Special Issues

Cells publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Angiogenesis in Cancer: Signalling Pathways of Angiogenesis submission deadline 31 Oct 2024 | Viewed by 204 | Submission Open
Keywords: angiogenesis; cancer; signal
(This special issue belongs to the Section Cell Proliferation and Division)
Insight into Lipid Droplets
edited by
submission deadline 31 Oct 2024 | Viewed by 142 | Submission Open
Keywords: lipid droplet; lipid droplet protein; lipid droplet biogenesis; lipid droplet growth; lipid droplet degradation; lipid droplet– organelle interaction; lipid metabolism; lipid-metabolism-related diseases
(This special issue belongs to the Section Cellular Biophysics)
Vascular Dysfunction in Alzheimer’s Disease submission deadline 31 Oct 2024 | Viewed by 132 | Submission Open
Keywords: vasculopathy in AD; tight junction loss; retinal vascular abnormalities; vascular permeability; vascular amyloidosis; vascular inflammation
(This special issue belongs to the Section Cellular Aging)
Hedgehog Signaling in Myelin Diseases and Inflammatory Disorders of the Nervous System—Second Edition submission deadline 31 Oct 2024 | Viewed by 130 | Submission Open
Keywords: Hedgehog signaling; myelination; myelin repair; neuroinflammation; glial cells; blood– brain barrier; blood– nerve barrier; hedgehog modulators; cell therapy; nerve injury
Intracellular Mechanism in Differentiation, Proliferation and Cell Death submission deadline 1 Nov 2024 | Viewed by 453 | Submission Open
Keywords: intracellular mechanism; molecular pathway; differentiation; proliferation; cell death; apoptosis; necrosis; inflammation; epigenomics; proteomics
(This special issue belongs to the Section Cellular Pathology)
Neurobiology of Chronicity of Pain submission deadline 4 Nov 2024 | Viewed by 139 | Submission Open
Keywords: pain; chronicity; synapses; receptors; brain circuits; depression; comorbidities
(This special issue belongs to the Section Cells of the Nervous System)
Molecular Signaling Pathways Associated with Neurotoxicity submission deadline 10 Nov 2024 | 2 articles | Viewed by 4811 | Submission Open
Keywords: neurotoxicity; signal transduction; heavy metals; environmental toxicants; neurodegeneration
(This special issue belongs to the Section Cells of the Nervous System)
Organelle Contact and Its Physiological Implications submission deadline 10 Nov 2024 | Viewed by 383 | Submission Open
Keywords: inter-organelle communication; membrane contact sites; organelle dynamics; mitochondria-associated membranes; cellular homeostasis
Sickle Cell Disease: Pathogenesis, Diagnosis and Treatment
edited by Vivien Sheehan and Ben Kopp
submission deadline 10 Nov 2024 | Viewed by 185 | Submission Open
Keywords: sickle cell disease; vaso-occlusive events; acute chest syndrome; omics; gene therapy; red cell rheology; microfluidics
(This special issue belongs to the Section Cellular Pathology)
PI3K/AKT/mTOR Signaling Network in Human Health and Diseases 2.0 submission deadline 15 Nov 2024 | 7 articles | Viewed by 19361 | Submission Open
Keywords: acne; ageing; Akt; Alzheimer’ s disease; autophagy; autoimmunity; PI3K; mTOR; cancer; cardiovascular diseases; diabetes; growth; hamartoma; hypertrophy; inflammation; neurologic; tuberous sclerosis; systemic sclerosis; obesity; Parkinson’ s disease; psoriasis; atopic dermatitis; burns/wound healing; targeted therapy; natural products; biologics
(This special issue belongs to the Section Cell Signaling)
The Crosstalk between Malignant Cells and Their Microenvironment
edited by
submission deadline 15 Nov 2024 | 5 articles | Viewed by 13028 | Submission Open
Keywords: tumor microenvironment; tumor hypoxia; extracellular acidosis; angiogenesis; stromal cells; immune cells; extracellular vescicles; extracellular matrix
