Diagnostic and Clinical Application of Magnetic Resonance Imaging—2nd Edition

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: 31 January 2025 | Viewed by 1019

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Bioengineering Unit, Fondazione Toscana G. Monasterio, 56124 Pisa, Italy
Interests: magnetic resonance imaging
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Special Issue Information

Dear Colleagues,

The recent technical progress in magnetic resonance imaging (MRI) spatial resolution and sensitivity and the continuous development of new sequences have ensured that this technique remains widely used in all fields of medicine.

MRI can display tissue and body fluid characteristics, and for these reasons, it has become among the most heavily used medical imaging techniques for the diagnosis and follow-up of diseases affecting different organs and tissues.

This Special Issue aims to provide an overview of the potential impact of MRI on the diagnosis and prognosis of different pathologies. Moreover, we provide an update on the recent advances in clinical and research applications of MRI.

We are looking for original research articles that discuss recent advances in MRI techniques, either alone or in combination with future directions of MRI. Relevant review articles and technical notes may also be considered.

Dr. Francesca Frijia
Guest Editor

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Keywords

  • whole-body magnetic resonance imaging
  • neuro magnetic resonance imaging
  • cardiac magnetic resonance imaging
  • MR hardware development for clinical applications
  • deep learning and artificial intelligence in MR imaging
  • advanced MR image acquisition and reconstruction techniques for clinical application

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Published Papers (1 paper)

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Research

16 pages, 2613 KiB  
Article
Biatrial and Biventricular Reference Ranges Based on Cardiac Magnetic Resonance in Sickle Cell Disease Patients Without Heart Damage
by Laura Pistoia, Antonella Meloni, Vincenzo Positano, Alessandra Quota, Elisabetta Corigliano, Giuseppe Messina, Stefania Renne, Michela Zerbini, Simona Romani, Gianfranco Sinagra, Lamia Ait Ali, Sophie Mavrogeni, Amalia Lupi, Filippo Cademartiri and Alessia Pepe
Diagnostics 2024, 14(24), 2816; https://doi.org/10.3390/diagnostics14242816 - 14 Dec 2024
Viewed by 781
Abstract
Background/Objectives: We aimed to establish biatrial and biventricular reference ranges using cardiac magnetic resonance (CMR) parameters in SCD patients without heart damage. Methods: This study compared CMR parameters, quantified by cine SSFP sequences, in 48 adult SCD patients without apparent cardiac involvement (defined [...] Read more.
Background/Objectives: We aimed to establish biatrial and biventricular reference ranges using cardiac magnetic resonance (CMR) parameters in SCD patients without heart damage. Methods: This study compared CMR parameters, quantified by cine SSFP sequences, in 48 adult SCD patients without apparent cardiac involvement (defined by the absence of known risk factors, normal electrocardiogram, and no macroscopic myocardial fibrosis or significant cardiac iron on T2* CMR) to matched cohorts of 96 healthy controls and 96 thalassemia major (TM) patients without cardiac damage. Nine paediatric SCD patients were also analysed and compared to age- and gender-matched groups of nine TM patients and nine healthy subjects. Results: In all groups, studied males displayed higher biventricular volumes and mass indexes than females. Male SCD patients showed significantly higher left ventricular (LV) end-diastolic volume index (EDVI), LV end-systolic volume index (ESVI), LV stroke volume index (SVI), cardiac index, LV and right ventricular (RV) mass index, and atrial areas than healthy subjects. Females with SCD exhibited increased LV EDVI, LV SVI, RV mass index, and left atrial area index compared to healthy controls. SCD and TM patients showed comparable biatrial areas and biventricular volumes and function. When compared to TM, SCD males exhibited a larger mass index, while SCD females showed an increased RV mass index. CMR parameters were similar across all paediatric groups. Conclusions: By establishing the biatrial and biventricular reference ranges through CMR for adult male and female SCD patients, we aimed to prevent possible misdiagnosis of cardiomyopathy in this population by taking into account cardiac adaptation due to anaemia. Full article
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