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Diagnostics
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Advances in Endoscopic Ultrasound
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Advances in Endoscopic Ultrasound

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Optical Diagnostics".

Deadline for manuscript submissions: closed (28 February 2023) | Viewed by 11990

Special Issue Editor

Prof. Dr. Andrada Seicean

E-Mail Website
Guest Editor
1. Department of Gastroenterology, Iuliu Hațieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania
2. Department of Gastroenterology, Regional Institute of Gastroenterology and Hepatology “Prof. Dr. Octavian Fodor”, Cluj-Napoca, Romania
Interests: chronic pancreatitis; pancreas; pancreatic cancer; acute pancreatitis; endoscopy; EUS; pancreatic diseases; biliary tract diseases; pancreatic ductal carcinoma; gastrointestinal diseases
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues, 

Endoscopic ultrasound provides high-resolution, real-time imaging of the gastrointestinal tract and surrounding extramural structures. It plays a great role in the diagnosis and management of gastrointestinal malignancy, pancreatic diseases, and biliary diseases, and continues to evolve.

This Special Issue focuses on the challenges and recent advances in the diagnosis (imaging, differential diagnosis) and management (guided microinvasive treatment, follow-up) of abdominal diseases, such as pancreatic and biliary lesions, the drainage of pancreatic fluid collections and the biliary tree, the treatment of gastrointestinal hemorrhage, celiac plexus neurolysis, fiducial placement, solid and cystic tumor ablation, etc.

Authors can submit original articles, reviews, or short communications.

Prof. Dr. Andrada Seicean
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (5 papers)

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Research

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11 pages, 1988 KiB  
Article
Clinical Utility of the Contrast-Enhanced Endoscopic Ultrasound Guided Fine Needle Aspiration in the Diagnosis of Pancreatic Cyst
by Miruna Patricia Olar, Sorana D. Bolboacă, Cristina Pojoga, Ofelia Moșteanu, Marcel Gheorghiu, Radu Seicean, Ioana Rusu, Zeno Sparchez, Nadim Al Hajjar and Andrada Seicean
Diagnostics 2022, 12(9), 2209; https://doi.org/10.3390/diagnostics12092209 - 12 Sep 2022
Cited by 6 | Viewed by 1876
Abstract
Endoscopic ultrasound fine needle aspiration (EUS-FNA) cytology from an intracystic fluid is useful in the differentiation of pancreatic cysts, with low sensitivity, which increases when the solid component is targeted. The clinical utility of contrast-enhanced guided EUS-FNA (CH-EUS-FNA) in the solid component is [...] Read more.
Endoscopic ultrasound fine needle aspiration (EUS-FNA) cytology from an intracystic fluid is useful in the differentiation of pancreatic cysts, with low sensitivity, which increases when the solid component is targeted. The clinical utility of contrast-enhanced guided EUS-FNA (CH-EUS-FNA) in the solid component is not known. We aimed to assess the diagnostic value of CH-EUS-FNA in enhanced mural nodules and discrimination between different cysts using contrast-enhanced endoscopic ultrasound (CH-EUS). The prospective study recruited patients with pancreatic cysts with an unclear diagnosis. The CH-EUS was followed by CH-EUS-FNA. The final diagnosis was based on surgery or the correlation between clinical history, cross-sectional imaging, echoendoscopic morphology, cystic fluid analysis, and follow-up. Fifty-eight patients with pancreatic cysts were evaluated. The mucinous cysts had wall arterial enhancement more often than non- mucinous cysts (p < 0.0001), with 90.2% sensitivity and 70.6% specificity. The CH-EUS-FNA from cystic fluid and mural nodules identified mucinous cysts and malignancy with 82.4% and 84.2% sensitivity and 92% and 100% specificity. Twenty-one cysts had solid components, but only 13 were enhanced mural nodules on EUS assessment with conclusive cytology in all cases and malignancy in 76.9%. Contrast-enhanced endoscopic ultrasound should be completed in all PCN with solid components in order to avoid unnecessary EUS-FNA and to guide FNA for the identification of malignant cysts. Full article
(This article belongs to the Special Issue Advances in Endoscopic Ultrasound)
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Review

