Special Issues

Cells publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Extracellular Vesicles and Drug Delivery System for Developing Cancer Therapeutics
edited by
submission deadline 20 Dec 2024 | Viewed by 85 | Submission Open
Keywords: extracellular vesicles; drug delivery; cancer therapeutics  
Glioblastoma: What Do We Know?
edited by
submission deadline 25 Dec 2024 | 3 articles | Viewed by 4443 | Submission Open
Keywords: carcinoma cell; diagnoses; molecular mechanism; cellular mechanism; signaling pathways; biomarkers; therapeutics
(This special issue belongs to the Section Cells of the Nervous System)
Fibrosis in Chronic Inflammatory Diseases submission deadline 25 Dec 2024 | 5 articles | Viewed by 4059 | Submission Open
Keywords: fibrosis; fibroblasts; myofibroblasts; inflammation; molecular pathways; pathogenetic mechanisms; therapeutic targets
(This special issue belongs to the Section Cellular Pathology)
Molecular and Cellular Basis of Sleep Disorders
edited by
submission deadline 25 Dec 2024 | 2 articles | Viewed by 2680 | Submission Open
Keywords: intermittent hypoxia; sleep fragmentation; sleep deprivation; OSA animal model; biomarkers
(This special issue belongs to the Section Cellular Pathology)
Nonalcoholic Fatty Liver Disease: From Mechanisms to Therapeutics
edited by and Alessandra Scamporrino
submission deadline 25 Dec 2024 | 2 articles | Viewed by 2651 | Submission Open
Keywords: NAFL; NASH; cirrhosis; molecular mechanisms; liver; gut; metabolic tissues
(This special issue belongs to the Section Cellular Metabolism)
Cellular Glycosphingolipids in Human Disease submission deadline 25 Dec 2024 | 1 articles | Viewed by 1970 | Submission Open
Keywords: glycosphingolipid; cancer; sphingolipid; signal transduction; epithelial to mesenchymal; ceramide; microdomain; chemoresistance; glucosylceramide; ganglioside; globoside; lactoside; neolactoside; sulfatide; GSL
(This special issue belongs to the Section Cellular Pathology)
Progress in Cancer Immunotherapies
edited by and Phuc Loi Luu
submission deadline 25 Dec 2024 | Viewed by 1053 | Submission Open
Keywords: cancer immunotherapy; immune checkpoint inhibitors; personalized immunotherapy; tumor microenvironment; biomarkers in immunotherapy
(This special issue belongs to the Section Cellular Immunology)
Mitochondrial Dysfunction in Neurodegeneration: A Translational Perspective
edited by Hemendra Vekaria
submission deadline 25 Dec 2024 | Viewed by 291 | Submission Open
Keywords: mitochondrial dysfunction; traumatic brain injury; secondary damage; bioenergetics
(This special issue belongs to the Section Cells of the Nervous System)
Cellular Mechanisms of Therapy Resistance and Metastasis in Breast Cancer
edited by Naseem Akhter and Sajad Ahmad Dar
submission deadline 25 Dec 2024 | Viewed by 170 | Submission Open
Keywords: single-cell sequencing; tumor microenvironment; immunotherapies; precision medicine; therapy resistance mechanisms
(This special issue belongs to the Section Cellular Pathology)
Novel Insights into Molecular Mechanisms and Therapy of Soft Tissue Sarcomas submission deadline 25 Dec 2024 | Viewed by 163 | Submission Open
Keywords: soft tissue sarcoma; molecular genetics; epigenetics  ; gene expression  ; ncRNA  ; post-transcriptional regulations  ; post-translational modifications  ; targeted therapy  ; drug resistance  ; molecular biomarkers
(This special issue belongs to the Section Tissues and Organs)
Therapeutic Applications of Magnetotactic Bacteria and Magnetosomes: State-of-the-Art and Perspectives
edited by
submission deadline 25 Dec 2024 | Viewed by 89 | Submission Open
