Fermentation and Bioactive Potential of Kombucha and Bee-Derived Compounds for Health and Wellness

A special issue of Fermentation (ISSN 2311-5637). This special issue belongs to the section "Probiotic Strains and Fermentation".

Deadline for manuscript submissions: 31 July 2025 | Viewed by 763

Special Issue Editor


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Guest Editor
Faculty of Biotechnology, University of Agricultural Sciences and Veterinary Medicine, Bucharest, Romania
Interests: in vitro; probiotic; prebiotic; biomass; natural extracts; microbiota modulation; kombucha; bee products
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The potential of natural fermentation and bioactive substances in obtaining new health supplements has been studied in many forms in the current context. Focusing on the use of kombucha and bee-derived products, this Special Issue seeks to explore their combined impact on general well-being, oxidative stress control, and microbiome modification. Articles should focus on kombucha's bioactive compounds (organic acids, polyphenols, and enzymes) that enhance gut health and lower oxidative damage by different modulation properties. The unique properties of bee products like honey, propolis, royal jelly, and pollen, primarily targeting anti-inflammatory and antioxidant properties and with possible prebiotic and postbiotic value, will be examined. Papers may contain data on how natural products modulate the gut microbiota fingerprint, their effects on the immune system, and reductions in oxidative stress disorders. Further, this Issue will link conventional fermentation data with industry biotechnological applications by advancing the fabrication of natural supplements with a high efficacy. Researchers are invited to present innovative novel ideas for this project.

Prof. Dr. Emanuel Vamanu
Guest Editor

Manuscript Submission Information

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Keywords

  • green tea
  • postbiotic
  • prebiotic
  • pollen
  • modulation
  • in vitro
  • antioxidant

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Published Papers (1 paper)

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Research

19 pages, 4183 KiB  
Article
Scaling Up Red Ginger Kombucha Fermentation: Insights into Its Chemical Profile and Health-Promoting Properties
by Hani Mulyani, Nina Artanti, Ratna Yuniati and Yasman Yasman
Fermentation 2025, 11(3), 128; https://doi.org/10.3390/fermentation11030128 - 6 Mar 2025
Viewed by 603
Abstract
Red ginger, a plant widely available in Indonesia, is known for its rich content of bioactive compounds, including flavonoids and phenolics, which are known for their strong antioxidant properties. This study explored the fermentation of red ginger extract with kombucha inoculum (SCOBY), aiming [...] Read more.
Red ginger, a plant widely available in Indonesia, is known for its rich content of bioactive compounds, including flavonoids and phenolics, which are known for their strong antioxidant properties. This study explored the fermentation of red ginger extract with kombucha inoculum (SCOBY), aiming to evaluate its potential as a health-enhancing herb with antioxidant and antidiabetic properties by neutralizing free radicals and inhibiting α-glucosidase activity. This study included laboratory-scale (100 mL) and large-scale (10 L) fermentation using 10% red ginger concentration and 15% red ginger kombucha SCOBY for fermentation periods of 0, 7, and 14 days at room temperature. The analysis included sugar content (glucose, fructose, and maltose), organic acids (acetic acid, lactic acid, and gluconic acid), pH, total titrated acids, total polyphenols (Folin–Ciocalteu), and total flavonoids (AlCl3). Fermented red ginger kombucha showed high levels of acetic, lactic, and gluconic acids, along with minor components such as phenolic acids, indicating its potential health benefits as a natural antioxidant. Red ginger kombucha showed significant antioxidant and antidiabetic activity, indicating its potential in managing conditions such as prediabetes and type 2 diabetes. The results of the fermented ginger study showed potential as a health drink with antioxidant and antidiabetic properties given its ability to reduce free radicals and inhibit the activity of the enzyme α-glucosidase. Full article
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