(This special issue belongs to the Section Cell Microenvironment)
The Role of PPARs in Disease - Volume III submission deadline 15 Nov 2024 | 9 articles | Viewed by 8694 | Submission Open
Keywords: PPAR; immune function; liver; adipose tissue; cardiovascular system; muscle; neurological and psychiatric diseases; cancer; transcriptional regulation; ligands; agonists/antagonists
Autophagy Meets Aging 2024 submission deadline 15 Nov 2024 | 2 articles | Viewed by 3575 | Submission Open
Keywords: aging; autophagy; cellular quality control; mitochondrial dysfunction; redox biology; extracellular vesicles trafficking; inflammation; biomarkers; omics; behavioral and pharmacological interventions
(This special issue belongs to the Section Autophagy)
The Pathogenetic Triad of Chronic Airway Diseases—Inflammation, Tissue Destruction, and Airway Remodeling
edited by and Michael Wegmann
submission deadline 15 Nov 2024 | 1 articles | Viewed by 1966 | Submission Open
Keywords: chronic lung disease; inflammation; signaling pathway; disease models; tissue destruction; airway remodeling; epigenetics
(This special issue belongs to the Section Cellular Immunology)
Advances in the Research of a Key Molecule in Periostin
edited by and Nobutaka Koibuchi
submission deadline 15 Nov 2024 | 2 articles | Viewed by 1740 | Submission Open
Keywords: splicing variant; cancer; inflammatory disease; bone and dental disease; retinopathy
Intervertebral Disc Degeneration and Regeneration: New Molecular Mechanisms and Therapeutics—Second Edition
edited by
submission deadline 15 Nov 2024 | 1 articles | Viewed by 1182 | Submission Open
Keywords: spine; intervertebral disc; biomaterial; stem cell; gene therapy
(This special issue belongs to the Section Cellular Pathology)
Epigenetic Mechanisms and Aging: Model Organism Drosophila
edited by
submission deadline 15 Nov 2024 | Viewed by 158 | Submission Open
Keywords: drosophila melanogaster; model organism; cell biology; developmental biology; genetics; molecular biology; cell signaling; cellular differentiation; cell proliferation; cell cycle; cellular morphogenesis; cell-cell communication; stem cells; cell migration; apoptosis; cytoskeleton; cell adhesion; cellular metabolism; functional genomics; CRISPR/Cas9 in drosophila; omics technologies; disease models; drug discovery; regeneration; genetic screens; cellular stress responses
(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)
Hypoxia Pathway Proteins in the Immune System: Regulation, Disease, and Therapeutics
edited by Ben Wielockx
submission deadline 15 Nov 2024 | Viewed by 136 | Submission Open
Keywords: hypoxia; oxygen sensors; immune system; HIF; disease mechanisms; therapeutics; inflammation; autoimmunity; cancer immunology
(This special issue belongs to the Section Cellular Immunology)
Spotlight on Neuromuscular Diseases: Pathomechanisms and New Therapeutic Targets submission deadline 20 Nov 2024 | 5 articles | Viewed by 11443 | Submission Open
Keywords: neuromuscular disorders; myositis; myasthenia gravis; genetic mutations; muscle inflammation; de-/regeneration; immune cell infiltration; new therapy options; targeted therapy
(This special issue belongs to the Section Cellular Pathology)
The Role of Macrophages and Neutrophils in Chronic Inflammation-Related Disorders submission deadline 20 Nov 2024 | 4 articles | Viewed by 5900 | Submission Open
Keywords: chronic inflammation; neutrophils; macrophages; Alzheimer’ s disease; aging; cardiovascular diseases; obesity; cancer; fibrosis; tissue injury and repair
(This special issue belongs to the Section Cellular Immunology)
Regulatory Programs of Skeletal Muscle Repair and Regeneration submission deadline 20 Nov 2024 | 2 articles | Viewed by 5132 | Submission Open
Neural Mechanisms of Eating Disorders and Obesity
edited by Xiaobing Zhang