Keywords: biomedical applications; biotechnology; magnetite nanocrystals; magnetosomes; magnetotactic bacteria; nanotechnology; nanotargeting
(This special issue belongs to the Section Cellular Biophysics)
Cellular and Molecular Mechanisms in Gynecological Disorders
edited by
submission deadline 30 Dec 2024 | 3 articles | Viewed by 2397 | Submission Open
Keywords: uterus; ovary; breast; cervix; cancer; endometriosis; leiomyoma; adenomyosis; polycystic ovary syndrome; female infertility; pathways; cell atlas; transcriptome; epigenome
(This special issue belongs to the Section Reproductive Cells and Development)
Mechanisms of Antimicrobial Treatment in Human Diseases
edited by Paolo Gaibani
submission deadline 30 Dec 2024 | 1 articles | Viewed by 956 | Submission Open
Keywords: multidrug resistance; epidemiology; novel antimicrobial resistance traits
Modeling Developmental Processes and Disorders in Zebrafish submission deadline 31 Dec 2024 | 10 articles | Viewed by 24063 | Submission Open
(This special issue belongs to the Section Cellular Biophysics)
Innate Immunity in Health and Disease submission deadline 31 Dec 2024 | 7 articles | Viewed by 16778 | Submission Open
Keywords: innate immunity; homeostasis; disease; inflammation; PAMPs; DAMPs; pattern recognition receptors; phagocytes; innate lymphoid cells; neutrophils
(This special issue belongs to the Section Cellular Immunology)
Understanding Aging Mechanisms to Prevent Age-Related Diseases
edited by Pierre Jouanny, Sonia Hammami, and
submission deadline 31 Dec 2024 | 6 articles | Viewed by 13007 | Submission Open
(This special issue belongs to the Section Cellular Aging)
Potential of CAR-Based Cellular Immunotherapy for Non-oncologic Disorders submission deadline 31 Dec 2024 | 3 articles | Viewed by 11535 | Submission Open
Keywords: adoptive cell transfer; CAR-T cells; cell engineering; CAR products; CAR-T cell therapy; non-oncologic disorders; autoimmune diseases; cardiometabolic diseases; inflammatory organ fibrosis; senescent cell pathologies; infections
(This special issue belongs to the Section Cellular Immunology)
Model Systems for Human Disease and Medicine: From Advanced Cell and Tissue Culture to In Silico Methods
edited by
submission deadline 31 Dec 2024 | 5 articles | Viewed by 11023 | Submission Open
Keywords: modelling; human model systems; in vitro; cells; stem cells; pluripotent stem cells; iPSC; tissue; organoid; organ-on-a-chip; cell-on-a-chip; in silico; disease; cancer; regenerative medicine; diagnostics; therapeutics
(This special issue belongs to the Section Cell Methods)
Emerging Roles of Glial Cells in Human Health and Disease submission deadline 31 Dec 2024 | 4 articles | Viewed by 8100 | Submission Open
Keywords: neurodegenerative diseases; glia cells; astrocyte; microglia; stroke; pain; epilepsy; trauma; demyelinating diseases’ inflammatory diseases; satellite glia; Schwann cells; enteric glia
(This special issue belongs to the Section Cells of the Nervous System)
Cellular and Molecular Basis of Wound Healing II submission deadline 31 Dec 2024 | 3 articles | Viewed by 7415 | Submission Open
Keywords: scratch wound assay; Ca2+ signaling; burns and wound healing; keratinocytes biology; matrix remodelling; inflammation and wound healing; gene therapy in wound healing; wound management; wound healing; tissue regeneration; cell and molecular biology; wounds; difficult-to-heal wounds; chronic/acute wounds
(This special issue belongs to the Section Cellular Pathology)
Recent Research on the Role of Mitochondria in Neurodegeneration
edited by
