: organellar calcium transport; plant cells; animal cells; intracellular organelle communication; calcium signaling; mitochondria; organelle-targeted florescent Ca2+ indicators; super-resolution imaging
(This special issue belongs to the Section Cell Microenvironment)
Microproteins: From Identification to the Discovery of Their Functions
edited by
submission deadline 15 Sep 2024 | Viewed by 119 | Submission Open
Keywords: microproteins; short open reading frame-encoded peptides (SEPs); alternative proteins; functional characterization; mass spectrometry; transcriptomics; ribosome profiling; functional genomics; molecular mechanisms; cellular processes; signaling pathways; cellular homeostasis; protein– protein interactions
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