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Diagnostics
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Imaging for the Diagnosis of Obstetric and Gynecological Diseases
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Imaging for the Diagnosis of Obstetric and Gynecological Diseases

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: 31 March 2025 | Viewed by 2253

Special Issue Editor

Dr. Nicolae Gica

E-Mail Website
Guest Editor
Department of Obstetrics and Gynecology, “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, Romania
Interests: gynecology; gynecologic oncology; laparoscopy; endometriosis and fertility preservation in women with cancer
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Imaging methods for the diagnosis of obstetric and gynecological diseases involve the use of various imaging techniques such as ultrasound, MRI, and CT scans in order to assess conditions related to women or fetal diseases. These techniques are used often in daily medical activity and, for this reason, our aim is to welcome interesting and educational papers on imaging related to our field. Additionally, imaging plays a crucial role in pregnancy monitoring, fetal development evaluation, and diagnosing other conditions. The accurate interpretation of imaging results is essential in guiding appropriate treatment and management strategies for patients with obstetric and gynecological diseases.

Dr. Nicolae Gica
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • diagnosis
  • imaging
  • gynecology and obstetrics
  • gynecological cancer
  • hysteroscopy
  • ovarian disease

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Published Papers (2 papers)

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Research

19 pages, 6939 KiB  
Article
Quantitative Assessment of Polarization and Elastic Properties of Endometrial Tissue for Precancer/Cancer Diagnostics Using Multimodal Optical Coherence Tomography
by Anton A. Plekhanov, Gennady O. Grechkanev, Elena A. Avetisyan, Maria M. Loginova, Elena B. Kiseleva, Anastasia A. Shepeleva, Alexander A. Moiseev, Alexander A. Sovetsky, Ekaterina V. Gubarkova, Anastasia A. Anina, Angelina M. Shutova, Sergey V. Gamayunov, Grigory V. Gelikonov, Vladimir Y. Zaitsev, Marina A. Sirotkina and Natalia D. Gladkova
Diagnostics 2024, 14(19), 2131; https://doi.org/10.3390/diagnostics14192131 - 25 Sep 2024
Viewed by 697
Abstract
Objectives: The most important phase in the endometrial pathologies diagnostics is the histological examination of tissue biopsies obtained under visual hysteroscopic control. However, the unclear visual diagnostics characteristics of subtle focal endometrial pathologies often lead to selection errors regarding suspicious endometrial lesions [...] Read more.
Objectives: The most important phase in the endometrial pathologies diagnostics is the histological examination of tissue biopsies obtained under visual hysteroscopic control. However, the unclear visual diagnostics characteristics of subtle focal endometrial pathologies often lead to selection errors regarding suspicious endometrial lesions and to a subsequent false pathological diagnosis/underestimation of precancer or early-stage cancer. Methods: In this study, we investigate the potential of Multimodal Optical Coherence Tomography (MM OCT) to verify suspicious endometrial lesion regions before biopsy collection. We study the polarization (by cross-polarization OCT, CP OCT) and elastic (by compression OCT-elastography, C-OCE) properties of ex vivo endometrial tissue samples in normal conditions (proliferative and secretory phases to the menstrual cycle, atrophic endometrium) with endometrial hyperplasia (non-atypical and endometrial intraepithelial neoplasia) and endometrial cancer subtypes (low-grade, high-grade, clear cell and serous). Results: To the best of our knowledge, this is the first quantitative assessment of relevant OCT parameters (depth-resolved attenuation coefficient in co-[Att(co) values] and cross-[(Att(cross) values] polarizations and Young’s elastic modulus [stiffness values]) for the selection of the most objective criteria to identify the clinically significant endometrial pathologies: endometrial intraepithelial neoplasia and endometrial cancer. The study demonstrates the possibility of detecting endometrial pathologies and establishing optimal threshold values of MM OCT criteria for the identification of endometrial cancer using CP OCT (by Att(co) values = 3.69 mm−1, Sensitivity (Se) = 86.1%, Specificity (Sp) = 92.6%; by Att(cross) values = 2.27 mm−1, Se = 86.8%, Sp = 87.0%) and C-OCE (by stiffness values = 122 kPa, Se = 93.2%, Sp = 91.1%). The study also differentiates endometrial intraepithelial neoplasia from non-atypical endometrial hyperplasia and normal endometrium using C-OCE (by stiffness values = 95 kPa, Se = 87.2%, Sp = 90.1%). Conclusions: The results are indicative of the efficacy and potential of clinical implementation of in vivo hysteroscopic-like MM OCT in the diagnosis of endometrial pathologies. Full article
(This article belongs to the Special Issue Imaging for the Diagnosis of Obstetric and Gynecological Diseases)
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15 pages, 2546 KiB  
Article
CT Angiography-Guided Needle Insertion for Interstitial Brachytherapy in Locally Advanced Cervical Cancer
by Alexandra Timea Kirsch-Mangu, Diana Cristina Pop, Alexandru Tipcu, Alexandra Ioana Andries, Gina Iulia Pasca, Zsolt Fekete, Andrei Roman, Alexandru Irimie and Claudia Ordeanu
Diagnostics 2024, 14(12), 1267; https://doi.org/10.3390/diagnostics14121267 - 15 Jun 2024
Viewed by 1127
Abstract
CT angiography might be a suitable procedure to avoid arterial puncture in combined intracavitary and interstitial brachytherapy for cervical cancer curatively treated with combined chemoradiation and brachytherapy boost. Data in the literature about this technique are scarce. We introduced this method and collected [...] Read more.
CT angiography might be a suitable procedure to avoid arterial puncture in combined intracavitary and interstitial brachytherapy for cervical cancer curatively treated with combined chemoradiation and brachytherapy boost. Data in the literature about this technique are scarce. We introduced this method and collected brachytherapy data from patients treated in our department between May 2021 and April 2024. We analyzed the applicator subtype, needle insertion (planned versus implanted), implanted depth and the role of CT angiography in selecting needle trajectories and insertion depths. None of the patients managed through this protocol experienced atrial puncture and consequent hemorrhage. Needle positions were accurately selected with the aid of CT angiography with proper coverage of brachytherapy targets and avoidance of organs at risk. CT angiography is a promising method for guiding needle insertion during interstitial brachytherapy. Full article
(This article belongs to the Special Issue Imaging for the Diagnosis of Obstetric and Gynecological Diseases)
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