submission deadline 31 Dec 2024 | 3 articles | Viewed by 5614 | Submission Open
Keywords: mitochondrial; neurodegeneration; metabolism; mitophagy; apoptosis
(This special issue belongs to the Section Cells of the Nervous System)
Select Topics in Molecular and Cellular Mechanisms of Mammalian Reproduction
edited by Zhengui Zheng, and Liang Ma
submission deadline 31 Dec 2024 | 3 articles | Viewed by 4885 | Submission Open
Keywords: reproductive organ development; sexual differentiation; reproductive tract function; fertilization; implantation; placentation; parturition; lactation
(This special issue belongs to the Section Reproductive Cells and Development)
Advances in Zebrafish Cardiac Disease Models
edited by
submission deadline 31 Dec 2024 | 2 articles | Viewed by 4512 | Submission Open
Keywords: zebrafish; heart; cardiomyocytes; heart disease; cardiac hypertrophy; regenerative medicine; cardiac regeneration; translational models
(This special issue belongs to the Section Cells of the Cardiovascular System)
Cancer Immunotherapy Harnessing Innate and Adaptive Immune Effector Cells and PD-1 Immune Checkpoint Inhibitors
edited by
submission deadline 31 Dec 2024 | 3 articles | Viewed by 4106 | Submission Open
Keywords: PD-1 immune checkpoint; CAR-T cells; γ δ T cells; NK cells
(This special issue belongs to the Section Cellular Immunology)
Molecular and Cellular Mechanisms of Lymphomas submission deadline 31 Dec 2024 | 4 articles | Viewed by 4038 | Submission Open
Keywords: lymphoma; pathogenes and lymphomas; molecular pathogenesis; molecular diagnosis; cellular or gene-targeted therapy; cell metabolism
(This special issue belongs to the Section Cellular Pathology)
Exclusive Review Papers in Autophagy—Second Edition
edited by
submission deadline 31 Dec 2024 | 2 articles | Viewed by 3588 | Submission Open
Keywords: biquitination; autophagy; peroxisomes; macroautophagy; pexophagy; mitophagy; lysosome; vacuole; organellar homeostasis; posttranslational modifications; lipids; signaling cascades
(This special issue belongs to the Section Autophagy)
Redox and Metabolic Profile of Cancer
edited by
submission deadline 31 Dec 2024 | 2 articles | Viewed by 3477 | Submission Open
Keywords: cancer; metabolism; redox biology; redox-metabolic reprogramming; reactive species: oxygen; nitrogen; sulfur; etc; cancer microenvironment; cancer-tissue cooperation; mitochondria
(This special issue belongs to the Section Cellular Metabolism)
Human Dental Pulp Stem Cells: Isolation, Cultivation and Applications
edited by
submission deadline 31 Dec 2024 | 2 articles | Viewed by 3118 | Submission Open
Keywords: dental pulp stem cell; stem cell engineering; mesenchymal stem cell; detin-pulp complex regeneration; dentinogenesis; odontoblastic dental pulp stem cell regeneration; dental pulp stem cell in neural regeneration
(This special issue belongs to the Section Stem Cells)
Understanding the Extracellular Vesicles (EVs)-Mediated Horizontal Transfer of Non-coding RNAs submission deadline 31 Dec 2024 | 1 articles | Viewed by 2366 | Submission Open
Keywords: extracellular vesicles; non-coding RNA  ; horizontal transfer; RNA loading; RNA binding proteins
mTOR Signaling in Metabolism and Cancer 2.0
edited by and
submission deadline 31 Dec 2024 | 1 articles | Viewed by 2149 | Submission Open
Keywords: mTOR; metabolism; cancer; Akt
(This special issue belongs to the Section Cell Proliferation and Division)
Gastrointestinal Disease: From Cellular Mechanisms to Targeted Therapy submission deadline 31 Dec 2024 | 1 articles | Viewed by 2091 | Submission Open