submission deadline 20 Nov 2024 | 1 articles | Viewed by 1139 | Submission Open
Keywords: food intake; food reward; feeding motivation; eating disorders; obesity; neural circuits; neural plasticity; binge-eating disorder; anorexic disorder; high-fat diet; stress
(This special issue belongs to the Section Cellular Metabolism)
Molecular and Cellular Mechanisms of Marfan Syndrome submission deadline 20 Nov 2024 | Viewed by 302 | Submission Open
Keywords: Marfan syndrome; aortic aneurysm; aortic dissection; TGFβ ; BMP; matrix metalloproteinase; NO synthase; mitochondrial dysfunction; oxidative stress; endothelium; aortic vascular smooth muscle cells; phenotypic switching; adventitia; hemodynamics; gene therapy; connective tissue disease
(This special issue belongs to the Section Cellular Pathology)
Drosophila: Contribution to Cell Research
edited by
submission deadline 20 Nov 2024 | Viewed by 276 | Submission Open
Keywords: Drosophila; cell research; cell biology; gene function; disease processes; fruit fly
Macrophages in Cancer: Immunosuppression, Immunoregulation, and Immunotherapy
edited by Abdullah Saeed
submission deadline 20 Nov 2024 | Viewed by 197 | Submission Open
Keywords: macrophage; immunosuppression; immunoregulation; immunotherapy; tumor immune microenvironment
(This special issue belongs to the Section Cell Microenvironment)
Advances in the Study of Natural Killer (NK) Cells
edited by Fuguo Liu, Mubin Tarannum and Yingjie Zhao
submission deadline 25 Nov 2024 | 4 articles | Viewed by 10259 | Submission Open
Keywords: natural killer cells; chimeric antigen receptor; immunotherapy; activating receptors; inhibitory receptors
(This special issue belongs to the Section Cellular Immunology)
Cell Biology Research in Model Organism Drosophila submission deadline 25 Nov 2024 | 3 articles | Viewed by 5914 | Submission Open
Keywords: drosophila melanogaster; model organism; cell biology; developmental biology; genetics; molecular biology; cell signaling; cellular differentiation; cell proliferation; cell cycle; cellular morphogenesis; cell-cell communication; stem cells; organelle biology; mitosis; meiosis; cell migration; apoptosis; cytoskeleton; cell adhesion; membrane trafficking; intracellular transport; epigenetics; genome stability; cellular metabolism; immunity in drosophila; neurobiology; RNA biology; protein folding; functional genomics; CRISPR/Cas9 in drosophila; omics technologies; disease models; drug discovery; regeneration; genetic screens; cellular stress responses
Cellular and Molecular Basis in Chronic Kidney Disease submission deadline 25 Nov 2024 | 4 articles | Viewed by 5726 | Submission Open
Keywords: CKD; renal inflammation; renal fibrosis; RAAS; aldosterone; TGF-B1; uremic toxins; hypertension; GFR; albuminuria
(This special issue belongs to the Section Cellular Pathology)
Natural Products and Their Derivatives in Immunity
edited by
submission deadline 25 Nov 2024 | 1 articles | Viewed by 1380 | Submission Open
Keywords: natural products; immunomodulatory; diseases; molecular mechanism of immunity
(This special issue belongs to the Section Cellular Immunology)
Immunotherapeutic Challenges and Treatment Resistance in Glioma
edited by Kristen A. Batich
submission deadline 29 Nov 2024 | Viewed by 190 | Submission Open
Keywords: antigen presentation; innate immunity; cellular immunotherapy; treatment resistance
(This special issue belongs to the Section Cells of the Nervous System)
Structures, Regulation, Signaling, and Physiological Functions of Adhesion G-Protein Coupled Receptors submission deadline 30 Nov 2024 | 11 articles | Viewed by 29143 | Submission Open
Keywords: adhesion GPCR; physiology; animal models; clinical studies; signaling; ligands; structures; computational
(This special issue belongs to the Section Cell Signaling)
