Unusual Cases in Nuclear Medicine

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: closed (30 December 2023) | Viewed by 2195

Special Issue Editor


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Guest Editor
1. Department of Nuclear Medicine, Comenius University in Bratislava and St. Elisabeth Oncology Institute, Bratislava, Slovakia
2. Service de Médecine Nucléaire, Hôpital Tenon AP-HP, Paris, France
Interests: nuclear medicine; PET; SPECT; unusual case; pitfall

Special Issue Information

Dear Colleagues, 

Functional imaging methods of Nuclear Medicine (i.e. conventional scintigraphy and positron emission tomography) find application across wide spectrum of medical specialties, play a documented role in diagnostic and therapeutic management of a wide spectrum of oncological and non-oncological diseases, and the development is still progressing.

In diagnostic Nuclear Medicine, the typical patterns have been identified for pathologies representing the documented indications for individual radiopharmaceuticals. At the same time, every patient´s case is unique. But which cases are unusual? In general, unusual cases are those that provide with innovative information and those that may potentially generate new research questions.

In Nuclear Medicine, beyond the documentation of use of new radiopharmaceutical in early phase of clinical development, the unusual cases include unusual disease or presentation of disease, unusual interaction of radiopharmaceutical used with current medication or with other extrinsic factor(s), unusual biodistribution of radiopharmaceutical used, unusual incidental finding(s) or imaging pitfall(s) or other phenomenon that is not covered yet by current knowledge.

Some unusual cases are obvious on the first sight; however, the identification of the majority of them requires the thorough knowledge of typical patterns and common variations of given pathology studied by given radiopharmaceutical.

Therefore, drawing the attention to unusual cases in Nuclear Medicine and making them available for general scientific discussion importantly contributes to increase of general knowledge and may open the way to innovative directions in clinical research.

The primary goal of this Special Issue devoted to Unusual Cases in Nuclear Medicine is to communicate such unusual cases and to discuss each of them in the context of current knowledge, all that in order to continuously improve our daily practice.

Dr. Soňa Balogová
Guest Editor

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Keywords

  • positron emission tomography
  • conventional scintigraphy
  • unusual case
  • pitfall

Published Papers (2 papers)

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3 pages, 1011 KiB  
Interesting Images
Mirror Image of Spontaneous Intracranial Hemorrhage
by Xiao Dong, Yuanyuan Liu, Xuehong Chu, Erlan Yu, Xiaole Jia and Chuanjie Wu
Diagnostics 2024, 14(4), 357; https://doi.org/10.3390/diagnostics14040357 - 6 Feb 2024
Viewed by 796
Abstract
In this paper, we reported the first case of mirrored spontaneous intracranial hemorrhage with almost identical hematoma morphological characteristics. This patient’s first symptom was loss of consciousness, without any local neurological symptoms. This clinical presentation fits well with the atypical computed tomography (CT) [...] Read more.
In this paper, we reported the first case of mirrored spontaneous intracranial hemorrhage with almost identical hematoma morphological characteristics. This patient’s first symptom was loss of consciousness, without any local neurological symptoms. This clinical presentation fits well with the atypical computed tomography (CT) image showing bilateral hematomas, and indicates that the distribution of hypertensive vascular damage may be symmetric and that the degree of the bilateral lesions may be similar. Full article
(This article belongs to the Special Issue Unusual Cases in Nuclear Medicine)
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4 pages, 1322 KiB  
Interesting Images
One Fell Swoop: Septic Muscle Embolism and Central Venous Catheter Infection Imaged with [18F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography
by Luca Filippi, Annamaria Lacanfora and Francesco Garaci
Diagnostics 2024, 14(2), 180; https://doi.org/10.3390/diagnostics14020180 - 14 Jan 2024
Viewed by 764
Abstract
We describe the case of a 43-year-old female with hereditary hemochromatosis, previously without cardiac issues, who presented with a severe fever (>40 to 41 °C) to our hospital. Initial assessments, including transthoracic echocardiography, showed no typical signs of infective endocarditis. A contrast-enhanced CT [...] Read more.
We describe the case of a 43-year-old female with hereditary hemochromatosis, previously without cardiac issues, who presented with a severe fever (>40 to 41 °C) to our hospital. Initial assessments, including transthoracic echocardiography, showed no typical signs of infective endocarditis. A contrast-enhanced CT scan revealed a hypodense area in the right subscapular muscle, alongside pleural thicknesses. Due to the critical condition, a central venous catheter (CVC) was implanted for immediate intravenous treatment. Subsequent blood cultures, positive for Staphylococcus aureus, and transesophageal echocardiography led to a diagnosis of multivalvular infective endocarditis (MIE). Subsequently, the patient underwent positron emission tomography/computed tomography (PET/CT) with [18F]Fluorodeoxyglucose ([18F]FDG), which detected increased tracer incorporation in the muscle lesion, CVC, and pleural thicknesses. The final diagnosis was CVC infection and septic embolism to the subscapular muscle in a patient with pleuritis. This case showcases the critical role of [18F]FDG PET/CT as whole-body imaging modality in diagnosing and managing complex infective cases. Full article
(This article belongs to the Special Issue Unusual Cases in Nuclear Medicine)
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