Developments in the Interrelation of Gut Microbiota and Immune System for Treatment Strategies
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".
Deadline for manuscript submissions: 20 October 2025 | Viewed by 1457
Special Issue Editor
Interests: in vitro; extraction; microbiota; functional products; mushrooms
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In humans, the gut microbiota is known to impact the host’s immune system health and functioning, showing great importance in health and disease. More recent findings draw attention to the complex interplay between the gut microbiota and the innate immune system, with special regard to gut microbiota dynamics as a perspective in therapeutic regimens. The gut microbial imbalance during dysbiosis is classically associated with inflammatory and autoimmune diseases and is known to impact the success of therapeutic measures such as vaccines and cancer therapy. This Special Issue seeks to comprehensively discuss the latest developments in modulating and understanding the gut microbiota and immune system interplay.
We welcome original research, reviews, and clinical reports aimed at characterizing microbiota and immune system interactions and their therapeutic potential in relation to holistic treatment. Suggested topics include the following:
Principles shaping innate and adaptive immunity by the microbiota;
Influence of microbiota on the safety and effectiveness of immunotherapy, cancer vaccines and checkpoint inhibitors;
Modulation of immune response by employing strategic microbiota manipulation;
Influence of certain groups of bacteria like Bifidobacterium.
Prof. Dr. Emanuel Vamanu
Guest Editor
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Keywords
- gut microbiota
- innate immune system
- immunotherapy
- dysbiosis
- bifidobacterium
- microbiota modulation
- probiotics
- prebiotics
- symbiotics
- postbiotics
- cancer immunotherapy
- autoimmune diseases
- vaccine response
- immune regulation
- therapeutic microbiology
- translational medicine
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