Genetics and Pathomechanisms of Amyotrophic Lateral Sclerosis (ALS)
edited by
submission deadline 30 Nov 2024 | 8 articles | Viewed by 15690 | Submission Open
Keywords: genetics of ALS/FTD; ER stress and UPR; mitochondria and mitochondrial-associated membranes; Ca2+ signaling; excitotoxicity/neuronal networks; synaptic dysfunction; therapeutic strategies
(This special issue belongs to the Section Cellular Pathology)
Injury, Neurodegeneration, and Regeneration of Retinal Ganglion Cells
edited by , Lin Gan, and Yongling Zhu
submission deadline 30 Nov 2024 | 3 articles | Viewed by 7524 | Submission Open
Keywords: retinal ganglion cells; RGC development; RGC degeneration; RGC and axonal regeneration; molecular mechanism; RGC survival; retina; signal transduction pathways; RGC injury; glaucoma; RGC transplantation; retinal organoid; optic neuropathy; retinal circuits
(This special issue belongs to the Section Cells of the Nervous System)
Recent Advances in Research on Chromosome Abnormalities and Genomic Disorders
edited by and Vijay S. Tonk
submission deadline 30 Nov 2024 | 1 articles | Viewed by 6589 | Submission Open
Keywords: genomic testing; whole-exome sequencing; microarray analysis; cytogenetics; DNA diagnosis; DNA variation; DNA variant qualification; genetic disease
(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)
Genetic Disorders in Breast and Ovarian Cancer
edited by Marek Nowak and Miłosz Wilczyński
submission deadline 30 Nov 2024 | 3 articles | Viewed by 6083 | Submission Open
Keywords: ovarian cancer; breast cancer; oncogenesis; genetic disorders; targeted therapy
(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)
State-of-the-Art of Cell Cultures in Drug Validation and Toxicity Assessment submission deadline 30 Nov 2024 | 2 articles | Viewed by 4343 | Submission Open
Keywords: human in vitro models; toxicity testing; drug development; mandatory requirements; regulatory approval; standardization; validation
(This special issue belongs to the Section Cell Methods)
State of the Art in Stem Cell Culture for Regenerative Medicine submission deadline 30 Nov 2024 | 2 articles | Viewed by 3648 | Submission Open
Keywords: stem cells; cell culture techniques; regenerative medicine; tissue engineering
(This special issue belongs to the Section Stem Cells)
Male Infertility Update: Current Knowledge on Etiology, Comorbidities, Diagnosis and Treatment: Preclinical Topics submission deadline 30 Nov 2024 | 3 articles | Viewed by 3473 | Submission Open
Keywords: male infertility; diagnosis; treatment; etiology; pre-testicular/testicular/post-testicular causes; genetic causes; seminal parameters; hormonal parameters; ultrasound; general health; azoospermia
(This special issue belongs to the Section Reproductive Cells and Development)
Organoids as an Experimental Tool
edited by , and Anjali A. J. Roeth
submission deadline 30 Nov 2024 | 3 articles | Viewed by 3305 | Submission Open
Keywords: organoid culture models; primary cell and cancer spheroid models; organotypic models; organoid research for animal replacement (3R); chip-based methods; general 3D cell culture protocols; in silico approaches; microinjection apical-out organoids; organoid manipulation techniques; organoid intelligence; organoids in diagnostics; imaging in organoids
(This special issue belongs to the Section Tissues and Organs)
Effects of Microglia Changes on Neuroinflammation and Neurodegeneration
edited by Chi-Su Yoon and
submission deadline 30 Nov 2024 | 1 articles | Viewed by 2696 | Submission Open
Keywords: microglia; neuroinflammation; neurodegenerative disease; neurodegeneration; central nervous system
(This special issue belongs to the Section Cells of the Nervous System)
Metabolic Regulation of Hematopoietic Stem Cells
edited by
