Molecular Diagnosis and Management of Heart Disease

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".

Deadline for manuscript submissions: closed (31 May 2023) | Viewed by 2250

Special Issue Editors


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Guest Editor
Department of Cardiology, Shanghai Fifth People’s Hospital, Fudan University, Shanghai 200240, China
Interests: cardiology; arrhythmia; congenital heart disease; dilated cardiomyopathy; coronary heart disease; evidence-based medicine; medical genetics; molecular pathogenesis; diagnosis; treatment

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Guest Editor
Institute of Cardiovascular Sciences, Shanghai Engineering Research Center of Organ Repair, School of Life Science, Shanghai University, Shanghai 200444, China
Interests: exercise; heart failure; non-coding RNA; exosomes
Key Laboratory of Arrhythmias, Ministry of Education of China, Tongji University School of Medicine, Shanghai 200092, China
Interests: dilated cardiomyopathy; myocardial hypertrophy; heart failure; cardiac differentiation; heart development; single-cell RNA sequencing; epigenetics; regulatory network; bioinformatics

Special Issue Information

Dear Colleagues, 

Heart disease, i.e., coronary heart disease, congenital heart disease, rheumatic heart disease, cardiac arrhythmia, cardiomyopathy, heart failure, etc., is a leading cause of substantial morbidity and mortality globally, and one of the most significant challenges in today’s world. Aggregating evidence has convincingly demonstrated that both environmental risk factors (unhealthy diet, physical inactivity, gestation, microbial infection, trauma, and exposure to toxicants) and genetic defects (genetic mutation, copy number variation, chromosomal abnormalities, and aneuploid) contribute to heart disease. Despite the striking progress in treatment, the incidence and prevalence of heart disease seem to be further increasing. Hence, early prevention, diagnosis and subsequently timely treatment are considered critical factors in reducing the mortality and morbidity of heart disease.

This Special Issue entitled “Molecular Diagnosis and Management of Heart Disease” focuses on the most recent and most pioneering advances in diagnosis, treatment, and prevention of heart disease, which occurs from the fetal period to adulthood.

We cordially invite you to submit your new articles, which could be original studies or reviews.

Dr. Yiqing Yang
Dr. Junjie Xiao
Dr. Li Li
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • heart disease
  • diagnosis
  • etiology
  • mechanism
  • treatment
  • prevention
  • epidemiology
  • cardiac surgery
  • cardiac intervention
  • cardiac development

Published Papers (1 paper)

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Review

12 pages, 1204 KiB  
Review
The Use of Brain Natriuretic Peptide in the Evaluation of Heart Failure in Geriatric Patients
by Mihai Marinescu, Violeta Diana Oprea, Aurel Nechita, Dana Tutunaru, Luiza-Camelia Nechita and Aurelia Romila
Diagnostics 2023, 13(9), 1512; https://doi.org/10.3390/diagnostics13091512 - 23 Apr 2023
Cited by 3 | Viewed by 1907
Abstract
Heart failure is one of the main morbidity and mortality factors in the general population and especially in elderly patients. Thus, at the European level, the prevalence of heart failure is 1% in people under 55 years of age but increases to over [...] Read more.
Heart failure is one of the main morbidity and mortality factors in the general population and especially in elderly patients. Thus, at the European level, the prevalence of heart failure is 1% in people under 55 years of age but increases to over 10% in people over 70 years of age. The particularities of the elderly patient, which make the management of heart failure difficult, are the presence of comorbidities, frailty, cognitive impairment and polypharmacy. However, elderly patients are under-represented in clinical trials on the diagnosis and treatment of heart failure. The need for complementary methods (biomarkers) for differential and early diagnosis of heart failure is becoming more and more evident, even in its subclinical stages. These methods need to have increased specificity and sensitivity and be widely available. Natriuretic peptides, in particular B-type natriuretic peptide (BNP) and its fraction NTproBNP, have gained an increasingly important role in the screening, diagnosis and treatment of heart failure in recent years. Full article
(This article belongs to the Special Issue Molecular Diagnosis and Management of Heart Disease)
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