Keywords: gastrointestinal cancer; gastric cancer; colorectal cancer; esophageal cancer; liver cancer; pancreatic cancer; inflammatory bowel disease; miRNAs; in vitro and in vivo models; molecular networks; molecular pathways; translational medicine; epithelial barrier functions/processes
(This special issue belongs to the Section Cellular Pathology)
Mitochondrial Biology and Pathophysiology
edited by and Laura Formentini
submission deadline 31 Dec 2024 | 1 articles | Viewed by 2072 | Submission Open
Keywords: mitochondria; age-related diseases; animal models; cell death; immune responses; metabolic responses; mitochondrial structure; dynamics and function proteostasis
(This special issue belongs to the Section Cellular Pathology)
Head and Neck Squamous Cell Carcinomas: Biomarkers and Cellular Mechanisms towards a Precision Therapy
edited by
submission deadline 31 Dec 2024 | 1 articles | Viewed by 1996 | Submission Open
Keywords: head and neck cancer; biomarkers; prognosis; precision therapy; immunotherapy; translational research; immune contexture
(This special issue belongs to the Section Cell Methods)
Molecular and Biochemical Mechanisms Elucidating Growth and Cellular Stress Responses of Microalgae
edited by and Damar Lizbeth López-Arredondo
submission deadline 31 Dec 2024 | 1 articles | Viewed by 1973 | Submission Open
Keywords: microalgal physiology; cellular stress; organic pollutants; inorganic pollutants; nano & micro plastics; nutrient limitations; growth promotors; carbon fixation; carbon flux channelization; bioenergy and bioproducts; biorefinery; molecular mechanisms; omics technologies
(This special issue belongs to the Section Plant, Algae and Fungi Cell Biology)
Critical Targets and Therapeutic Strategies of Breast Cancer submission deadline 31 Dec 2024 | 1 articles | Viewed by 1776 | Submission Open
Keywords: biomarkers; microenvironment; subtypes; dormancy; therapy; resistance
Bone Regeneration and Repair: Replacing What Has Been Lost through Science
edited by Paolo Savadori
submission deadline 31 Dec 2024 | 1 articles | Viewed by 1724 | Submission Open
Keywords: bone; regenerative; bone defect; tissue engineering; histology; animal models; bone biology; 3D printing; biomaterials; bone surgery
Signaling Pathways and Mechanisms in Cancer Therapy Resistance submission deadline 31 Dec 2024 | 1 articles | Viewed by 1650 | Submission Open
Keywords: cancer therapy; therapy resistance; molecular mechanisms; cell signaling pathways; genetic and epigenetic modifications; combination therapies
(This special issue belongs to the Section Cellular Pathology)
Advances in Retinal Disease Treatments Based on Cell Therapy and Regenerative Medicine submission deadline 31 Dec 2024 | 1 articles | Viewed by 1647 | Submission Open
Keywords: retinal diseases; cell therapy; regenerative medicine; visual function restoration; tissue regeneration; neuronal survival; promising therapeutic strategies
(This special issue belongs to the Section Cell Methods)
Molecular Mechanisms Involved in Musculoskeletal and Other Tissue Injuries and Disruptions—Regenerative Potential of Exercise submission deadline 31 Dec 2024 | 1 articles | Viewed by 1592 | Submission Open
Keywords: tissue injury; tissue regeneration; growth factors; inflammation; oxidative stress; metabolic stress; myokines; adipokines; neurokines; hypertrophy; biochemical pathways; skeletal muscles; liver/hepatic regeneration; brain/neuroplasticity; adipose tissue; varia
(This special issue belongs to the Section Tissues and Organs)
The Double Face of Smooth Muscle Cells in Vascular Biology—Friends or Foes, Damage or Regeneration?