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17 pages, 5143 KiB  
Review
Endoscopic Ultrasound (EUS) Guided Elastography
by Julio Iglesias-Garcia, Daniel de la Iglesia-Garcia, Jose Lariño-Noia and Juan Enrique Dominguez-Muñoz
Diagnostics 2023, 13(10), 1686; https://doi.org/10.3390/diagnostics13101686 - 10 May 2023
Cited by 6 | Viewed by 2849
Abstract
Endoscopic ultrasound (EUS) is an essential technique for the management of several diseases. Over the years, new technologies have been developed to improve and overcome certain limitations related to EUS-guided tissue acquisition. Among these new methods, EUS-guided elastography, which is a real-time method [...] Read more.
Endoscopic ultrasound (EUS) is an essential technique for the management of several diseases. Over the years, new technologies have been developed to improve and overcome certain limitations related to EUS-guided tissue acquisition. Among these new methods, EUS-guided elastography, which is a real-time method for the evaluation of tissue stiffness, has arisen as one of the most widely recognized and available. At present, there are available two different systems to perform an elastographic evaluation: strain elastography and shear wave elastography. Strain elastography is based on the knowledge that certain diseases lead to a change in tissue hardness while shear wave elastography monitored shear-wave propagation and measures its velocity. EUS-guided elastography has shown in several studies high accuracy in differentiating benign from malignant lesions from many different locations, mostly in the pancreas and lymph nodes. Therefore, nowadays, there are well-established indications for this technology, mainly for supporting the management of pancreatic diseases (diagnosis of chronic pancreatitis and differential diagnosis of solid pancreatic tumors) and characterization of different diseases. However, there are more data on new potential indications for the near future. In this review, we will present the theoretical bases of this technology and we will discuss the scientific evidence to support its use. Full article
(This article belongs to the Special Issue Advances in Endoscopic Ultrasound)
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12 pages, 546 KiB  
Review
Approaching Small Neuroendocrine Tumors with Radiofrequency Ablation
by Gemma Rossi, Maria Chiara Petrone, Andrew J. Healey and Paolo Giorgio Arcidiacono
Diagnostics 2023, 13(9), 1561; https://doi.org/10.3390/diagnostics13091561 - 27 Apr 2023
Cited by 1 | Viewed by 1805
Abstract
In recent years, small pancreatic neuroendocrine tumors (pNETs) have shown a dramatic increase in terms of incidence and prevalence, and endoscopic ultrasound (EUS) radiofrequency ablation (RFA) is one potential method to treat the disease in selected patients. As well as the heterogeneity of [...] Read more.
In recent years, small pancreatic neuroendocrine tumors (pNETs) have shown a dramatic increase in terms of incidence and prevalence, and endoscopic ultrasound (EUS) radiofrequency ablation (RFA) is one potential method to treat the disease in selected patients. As well as the heterogeneity of pNET histology, the studies reported in the literature on EUS-RFA procedures for pNETs are heterogeneous in terms of ablation settings (particularly ablation powers), radiological controls, and radiological indications. The aim of this review is to report the current reported experience in EUS-RFA of small pNETs to help formulate the procedure indications and ablation settings. Another aim is to evaluate the timing and the modality of the radiological surveillance after the ablation. Moreover, new studies on large-scale series are needed in terms of the safety and long-term oncological efficacy of RFA on these small lesions. Full article
(This article belongs to the Special Issue Advances in Endoscopic Ultrasound)
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13 pages, 318 KiB  
Review
The Use of Endoscopic Ultrasonography in Inflammatory Bowel Disease: A Review of the Literature
by Răzvan-Cristian Statie, Dan Nicolae Florescu, Dan-Ionuț Gheonea, Bogdan Silviu Ungureanu, Sevastița Iordache, Ion Rogoveanu and Tudorel Ciurea
Diagnostics 2023, 13(3), 568; https://doi.org/10.3390/diagnostics13030568 - 3 Feb 2023
Cited by 4 | Viewed by 1735
Abstract
The diagnosis of inflammatory bowel disease (IBD) can sometimes be challenging. By corroborating clinical, imaging and histological data, the two main entities of IBD, ulcerative colitis and Crohn’s disease (CD), can be differentiated in most cases. However, there remains 10–20% of patients where [...] Read more.
The diagnosis of inflammatory bowel disease (IBD) can sometimes be challenging. By corroborating clinical, imaging and histological data, the two main entities of IBD, ulcerative colitis and Crohn’s disease (CD), can be differentiated in most cases. However, there remains 10–20% of patients where the diagnosis cannot be accurately established, in which case the term “IBD unclassified” is used. The imaging techniques most used to evaluate patients with IBD include colonoscopy, ultrasonography and magnetic resonance imaging. Endoscopic ultrasonography is mainly recommended for the evaluation of perianal CD. Through this work, we aim to identify other uses of this method in the case of patients with IBD. Full article
(This article belongs to the Special Issue Advances in Endoscopic Ultrasound)
14 pages, 958 KiB  
Review
Advances in the Diagnosis of Pancreatic Cystic Lesions
by Claudia Irina Pușcașu, Mihai Rimbaş, Radu Bogdan Mateescu, Alberto Larghi and Victor Cauni
Diagnostics 2022, 12(8), 1779; https://doi.org/10.3390/diagnostics12081779 - 22 Jul 2022
Cited by 8 | Viewed by 2975
Abstract
Pancreatic cystic lesions (PCLs) are a heterogenous group of lesions ranging from benign to malignant. There has been an increase in PCLs prevalence in recent years, mostly due to advances in imaging techniques, increased awareness of their existence and population aging. Reliable discrimination [...] Read more.
Pancreatic cystic lesions (PCLs) are a heterogenous group of lesions ranging from benign to malignant. There has been an increase in PCLs prevalence in recent years, mostly due to advances in imaging techniques, increased awareness of their existence and population aging. Reliable discrimination between neoplastic and non-neoplastic cystic lesions is paramount to ensuring adequate treatment and follow-up. Although conventional diagnostic techniques such as ultrasound (US), magnetic resonance imaging (MRI) and computer tomography (CT) can easily identify these lesions, assessing the risk of malignancy is limited. Endoscopic ultrasound (EUS) is superior to cross-sectional imaging in identifying potentially malignant lesions due to its high resolution and better imaging characteristics, and the advantage of allowing for cyst fluid sampling via fine-needle aspiration (FNA). More complex testing, such as cytological and histopathological analysis and biochemical and molecular testing of the aspirated fluid, can ensure an accurate diagnosis. Full article
(This article belongs to the Special Issue Advances in Endoscopic Ultrasound)
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