submission deadline 30 Nov 2024 | 1 articles | Viewed by 2266 | Submission Open
Keywords: hematopoietic stem cells; metabolic regulation; mitochondrial function; self-renewal and differentiation; quiescence; energy metabolism; HSC exhaustion; aging; bm niche; leukemia stem cells (LSCs)
(This special issue belongs to the Section Stem Cells)
Role of Hyaluronan in Human Health and Disease
edited by Barbara Triggs-Raine and
submission deadline 30 Nov 2024 | 2 articles | Viewed by 2113 | Submission Open
Keywords: hyaluronan; hyaluronidases; hyaluronan-binding proteins; hyaluronan receptors; fibrosis; cancer; development; immune function
(This special issue belongs to the Section Cellular Pathology)
Behind and beyond Neuroinflammation: State of the Art and New Perspectives submission deadline 30 Nov 2024 | 1 articles | Viewed by 1870 | Submission Open
Keywords: astrocytes; microglia; neurons; intercellular interactions; neurodegeneration; neuroprotection; extracellular matrix
(This special issue belongs to the Section Cells of the Nervous System)
Retinal Disorders: Cellular Mechanisms and Targeted Therapy
edited by
submission deadline 30 Nov 2024 | 1 articles | Viewed by 1382 | Submission Open
Keywords: inherited eye diseases; genome; omics; gene editing; iPS cells; animal models; single cell analysis; AI; epigenetics
(This special issue belongs to the Section Cellular Pathology)
Advances in Musculoskeletal Tissue Regeneration Using Mesenchymal Stromal/Stem Cells, Biomaterials, and Signaling Molecules: Second Edition submission deadline 30 Nov 2024 | 1 articles | Viewed by 1011 | Submission Open
Keywords: mesenchymal stromal/stem cells; extracellular vesicles; biomaterials; signalling molecules; microphysiological systems; musculoskeletal regeneration; immunomodulation; cell therapy; tissue engineering
(This special issue belongs to the Section Stem Cells)
Regulation of Receptor Tyrosine Kinase Signaling and Its Implication in Cancer
edited by
submission deadline 30 Nov 2024 | 1 articles | Viewed by 869 | Submission Open
Keywords: RTKs; EGFR family; PDGFR family; FGF receptor family; VEGFR family; growth factors; phosphorylation; cell signaling; cell cycle; cancer; targeted cancer therapy; the antibody-based cancer therapies; small molecule-based tyrosine kinase inhibitor (TKI)
(This special issue belongs to the Section Cell Signaling)
The Role of Oxidative Stress in Cardiovascular Diseases—2nd Edition
edited by and
submission deadline 30 Nov 2024 | 1 articles | Viewed by 520 | Submission Open
Keywords: oxidative stress; antioxidants; apoptosis; atherosclerosis; blood vessel; heart failure; hypertension; inflammation; mitochondria; microcirculation; reactive oxygen species
(This special issue belongs to the Section Cells of the Cardiovascular System)
New Discoveries in Calcium Signaling-Related Neurological Disorders
edited by Matheus De Castro Fonseca
submission deadline 30 Nov 2024 | Viewed by 405 | Submission Open
Keywords: Ca2+ signaling; neurons; neurological disorders; intracellular signaling; synaptic dysfunction
(This special issue belongs to the Section Cells of the Nervous System)
Klinefelter Syndrome and Other Sex Chromosome Variations: Cellular Manifestations and Clinical Implications
edited by Stanley J. Kogan and
submission deadline 30 Nov 2024 | Viewed by 362 | Submission Open
Keywords: klinefelter syndrome; sex chromosome variations; fertility status
(This special issue belongs to the Section Reproductive Cells and Development)
Mitochondria Meets Oxidative Stress submission deadline 30 Nov 2024 | Viewed by 358 | Submission Open
Keywords: mitochondria; oxidative stress; reactive oxygen species (ROS); cellular respiration; antioxidant defense; ageing
(This special issue belongs to the Section Mitochondria)
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