edited by
submission deadline 31 Dec 2024 | 1 articles | Viewed by 1566 | Submission Open
Keywords: vascular smooth muscle cells; phenotypic modulation; vascular disease; stem cell differentiation; vascular tissue engineering; regenerative medicine
(This special issue belongs to the Section Cells of the Cardiovascular System)
Radiation-Induced Brain Injury: Molecular Mechanisms and Therapeutic Strategies
edited by
submission deadline 31 Dec 2024 | 2 articles | Viewed by 1502 | Submission Open
Keywords: radiation injury; brain; neurological and neuropsychiatric disorders; molecular mechanisms; novel therapeutic approaches
(This special issue belongs to the Section Cells of the Nervous System)
Formation, Aggregation, Persistence, and Maturation of NETs
edited by , , and Maximilian Dölling
submission deadline 31 Dec 2024 | 1 articles | Viewed by 1114 | Submission Open
Keywords: mechanisms of NET formation; NETs in diseases; degradation of NETs; NET therapeuticals; benefical NETs
(This special issue belongs to the Section Cellular Immunology)
The Role of MDM2 in Tumor Biology and Cancer Therapy submission deadline 31 Dec 2024 | 1 articles | Viewed by 998 | Submission Open
Keywords: MDM2; p53; targeted therapy; imunotherapy; drug resistance
(This special issue belongs to the Section Cell and Gene Therapy)
Cell–Cell Interactome-Based Therapies for Osteosarcoma
edited by and Javier Munoz
submission deadline 31 Dec 2024 | 1 articles | Viewed by 856 | Submission Open
Keywords: osteosarcoma; cell– cell interactions; microenvironment; metastases; resistance; chemotherapy; immune checkpoints
(This special issue belongs to the Section Cell Microenvironment)
Kynurenic Acid: Unveiling Its Impact on the Brain’s Neurotransmission and Neurological Disorders
edited by Korrapati V. Sathyasaikumar, Sarah Beggiato and
submission deadline 31 Dec 2024 | 1 articles | Viewed by 803 | Submission Open
Keywords: kynurenic acid; cognition; aging; neuromodulation; neurodegeneration; neurodevelopment; neuroinflammation; tryptophan catabolism
(This special issue belongs to the Section Cell Signaling)
Updates on the Mechanisms and Therapies of Cardiometabolic Disease submission deadline 31 Dec 2024 | 1 articles | Viewed by 703 | Submission Open
Keywords: cardiovascular disease; atherosclerosis; metabolic disease; hyperlipidemia; diabetes; proatherogenic lipoproteins; drug discovery; gene therapy/gene editing; ASO; mAb
(This special issue belongs to the Section Cells of the Cardiovascular System)
New Insights into Therapeutic Targets for Cardiovascular Diseases submission deadline 31 Dec 2024 | 1 articles | Viewed by 677 | Submission Open
Keywords: cardiovascular disease prevention and treatment; ischemic cardiomyopathies; endothelium injury/damage; cardiac remuscularization and repair; cardiovascular/angiogenic targets and biomarkers; targeted delivery platforms/systems/formulations; precision nanomedicine; targeted nano-theranostic applications; localized and systemic administration; safety and efficacy
(This special issue belongs to the Section Cells of the Cardiovascular System)
From Research to Legalization: How Cannabis Exploits the Endocannabinoid System
edited by Erik Keimpema and Tibor Harkany
submission deadline 31 Dec 2024 | 1 articles | Viewed by 510 | Submission Open
Keywords: endocannabinoids; cannabis; legalization; THC; disease; development
Second Edition of Advances in Adipose Tissue Biology
edited by
submission deadline 31 Dec 2024 | 1 articles | Viewed by 455 | Submission Open
Keywords: adipocyte differentiation; progenitors; and stem cells; adipokines; myokines; hepatokines; cytokines; cellular signaling; and molecular crosstalk; white adipose tissue (WAT) and brown adipose tissue (BAT); beige fat and browning of WAT; research techniques and methodologies; diagnostics and therapeutics; genomics; metabolomics; other ‘ omics’ technologies; metabolic syndrome; obesity; insulin resistance; cancer
(This special issue belongs to the Section Tissues and Organs)
Application of Gel-Based Proteomic Techniques: Unveiling the Molecular Tapestry
edited by Gagandeep Singh, Sandeep Kumar and Navleen Kaur
submission deadline 31 Dec 2024 | Viewed by 361 | Submission Open
(This special issue belongs to the Section Cellular Pathology)
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