Advances in the Diagnosis and Management of Digestive System Diseases
A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".
Deadline for manuscript submissions: 31 January 2025 | Viewed by 415
Special Issue Editor
Special Issue Information
Dear Colleagues,
Although substantial advancements in the diagnosis and management of digestive system diseases have been achieved in recent years, we are still facing various challenges and dilemmas in dealing with these conditions in daily clinical practice.
To help understand and cope with these disorders, this Special Issue will focus on updates of pathogenesis, diagnosis criteria/consensus, and therapy guidelines, emphasizing efforts in tackling diagnosis and treatment difficulties.
SARS-CoV-2-induced injury in the digestive system is a significant component of COVID-19-caused mortality and mobility. Emerging microorganisms, especially drug-resistant ones, are increasingly identified in the digestive system and need special attention. Inflammatory diseases such as celiac disease, eosinophilic esophagitis/eosinophilic gastroenteritis, inflammatory bowel disease (IBD), and inflammatory bowel syndrome are still a heavy burden in healthcare, with a need for new diagnostic workups/biomarkers, therapeutic modalities, and methods evaluating therapy response. Accurate and timely diagnosis and treatment of gastroesophageal reflux disease (GERD) are still regarded as a challenging area, especially the effectiveness of preventing its progression into Barett's esophagus with currently available treatments. Inflammatory diseases of the liver, including hepatitis B virus infection and primary biliary and primary sclerosing cholangitis (PSC), have insufficient therapy responses in a significant subset of patients. The annual incidences of esophageal adenocarcinoma and colon cancer have continuously increased in the past decade(s), especially in young adults, which necessitates early diagnosis and more effective surveillance strategies and calls for more precisive management of precursor lesions in Barrett's esophagus, IBD and PSC. Molecular monitoring of minimal residual disease (MRD) in managing diagnosed GI malignancies offers predictive and prognostic value. The optimization of treatment of early GI cancers such as pT1 colon cancer is still an unmet need. Liver transplantation is the treatment of choice for liver cancer and liver failure. While acute cellular rejection is amenable to immune suppressors, chronic rejection and antibody-mediated rejection in graft survival are not well understood and remain major challenges in liver transplantation.
We invite authors to contribute knowledge in pathogenesis, diagnosis, and advanced therapies for digestive system diseases.
Dr. Jialing Huang
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- digestive system
- pathology
- liver transplantation
- diagnosis
- therapy
